Reversible hypothalamic obesity in a girl with suprasellar tuberculoma
Conclusion: Suprasellar tuberculoma can have a very dynamic presentation during the active stage of the disease, which can be reversed by prolonged antituberculosis treatment. Previous studies showed that the tuberculous process can also cause long term and irreversible changes in the hypothalamic-pituitary axis. Prospective studies are however needed in the pediatric population to know the exact incidence and type of pituitary dysfunction. (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 28, 2023 Category: Endocrinology Source Type: research
An Overlooked Manifestation of Hypercortisolism - Cerebral Cortical Atrophy and Challenges in Identifying the Etiology of Hypercortisolism: A Report of 2 Pediatric Cases
Discussion: Endogen ous hypercortisolism may cause brain atrophy of varying severity. Central nervous system findings can be overlooked in children with CS. More comprehensive studies are needed to better understand the behavioral changes caused by the effects on the brain and to evaluate whether these changes are reve rsible. In addition, identifying the source of hypercortisolism can be difficult due to a lack of experience related to the rarity of the disease in children. (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 27, 2023 Category: Endocrinology Source Type: research
Erratum
Horm Res Paediatr (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 2, 2023 Category: Endocrinology Source Type: research
Subject Index Vol. 96, No. 1, 2023
Horm Res Paediatr 2023;96:110 (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 1, 2023 Category: Endocrinology Source Type: research
Author Index Vol. 96, No. 1, 2023
Horm Res Paediatr 2023;96:109 (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 1, 2023 Category: Endocrinology Source Type: research
Preliminary Pages
Horm Res Paediatr 2023;96:1 –4 (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - March 1, 2023 Category: Endocrinology Source Type: research
XXX Annual Meeting of the Latin American Pediatric Endocrinology Society (SLEP) Bogota, Colombia, October 19-22, 2022
XXX Annual Meeting of the Latin American Pediatric Endocrinology Society (SLEP)
Bogota, Colombia, October 19 –22, 2022Horm Res Paediatr 2023;96:1 –53 (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 24, 2023 Category: Endocrinology Source Type: research
11th International Meeting of Paediatric Endocrinology (IMPE) - Abstracts
naHorm Res Paediatr 2023;Vol.:1 –197 (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 24, 2023 Category: Endocrinology Source Type: research
Novel Calcium-Sensing Receptor (CASR) Mutation in a Family with Autosomal Dominant Hypocalcemia Type 1 (ADH1): Genetic Study over Three Generations and Clinical Characteristics
We report on a family with seven members over three generations with ADH1 due to a novel heterozygous mutation in exon 4 of CASR: c.416T>C. This mutation leads to substitution of isoleucine with threonine in the ligand-binding domain of CASR. HEK293T cells transfected with wild type or mutant cDNAs demonstrated that p.Ile139Thr substitution led to increased sensitivity of the CASR to activation by extracellular calcium relative to the wild type CASR (EC50 of 0.88 ± 0.02 mM vs.1.1 ± 0.23 mM respectively, p (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 22, 2023 Category: Endocrinology Source Type: research
Compromised adult height in females with non-classical congenital adrenal hyperplasia diagnosed in childhood
Introduction
Data on adult height (AHt) in individuals with non-classical congenital adrenal hyperplasia (NCCAH) are inconsistent.
Methods
We conducted a retrospective study of 109 females diagnosed with NCCAH at age (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 20, 2023 Category: Endocrinology Source Type: research
Erratum
Horm Res Paediatr (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 17, 2023 Category: Endocrinology Source Type: research
Review of implant gonadotrophin-releasing hormone agonist use: experience in a single academic center
Background: Gonadotrophin-releasing hormone agonists (GnRHa) are used for puberty suppression in central precocious puberty (CPP) and gender dysphoria (GD). Guidelines on biochemical monitoring are not defined.
Objectives: To evaluate the utility of biochemical monitoring of GnRHa therapy in patients with CPP or GD.
Methods: Retrospective chart review of patients 18 years or younger who received GnRHa therapy from 1/1/2018 to 3/2/2021.
Results: 103 patients were evaluated, 43 with CPP and 60 with GD. Using thresholds of basal luteinizing hormone (LH) (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 15, 2023 Category: Endocrinology Source Type: research
Rhabdomyolysis: A rare presentation of Hashimoto thyroiditis in an adolescent boy and review of the literature
Conclusion:
It is important for clinicians to be aware that rhabdomyolysis may be a presenting sign of severe hypothyroidism, as delay in diagnosis and treatment can be detrimental. (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 13, 2023 Category: Endocrinology Source Type: research
Infants with Congenital Adrenal Hyperplasia Exhibit Thalamic Discrepancies in Early Brain Structure
Conclusions: Infants with CAH exhibit smaller thalamic regions from earl y life, suggesting a prenatal influence on brain development in CAH. Thalamic emergence at 8-14 weeks makes the region particularly vulnerable to changes in the intrauterine environment, with potential implications for later maturing brain regions. These changes may take time to manifest, meriting l ongitudinal study through adolescence in CAH. (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - February 1, 2023 Category: Endocrinology Source Type: research
