Interval Vibration Reduces Orthodontic Pain Via a Mechanism Involving Down-regulation of TRPV1 and CGRP
Conclusion: Vibration represents a promising mechanical approach to reduce orthodontic pain. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: THAMMANICHANON, P., KAEWPITAK, A., BINLATEH, T., LEETHANAKUL, C. Tags: Experimental Studies Source Type: research
Huaier Extract Induces Apoptosis in Hepatoblastoma Cells Via the MEK/ERK Signaling Pathway
Conclusion: Huaier extract inhibits proliferation, and induces cell apoptosis and cell cycle arrest via the MEK-ERK pathway in hepatoblastoma cells. Huaier extract may act as a complementary agent for treating hepatoblastoma. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: XU, D.-Q., YUAN, X.-J., HIRAYAMA, M., TOYODA, H. Tags: Experimental Studies Source Type: research
Monte Carlo Modeling of the Agility MLC for IMRT and VMAT Calculations
Conclusion: Our findings demonstrate the accuracy of the MC model using an adapted BEAMnrc component module for the Agility MLC. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: OHIRA, S., TAKEGAWA, H., MIYAZAKI, M., KOIZUMI, M., TESHIMA, T. Tags: Experimental Studies Source Type: research
Expansion of Human Dental Pulp Cells In Vitro Under Different Cryopreservation Conditions
Conclusion: Five percent DMSO may be the most optimal condition for tissue storage to preserve stem cells in situ. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: YAN, M., NADA, O. A., KLUWE, L., GOSAU, M., SMEETS, R., FRIEDRICH, R. E. Tags: Experimental Studies Source Type: research
Salivary NUS1 and RCN1 Levels as Biomarkers for Oral Squamous Cell Carcinoma Diagnosis
Conclusion: A combination of NUS1 and RCN1 accurately distinguished patients from controls, and this combination can be implemented as a screening test for OSCC. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: UEDA, S., HASHIMOTO, K., MIYABE, S., HASEGAWA, S., GOTO, M., SHIMIZU, D., OH-IWA, I., SHIMOZATO, K., NAGAO, T., NOMOTO, S. Tags: Experimental Studies Source Type: research
Oral Administration of Geranylgeraniol Rescues Denervation-induced Muscle Atrophy via Suppression of Atrogin-1
Conclusion: Intraoral administration of GGOH rescues denervation-induced muscle atrophy via suppression of Atrogin-1. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: MIYAWAKI, A., ROJASAWASTHIEN, T., HITOMI, S., AOKI, Y., URATA, M., INOUE, A., MATSUBARA, T., MORIKAWA, K., HABU, M., TOMINAGA, K., KOKABU, S. Tags: Experimental Studies Source Type: research
Effect of 7,12-Dimethylbenz({alpha})anthracene on the Expression of miR-330, miR-29a, miR-9-1, miR-9-3 and the mTORC1 Gene in CBA/Ca Mice
Conclusion: miR-9-3 and mTORC1 expression in female mice were found to be the most suitable biomarkers for rapid identification of possible carcinogenic effects. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: TOMESZ, A., SZABO, L., MOLNAR, R., DEUTSCH, A., DARAGO, R., MATHE, D., BUDAN, F., GHODRATOLLAH, N., VARJAS, T., NEMETH, B., KISS, I. Tags: Experimental Studies Source Type: research
Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study Ex Vivo
Conclusion: Defined areas of the tooth root may be treated using the PIRL. For clinical translation, it would be necessary to improve beam delivery to facilitate beam steering for the intended oral application (e.g. by using a fiber) and identify optimal repetition rates/scan speeds combined with cooling techniques to minimize accumulated heat within ablation cavities. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: FRIEDRICH, R. E., QUADE, M., JOWETT, N., KROETZ, P., AMLING, M., KOHLRUSCH, F. K., ZUSTIN, J., GOSAU, M., SCHLUTER, H., MILLER, R. J. D. Tags: Experimental Studies Source Type: research
Deep Sequencing Identified Dysregulated Circulating MicroRNAs in Late Onset Preeclampsia
Conclusion: miR-23b-5p and miR-99b-5p are possibly implicated in the pathogenic mechanisms leading to the induction of LOPE and may serve as candidate non-invasive biomarkers for early prediction and prevention. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: MAVRELI, D., LYKOUDI, A., LAMBROU, G., PAPAIOANNOU, G., VRACHNIS, N., KALANTARIDOU, S., PAPANTONIOU, N., KOLIALEXI, A. Tags: Experimental Studies Source Type: research
An Improved Encapsulation Method for Cryopreserving Hepatocytes for Functional Transplantation Using a Thermo-reversible Gelation Polymer
Conclusion: We demonstrated a cryopreservation method of rat hepatocyte encapsulation using a TGP gel in the hydrogel state which subsequently allowed successful transplantation of unencapsulated hepatocytes in a sol state TGP gel at low temperature. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: YAMADA, K., AOKI, T., ENAMI, Y., TASHIRO, Y., ZEHAOU, Z., KOIZUMI, T., KUSANO, T., MATSUDA, K., WADA, Y., SHIBATA, H., TOMIOKA, K., SIRIRATSIVAWONG, K., HOFFMAN, R. M., MURAKAMI, M. Tags: Experimental Studies Source Type: research
Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models
Conclusion: Anti-TAG-72 monoclonal antibody conjugated to IRDye800 provides distinct and bright labeling of colorectal tumors in orthotopic nude-mouse models of liver metastasis. TAG-72 may be a useful target for intra-operative imaging of colorectal cancer liver metastasis in the clinic. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: HOLLANDSWORTH, H. M., NISHINO, H., TURNER, M., AMIRFAKHRI, S., FILEMONI, F., HOFFMAN, R. M., YAZAKI, P. J., BOUVET, M. Tags: Experimental Studies Source Type: research
Hepatocellular Carcinoma-associated microRNAs Induced by Hepatoma-derived Growth Factor Stimulation
Conclusion: We identified two candidate microRNAs whose expression increased in response to HDGF stimulation. Both these molecules were associated with a poor prognosis of HCC patients. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: ENOMOTO, H., NAKAMURA, H., NISHIKAWA, H., NISHIMURA, T., IWATA, Y., NISHIGUCHI, S., IIJIMA, H. Tags: Experimental Studies Source Type: research
In Vitro and In Vivo Biocompatibility Analysis of a New Transparent Collagen-based Wound Membrane for Tissue Regeneration in Different Clinical Indications
Conclusion: The newly transparent collagen membrane is fully biocompatible and is supporting safe clinical application in tissue repair and surgery. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: JUNG, O., RADENKOVIC, M., STOJANOVIĆ, S., LINDNER, C., BATINIC, M., GORKE, O., PISSAREK, J., PROHL, A., NAJMAN, S., BARBECK, M. Tags: Experimental Studies Source Type: research
Oral Methioninase Inhibits Recurrence in a PDOX Mouse Model of Aggressive Triple-negative Breast Cancer
Conclusion: o-rMETase is an effective adjuvant treatment for aggressive TNBC. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: LIM, H. I., HAMADA, K., YAMAMOTO, J., HAN, Q., TAN, Y., CHOI, H. J., NAM, S. J., BOUVET, M., HOFFMAN, R. M. Tags: Experimental Studies Source Type: research
Indocyanine Green Labels an Orthotopic Nude-Mouse Model of Very-Early Colon-Cancer Liver Metastases
Conclusion: Small CCLM can be clearly identified by ICG fluorescence in an orthotopic nude-mouse model. This model is translatable to the clinic for the detection of occult early CCLM. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: TASHIRO, Y., HOLLANDSWORTH, H. M., NISHINO, H., YAMAMOTO, J., AMIRFAKHRI, S., FILEMONI, F., SUGISAWA, N., AOKI, T., MURAKAMI, M., HOFFMAN, R. M., BOUVET, M. Tags: Experimental Studies Source Type: research
