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The advance directives and foregoing of life support: Where do we stand now ?
Raj Kumar Mani, Sri Nagesh Simha, Roop GursahaniIndian Journal of Critical Care Medicine 2018 22(3):135-137 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - March 16, 2018 Category: Intensive Care Authors: Raj Kumar Mani Sri Nagesh Simha Roop Gursahani Source Type: research

Allergic angina syndrome in anesthesia and diabetes
Nicholas G Kounis, Ioanna Koniari, George Tzanis, George D Soufras, George HahalisIndian Journal of Critical Care Medicine 2018 22(2):128-129 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Nicholas G Kounis Ioanna Koniari George Tzanis George D Soufras George Hahalis Source Type: research

Cerebral venous thrombosis after intravenous immunoglobulin therapy in immune thrombocytopenic purpura
Mahmood Dhahir Al-MendalawiIndian Journal of Critical Care Medicine 2018 22(2):128-128 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Mahmood Dhahir Al-Mendalawi Source Type: research

Pulmonary nocardiosis: Unusual presentation in Intensive Care Unit
Ashok Kumar Singh, Aditya Shukla, R Bajwa, Roshni Agrawal, Neha SrivastwaIndian Journal of Critical Care Medicine 2018 22(2):125-127 Pulmonary nocardiosis is a rare disease, which mainly affects immunocompromised hosts such as uncontrolled diabetics; HIV patients; and patients on immunosuppressive therapies such as anticancer drugs, systemic steroids, and transplant recipients. The diagnosis is often missed and delayed, resulting in inappropriate treatment and thus higher mortality. We are reporting a case of pulmonary nocardiosis with acute presentation in an immune-competent host, who presented with community-acquired p...
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Ashok Kumar Singh Aditya Shukla R Bajwa Roshni Agrawal Neha Srivastwa Source Type: research

A case of Lemierre & #39;s syndrome in Intensive Care Unit
We report a 21-year-old young male with Lemierre's syndrome presented as tonsillitis and Fusobacterium septicemia with respiratory failure and required intensive care. Lemierre's syndrome is the septic embolic complication of recent pharyngeal illness. Fusobacterium spp. accounts for the majority of cases. High index of suspicion is needed and prolonged antibiotic is advised. It is seldom seen in intensive care but should never be forgotten. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Man-Yee Man Hoi-Ping Shum Wing-Wa Yan Susanna K P. Lau Source Type: research

Recurrent metabolic acidosis during high-dose midazolam therapy for refractory status epilepticus
Shalendra Singh, Ankur Khandelwal, Rashmi Datta, Ashutosh Kaushal, Gyaninder Pal SinghIndian Journal of Critical Care Medicine 2018 22(2):119-121 High-dose continuous midazolam therapy has been used successfully for control of refractory status epilepticus. However, normal anion gap (AG) metabolic acidosis, a deleterious complication of this therapy is underrecognized. Even though previously reported in an isolated case report in a pediatric patient, we observed similar complication in an adult patient. Stereotyped normal AG metabolic acidosis along with hypotension developed on two occasions during high-dose continuous m...
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Shalendra Singh Ankur Khandelwal Rashmi Datta Ashutosh Kaushal Gyaninder Pal Singh Source Type: research

The Fondaparinux paradox: Fondaparinux-related heparin-induced thrombocytopenia
Sonali Vadi, Vishal PeshattiwarIndian Journal of Critical Care Medicine 2018 22(2):116-118 Fondaparinux, a pentasaccharide administered for heparin-induced thrombocytopenia (HIT), can lead to the occurrence of thrombocytopenia. This patient underwent aortic stent graft placement for Salmonella paratyphi A-infected abdominal aortic aneurysm. Fondaparinux was administered for anticoagulation that led to a dramatic decline in his platelet counts. Investigations revealed HIT profile, PF4/heparin by particle gel immunoassay to be positive. Fondaparinux, a prescribed anticoagulant for HIT can paradoxically predispose to thrombo...
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Sonali Vadi Vishal Peshattiwar Source Type: research

Extracorporeal membrane oxygenation in drug overdose: A clinical case series
We report three patients with cardiovascular medication overdose presenting with profound cardiovascular instability refractory to medical therapy. Venoarterial extracorporeal membrane oxygenation support (VA ECMO) was initiated to provide hemodynamic support. Despite the occurrence of device-associated complications, the outcome was good and all patients survived. VA ECMO may be considered in patients with severe refractory shock due to cardiotoxic medication overdose. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: C Vignesh Madhan Kumar Ramesh Venkataraman Senthilkumar Rajagopal Nagarajan Ramakrishnan Babu K Abraham Source Type: research

Scrub typhus & #8211; A major cause of pediatric intensive care admission and multiple organ dysfunction syndrome: A single-center experience from India
Conclusion: Scrub typhus is an important cause of MODS in this part of the world, especially in fevers associated with features as identified and not responding to conventional antibiotics. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Prabahs Prasun Giri Joydeb Roy Agnisekhar Saha Source Type: research

Colistin-resistant Klebsiella pneumoniae in surgical polytrauma intensive care unit of level-1 trauma center: First case series from trauma patients in India
Conclusions: CRK is an emerging and challenging pathogen in polytrauma victims . There was an outbreak of CRK in our ICU that could be contained with infection control measures. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Richa Aggarwal Neha Rastogi Purva Mathur Kapil Dev Soni Subodh Kumar Amit Gupta Sushma Sagar Source Type: research

Immediate effects of acapella & #174; on dynamic lung compliance in mechanically ventilated patients with acute respiratory distress syndrome: A case series
Conclusion: Acapella® increased the dynamic compliance of lungs and sputum clearance in mechanically ventilated ARDS patients. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Priya Sharma V Prem Sakshee Jain Source Type: research

Serum estradiol level at intensive care unit admission and mortality in critically ill patients
Conclusions: The serum estradiol level is elevated in critically ill patients, regardless of gender, especially in those who die. It has good discriminative capacity to predict mortality, and it is an independent risk factor for death in this group of patients. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Luis Alejandro Sanchez.Hurtado Rolando Lugo-Cob Brigette C Tejeda-Huezo Alejandro Esquivel-Ch & #225;vez Abraham A Cano-Oviedo Sergio Zamora-Varela Saira S Gomez-Flores Perla Arvizu-Tachiquin Jos & #233; A Baltazar-Torres Source Type: research

Relationship of serum procalcitonin, c-reactive protein, and lactic acid to organ failure and outcome in critically ill pediatric population
Conclusions: This study found that in comparison to PCT and CRP, high plasma lactic acid levels are associated with the development of all-cause MODS and worse outcome in critically ill children admitted in PICU. Prediction of prognosis based on the lactic acid alone may contribute to improve patient management, but further studies are required to endorse our findings. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Imran Siddiqui Lena Jafri Qalab Abbas Ahmed Raheem Anwar Ul Haque Source Type: research

Comparative study between noninvasive continuous positive airway pressure and hot humidified high-flow nasal cannulae as a mode of respiratory support in infants with acute bronchiolitis in pediatric intensive care unit of a Tertiary Care Hospital
Conclusion: HHHFNC is an emerging alternative to nCPAP in the management of infants with acute bronchiolitis. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Mihir Sarkar Rajasree Sinha Satyabrata Roychowdhoury Sobhanman Mukhopadhyay Pramit Ghosh Kalpana Dutta Shibarjun Ghosh Source Type: research

Diagnostic value of procalcitonin in predicting bacteremia in intensive care unit
Conclusions: PCT may be an effective biomarker for diagnosing sepsis and predicting disease severity and mortality. There is a need for further well-designed studies to confirm the diagnostic and prognostic value of PCT in septic patients in critical care. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 19, 2018 Category: Intensive Care Authors: Tuna Demirdal Pinar Sen Salih Atakan Nemli Source Type: research