A case of leishmania infantum mimicking lymphoma
Gulnaz Culha, A Çiğdem Doğramacı, Tuğba Kaya, İlke Evrim SeçintiIndian Journal of Dermatology 2023 68(1):91-94
Leishmaniasis is a parasitic infection caused by an obligate intracellular protozoon transmitted by infected sand flies. Cutaneous leishmaniasis (CL) is a skin disease known in our country as oriental sore, which heals, leaving a scar in place, mainly on the skin and sometimes in the mucous membrane. Demonstration of the parasite in chronic CL is difficult. Moreover, differential diagnosis from other granulomatous dermatitides suc...
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Gulnaz Culha A & #199;i & #287;dem Do & #287;ramac & #305; Tu & #287;ba Kaya & #304;lke Evrim Se & #231;inti Source Type: research
Emerging treatments for reactive cutaneous capillary endothelial proliferation
Conclusion: New therapies for RCCEP have emerged in recent years. Dermatologists should raise better awareness of the complexity of drug eruption and the need for early diagnosis and medical intervention. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Yi Liu Tiancheng Chen Chao Zhang Weihua Pan Source Type: research
Trichoscopy in alopecia areata and trichotillomania in skin of colour: A comparative study
Siddharth Mani, Aradhana Raut, Shekhar Neema, Manish Khandare, Prateksha Golas, Sunmeet Sandhu, Rohit Kothari, Gopalsing R Rajput, Bhavni OberoiIndian Journal of Dermatology 2023 68(1):78-84
Alopecia areata (AA) and trichotillomania (TTM) are the two common causes of localised non scarring alopecia. While AA is an autoimmune disorder, TTM is an impulse control disorder which makes the treatment of the two entities completely different. Trichoscopy is a non-invasive tool used to diagnose hair disorders, which not only is extremely helpful in diagnosing AA and TTM but also differentiates them from other hair disorders as we...
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Siddharth Mani Aradhana Raut Shekhar Neema Manish Khandare Prateksha Golas Sunmeet Sandhu Rohit Kothari Gopalsing R Rajput Bhavni Oberoi Source Type: research
Hyperacute graft-versus-host disease of the skin following allogeneic stem cell transplantation: A paediatric case series
Gauri D Mahabal, Leni George, Dincy Peter, Meera Thomas, Biju George, Vikram Mathews, Aby Abraham, Alok Srivastava, Susanne PulimoodIndian Journal of Dermatology 2023 68(1):73-77
Hyperacute GVHD (HaGVHD) is a rare complication of hematopoietic stem cell transplantation (HSCT) occurring before engraftment, a syndrome commonly involving skin and/or gut and/or liver, with increased morbidity and mortality. Myeloablative conditioning (MAC) regimes and mismatched donor transplants have an increased risk for HaGVHD. There is a higher chance of steroid-refractoriness and chronic GVHD in those who develop HaGVHD. There is limited...
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Gauri D Mahabal Leni George Dincy Peter Meera Thomas Biju George Vikram Mathews Aby Abraham Alok Srivastava Susanne Pulimood Source Type: research
A cross-sectional study of the levels of cytokines IL-6, TNF- & #945;, and IFN- & #947; in blood and skin (lesional and uninvolved) of vitiligo patients and their possible role as biomarkers
Conclusion: We conclude vitiligo is strongly associated with increased levels of TNF-α and IL 6. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Abhishek De Nidhi Choudhary Amrita Sil Aarti Sarda Abu Hena Hasanoor Raja Source Type: research
Heparanase contributes to psoriatic lesions through crosstalk with IL-17 pathway
Chengyao Zhu, Yunqin Ren, Hongliang Yao, Bo Feng, Lunfei Liu, Min ZhengIndian Journal of Dermatology 2023 68(1):59-66
Psoriasis is a chronic inflammatory disease that is considered by a network of immunocytes and cytokines. Among all, Th17 cells–derived IL-17 is a critical driving factor in the pathogenesis of psoriasis. Recently, disruption of the extracellular matrix was found to be related to psoriasis progression. In the present study, we aimed to investigate the role of heparanase (HPSE) in psoriasis and the crosstalk with the IL-17 signalling pathway. Skin tissues from non-affected areas and psoriatic l...
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Chengyao Zhu Yunqin Ren Hongliang Yao Bo Feng Lunfei Liu Min Zheng Source Type: research
The efficacy of moisturisers containing ceramide compared with other moisturisers in the management of atopic dermatitis: A systematic literature review and meta-analysis
This study aimed to compare the efficacy of moisturisers containing ceramide with other moisturisers for AD management. Searches were conducted systematically on PubMed, the Cochrane Library, ScienceDirect, Clinicaltrials.gov, and Google Scholar for studies published from January 2012 to July 2022. Interventions and outcomes were compared in this study. Statistical analysis was performed with ReviewManager 5.4 software. Five articles met the eligibility and inclusion criteria. Three articles were meta-analyses on trans-epidermal water loss (TEWL) outcomes and two articles were meta-analyses on SCORing Atopic Dermatitis (SC...
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Wisnu Triadi Nugroho Sawitri Sawitri Astindari Astindari Budi Utomo M Yulianto Listiawan Evy Ervianti Linda Astari Source Type: research
Onychoscopy of nail lesions in dermatological disorders: A cross-sectional observational study
Conclusions: Onychocopy can minimize the need for biopsy by highlighting subtle changes and helps narrow down the differentials. It is potentially a diagnostic test of choice in younger children. Our study helped to grade the severity of connective tissue disorders and establish the benignity of melanonychia. Photographic documentation facilitates record-keeping. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Aashna Sutaria Devayani Pol Kalyan Dalave Mahendra S Deora Yugal K Sharma Chintal H Shah Source Type: research
Cutaneous adnexal tumours: A study of 395 cases from a tertiary care hospital
Conclusion: CATs comprise of a wide spectrum of tumours occurring in all age groups. Malignant CATs are rare and common in older age groups. Histopathological examination is the gold standard in distinguishing between the different subtypes. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Nitu Sharma Tripti Nakra Shipra Agarwal Vishal Gupta Manoj Kumar Singh Sudheer Arava Source Type: research
Stevens & #8211;Johnson syndrome and toxic epidermal necrolysis: A fresh look at an old foe
Conclusion: Factors significantly associated with increased mortality in TEN were cutaneous onset of lesions, mean BSA of involvement and transfer to the intensive care unit (ICU) beyond day 7 of admission. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Sowmya Kaimal Carol Lobo Girish Narayan Mary Augustine Source Type: research
Clinicoetiological study of Stevens-Johnson syndrome and toxic epidermal necrolysis spectrum and the correlation of SCORTEN with prognosis
Conclusion: SCORTEN gave a significant estimation of mortality in SJS-TEN overlap patients, whereas it overestimated mortality in TEN patients. An increase in individual scores for the elevation of blood urea nitrogen (BUN) in existing SCORTEN and the inclusion of new parameters like raised liver enzymes, thrombocytopenia, and pulmonary infiltrates aided in proposing a modified SCORTEN for the South Indian population. Further studies on a larger scale, are needed to validate the modified SCORTEN proposed by us. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Amuthavalli Kanagarajan Aravind Baskar Murthy Punithavathi Kailasa Moni Nirmaladevi Palanivel Source Type: research
The changing trend of syphilis: Is it a sign of impending epidemic ?
Conclusion: The increased trend of primary and secondary syphilis in recent years highlights that there is a risk of an impending epidemic. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Mudita Gupta Ghanshyam K Verma Rajni Sharma Manish Sankhyan Renu Rattan Ajeet Kumar Negi Source Type: research
Immune cell profiling of atopic dermatitis patients before and after treatment with halometasone cream wet-wrap therapy by single-cell sequencing
Conclusions: These genes may be new target for further study. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Xiao-Guang Gu Xin Yu Bo-Yang Zhou Ming Li Wei Xu Yan Li Lin-Feng Li Source Type: research
The efficacy and safety of 5-aminolevulinic acid photodynamic therapy for lichen sclerosus: A meta analysis
Conclusions: The current limited evidence supports the efficacy and safety of ALA-PDT in treating LS. The adverse reactions included pain, swelling, redness and exfoliation which would decrease with the continuing sessions of treatment. Further high-qualified RCTs of large samples are necessarily needed. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 31, 2023 Category: Dermatology Authors: Chun Qing Xiaoyong Mao Gaoqing Liu Yibin Deng Xiaokun Yang Source Type: research
Dermoscopy to the rescue
Dharmesh G Parmar, Trisha B Patel, Pragya A NairIndian Journal of Dermatology 2022 67(6):839-839 (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - February 23, 2023 Category: Dermatology Authors: Dharmesh G Parmar Trisha B Patel Pragya A Nair Source Type: research
