I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model
Conclusion The data indicate that interference with beta-AR signalling has no long-term benefit in this severe MYBPC3-related cardiomyopathy mouse model. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 24, 2015 Category: Cardiology Source Type: research

Diagnostic accuracy of 64 slice multidetector coronary computed tomographic angiography in left ventricular systolic dysfunction
Conclusion Sixty-four slice multidetector CCTA is a very sensitive and fairly specific noninvasive diagnostic procedure for detecting coronary stenosis in patients with chest pain regardless of LV systolic function at presentation. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 24, 2015 Category: Cardiology Source Type: research

Distinct electrophysiological and mechanical beating phenotypes of long QT syndrome type 1-specific cardiomyocytes carrying different mutations
Publication date: 1 September 2015 Source:IJC Heart & Vasculature, Volume 8 Author(s): Anna L. Kiviaho , Antti Ahola , Kim Larsson , Kirsi Penttinen , Heikki Swan , Mari Pekkanen-Mattila , Henna Venäläinen , Kiti Paavola , Jari Hyttinen , Katriina Aalto-Setälä Background Long QT syndrome (LQTS) is associated with increased risk of ventricular arrhythmias and cardiac arrest. LQTS type 1 (LQT1), the most prevalent subtype of LQTS, is caused by defects of slow delayed rectifier potassium current (IKs) that lead to abnormal cardiac repolarization. Here we used pluripotent stem cell (iPSC)-technolo...
Source: IJC Heart and Vasculature - June 24, 2015 Category: Cardiology Source Type: research

Catheter-based intervention for pulmonary vein stenosis due to fibrosing mediastinitis: The mayo clinic experience
Conclusions We describe the largest reported case series of catheter-based intervention for PV stenosis in FM. Although catheter-based therapy improved hemodynamics, short-term vascular patency and patient symptoms, the rate of life-threatening complications, restenosis and mortality associated with these interventions was found to be high. Despite these associated risks, catheter-based intervention is the only palliative option available to improve quality of life in severely symptomatic patients with PV stenosis and FM. Patients with PV stenosis and FM (especially those with bilateral disease) have an overall poor progno...
Source: IJC Heart and Vasculature - June 18, 2015 Category: Cardiology Source Type: research

Expression of let-7 family microRNAs in skin correlates negatively with severity of pulmonary hypertension in patients with systemic scleroderma
Conclusions The results suggest that skin miRNA is a potentially useful marker for the presence and severity of PH in patients with SSc. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 18, 2015 Category: Cardiology Source Type: research

Changes in the reference lumen size of target lesions before and after coronary stent implantation: Evaluation with frequency domain optical coherence tomography
Conclusions When we select the stent size during OCT-guided PCI, we need to pay attention to the decrease in the luminal measurement of the reference sites, especially in lesions with tight stenosis. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 17, 2015 Category: Cardiology Source Type: research

An inspection of therapeutic hypothermia preceding coronary reperfusion in patients with a cardiogenic shock complicating anterior ST-segment elevation myocardial infarction
Conclusions The present study may imply a crucial possibility of clinical benefits of pre-PCI procedural therapeutic hypothermia in patients with a cardiogenic shock complicating anterior STEMI. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 17, 2015 Category: Cardiology Source Type: research

Olmesartan reverses not only vascular endothelial dysfunction but cardiac diastolic dysfunction in hypertensive patients with heart failure with preserved ejection fraction - ORION study -
Publication date: Available online 16 June 2015 Source:IJC Heart & Vasculature Author(s): Eiichiro Yamamoto , Keisuke Ohba , Yoshihiro Hirata , Takanori Tokitsu , Koichiro Fujisue , Koichi Sugamura , Koichi Kaikita , Seiji Hokimoto , Seigo Sugiyama , Hisao Ogawa (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 16, 2015 Category: Cardiology Source Type: research

Early use of beta blockers in patients with cocaine associated chest pain
Conclusions This study does not support the presence of an UAE in patients with continuing CICP and treated early with BB. There were no in-hospital cardiovascular complications in the group of patients who had an early dose of BB the while having CICP. Implications BB appeared safe when given early on admission to patients with CICP. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 14, 2015 Category: Cardiology Source Type: research

A review of the safety aspects of radio frequency ablation
Publication date: Available online 9 June 2015 Source:IJC Heart & Vasculature Author(s): Abhishek Bhaskaran , William Chik , Stuart Thomas Pramesh Kovoor , Aravinda Thiagalingam In light of recent reports showing high incidence of silent cerebral infarcts and organized atrial arrhythmias following radiofrequency (RF) atrial fibrillation (AF) ablation, a review of its safety aspects is timely. Serious complications do occur during Supraventricular tachycardia (SVT) ablations and knowledge of their incidence is important when deciding whether to proceed with ablation. Evidence is emerging for the probable role of p...
Source: IJC Heart and Vasculature - June 9, 2015 Category: Cardiology Source Type: research

Intracoronary administration of nicorandil during primary percutaneous coronary intervention: Impact on restoration of regional myocardial perfusion in reperfused myocardium during the subacute phase of myocardial infarction
Conclusions 15O-labeled water PET was feasible for segmental analysis of MBF during the subacute phase of STEMI. It revealed that intracoronary administration of nicorandil to STEMI patients who underwent PCI prevented MVR elevation and thus restored MBF in the reperfused segments to a level similar to that in the normal segments. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 6, 2015 Category: Cardiology Source Type: research

Incidence of thromboembolism following detection by trans-oesophageal echocardiography of left atrial thrombus
Conclusion This is the only study to date that has looked at the incidence of ischemic stroke following a confirmed LAA thrombus, LA thrombus or pre-thrombus state. This single centre study found low stroke rates over a six month follow-up period in patients with a confirmed LAA thrombus, LA thrombus or pre-thrombus state and optimization of OAC. Larger studies would be required to confirm these findings. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - June 2, 2015 Category: Cardiology Source Type: research

I-1-deficiency impacts negatively on survival in a cardiomyopathy mouse model
Conclusion The data indicate that interference with beta-AR signalling has no long-term benefit in this severe MYBPC3-related cardiomyopathy mouse model. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 30, 2015 Category: Cardiology Source Type: research

Controlled Heart Rate and Blood Pressure Reduce the Life Threatening Aortic Events and Increase Survival in Patients with Type B Aortic Dissection: A Single Center Experience
Publication date: Available online 26 May 2015 Source:IJC Heart & Vasculature Author(s): Karmacharya Ujit Kumar , Qian Zhao , Xue Bai , Ang Li , Pandit Anjali , Haibin Yu , Wei Zhu , Ting Zou , Yingtong Ma , Xiang Ma (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 27, 2015 Category: Cardiology Source Type: research

Assessment of speckle tracking strain predictive value for myocardial fibrosis in subjects with Chagas disease
Publication date: Available online 25 May 2015 Source:IJC Heart & Vasculature Author(s): Carolina Thé Macedo , Ticiana Ferreira Larocca , Márcia Noya-Rabelo , Luís Claudio Lemos Correia , Moisés Imbassahí Moreira , Alessandra Caldas , Jorge Andion Torreão , Bruno Solano de Freitas Souza , Ricardo Ribeiro dos Santos , Milena Botelho Pereira Soares (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 26, 2015 Category: Cardiology Source Type: research

A new circular mapping-guided approach for endoscopic laser balloon pulmonary vein isolation
Publication date: Available online 23 May 2015 Source:IJC Heart & Vasculature Author(s): Pim Gal , Jaap Jan J. Smit , Ahmet Adiyaman , Anand R. Ramdat Misier , Peter Paul H.M. Delnoy , Arif Elvan (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 24, 2015 Category: Cardiology Source Type: research

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content
Publication date: Available online 23 May 2015 Source:IJC Heart & Vasculature Author(s): Kristina Svennerholm , Pouria Rodsand , Urban Hellman , Marie Lundholm , Anders Waldenström , Björn Biber , Gunnar Ronquist , Michael Haney (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 24, 2015 Category: Cardiology Source Type: research

Ischemic Postconditioning of the Isolated Human Myocardium: Role of the applied protocol
Conclusions The present findings show that IPostC of the human myocardium may be influenced by the protocol used and also by the degree of the preceding ischemic injury. IPostC was beneficial in approximately 1/3 of the cases; however in the remaining cases it increased ischemic damage and, therefore, these results raise a word of caution on its broad clinical use. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 24, 2015 Category: Cardiology Source Type: research

Association of Estimated Central Blood Pressure Measured Non-invasively with Pulse Wave Velocity in Patients with Coronary Artery Disease
Publication date: Available online 22 May 2015 Source:IJC Heart & Vasculature Author(s): Daisuke Sueta , Eiichiro Yamamoto , Tomoko Tanaka , Yoshihiro Hirata , Kenji Sakamoto , Kenichi Tsujita , Sunao Kojima , Koichi Nishiyama , Koichi Kaikita , Seiji Hokimoto , Hideaki Jinnouchi , Hisao Ogawa (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 22, 2015 Category: Cardiology Source Type: research

WITHDRAWN: Near-infrared spectroscopy characterization of internal carotid artery restenosis after endarterectomy
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 22, 2015 Category: Cardiology Source Type: research

Transient global amnesia complicating dobutamine–atropine stress echocardiography
Publication date: 1 June 2015 Source:IJC Heart & Vasculature, Volume 7 Author(s): Vikram Agarwal , Pragya Ranjan , Abel Casso Dominguez , Jincy Thankachen (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 22, 2015 Category: Cardiology Source Type: research

Risk stratification using the CHA2DS2-VASc score in patients with coronary heart disease undergoing percutaneous coronary intervention; sub-analysis of SHINANO registry
Conclusions This study demonstrated that CHA2DS2-VASc score could provide prognostic information in CHD without known AF. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 22, 2015 Category: Cardiology Source Type: research

Chronic total occlusions — Current techniques and future directions
Publication date: 1 June 2015 Source:IJC Heart & Vasculature, Volume 7 Author(s): George Touma , David Ramsay , James Weaver Chronic total occlusions (CTOs) of coronary arteries represent a common and significant challenge to interventional cardiology. Medical therapy is often regarded as an adequate long term strategy in the management of these lesions with surgical intervention for refractory symptoms. Extensive collateralisation is used as a marker of distal coronary perfusion, further reinforcing non-invasive strategies. This together with relatively low percutaneous success rates outside of specialised centr...
Source: IJC Heart and Vasculature - May 22, 2015 Category: Cardiology Source Type: research

Accurate Monitoring of Intravascular Fluid Volume: A Novel Application of Intrathoracic Impedance Measures for the Guidance of Volume Reduction Therapy
Publication date: Available online 15 May 2015 Source:IJC Heart & Vasculature Author(s): Barbara A. Lara , Fujian Qu , E. Kevin Heist , Behzad B. Pavri , Adrian B. Van Bakel , John M. Herre , Philip F. Binkley (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 16, 2015 Category: Cardiology Source Type: research

A pulmonary vein thrombus in a patient with autonomic nervous dysfunction
Publication date: Available online 8 May 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi Ischemic stroke is a serious clinical problem, and preventing ischemic stroke is an important clinical target. Left atrial thrombus is a known cause of ischemic stroke. In 2015, I reported that nearly all left atrial thrombi result from a pulmonary vein thrombus (PVT), indicating that PVT is associated with ischemic stroke. However, the relationship between PVT and autonomic nervous function is unknown. Although PVT is believed to be rare, since 2012, I have reported several cases of PVT in elderly patients w...
Source: IJC Heart and Vasculature - May 9, 2015 Category: Cardiology Source Type: research

Histology of Human Right Atrial Tissue in Patients with High-Risk Obstructive Sleep Apnea: More Work Needed
Publication date: Available online 7 May 2015 Source:IJC Heart & Vasculature Author(s): Erik van Oosten , Adrian Baranchuk (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - May 8, 2015 Category: Cardiology Source Type: research

A swinging left atrial thrombus connecting to a right lower pulmonary vein thrombus
Publication date: Available online 28 April 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 28, 2015 Category: Cardiology Source Type: research

Optimum duration of dual antiplatelet treatment could be decided using 64-MDCT: A new hint to treating patients with stents
Publication date: Available online 27 April 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 27, 2015 Category: Cardiology Source Type: research

Distinct electrophysiological and mechanical beating phenotypes of Long QT syndrome type 1 -specific cardiomyocytes carrying different mutations
Conclusions Both LQT1-CM-types showed prolonged repolarization, but only those with G589D presented early after-depolarizations at baseline. Increased amount of abnormal Ca2+ transients were detected in both types of LQT1-CMs. Surprisingly, also the mechanical beating behavior demonstrated clear abnormalities and additionally the abnormalities were different with the two mutations: prolonged contraction was seen in G589D-CMs while impaired relaxation was observed in ivs7-2A>G-CMs. The CMs carrying two different LQT1 specific mutations (G589D or ivs7-2A>G) presented clear differences in their electrical proper...
Source: IJC Heart and Vasculature - April 26, 2015 Category: Cardiology Source Type: research

The appearance of a small thrombus in the pulmonary vein indicates the existence of a smaller pulmonary vein
Publication date: Available online 22 April 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi Left atrial appendage thrombi and left atrial thrombi are known to cause ischemic stroke. Pulmonary vein thrombosis manifests with either atypical or subtle symptoms and is believed to be rare. However, this condition is life threatening and necessitates the development of tools and protocols to recognize and diagnose the presence of thrombi. Angiography via 64-slice multidetector CT (64-MDCT) is a procedure used to assess coronary artery plaques and identify the presence of LAA thrombi. Additionally, sinc...
Source: IJC Heart and Vasculature - April 23, 2015 Category: Cardiology Source Type: research

Transcatheter aortic valve implantation in patients with pre-existing chronic kidney disease
Conclusion TAVI is a safe, acceptable treatment for patients with pre-existing CKD, however caution must be exercised, particularly in patients with pre-existing diabetes mellitus and elevated pre-operative serum creatinine levels as this confers a greater risk of AKI development, which is associated with increased short-term post-operative mortality. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 23, 2015 Category: Cardiology Source Type: research

Diagnostic accuracy of 64 slice multi-detector coronary computed tomographic angiography in left ventricular systolic dysfunction
Conclusion 64-multidetector CCTA is a very sensitive and fairly specific noninvasive diagnostic procedure for detecting coronary stenosis in patients with chest pain regardless of LV systolic function at presentation. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 22, 2015 Category: Cardiology Source Type: research

Pulmonary vein orientation assessment: Is it necessary in patients undergoing contact force sensing guided radiofrequency catheter ablation of atrial fibrillation
Conclusions This study shows that in patients undergoing PVI with the CFC ablation system, PV orientation does not affect CF and is not associated with AF free survival. PV orientation assessment does not appear to be necessary in patients undergoing CFC PVI. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 18, 2015 Category: Cardiology Source Type: research

Hypertension should be ruled out in patients with hyperdynamic left ventricle on radionuclide myocardial perfusion imaging, diastolic dysfunction and dyspnea on exertion
Publication date: Available online 9 April 2015 Source:IJC Heart & Vasculature Author(s): Fatih Yalçin , Thomas Schindler , Theodore P. Abraham (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 9, 2015 Category: Cardiology Source Type: research

Text-messaging program improves outcomes in outpatient cardiovascular rehabilitation
Conclusions Patients enrolled in OP-CR who participated in a text-messaging program were younger, attended significantly more sessions and were significantly more likely to complete the program. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 8, 2015 Category: Cardiology Source Type: research

Pulmonary vein thromboses might cause and promote cardiovascular disease via genetic modulation by occluding microvessels in elderly patients
Publication date: Available online 8 April 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 8, 2015 Category: Cardiology Source Type: research

Could early septal involvement in the remodeling process be related to the advance hypertensive heart disease?
Conclusions LV diastolic dysfunction becomes more severe in septal wall than lateral wall in hypertensive LVH. Septal myocardial performance is more dominantly affected by hypertension possibly due to earlier septal involvement in disease course. Septal MPI is correlated moderately with septal wall thickness. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 8, 2015 Category: Cardiology Source Type: research

Left ventricular ejection fraction is determined by both global myocardial strain and wall thickness
Conclusion The findings of this study explain the coexistence of reduced global myocardial strain and normal ejection fraction seen in clinical observational studies. Our understanding of the pathophysiological processes in heart failure and associated conditions is substantially enhanced. These results provide a much better insight into the biophysical inter-relationship between myocardial strain and ejection fraction. This improved understanding provides an essential foundation for the design and interpretation of future clinical mechanistic and prognostic studies. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 6, 2015 Category: Cardiology Source Type: research

Relative Diagnostic, Prognostic and Economic value of Stress Echocardiography versus Exercise Electrocardiography as Initial Investigation for the detection of Coronary Artery Disease in Patients with New Onset Suspected Angina
Conclusions SE is superior to ExECG for prediction of CAD and is cost-beneficial when used as initial test in patients with no history of CAD presenting with suspected angina. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 6, 2015 Category: Cardiology Source Type: research

Implementation of 64-MDCT assesses that short-term warfarin therapy can dissolve a completely occluding small thrombus: a new clue to treat atrial fibrillation
Publication date: Available online 2 April 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - April 2, 2015 Category: Cardiology Source Type: research

Transient Global Amnesia Complicating Dobutamine-Atropine Stress Echocardiography
Publication date: Available online 26 March 2015 Source:IJC Heart & Vasculature Author(s): Vikram Agarwal , Pragya Ranjan , Abel Casso Dominguez , Jincy Thankachen (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 27, 2015 Category: Cardiology Source Type: research

The independent association between altered renal arterial resistance and loop diuretic dose in chronic heart failure outpatients
Conclusions RRI is independently associated with high dose loop diuretics and their increase during a mid-term follow-up thus suggesting its usefulness in detecting an altered diuretic response in CHF outpatients. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 26, 2015 Category: Cardiology Source Type: research

Poor R-wave Progression and Myocardial Infarct Size after Anterior Myocardial Infarction in the Coronary Intervention Era
Conclusion Our data suggested that residual R-wave during the follow-up period reflected myocardial infarct size and left ventricular systolic function well in patients with prior anterior MI treated with coronary intervention. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 24, 2015 Category: Cardiology Source Type: research

No atrial fibrillation, no histologic findings but even no obstructive sleep apnea?
Publication date: Available online 13 March 2015 Source:IJC Heart & Vasculature Author(s): Stefanie Keymel , Dong In Shin , Stephan Steiner (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 14, 2015 Category: Cardiology Source Type: research

Acute and spontaneous coronary thrombosis in non-culprit artery during percutaneous coronary intervention in myocardial infarction with ST-segment elevation: a “shocking” case
Publication date: Available online 11 March 2015 Source:IJC Heart & Vasculature Author(s): Dario Buccheri , Patrizia Carità , Michele Carella , Davide Piraino , Paola Rosa Chirco , Giuseppe Andolina (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 12, 2015 Category: Cardiology Source Type: research

Cumulative effects of common genetic variants on risk of sudden cardiac death
Conclusions A modest but significant effect on SCD risk was identified for a GRS composed of 14 previously associated SCD SNPs. While next generation sequencing methodology will continue to identify additional novel variants, these findings represent proof of concept for the additive effects of gene variants on SCD risk. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 8, 2015 Category: Cardiology Source Type: research

Medium term follow-up after percutaneous pulmonary valve replacement with the Melody® valve
Conclusion Adequate pre-stenting of the RVOT before PPVI nearly abolishes or delays stent fracture. Cusp function is well preserved in mid-term follow-up; endocarditis is a significant threat. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 6, 2015 Category: Cardiology Source Type: research

Mouse Models for the Study of Postnatal Cardiac Hypertrophy
Publication date: Available online 6 March 2015 Source:IJC Heart & Vasculature Author(s): A. Del Olmo-Turrubiarte , A. Calzada-Torres , G. Díaz-Rosas , I. Palma-Lara , R. Sánchez-Urbina , N.A. Balderrábano-Saucedo , H. González-Márquez , P. Garcia-Alonso , A. Contreras-Ramos The main objective of this study was to create a postnatal model for cardiac hypertrophy (CH), in order to explain the mechanisms that are present in childhood cardiac hypertrophy. Five days after implantation, intraperitoneal (IP) isoproterenol (ISO) was injected for 7 days to pregnant female mice. The Fetu...
Source: IJC Heart and Vasculature - March 6, 2015 Category: Cardiology Source Type: research

A long and narrow pulmonary vein thrombus attached to the wall of a pulmonary vein
Publication date: Available online 28 February 2015 Source:IJC Heart & Vasculature Author(s): Hidekazu Takeuchi Pulmonary vein thrombosis (PVT) is often not diagnosed because PVT has subtle symptoms and PVT is believed to be rare. The mechanism for the formation of PVT is unclear. In this case, I describe a small thrombus in a small branch of a pulmonary vein draining into a larger vein, the right lower pulmonary vein (RLPV). The patient was a 70-year-old male with angina pectoris, and he presented with chest pain. He had no symptoms of cerebral infarction. He previously had been treated with percutaneous coronar...
Source: IJC Heart and Vasculature - March 1, 2015 Category: Cardiology Source Type: research

Novel Linkage of LMNA Single nucleotide polymorphism with Dilated Cardiomyopathy in an Indian case study
Conclusion Most of these SNPs in LMNA were previously reported to be involved in various disorders other than DCM. We conclude that, variation in LMNA is one of major underlying genetic cause for the pathogenesis of DCM, as observed in few Indian populations. (Source: IJC Heart and Vasculature)
Source: IJC Heart and Vasculature - March 1, 2015 Category: Cardiology Source Type: research