High-fidelity simulation training programme for final-year medical students: implications from the perceived learning outcomes.
Abstract We designed a session of high-fidelity simulation training course for final-year medical students in their emergency medicine specialty clerkship. This was a new initiative with clearly defined learning outcomes. We aimed to evaluate the learning outcomes. Students completed an evaluation form at the end of the session focusing on their perceived learning outcomes. Thematic analysis was conducted for data processing. We collected responses from 149 students. In addition to the intended outcomes of the course, students gained unexpected learning outcomes from the training and some of them matched a few ide...
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Choi YF, Wong TW Tags: Hong Kong Med J Source Type: research

Persistent hypoglossal artery with a contralateral hypoglossal canal venous lake: a case report.
PMID: 31761749 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Vaz N, Poon WL, Cheng SS Tags: Hong Kong Med J Source Type: research

Vaginal stone formation secondary to vaginal tape exposure for stress urinary incontinence: a case report.
PMID: 31761750 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Yu MCH Tags: Hong Kong Med J Source Type: research

Type A aortic dissection involving the superior mesenteric artery with peripheral malperfusion managed with a hybrid approach: a case report.
PMID: 31761751 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Cheng M, Lee KY Tags: Hong Kong Med J Source Type: research

Diagnosis of Wunderlich syndrome in a patient with flank pain.
PMID: 31761752 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lin YY, Hsu CW, Li HM, Su HY Tags: Hong Kong Med J Source Type: research

Sudden cardiac arrest with pericardial contrast during computed tomography aortogram in a type A aortic dissection patient.
PMID: 31761753 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Yu WM, Wong WL, Ng FH Tags: Hong Kong Med J Source Type: research

Management of bilateral rhino-orbital cerebral mucormycosis.
PMID: 31761754 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lam SC, Yuen HKL Tags: Hong Kong Med J Source Type: research

Posterior reversible encephalopathy syndrome as a neuropsychiatric manifestation of systemic lupus erythematosus.
PMID: 31761755 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Ho CM, Mok CC Tags: Hong Kong Med J Source Type: research

Tragic deaths by choking in healthy children.
PMID: 31761756 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Hon KL, Ku ASW Tags: Hong Kong Med J Source Type: research

Streptococcus bovis bacteraemia should be investigated for early detection of colorectal pathology.
PMID: 31761757 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Ng SC, Wong HK, So CK, Lau CW, Leung JNS, Tsoi WC, Lee CK Tags: Hong Kong Med J Source Type: research

Healing hearts in paediatrics: an interview with Dr Adolphus Chau.
PMID: 31761758 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lam C, Cheuk N, Yeung C Tags: Hong Kong Med J Source Type: research

Drainage apparatus for treating pneumothorax.
PMID: 31761759 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Wu HYJ Tags: Hong Kong Med J Source Type: research

Hong Kong domestic health spending: financial years 1989/90 to 2016/17.
PMID: 31761760 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lee PY, Johnston JM, Lee PSL, Lee YH, Poon KKY, Lam DWS, Yeung AYT, Lam K, Ma ESK Tags: Hong Kong Med J Source Type: research

Editorial.
PMID: 31761761 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Ma ESK, Collins RA Tags: Hong Kong Med J Source Type: research

Serum amyloid A1 polymorphisms as risk factors in oesophageal squamous cell carcinoma.
PMID: 31761762 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lung HL, Lung ML, Law S Tags: Hong Kong Med J Source Type: research

Chinese parental decision making on HPV vaccination for adolescent girls: a longitudinal study.
PMID: 31761763 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Fielding R, Lam WWT, Wu JTK, Wang LDL, Liao QY Tags: Hong Kong Med J Source Type: research

DNA sequence patterns in human major histocompatibility complex region in southern Chinese.
PMID: 31761764 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Song YQ, Sham PS, Yip SP, Fan YH, Bao SY Tags: Hong Kong Med J Source Type: research

Novel PCDH10-Wnt-MALAT1 regulatory axis in endometrioid endometrial adenocarcinoma.
PMID: 31761765 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Zhao Y, Yang Y, Trovik J, Sun K, Zhou L, Jiang P, Lau TS, Hoivik EA, Salvesen HB, Sun H, Wang H Tags: Hong Kong Med J Source Type: research

Influenza virus infections in Hong Kong in 2013-14: a community-based longitudinal seroepidemiological study.
PMID: 31761766 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Cowling BJ, Peiris JSM, Kwok KO Tags: Hong Kong Med J Source Type: research

Innate immune defect predisposing to severe influenza in a Chinese population.
PMID: 31761767 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: To KKW, Zhou J, Song YQ, Hung IFN, Yuen KY Tags: Hong Kong Med J Source Type: research

B-1 cell response and its regulation during influenza virus infection.
PMID: 31761768 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lu L, Wang X, Ma K, Chen M, Ko KH, Zheng BJ Tags: Hong Kong Med J Source Type: research

Vaccine-induced T cell protection from influenza viruses.
PMID: 31761769 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Valkenburg SA, Li OTW, Peiris JSM, Perera LP, Poon LLM Tags: Hong Kong Med J Source Type: research

Transfer of HIV-1 from HIV-1 latently infected CD34+ haematopoietic progenitors to CD4+ T cells.
PMID: 31761770 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Cheung AKL, Huang Y, Chen M, Chen ZW Tags: Hong Kong Med J Source Type: research

Foreign language learning as potential treatment for mild cognitive impairment.
PMID: 31761771 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Wong PCM, Ou J, Pang CWY, Zhang L, Tse CS, Lam LCW, Antoniou M Tags: Hong Kong Med J Source Type: research

FE65 serine-610 phosphorylation and its functional implications in Alzheimer disease amyloid precursor protein processing.
PMID: 31761772 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Authors: Lau KF, Chow WN, Ngo JCK, Chen YW, Tam VKM, Chan EHY, Miller C Tags: Hong Kong Med J Source Type: research

6th Hong Kong Neurological Congress cum 32nd Annual Scientific Meeting of The Hong Kong Neurological Society.
Authors: PMID: 31761773 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - September 30, 2019 Category: General Medicine Tags: Hong Kong Med J Source Type: research

Survey on common reference intervals for general chemistry analytes in Hong Kong.
CONCLUSIONS: We recommend the use of common RIs for general chemistry analytes in Hong Kong to prevent interpreter confusion, improve electronic data transfer, and unite laboratory practice. This is the first local study on this topic, and our data can lay the groundwork for increasing harmonisation of RIs across more laboratory tests. PMID: 31402339 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 11, 2019 Category: General Medicine Authors: Chan TCH, Mak CM, Chen SPL, Leung MT, Cheung HN, Leung DCW, Lee HK, Koo EC, Lo YC Tags: Hong Kong Med J Source Type: research

Pathogens in preterm prelabour rupture of membranes and erythromycin for antibiotic prophylaxis: a retrospective analysis.
CONCLUSION: Gram-positive and Gram-negative bacteria were found in 29.1% of PPROM patients. Administration of erythromycin alone was insufficient to control these bacteria in 67.7% of patients with positive cultures. PMID: 31402340 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 11, 2019 Category: General Medicine Authors: Li YY, Kong CW, To WWK Tags: Hong Kong Med J Source Type: research

Local infiltration analgesia in primary total knee arthroplasty.
CONCLUSIONS: Intra-operative single-dose LIA can effectively reduce postoperative pain, morphine demand, and morphine consumption. Therefore, the use of LIA is recommended during TKA. PMID: 31395787 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 4, 2019 Category: General Medicine Authors: Fang YY, Lee QJ, Chang EWY, Wong YC Tags: Hong Kong Med J Source Type: research

Prevalence of obstetric anal sphincter injury following vaginal delivery in primiparous women: a retrospective analysis.
CONCLUSIONS: Additional training for midwives and doctors may improve OASIS detection. PMID: 31395788 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 4, 2019 Category: General Medicine Authors: Kwok SPK, Wan OYK, Cheung RYK, Lee LL, Chung JPW, Chan SSC Tags: Hong Kong Med J Source Type: research

Common urological problems in children: primary nocturnal enuresis.
Abstract Enuresis is a common complaint in children, with a prevalence of around 15% at age 6 years. Evidence suggests that enuresis could affect neuropsychiatric development. The condition may represent an entire spectrum of underlying urological conditions. It is important to understand the difference between monosymptomatic and non-monosymptomatic enuresis. Primary monosymptomatic enuresis can be managed efficaciously with care in different settings, like primary care, specialist nursing, or paediatric specialists, while non-monosymptomatic enuresis requires more complex evaluation and treatment. The diagnosis,...
Source: Hong Kong Med J - August 4, 2019 Category: General Medicine Authors: Chan IHY, Wong KKY Tags: Hong Kong Med J Source Type: research

Parental consanguinity in Hong Kong.
CONCLUSIONS: It is essential that information on the increased risks associated with parental consanguinity is included in genetic counselling for consanguineous couples, so that they can make informed decisions. PMID: 31178441 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - June 9, 2019 Category: General Medicine Authors: Siong KH, Au Yeung SKC, Leung TY Tags: Hong Kong Med J Source Type: research

Peanut allergy and oral immunotherapy.
Abstract Peanut allergy is the commonest cause of food-induced anaphylaxis in the world, and it can be fatal. There have been many recent improvements to achieve safe methods of peanut desensitisation, one of which is to use a combination of anti-immunoglobulin E and oral immunotherapy. We have treated 27 patients with anti-immunoglobulin E and oral immunotherapy, and report on the outcomes and incidence of adverse reactions encountered during treatment. The dose of peanut protein tolerated increased from a median baseline of 5 to 2000 mg after desensitisation, which is substantially more than would be encountered...
Source: Hong Kong Med J - June 9, 2019 Category: General Medicine Authors: Lee TH, Chan JKC, Lau PC, Luk WP, Fung LH Tags: Hong Kong Med J Source Type: research

Hong Kong needs a territory-wide registry for out-of-hospital cardiac arrest.
Abstract Out-of-hospital cardiac arrest (OHCA) is an urgent disease entity, and the outcomes of OHCA are poor. This causes a significant public health burden, with loss of life and productivity throughout society. Internationally, successful programmes have adopted various survival enhancement measures to improve outcomes of OHCA. A territory-wide organised survival enhancement campaign is required in Hong Kong to maintain OHCA survival rates that are comparable to those of other large cities. One key component is to establish an OHCA registry, such as those in Asia, the United States, Europe, Australia, and New Z...
Source: Hong Kong Med J - June 9, 2019 Category: General Medicine Authors: Lui CT, Lau CL, Siu AYC, Fan KL, Leung LP Tags: Hong Kong Med J Source Type: research

Outcomes of transperineal and transrectal ultrasound-guided prostate biopsy.
CONCLUSION: For prostate biopsy, TPUSPB is safer, with no infection complications, and has similar prostate cancer detection rate compared with TRUSPB. PMID: 31178436 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 28, 2019 Category: General Medicine Authors: Lo KL, Chui KL, Leung CH, Ma SF, Lim K, Ng T, Wong J, Li JKM, Mak SK, Ng CF Tags: Hong Kong Med J Source Type: research

Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong.
CONCLUSION: Our results confirm that FMT is a safe, efficacious, and feasible intervention for patients with refractory or recurrent CDI in Hong Kong. Given the increasing disease burden and the lack of effective alternatives in Hong Kong for difficult-to-treat cases of CDI, we recommend that a territory-wide FMT service be established to address increasing demand for this treatment. PMID: 31178437 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 28, 2019 Category: General Medicine Authors: Lui RN, Wong SH, Lau LHS, Chan TT, Cheung KCY, Li AYL, Chin ML, Tang WWY, Ching JYL, Lam KLY, Chan PKS, Wu JCY, Sung JJY, Chan FKL, Ng SC Tags: Hong Kong Med J Source Type: research

Questionnaire survey on medical futility and termination of resuscitation in cardiac arrest patients among emergency physicians in Hong Kong.
CONCLUSION: Clinical practice and behaviour of TOR was not demonstrated to have associations with knowledge or attitude. Status as a Fellow of the Hong Kong College of Emergency Medicine or Advanced Cardiac Life Support instructor were the only two parameters identified that had significant relationships with earlier TOR in medically futile patients with OHCA. PMID: 31178438 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 28, 2019 Category: General Medicine Authors: So CW, Lui CT, Tsui KL, Chan KL, Law AKK, Wong YK, Li T, Wong CL, Leung SC Tags: Hong Kong Med J Source Type: research

Statins role in preventing contrast-induced acute kidney injury: a scoping review.
CONCLUSION: Statin therapy can be used as an adjunct to usual prophylactic measures such as adequate hydration and use of low-volume contrast media. Large well-designed trials on the effects of short-term high-dose statin use in preventing CI-AKI should be conducted, to eliminate any form of discrepancy among results, and to clarify any potential adverse effects. PMID: 31178439 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 28, 2019 Category: General Medicine Authors: Anjum I, Akmal M, Hasnain N, Jahangir M, Sohail W Tags: Hong Kong Med J Source Type: research

Budget impact of introducing tofacitinib to the public hospital formulary in Hong Kong, 2017-2021.
CONCLUSION: Introduction of tofacitinib to the formulary will provide 5-year savings, given the current drug price and patient volume. PMID: 31178440 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 28, 2019 Category: General Medicine Authors: Li X, Pathadka S, Man KK, Wong ICK, Chan EWY Tags: Hong Kong Med J Source Type: research

Infection control in residential care homes for the elderly in Hong Kong (2005-2014).
Abstract INTRODUCTION: This serial cross-sectional survey study aimed to review the trend in various infection control practices in residential care homes for the elderly (RCHEs) in Hong Kong from 2005 to 2014. METHODS: Annual cross-sectional surveys were conducted at all RCHEs in Hong Kong, including self-administered questionnaires, on-site interviews, inspections, and assessments conducted by trained nurses, from 2005 to 2014. In all, 98.5% to 100% of all RCHEs were surveyed each year based on the list of licensed RCHEs in Hong Kong. RESULTS: There was a substantial increase in the proportion of RCHE ...
Source: Hong Kong Med J - April 9, 2019 Category: General Medicine Authors: Wong GCY, Ng T, Li T Tags: Hong Kong Med J Source Type: research

Poisoning by toxic plants in Hong Kong: a 15-year review.
CONCLUSIONS: Although most plant exposure resulted in a self-limiting disease, severe poisonings were encountered. Epidemiology of plant poisonings is geographically specific. Clinicians should be aware of local poisonous plants and their toxicities. PMID: 30967518 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - April 9, 2019 Category: General Medicine Authors: Ng WY, Hung LY, Lam YH, Chan SS, Pang KS, Chong YK, Ching CK, Mak TWL Tags: Hong Kong Med J Source Type: research

Rubella (German measles) revisited.
Abstract Rubella is generally a mild and self-limited disease in children. During pregnancy, rubella can have potentially devastating effects on the developing fetus. Postnatal rubella is transmitted primarily by inhalation of virus-laden airborne droplets or direct contact with infected nasopharyngeal secretions. In susceptible pregnant women, the virus may cross the placenta and spread through the vascular system of the developing fetus. Postnatally acquired rubella typically begins with fever and lymphadenopathy, followed by an erythematous, maculopapular rash. The rash classically begins on the face, spreads c...
Source: Hong Kong Med J - April 9, 2019 Category: General Medicine Authors: Leung AKC, Hon KL, Leong KF Tags: Hong Kong Med J Source Type: research

Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial.
This study aimed to evaluate the efficacy and safety of a three-dose regimen of tranexamic acid on blood loss and transfusion rate in elderly patients with trochanteric fractures. METHODS: Eligible patients with trochanteric fractures surgically treated by dynamic hip screw and proximal anti-rotating intramedullary nail between March 2016 and October 2017 were enrolled in the study. Patients were randomly assigned to receive 15 mg/kg intravenous tranexamic acid dissolved in 100 mL of saline (TXA group) or 100 mL of saline solution (placebo group) over 10 minutes before, during, and after surgery. Perioperative blood l...
Source: Hong Kong Med J - March 27, 2019 Category: General Medicine Authors: Chen F, Jiang Z, Li M, Zhu X Tags: Hong Kong Med J Source Type: research

Non-surgical treatment of knee osteoarthritis.
Abstract Knee osteoarthritis is one of the most common degenerative diseases causing disability in elderly patients. Osteoarthritis is an increasing problem for ageing populations, such as that in Hong Kong. It is important for guidelines to be kept up to date with the best evidence-based osteoarthritis management practices available. The aim of this study was to review the current literature and international guidelines on non-surgical treatments for knee osteoarthritis and compared these with the current guidelines in Hong Kong, which were proposed in 2005. Internationally, exercise programmes for non-surgical m...
Source: Hong Kong Med J - March 27, 2019 Category: General Medicine Authors: Kan HS, Chan PK, Chiu KY, Yan CH, Yeung SS, Ng YL, Shiu KW, Ho T Tags: Hong Kong Med J Source Type: research

Enhanced recovery after surgery for liver resection.
CONCLUSIONS: The ERAS perioperative programme for liver resection is safe and feasible. It significantly shortened the hospital stay after open liver resection but not after laparoscopic liver resection. PMID: 30919808 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - March 26, 2019 Category: General Medicine Authors: Chong CC, Chung WY, Cheung YS, Fung AK, Fong AK, Lok HT, Wong J, Lee KF, Chan SK, Lai PB Tags: Hong Kong Med J Source Type: research

Editorial.
PMID: 30792362 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Ma ES, Collins RA Tags: Hong Kong Med J Source Type: research

Extended early intervention versus standard psychiatric care for adults with first-episode psychosis.
PMID: 30792363 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Chang WC, Chan SK, Lee EH, Hui CL, Chen EY Tags: Hong Kong Med J Source Type: research

Stepped care programme in primary care to prevent anxiety and depression: a randomised clinical trial.
PMID: 30792364 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Wong SY, Tang WK, Mak WW, Cheung FM, Mercer S, Griffiths SM, Woo J, Lee DT, Kung K, Lam AT Tags: Hong Kong Med J Source Type: research

15-year computer-record study of adolescents exposed to peer suicide.
PMID: 30792365 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Tang CP, Hung SF, Lee CC, Ho TP, Leung PW Tags: Hong Kong Med J Source Type: research

Adolescent alcohol drinking in Hong Kong: a school-based survey.
PMID: 30792366 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Ho DS, Huang R, Wang MP, Lo WS, Lam TH Tags: Hong Kong Med J Source Type: research