The Role of Nutritional Support in Malnourished Patients With Lung Cancer
This review aimed to aggregate and describe the available data about clinical nutrition in lung cancer and the role of the dietitian in multidisciplinary patient care. Scientific literature was searched in order to summarize key aspects related to clinical nutrition in lung cancer. This information can be used to arrange a proper nutritional therapy that can enhance patient treatment responses, prevent side-effects, shorten recovery time, improve prognosis and increase quality of life. An anti-inflammatory diet rich in antioxidants, immunomodulatory compounds, dietary fibre and an appropriate intake of protein can reduce t...
Source: In Vivo - January 5, 2021 Category: Research Authors: KASPRZYK, A., BILMIN, K., CHMIELEWSKA-IGNATOWICZ, T., PAWLIKOWSKI, J., RELIGIONI, U., MERKS, P. Tags: Reviews Source Type: research
Aortitis - An Interdisciplinary Challenge
The term ‘aortitis’ comprises a heterogeneous spectrum of diseases, with varied etiology and clinical presentations, whose common characteristic is the inflammation of the aortic wall. Since aortitis can mimic almost all common cardiovascular disorders, its clinical recognition remains a challenge. Some cases of aortitis remain undetected for a long time and may be diagnosed after severe life-threatening complications have already arisen. The diagnosis of aortitis is based on the presence of homogeneous circumferential thickening of the aortic wall detected on aortic imaging, or typical histological features in...
Source: In Vivo - January 5, 2021 Category: Research Authors: SHCHETYSNKA-MARINOVA, T., AMENDT, K., SADICK, M., KEESE, M., SIGL, M. Tags: Reviews Source Type: research
Circulating Tumor Cells, Circulating Tumor DNA and Other Blood-based Prognostic Scores in Pancreatic Ductal Adenocarcinoma - Mini-Review
Pancreatic ductal adenocarcinoma represents a disease with increasing incidence. Its prognosis is the worst among all malignancies despite the aggressive combined multimodal treatment across all stages. In metastatic disease, median survival is approximatelly one year. The mainstay of treatment is chemotherapy (neo/adjuvant, palliative) and in selected subgroups of patients even radiotherapy. Nevertheless, nowadays there are very few prognostic and/or predictive biomarkers available that can be used to identify and better stratify patients based on risk to tailored treatment. Potentially, promising areas of research are ci...
Source: In Vivo - January 5, 2021 Category: Research Authors: LIBERKO, M., KOLOSTOVA, K., SZABO, A., GURLICH, R., OLIVERIUS, M., SOUMAROVA, R. Tags: Reviews Source Type: research
Sensitivity, Specificity and the Diagnostic Accuracy of PET/CT for Axillary Staging in Patients With Stage I-III Cancer: A Systematic Review of The Literature
Conclusion: 18FDG-PET/CT has a low sensitivity but high specificity for ALN disease. Therefore, ultrasound-guided biopsy could be considered in a positive CT/PET. Modest accuracy prohibits the use of 18FDG-PET/CT alone in axillary staging. Prospective research using standardised protocols and quantitative cut-off points is warranted. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: KASEM, J., WAZIR, U., MOKBEL, K. Tags: Reviews Source Type: research
Therapeutic Application of Mesenchymal Stem Cells for Cochlear Regeneration
Hearing loss is one of the major worldwide health problems that seriously affects human social and cognitive development. In the auditory system, three components outer ear, middle ear and inner ear are essential for the hearing mechanism. In the inner ear, sensory hair cells and ganglion neuronal cells are the essential supporters for hearing mechanism. Damage to these cells can be caused by long-term exposure of excessive noise, ototoxic drugs (aminoglycosides), ear tumors, infections, heredity and aging. Since mammalian cochlear hair cells do not regenerate naturally, some therapeutic interventions may be required to re...
Source: In Vivo - January 5, 2021 Category: Research Authors: MAHARAJAN, N., CHO, G. W., JANG, C. H. Tags: Reviews Source Type: research
Suturing Skills for Medical Students: A Systematic Review
Conclusion: To our knowledge this is the first systematic review investigating teaching interventions used to teach suturing skills in medical students. After extraction of individual positive teaching outcomes and utilising widely known learning theories and principles, we devised a comprehensive framework for more efficient and cost-effective teaching of suturing skills to medical students in the future. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: EMMANUEL, T., NICOLAIDES, M., THEODOULOU, I., YOONG, W., LYMPEROPOULOS, N., SIDERIS, M. Tags: Reviews Source Type: research
Index
(Source: In Vivo)
Source: In Vivo - November 4, 2020 Category: Research Tags: Index Source Type: research
A Nasopharyngeal Carcinoma Patient With COVID-19 Infection After Immunotherapy: A Case Report and Literature Review
Conclusion: The patient with nasopharyngeal carcinoma in this case developed severe COVID-19 after receiving immunotherapy. For patients treated with immune checkpoint inhibitors (ICIs) in epidemic areas, the safety of ICIs in cancer patients infected with SARS-CoV-2 should be considered. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: ZHAI, M., ZHANG, S. Tags: Articles on Covid-19 Source Type: research
Tracheostomy in Patients With COVID-19: A Single-center Experience
Conclusion: Our experience suggests that bedside percutaneous tracheostomy may be a useful option in patients with COVID-19. In cases where percutaneous tracheostomy is anticipated to be difficult, open tracheostomy using a negative pressure closure may be useful in preventing aerosolization and reducing the risk of infection of healthcare workers. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: OBATA, K., MIYATA, R., YAMAMOTO, K., BYN-YA, N., KASAI, T., INOUE, H., NARIMATSU, E., TAKANO, K. Tags: Articles on Covid-19 Source Type: research
Chest Computed Tomography Scoring in Patients With Novel Coronavirus-infected Pneumonia: Correlation With Clinical and Laboratory Features and Disease Outcome
Conclusion: In NCIP patients, two different radiological scores correlated with each other and with several clinical, laboratory features, and the CALL score. The quantitative score was a better independent predictor of the composite adverse outcome than the semiquantitative score. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: PUGLIESE, L., SBORDONE, F. P., GRIMALDI, F., RICCI, F., DI TOSTO, F., SPIRITIGLIOZZI, L., DI DONNA, C., PRESICCE, M., DE STASIO, V., BENELLI, L., D'ERRICO, F., PASQUALETTO, M., LEGRAMANTE, J. M., MATERAZZO, M., PELLICCIARO, M., BUONOMO, O. C., VANNI, G., Tags: Articles on Covid-19 Source Type: research
Radiotherapy in the COVID-19 Pandemic Era
Conclusion: We were able to treat all patients referred to our hospital and we were able to reduce risk of infection for both our patients and healthcare staff, guaranteeing continuum of care for our oncological patients. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: GONNELLI, A., MONTRONE, S., COCUZZA, P., URSINO, S., MANFREDI, B., MATTIONI, R., COCCIA, N., FUENTES, T., CALISTRI, E., PASQUALETTI, F., PAIAR, F. Tags: Articles on Covid-19 Source Type: research
Classical Drug Digitoxin Inhibits Influenza Cytokine Storm, With Implications for Covid-19 Therapy
Conclusion: Since cytokine storm is a host response, we suggest that digitoxin may have a therapeutic potential not only for influenza and but also for coronavirus infections. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: POLLARD, B. S., BLANCOl, J. C., POLLARD, J. R. Tags: Articles on Covid-19 Source Type: research
Clinical Prognostic Factors for Local Control and Survival After Irradiation of Grade II Gliomas
Conclusion: Independent predictors of local control and survival were identified that can contribute to better treatment personalization. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: WITTELER, J., SCHILD, S. E., RADES, D. Tags: Clinical Studies Source Type: research
De-escalated Therapy Omitting Anthracyclines for Stage I HER2-positive Breast Cancer: A Retrospective Observational Study
Conclusion: In a real-world setting, de-escalated therapy without anthracyclines demonstrated excellent outcomes similar to the standard therapy containing anthracyclines as well as lower adverse events. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: NAKAMOTO, S., IKEDA, M., KUBO, S., YAMAMOTO, M., YAMASHITA, T. Tags: Clinical Studies Source Type: research
A Novel Systemic Inflammatory Score Combined With Immunoinflammatory Markers Accurately Reflects Prognosis in Patients With Esophageal Cancer
Conclusion: SIS was a superior predictor of prognosis compared with existing immunoinflammatory markers and closely reflected the fluctuation of peripheral inflammatory cytokines in patients with EC. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: SUZUKI, T., ISHIBASHI, Y., TSUJIMOTO, H., NOMURA, S., KOUZU, K., ITAZAKI, Y., SUGIHARA, T., HARADA, M., ITO, N., SUGASAWA, H., KISHI, Y., UENO, H. Tags: Clinical Studies Source Type: research
