Lower NKG2D expression in hepatic natural killer cells predicts poorer prognosis for chronic hepatitis B patients with cirrhosis
CONCLUSIONS: Lower NKG2D expression in intra-hepatic NK cells may be predictive of poorer prognosis of CHB patients with cirrhosis.PMID:38493049 | DOI:10.1016/j.humimm.2024.110775 (Source: Human Immunology)
Source: Human Immunology - March 16, 2024 Category: Allergy & Immunology Authors: Yangqing Ma Dabing Ping Kai Huang Yanyan Tao Yuan Peng Xin Sun Chenghai Liu Source Type: research
Clinical outcomes of intestinal transplant recipients receiving maintenance basiliximab, sublingual tacrolimus and prednisone: A case series
CONCLUSION: The combination of monthly basiliximab, sublingual tacrolimus, and prednisone is an effective novel maintenance immunosuppression in intestinal transplantation. A larger and more extended study duration would be necessary to thoroughly assess the safety and sustained benefits of the novel maintenance immunosuppression regimen.PMID:38480040 | DOI:10.1016/j.humimm.2024.110787 (Source: Human Immunology)
Source: Human Immunology - March 13, 2024 Category: Allergy & Immunology Authors: Pierpaolo Di Cocco Alessandro Martinino Giulia Bencini Rachel Christensen Benito Valdepenas Egor Petrochenkov Stepan Akshelyan Jorge Almario-Alvarez Mario Spaggiari Ivo Tzvetanov Enrico Benedetti Source Type: research
Clinical outcomes of intestinal transplant recipients receiving maintenance basiliximab, sublingual tacrolimus and prednisone: A case series
CONCLUSION: The combination of monthly basiliximab, sublingual tacrolimus, and prednisone is an effective novel maintenance immunosuppression in intestinal transplantation. A larger and more extended study duration would be necessary to thoroughly assess the safety and sustained benefits of the novel maintenance immunosuppression regimen.PMID:38480040 | DOI:10.1016/j.humimm.2024.110787 (Source: Human Immunology)
Source: Human Immunology - March 13, 2024 Category: Allergy & Immunology Authors: Pierpaolo Di Cocco Alessandro Martinino Giulia Bencini Rachel Christensen Benito Valdepenas Egor Petrochenkov Stepan Akshelyan Jorge Almario-Alvarez Mario Spaggiari Ivo Tzvetanov Enrico Benedetti Source Type: research
Clinical outcomes of intestinal transplant recipients receiving maintenance basiliximab, sublingual tacrolimus and prednisone: A case series
CONCLUSION: The combination of monthly basiliximab, sublingual tacrolimus, and prednisone is an effective novel maintenance immunosuppression in intestinal transplantation. A larger and more extended study duration would be necessary to thoroughly assess the safety and sustained benefits of the novel maintenance immunosuppression regimen.PMID:38480040 | DOI:10.1016/j.humimm.2024.110787 (Source: Human Immunology)
Source: Human Immunology - March 13, 2024 Category: Allergy & Immunology Authors: Pierpaolo Di Cocco Alessandro Martinino Giulia Bencini Rachel Christensen Benito Valdepenas Egor Petrochenkov Stepan Akshelyan Jorge Almario-Alvarez Mario Spaggiari Ivo Tzvetanov Enrico Benedetti Source Type: research
Identification of novel HLA alleles discovered in 2022-2023
Hum Immunol. 2024 Mar 8:110772. doi: 10.1016/j.humimm.2024.110772. Online ahead of print.ABSTRACTIn this paper, we describe 10 novel HLA alleles discovered, submitted and officially named in the calendar years 2022 through the end of 2023.PMID:38461131 | DOI:10.1016/j.humimm.2024.110772 (Source: Human Immunology)
Source: Human Immunology - March 9, 2024 Category: Allergy & Immunology Authors: Michael D Gautreaux Elaine F O'Shields Eric M Netherton Sharlie B Brown Jennie W Stewart Kimberly N Weavil Hannah L Soul é Hayley N Sapkota David F Kiger Source Type: research
Identification of novel HLA alleles discovered in 2022-2023
Hum Immunol. 2024 Mar 8:110772. doi: 10.1016/j.humimm.2024.110772. Online ahead of print.ABSTRACTIn this paper, we describe 10 novel HLA alleles discovered, submitted and officially named in the calendar years 2022 through the end of 2023.PMID:38461131 | DOI:10.1016/j.humimm.2024.110772 (Source: Human Immunology)
Source: Human Immunology - March 9, 2024 Category: Allergy & Immunology Authors: Michael D Gautreaux Elaine F O'Shields Eric M Netherton Sharlie B Brown Jennie W Stewart Kimberly N Weavil Hannah L Soul é Hayley N Sapkota David F Kiger Source Type: research
Identification of novel HLA alleles discovered in 2022-2023
Hum Immunol. 2024 Mar 8:110772. doi: 10.1016/j.humimm.2024.110772. Online ahead of print.ABSTRACTIn this paper, we describe 10 novel HLA alleles discovered, submitted and officially named in the calendar years 2022 through the end of 2023.PMID:38461131 | DOI:10.1016/j.humimm.2024.110772 (Source: Human Immunology)
Source: Human Immunology - March 9, 2024 Category: Allergy & Immunology Authors: Michael D Gautreaux Elaine F O'Shields Eric M Netherton Sharlie B Brown Jennie W Stewart Kimberly N Weavil Hannah L Soul é Hayley N Sapkota David F Kiger Source Type: research
Identification of novel HLA alleles discovered in 2022-2023
Hum Immunol. 2024 Mar 8:110772. doi: 10.1016/j.humimm.2024.110772. Online ahead of print.ABSTRACTIn this paper, we describe 10 novel HLA alleles discovered, submitted and officially named in the calendar years 2022 through the end of 2023.PMID:38461131 | DOI:10.1016/j.humimm.2024.110772 (Source: Human Immunology)
Source: Human Immunology - March 9, 2024 Category: Allergy & Immunology Authors: Michael D Gautreaux Elaine F O'Shields Eric M Netherton Sharlie B Brown Jennie W Stewart Kimberly N Weavil Hannah L Soul é Hayley N Sapkota David F Kiger Source Type: research
HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration
In this study, we sequenced eight HLA genes using Next Generation Sequencing (NGS) from 134 Waorani individuals and obtained up to four-field HLA allele resolution. Cluster and phylogenetic analysis show that the Waorani are genetically distant from other Ecuador populations, but instead show genetic affinities with the Puyanawa and Terena tribes from Brazil, as well as the Mixe tribe from Mexico. The identification of alleles common within the Waorani population, previously linked to specific health conditions, notably paves the way for future association analyses. This extensive study, employing Next-Generation Sequencin...
Source: Human Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Samantha Saenz Hinojosa Timothy Adrian Jinam Kazuyoshi Hosomichi Vanessa I Romero Source Type: research
HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration
In this study, we sequenced eight HLA genes using Next Generation Sequencing (NGS) from 134 Waorani individuals and obtained up to four-field HLA allele resolution. Cluster and phylogenetic analysis show that the Waorani are genetically distant from other Ecuador populations, but instead show genetic affinities with the Puyanawa and Terena tribes from Brazil, as well as the Mixe tribe from Mexico. The identification of alleles common within the Waorani population, previously linked to specific health conditions, notably paves the way for future association analyses. This extensive study, employing Next-Generation Sequencin...
Source: Human Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Samantha Saenz Hinojosa Timothy Adrian Jinam Kazuyoshi Hosomichi Vanessa I Romero Source Type: research
HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration
In this study, we sequenced eight HLA genes using Next Generation Sequencing (NGS) from 134 Waorani individuals and obtained up to four-field HLA allele resolution. Cluster and phylogenetic analysis show that the Waorani are genetically distant from other Ecuador populations, but instead show genetic affinities with the Puyanawa and Terena tribes from Brazil, as well as the Mixe tribe from Mexico. The identification of alleles common within the Waorani population, previously linked to specific health conditions, notably paves the way for future association analyses. This extensive study, employing Next-Generation Sequencin...
Source: Human Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Samantha Saenz Hinojosa Timothy Adrian Jinam Kazuyoshi Hosomichi Vanessa I Romero Source Type: research
HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration
In this study, we sequenced eight HLA genes using Next Generation Sequencing (NGS) from 134 Waorani individuals and obtained up to four-field HLA allele resolution. Cluster and phylogenetic analysis show that the Waorani are genetically distant from other Ecuador populations, but instead show genetic affinities with the Puyanawa and Terena tribes from Brazil, as well as the Mixe tribe from Mexico. The identification of alleles common within the Waorani population, previously linked to specific health conditions, notably paves the way for future association analyses. This extensive study, employing Next-Generation Sequencin...
Source: Human Immunology - March 5, 2024 Category: Allergy & Immunology Authors: Samantha Saenz Hinojosa Timothy Adrian Jinam Kazuyoshi Hosomichi Vanessa I Romero Source Type: research
Current approaches for risk assessment of intestinal transplant patients: A view from the histocompatibility laboratory
Hum Immunol. 2024 Mar 2:110768. doi: 10.1016/j.humimm.2024.110768. Online ahead of print.ABSTRACTDespite its recent decline in volumes, intestinal transplantation remains an important option for patients with irreversible intestinal failures. The long-term outcome of an intestinal transplant has stagnated. The major cause of graft loss is rejection, resulting from mismatches in human leukocyte antigens (HLA) and the presence of antibodies to mismatched donor-specific HLA antigens (DSA). Literature has reported that DSAs, either preformed before transplantation or developed de novo after transplantation, are harmful to inte...
Source: Human Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Qingyong Xu Adriana Zeevi Armando Ganoza Ruy J Cruz George V Mazariegos Source Type: research
Investigating viral and autoimmune T cell responses associated with post-acute sequelae of COVID-19
Hum Immunol. 2024 Mar 2:110770. doi: 10.1016/j.humimm.2024.110770. Online ahead of print.ABSTRACTPost-acute sequelae of COVID-19 (PASC), or Long COVID, is a chronic condition following acute SARS-CoV-2 infection. Symptoms include exertion fatigue, respiratory issues, myalgia, and neurological manifestations such as 'brain fog,' posing concern for their debilitating nature and potential role in other neurological disorders. However, the underlying potential pathogenic mechanisms of the neurological complications of PASC is largely unknown. Herein, we investigated differences in antigen-specific T cell responses from the per...
Source: Human Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Gregory P Williams Esther Dawen Yu Kendra Shapiro Eric Wang Antoine Freuchet April Frazier Cecilia S Lindestam Arlehamn Alessandro Sette Ricardo da Silva Antunes Source Type: research
Current approaches for risk assessment of intestinal transplant patients: A view from the histocompatibility laboratory
Hum Immunol. 2024 Mar 2:110768. doi: 10.1016/j.humimm.2024.110768. Online ahead of print.ABSTRACTDespite its recent decline in volumes, intestinal transplantation remains an important option for patients with irreversible intestinal failures. The long-term outcome of an intestinal transplant has stagnated. The major cause of graft loss is rejection, resulting from mismatches in human leukocyte antigens (HLA) and the presence of antibodies to mismatched donor-specific HLA antigens (DSA). Literature has reported that DSAs, either preformed before transplantation or developed de novo after transplantation, are harmful to inte...
Source: Human Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Qingyong Xu Adriana Zeevi Armando Ganoza Ruy J Cruz George V Mazariegos Source Type: research
