Copyright
Elsevier (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - October 21, 2023 Category: Infectious Diseases Source Type: research

Contributors
HELEN W. BOUCHER, MD, FACP, FIDSA (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - October 21, 2023 Category: Infectious Diseases Source Type: research

Contents
Sage B. Greenlee and Emily S. Spivak (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - October 21, 2023 Category: Infectious Diseases Source Type: research

Forthcoming Issues
Hot Topics in Lung Infections (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - October 21, 2023 Category: Infectious Diseases Source Type: research

Antimicrobial Stewardship in Immunocompromised Patients
Immunocompromised (IC) patients are high risk for complications due to a high rate of antibiotic exposure. Antimicrobial stewardship interventions targeted to IC patients can be challenging due to limited data in this population and a high risk of severe infection-related outcomes. Here, the authors review immunocompromised antimicrobial stewardship barriers, metrics, and opportunities for antimicrobial use and testing optimization. Last, the authors highlight future steps in the field. (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - September 21, 2023 Category: Infectious Diseases Authors: Jonathan Hand, Hannah Imlay Source Type: research

Principles and Practice of Antimicrobial Stewardship Program Resource Allocation
Antimicrobial Stewardship Programs (ASP) improve individual patient outcomes and clinical care processes while reducing antimicrobial-associated adverse events, optimizing operational priorities, and providing institutional cost savings. ASP composition, resources required, and priority focuses are influenced by myriad factors. Despite robust evidence and broad national support, individual ASPs still face challenges in obtaining appropriate resources. Though understanding the current landscape of ASP resource allocation, factors influencing staffing needs, and strategies required to obtain desired resources is important, a...
Source: Infectious Diseases Clinics of North America - September 19, 2023 Category: Infectious Diseases Authors: George E. Nelson, Navaneeth Narayanan, Sharon Onguti, Kim Stanley, Jason G. Newland, Sarah B. Doernberg Source Type: research

Antimicrobial Stewardship: Reflections and the Road Ahead
Antimicrobial Stewardship existed long before its coined terminology. Yet, since the last issue of Infectious Disease Clinics of North America focused on antimicrobial stewardship nearly a decade ago, the field has undergone exponential growth due to heightened awareness of antimicrobial use and antimicrobial-associated adverse effects, and the continued emergence of multidrug-resistant organisms. In addition, health care and public health governing bodies in the United States have significantly contributed to antimicrobial stewardship growth and awareness through development of detailed guidance around antimicrobial stewa...
Source: Infectious Diseases Clinics of North America - September 1, 2023 Category: Infectious Diseases Authors: Sage B. Greenlee, Emily S. Spivak Tags: Preface Source Type: research

Development of Inpatient Stewardship Metrics
Given the complexity and nuance needed to make antimicrobial prescribing decisions, metrics aiming to assess these decisions can be complex in method, require resource investment for measurement, and demand thoughtfulness in how to use data for program implementation and messaging to key partners. Antimicrobial stewardship programs today use several metrics of antimicrobial use in parallel with other clinical data for a multitude of purposes and audiences. Here, we discuss goals for inpatient stewardship metrics, current metrics used by stewardship programs locally and nationally, and future directions for antimicrobial us...
Source: Infectious Diseases Clinics of North America - September 1, 2023 Category: Infectious Diseases Authors: Rebekah Moehring, Valerie M. Vaughn Source Type: research

Antimicrobial Stewardship: Where We Have Come and Where We Are Going
Antimicrobial Stewardship existed long before its coined terminology. Yet, since the last issue of Infectious Disease Clinics of North America focused on antimicrobial stewardship nearly a decade ago, the field has undergone exponential growth due to heightened awareness of antimicrobial use and antimicrobial-associated adverse effects, and the continued emergence of multidrug-resistant organisms. In addition, health care and public health governing bodies in the United States have significantly contributed to antimicrobial stewardship growth and awareness through development of detailed guidance around antimicrobial stewa...
Source: Infectious Diseases Clinics of North America - September 1, 2023 Category: Infectious Diseases Authors: Sage B. Greenlee, Emily S. Spivak Tags: Preface Source Type: research

Health System and Tele-Antimicrobial Stewardship
Tele-antimicrobial stewardship programs (tele-ASPs) use technology and remote access to resources and clinical expertise to expand antimicrobial services within and outside of health systems. Models of tele-ASPs are workforce multiplying and workforce extending, depending on how they are structured. Building rapport and strong interpersonal networks are essential for successful ASPs. The available evidence suggests that an optimal model for tele-ASP includes hands-on involvement from remote infectious disease (ID) expertise with implementation by local pharmacists. However, this model remains limited by the available time ...
Source: Infectious Diseases Clinics of North America - August 30, 2023 Category: Infectious Diseases Authors: Zahra Kassamali Escobar, Nathan R. Shively Source Type: research

Next Steps in Ambulatory Stewardship
Most antibiotics are prescribed in ambulatory setting and at least 30% to 50% of these prescriptions are unnecessary. The use of antibiotics when not needed promotes the development of antibiotic resistant organisms and harms patients by placing them at risk for adverse drug events and Clostridioides difficile infections. National guidelines recommend that health systems implement antibiotic stewardship programs in ambulatory settings. However, uptake of stewardship in ambulatory setting has remained low. This review discusses the current state of ambulatory stewardship in the United States, best practices for the successf...
Source: Infectious Diseases Clinics of North America - August 26, 2023 Category: Infectious Diseases Authors: Holly M. Frost, Adam L. Hersh, David Y. Hyun Source Type: research

Antimicrobial Stewardship and Pandemic Preparedness: Harnessing Lessons Learned to Advance Our Mission
Antimicrobial stewardship programs (ASPs) demonstrated poise and resilience in assisting with COVID-19 efforts across the globe, harnessing expertise in diagnostic stewardship, therapeutics, protocol development, and use of technology to rapidly expand their scope through strategic collaborations, dissemination of content expertise, and numerous contributions to the body of knowledge on COVID-19. Lessons learned from pandemic response should be used to advance the mission of ASPs and secure a “seat at the table” as health systems continue to expand and adapt to future public health crises. (Source: Infectious Diseases ...
Source: Infectious Diseases Clinics of North America - August 20, 2023 Category: Infectious Diseases Authors: Terrence McSweeney, Mei H. Chang, Payal Patel, Priya Nori Source Type: research

What Is Left to Tackle in Inpatient Antimicrobial Stewardship Practice and Research
This article discusses current antimicrobial stewardship practice challenges and ways to improve current antimicrobial stewardship workflows. Additionally, we propose new workflows that further engage front line clinicians in optimizing their own antibiotic decision making. (Source: Infectious Diseases Clinics of North America)
Source: Infectious Diseases Clinics of North America - August 14, 2023 Category: Infectious Diseases Authors: Jacqueline T. Bork, Emily L. Heil Source Type: research

Antimicrobial Stewardship at Transitions of Care
Antimicrobial stewardship interventions have historically been siloed in different care settings; recently, a need for stewardship interventions at care transitions has arisen as inappropriate prescribing at care transitions may result in patient harm. There are several care areas that should be considered for optimizing antibiotic prescribing. Interventions can be difficult to implement as they often require the efforts of a multidisciplinary team and are resource intensive. Antimicrobial stewardship programs should prioritize interventions at transitions of care to improve prescribing and patient outcomes. (Source: Infec...
Source: Infectious Diseases Clinics of North America - August 12, 2023 Category: Infectious Diseases Authors: Lisa E. Dumkow, Abigail C. Geyer, Lisa E. Davidson Source Type: research

Demographic and Geographic Inequities in Antimicrobial Use and Prescribing
Little is known about how social determinants of health may impact antimicrobial prescribing among racial and ethnic minority populations, different age groups and genders, and across geographic regions. The factors that influence antimicrobial prescribing are complex, but evidence suggests that demographic and socioeconomic factors do influence prescribing patterns. This review describes the inequities observed in antimicrobial use and prescribing that have been heretofore published, with a focus on differences observed by race and ethnicity, age, gender, and geographic region of the United States. (Source: Infectious Dis...
Source: Infectious Diseases Clinics of North America - August 9, 2023 Category: Infectious Diseases Authors: Christopher Evans, Zanthia Wiley Source Type: research