Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation
CONCLUSIONS: Humoral immune responses to either KSAg alone or in combination with donor-specific anti-HLA antibodies are not associated with progression to CII at 1 and 2 years after kidney transplantation.PMID:37507262 | DOI:10.1016/j.humimm.2023.07.006 (Source: Human Immunology)
Source: Human Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Sumi Nair Ranjithkumar Ravichandran Raymond Heilman Andr és Jaramillo Matthew Buras Bruce Kaplan Yoshihiro Itabashi Daniel Ramon Katrin Hacke Byron Smith Thalachallour Mohanakumar Source Type: research

Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma
Hum Immunol. 2023 Jul 20:S0198-8859(23)00116-7. doi: 10.1016/j.humimm.2023.07.007. Online ahead of print.ABSTRACTInitially discovered in chronic viral infection and then extended to tumor, 'T-cell exhaustion' is a broad term describing the response of T cells to chronic antigen stimulation. By definition, whether T-cell exhaustion occurs in diffuse large B-cell lymphoma (DLBCL) remains largely unknown because little has been described. Here, the immune-suppressing checkpoint molecules involved in T-cell exhaustion, including PD-1, PD-L1, TIM-3 and TIGIT, whose expression levels were analyzed in DLBCL, were retrieved from t...
Source: Human Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Shutao Zheng Jiajia Ma Junna Li Xuelian Pang Mingfu Ma Zhiping Ma Wenli Cui Source Type: research

Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma
Hum Immunol. 2023 Jul 20:S0198-8859(23)00116-7. doi: 10.1016/j.humimm.2023.07.007. Online ahead of print.ABSTRACTInitially discovered in chronic viral infection and then extended to tumor, 'T-cell exhaustion' is a broad term describing the response of T cells to chronic antigen stimulation. By definition, whether T-cell exhaustion occurs in diffuse large B-cell lymphoma (DLBCL) remains largely unknown because little has been described. Here, the immune-suppressing checkpoint molecules involved in T-cell exhaustion, including PD-1, PD-L1, TIM-3 and TIGIT, whose expression levels were analyzed in DLBCL, were retrieved from t...
Source: Human Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Shutao Zheng Jiajia Ma Junna Li Xuelian Pang Mingfu Ma Zhiping Ma Wenli Cui Source Type: research

Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma
Hum Immunol. 2023 Jul 20:S0198-8859(23)00116-7. doi: 10.1016/j.humimm.2023.07.007. Online ahead of print.ABSTRACTInitially discovered in chronic viral infection and then extended to tumor, 'T-cell exhaustion' is a broad term describing the response of T cells to chronic antigen stimulation. By definition, whether T-cell exhaustion occurs in diffuse large B-cell lymphoma (DLBCL) remains largely unknown because little has been described. Here, the immune-suppressing checkpoint molecules involved in T-cell exhaustion, including PD-1, PD-L1, TIM-3 and TIGIT, whose expression levels were analyzed in DLBCL, were retrieved from t...
Source: Human Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Shutao Zheng Jiajia Ma Junna Li Xuelian Pang Mingfu Ma Zhiping Ma Wenli Cui Source Type: research

Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma
Hum Immunol. 2023 Jul 20:S0198-8859(23)00116-7. doi: 10.1016/j.humimm.2023.07.007. Online ahead of print.ABSTRACTInitially discovered in chronic viral infection and then extended to tumor, 'T-cell exhaustion' is a broad term describing the response of T cells to chronic antigen stimulation. By definition, whether T-cell exhaustion occurs in diffuse large B-cell lymphoma (DLBCL) remains largely unknown because little has been described. Here, the immune-suppressing checkpoint molecules involved in T-cell exhaustion, including PD-1, PD-L1, TIM-3 and TIGIT, whose expression levels were analyzed in DLBCL, were retrieved from t...
Source: Human Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Shutao Zheng Jiajia Ma Junna Li Xuelian Pang Mingfu Ma Zhiping Ma Wenli Cui Source Type: research

Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma
Hum Immunol. 2023 Jul 20:S0198-8859(23)00116-7. doi: 10.1016/j.humimm.2023.07.007. Online ahead of print.ABSTRACTInitially discovered in chronic viral infection and then extended to tumor, 'T-cell exhaustion' is a broad term describing the response of T cells to chronic antigen stimulation. By definition, whether T-cell exhaustion occurs in diffuse large B-cell lymphoma (DLBCL) remains largely unknown because little has been described. Here, the immune-suppressing checkpoint molecules involved in T-cell exhaustion, including PD-1, PD-L1, TIM-3 and TIGIT, whose expression levels were analyzed in DLBCL, were retrieved from t...
Source: Human Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Shutao Zheng Jiajia Ma Junna Li Xuelian Pang Mingfu Ma Zhiping Ma Wenli Cui Source Type: research

Influence of interleukin-8 polymorphism on endometriosis-related pelvic pain
Hum Immunol. 2023 Jul 17:S0198-8859(23)00113-1. doi: 10.1016/j.humimm.2023.07.004. Online ahead of print.ABSTRACTEndometriosis presents a pro-inflammatory microenvironment influenced by cytokines, such as interleukin (IL)-8, which expression may be influenced by genetic polymorphisms. Therefore, we aimed to investigate the role of interleukin (IL)-8 rs4073 polymorphism in endometriosis' development and its related symptoms. A case-control study was conducted with 207 women with endometriosis and 193 healthy controls. Polymorphism was genotyped using a TaqMan validated assay. Associations were evaluated by binary logistic r...
Source: Human Immunology - July 19, 2023 Category: Allergy & Immunology Authors: J éssica Vilarinho Cardoso Daniel Escorsim Machado Mayara Calixto da Silva Matheus Pereira de Mello Plinio Tostes Berardo Rui Medeiros Jamila Alessandra Perini Source Type: research

Influence of interleukin-8 polymorphism on endometriosis-related pelvic pain
Hum Immunol. 2023 Jul 17:S0198-8859(23)00113-1. doi: 10.1016/j.humimm.2023.07.004. Online ahead of print.ABSTRACTEndometriosis presents a pro-inflammatory microenvironment influenced by cytokines, such as interleukin (IL)-8, which expression may be influenced by genetic polymorphisms. Therefore, we aimed to investigate the role of interleukin (IL)-8 rs4073 polymorphism in endometriosis' development and its related symptoms. A case-control study was conducted with 207 women with endometriosis and 193 healthy controls. Polymorphism was genotyped using a TaqMan validated assay. Associations were evaluated by binary logistic r...
Source: Human Immunology - July 19, 2023 Category: Allergy & Immunology Authors: J éssica Vilarinho Cardoso Daniel Escorsim Machado Mayara Calixto da Silva Matheus Pereira de Mello Plinio Tostes Berardo Rui Medeiros Jamila Alessandra Perini Source Type: research

Influence of interleukin-8 polymorphism on endometriosis-related pelvic pain
Hum Immunol. 2023 Jul 17:S0198-8859(23)00113-1. doi: 10.1016/j.humimm.2023.07.004. Online ahead of print.ABSTRACTEndometriosis presents a pro-inflammatory microenvironment influenced by cytokines, such as interleukin (IL)-8, which expression may be influenced by genetic polymorphisms. Therefore, we aimed to investigate the role of interleukin (IL)-8 rs4073 polymorphism in endometriosis' development and its related symptoms. A case-control study was conducted with 207 women with endometriosis and 193 healthy controls. Polymorphism was genotyped using a TaqMan validated assay. Associations were evaluated by binary logistic r...
Source: Human Immunology - July 19, 2023 Category: Allergy & Immunology Authors: J éssica Vilarinho Cardoso Daniel Escorsim Machado Mayara Calixto da Silva Matheus Pereira de Mello Plinio Tostes Berardo Rui Medeiros Jamila Alessandra Perini Source Type: research