Indian Journal of Medical Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Geographically distinct North-East Indian Helicobacter pylori strains are highly sensitive to clarithromycin but are levofloxacin resistant
Conclusions: Resistance for clarithromycin was less in North-East Indian strains but high for levofloxacin indicating that first-line therapy may be best and effective for eradication of H. pylori in this region. This study is the first report that showed antibiotic susceptibility pattern for clarithromycin and levofloxacin by mutation analysis. By partial sequencing of 23s rRNA and gyraseA gene, we found that North-East Indian strains are geographically distinct. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Shweta Mahant Amresh Kumar Sharma Valentina Gehlot Asish Kumar Mukhopadhyay Ayushi Chhawchharia Sangitanjan Dutta Anil Agarwal Anup Som Kunal Das Rajashree Das Source Type: research

Clonal clusters and virulence factors of methicillin-resistant Staphylococcus Aureus: Evidence for community-acquired methicillin-resistant Staphylococcus Aureus infiltration into hospital settings in Chennai, South India
Conclusion: A total of 769 isolates of S. aureus isolates were studied. The prevalence of MRSA was found to be 7.17%, 81.67%, 58.33% and 22.85% for groups a, b, c and d, respectively. Of the four SCCmec types (I, III, IV and V) detected, SCCmec V was found to be predominant. Panton-Valentine leucocidin toxin genes were detected among MRSA isolates harbouring SCCmec IV and V. A total of 78 spa types were detected, t657 being the most prevalent. 13 MLST types belonging to 9 CC were detected. CC1 (ST-772, ST-1) and CC8 (ST238, ST368 and ST1208) were found to be predominant among MRS...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Nagarajan Abimannan G Sumathi OR Krishnarajasekhar Bhanu Sinha Padma Krishnan Source Type: research

Protocol for developing a surveillance system for surgical site infections
Conclusion: Surveillance is an essential tool to reduce this burden. It is also an important primary step in recognizing problems and priorities, and it plays a crucial role in identifying risk factors for SSI and to be able to target modifiable risk factors. Therefore, it is imperative to establish reliable systems for surveillance of HAIs, to regularly estimate the actual burden of HAIs, and to use these data for developing indigenous preventive measures, tailored to the country's priorities. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Purva Mathur Samarth Mittal Vivek Trikha Ayush Lohiya Surbhi Khurana Sonal Katyal Nidhi Bhardwaj Sushma Sagar Subodh Kumar Rajesh Malhotra Kamini Walia Source Type: research

Assessment of core capacities for antimicrobial stewardship practices in indian hospitals: Report from a multicentric initiative of global health security agenda
Conclusion: The hospitals included a mix of public and private sector hospitals. The network average of positive responses for leadership support was 45%, for accountability; the score was 53% and for key support for AMSP, 58%. Policies to support optimal antibiotic use were present in 59% of respondents, policies for procurement were present in 79% and broad interventions to improve antibiotic use were scored as 33%. A score of 52% was generated for prescription-specific interventions to improve antibiotic use. Written policies for antibiotic use...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Mathur Purva Guleria Randeep Malhotra Rajesh C Misra Mahesh Gupta Sunil Kumar Subodh Sagar Sushma Wig Naveet Garg Pramod Kapil Arti Khurana Surbhi Katoch Omika Katyal Sonal Sahu Manoj Chakrabarti Arunaloke Ray Pallab Biswal Manisha Taneja Neelam Rupali Pr Source Type: research

Topical antimicrobial therapy: Current status and challenges
Pallab Ray, Shreya Singh, Swati GuptaIndian Journal of Medical Microbiology 2019 37(3):299-308 Topically applied antibacterial agents are widely used. Opinions regarding the clinical efficacy of topical antibiotics are conflicting, and for most indications, alternative oral therapies are available. Topical application has many potential advantages over systemic therapy that includes high and sustained concentrations of drug directly at the infected site, low quantity of antibiotic needed, better compliance, fewer systemic side effects and potentially less chance of antimicrobial resistance. Despite these advantages, an im...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Pallab Ray Shreya Singh Swati Gupta Source Type: research

Combined treatment modality for phthiriasis palpebrarum
Chitaranjan Mishra, Usha Kim, Mulasthanam Sai DheeraIndian Journal of Medical Microbiology 2019 37(2):296-297 Phthiriasis palpebrarum (PP) is the infestation of eyelids caused by the ectoparasite Phthirus pubis, frequently misdiagnosed as allergic conjunctivitis, blepharitis or dermatitis. There is no standard treatment of choice although various treatment modalities have been described. A 6-year-old male child with PP was successfully treated with local application of 20% fluorescein solution over the eyelashes and eyebrows of both the eyes, followed by the mechanical removal of all parasites and trimming of t...
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Chitaranjan Mishra Usha Kim Mulasthanam Sai Dheera Source Type: research

Multifocal hepatic abscesses in immunocompetent patient due to Bartonella henselae: Case report with review of literature
Sonu Kumari Agrawal, Prasenjit Das, Shalimar , Gupta Swatantra, Rama ChaudhryIndian Journal of Medical Microbiology 2019 37(2):292-295 To the best of our knowledge, this is the first case of multifocal hepatic abscesses in a young immunocompetent adult from India, which was successfully treated with hepatectomy and short course of oral antibiotic regimen. Publishing further such case reports will provide more clarity regarding the clinical significance of the disease, including associated risk factors and appropriate treatment. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Sonu Kumari Agrawal Prasenjit Das Shalimar Gupta Swatantra Rama Chaudhry Source Type: research

Ocular infection by a psychrophile: Pseudomonas fluorescens
We report a case, wherein we serendipitously isolated Pseudomonas fluorescens – an organism that prefers lower temperatures for optimal growth (psychrophilic) in the environment – from eviscerated contents of an eye with total corneal melt. This case highlights the need for being vigilant for organisms with different temperature sensitivities in culture media than that found in routine protocols. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Sanchita Mitra Suryasnata Rath Sujata Das Soumyava Basu Source Type: research

A typical Escherichia coli: A Dilemma of a Clinical Diagnostic Laboratory
Tonushyam Sonowal, Malini ShariffIndian Journal of Medical Microbiology 2019 37(2):287-288 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Tonushyam Sonowal Malini Shariff Source Type: research

Increase in Chlamydia trachomatis genital and extra-genital infections in Indian males
Sonu Kumari Agrawal, Jyoti Rawre, Neena Khanna, Benu DhawanIndian Journal of Medical Microbiology 2019 37(2):285-286 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Sonu Kumari Agrawal Jyoti Rawre Neena Khanna Benu Dhawan Source Type: research

Detection of cytomegalovirus disease by real-time quantitative PCR targeting immediate early gene (ppUL83) in different samples among post-renal-transplant recipients
Ramya Barani, Vigna Seshan, Yazhini Ravi, Periasamy Soundararajan, Gunasekaran Palani, Padma SrikanthIndian Journal of Medical Microbiology 2019 37(2):281-284 Renal transplantation is a treatment option for end-stage renal disease (ESRD). Cytomegalovirus (CMV) infection was analysed among symptomatic and asymptomatic post-renal-transplant recipients (PRTRs). A total of 30 PRTRs were enrolled. DNA was extracted and quantitative real-time PCR for CMV (CMV R-Gene, France) targeting ppUL83 gene was performed on whole blood, urine and saliva. The detection rate of CMV was found to be 27% (n = 8) in differ...
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Ramya Barani Vigna Seshan Yazhini Ravi Periasamy Soundararajan Gunasekaran Palani Padma Srikanth Source Type: research

Clinico-epidemiological analysis of scrub typhus in hospitalised patients presenting with acute undifferentiated febrile illness: A hospital-based study from Eastern India
Bijayini Behera, Manisha Biswal, Rashmi Ranjan Das, Anupam Dey, Jayanti Jena, Sagarika Dhal, Srujana Mohanty, Baijayantimala Mishra, Ashok Kumar PraharajIndian Journal of Medical Microbiology 2019 37(2):278-280 Acute undifferentiated febrile illness (AUFI) constitutes the predominant cause of healthcare seeking in Odisha. This prospective study was conducted to analyse the clinical, epidemiological and laboratory profile of scrub typhus patients presenting with AUFI from January to December 2017. Four hundred and thirty-two samples were tested for dengue, malaria, scrub typhus and enteric fever. Scrub typhus was overall t...
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Bijayini Behera Manisha Biswal Rashmi Ranjan Das Anupam Dey Jayanti Jena Sagarika Dhal Srujana Mohanty Baijayantimala Mishra Ashok Kumar Praharaj Source Type: research

Gut microbiota and its mysteries
Premalatha Pushpanathan, Gifty Sara Mathew, Sribal Selvarajan, Krishna G Seshadri, Padma SrikanthIndian Journal of Medical Microbiology 2019 37(2):268-277 Gut microbiota are microorganisms that inhabit the gut; they coexist peacefully with the host, thereby contributing to the health and well-being of individuals. Bacteroidetes and Firmicutes largely dominate the gut microbial flora. The intestinal flora promotes intestinal mucosal integrity, provides essential nutrients such as vitamins and enzymes, protects the body against pathogens and produces antimicrobial peptides such as defensins, C-type lectins, cathelicidins, t...
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Premalatha Pushpanathan Gifty Sara Mathew Sribal Selvarajan Krishna G Seshadri Padma Srikanth Source Type: research

Ultrasound gel as a source of hospital outbreaks: Indian experience and literature review
Conclusion: This report highlights the importance of early identification of an outbreak, prompt response of the ICU and infection control teams, sound environmental and epidemiological surveillance methods to identify the source and stringent infection control measures to control the outbreak. Contaminated ultrasound gel can be a potential source for healthcare-associated infection, which cannot be overlooked. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Dhanalakshmi Solaimalai Naveen Kumar Devanga Ragupathi Kala Ranjini Hema Paul Valsan P Verghese Joy Sarojini Michael Balaji Veeraraghavan Ebor Jacob James Source Type: research

Predominance of high-risk human papillomavirus genotype 16 and 39 in women with premalignant and malignant cervical pathology from Raipur, Chhattisgarh: Clinical evaluation of tagging oligonucleotide cleavage and extension mediated genotyping assay
Conclusion: Anyplex HR-HPV assay is arguably the useful assay for better patient management and can be useful for HR-HPV screening by its unique individual genotype identification of all HR-HPV. Finding of HPV 16, 39, 18, 33 and coinfection of 16,18 and 16, 18, 33 in CIN and CC would help vaccine manufacturer to design specific future HPV polyvalent vaccine preparation to curb down the CC-associated mortality. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Sanjay Singh Negi Anudita Bhargava Priyanka Singh Sarita Aggarwal Nighat Hussain Padma Das Source Type: research