Safety and efficacy of non-reduced use of caspofungin in patients with Child –Pugh B or C cirrhosis: a real-world study
ConclusionsStandard-dose of caspofungin can be safely and effectively used in patients with Child –Pugh B or C cirrhosis, and we appealed to re-assess the most suitable dosing regimen in this population to avoid a potential subtherapeutic exposure. (Source: Infection)
Source: Infection - January 24, 2024 Category: Infectious Diseases Source Type: research
Risk factors for herpes zoster infections: a systematic review and meta-analysis unveiling common trends and heterogeneity patterns
ConclusionsThis study showed an increased risk of HZ infections for all identified factors. (Source: Infection)
Source: Infection - January 18, 2024 Category: Infectious Diseases Source Type: research
Successful treatment of glandular tularemia with azithromycin in a pregnant woman in Austria
AbstractTreatment of tularemia during pregnancy is challenging due to toxicity of standard treatment regimens. Here, we report a 31-year-old woman with glandular tularemia who was successfully treated with intravenous azithromycin. Follow-up examinations over a 6-month period showed a sustained response to treatment. She later gave birth to a healthy child. (Source: Infection)
Source: Infection - January 11, 2024 Category: Infectious Diseases Source Type: research
EG.5 (Eris) and BA.2.86 (Pirola) two new subvariants of SARS-CoV-2: a new face of old COVID-19
ConclusionBased on the currently available data these two new subvariants have similar features with currently circulating variants of Omicron and are less immune evasive than ancestral SARS-CoV-2. (Source: Infection)
Source: Infection - January 3, 2024 Category: Infectious Diseases Source Type: research
Experience with dalbavancin use in various gram-positive infections within Aberdeen Royal Infirmary OPAT service
ConclusionThis report adds to clinical experience with dalbavancin for off-label indications whilst further validating its role in ABSSSI. Dalbavancin as primary therapy in deep-seated infections merits investigation in formal clinical trials. (Source: Infection)
Source: Infection - January 2, 2024 Category: Infectious Diseases Source Type: research
Prospective assessment of the frequency of and risk factors for bleeding events in patients treated with cefazolin
ConclusionsBleeding events associated with cefazolin treatment are frequent. Close clinical monitoring should be performed for patients treated for endocarditis and/or receiving vitamin K antagonists. Hemostasis work-up could be restricted to these patients. (Source: Infection)
Source: Infection - December 28, 2023 Category: Infectious Diseases Source Type: research
Rhinocerebral mucormycosis in immunocompetent patients: a case report and review of literature
ConclusionAlthough very rare, mucormycosis can occur in immunocompetent patients. Physicians should consider mucormycosis when faced with refractory conditions and unusual symptoms such as exposed bones, facial numbness, headaches, and intractable pain. Complementary imaging (CT scan with or without MRI) and histopathological examination are critical for timely diagnosis or exclusion of this potentially fatal yet treatable disease. (Source: Infection)
Source: Infection - December 28, 2023 Category: Infectious Diseases Source Type: research
Prospective assessment of the frequency of and risk factors for bleeding events in patients treated with cefazolin
ConclusionsBleeding events associated with cefazolin treatment are frequent. Close clinical monitoring should be performed for patients treated for endocarditis and/or receiving vitamin K antagonists. Hemostasis work-up could be restricted to these patients. (Source: Infection)
Source: Infection - December 28, 2023 Category: Infectious Diseases Source Type: research
Rhinocerebral mucormycosis in immunocompetent patients: a case report and review of literature
ConclusionAlthough very rare, mucormycosis can occur in immunocompetent patients. Physicians should consider mucormycosis when faced with refractory conditions and unusual symptoms such as exposed bones, facial numbness, headaches, and intractable pain. Complementary imaging (CT scan with or without MRI) and histopathological examination are critical for timely diagnosis or exclusion of this potentially fatal yet treatable disease. (Source: Infection)
Source: Infection - December 28, 2023 Category: Infectious Diseases Source Type: research
Lack of microbiological awareness on the ward as a key factor for inappropriate use of anti-infectives: results of a point prevalence study and user satisfaction survey in a large university hospital in Austria
ConclusionA high potential in improving the use of anti-infectives in hospitals seems to lie in a strong emphasis on microbiological diagnostic stewardship measures. (Source: Infection)
Source: Infection - December 27, 2023 Category: Infectious Diseases Source Type: research
