Trends of inflammatory bowel disease from the Global Burden of Disease Study (1990-2019)
ConclusionThis analysis of the GBD 2019 database demonstrates that the overall global burden of IBD is lower than previously estimated, but an increasing disease burden is observed in the middle and low-SDI locations.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - October 3, 2023 Category: Gastroenterology Source Type: research
Differences in Coronavirus disease - 19 vaccination related side effects in patients with ulcerative colitis and Crohn ’s disease in Japan
ConclusionThe use of corticosteroids could increase the risk of muscle pain following COVID-19 vaccination. Additionally, factors such as female sex, younger age and current or former smoking can affect the incidence of fever or chills. This information should encourage patients with IBD to get vaccinated against COVID-19. (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - October 1, 2023 Category: Gastroenterology Source Type: research
Current paradigms in the management of refractory Helicobacter pylori infection
AbstractHelicobacter pylori is the most prevalent chronic bacterial infection, with approximately half of the world ’s population estimated to be colonized. The World Health Organization (WHO) has classifiedHelicobacter pylori as a class-I carcinogen. All main society guidelines recommend its eradication in infected individuals. The global trend indicates that eradication rates are decreasing annually and the likelihood of eradication decreases with each unsuccessful therapeutic attempt. Resistance to antibiotics inH. pylori strains is the leading cause for eradication failure. Still, drug resistance and treatment fa...
Source: Indian Journal of Gastroenterology - September 22, 2023 Category: Gastroenterology Source Type: research
Upfront tofacitinib in patients with biological-na ïve ulcerative colitis – An Indian multicentric experience
ConclusionUpfront tofacitinib is effective in biologic-na ïve Indian patients with moderate-severe UC. Further randomized studies are required to validate the study findings.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - September 20, 2023 Category: Gastroenterology Source Type: research
Endoscopic ultrasound for the diagnosis of Budd-Chiari syndrome
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - September 18, 2023 Category: Gastroenterology Source Type: research
Guidelines on optimizing the use of proton pump inhibitors: PPI stewardship
AbstractProton pump inhibitors (PPIs) have been available for over three decades and are among the most commonly prescribed medications. They are effective in treating a variety of gastric acid-related disorders. They are freely available and based on current evidence, use of PPIs for inappropriate indications and duration appears to be common. Over the years, concerns have been raised on the safety of PPIs as they have been associated with several adverse effects. Hence, there is a need for PPI stewardship to promote the use of PPIs for appropriate indication and duration. With this objective, the Indian Society of Gastro...
Source: Indian Journal of Gastroenterology - September 12, 2023 Category: Gastroenterology Source Type: research
Gastroparesis in a patient with benign joint hypermobility syndrome
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - September 7, 2023 Category: Gastroenterology Source Type: research
Transcriptional analysis of Helicobacter pylori cytotoxic-associated gene-pathogenicity island in response to different pH levels and proton pump inhibitor exposure
ConclusionOur results showed that omeprazole could increase the expression ofH. pylori cagA andcagL at acidic pH. Heterogeneity among the strains probably has an impact on the extent of their interplay with PPIs. Further studies are needed to establish this correlation.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - September 4, 2023 Category: Gastroenterology Source Type: research
