Evaluation of Post-Exposure Prophylaxis Utilization Among Human Immunodeficiency Virus Exposed Victims at University of Gondar Comprehensive Specialized Hospital, North West Ethiopia
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - January 21, 2020 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Factors Influencing Effectiveness of Peer Education Against Nonadherence to Antiretroviral Therapy Among Adult People Living with HIV/AIDS: A Pre-Post Intervention Study in Arsi Zone, Ethiopia
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - January 9, 2020 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Dolutegravir And Lamivudine Combination For The Treatment Of HIV-1 Infection
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - October 23, 2019 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Perceived stigma among people living with HIV AIDS in Pokhara, Nepal
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - May 7, 2019 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Analysis of HIV testing refusal among patients aged less than 21 years in the Pediatric Emergency Department
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - October 8, 2018 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

HIV awareness and safe sexual behaviors among female sex workers in Kathmandu valley of Nepal
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - August 21, 2018 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Medical decision making and risky choices: psychological and medicolegal consequences of HIV and HCV contamination of blood products
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - August 24, 2017 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - March 30, 2017 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Predictors of hypertension in an urban HIV-infected population at the University of Calabar Teaching Hospital, Calabar, Nigeria
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - February 14, 2017 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Seroprevalence of human immunodeficiency virus among voluntary counseling and testing clients at the University of Gondar Teaching Hospital, Northwest Ethiopia
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - August 16, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Decreases in human immunodeficiency virus infection rates in Kombolcha, Ethiopia: a 10-year data review
(Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - July 7, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Knowledge of pregnant women on mother-to-child transmission of HIV, its prevention, and associated factors in Assosa town, Northwest Ethiopia
Conclusion: Knowledge on MTCT and its prevention among women is low in the study area. We recommend more efforts to be exerted on improving women's knowledge of PMTCT of HIV.Keywords: pregnant women, mother-to-child transmission and prevention, Assosa (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - May 5, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning
Conclusion: These findings provide in vivo support that HIV and MAD alter expression of FGFs, which may contribute to the NC abnormalities associated with these conditions. These cross-sectional findings cannot establish causality and the therapeutic benefits of recombinant FGF-1 need to be investigated. Keywords: biomarker, cerebrospinal fluid, fibroblast growth factor, HIV, methamphetamine, HIV-associated neurocognitive disorders, HAND, neurocognitive impairment (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - April 29, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Predictors of loss to follow-up in antiretroviral treatment for adult patients in the Oromia region, Ethiopia
Abebe Megerso,1 Sileshi Garoma,1 Tolosa Eticha,2 Tilaye Workineh,1 Shallo Daba,3 Mihretu Tarekegn,3 Zelalem Habtamu31Department of Public Health, Adama Hospital Medical College,2Department of Pediatrics and Child Health, Adama Hospital Medical College, 3Oromia Regional Health Bureau, HIV/AIDS prevention and Control Division, Addis Ababa, Ethiopia Purpose: It is known that antiretroviral treatment (ART) reduces mortality from acquired immunodeficiency syndrome related causes. Patient's lost to follow-up (LTFU) in this treatment poses a paramount problem to the public and health care services. Information on predict...
Source: HIV/AIDS - Research and Palliative Care - April 26, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Magnitude of visceral leishmaniasis and poor treatment outcome among HIV patients: meta-analysis and systematic review
Conclusion: The pooled prevalence of VL in HIV-infected patients is low and an earlier bout of VL and CD4+ count
Source: HIV/AIDS - Research and Palliative Care - March 23, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Economic and health implications from earlier detection of HIV infection in the United Kingdom
Conclusion: The results strengthen the rationale for implementing increased testing in high prevalence areas. However, in areas of low prevalence, it is unlikely that costs will be returned over a 5-year period. Keywords: HIV, testing, costs, savings, model (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - March 15, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection
Rustin D Crutchley,1 Rakesh C Guduru,2 Amy M Cheng1 1Department of Pharmacy Practice and Translational Research, College of Pharmacy, University of Houston, 2CompanionDX, Houston, TX, USA Abstract: Atazanavir/cobicistat (ATV/c) and darunavir/cobicistat (DRV/c) are newly approved once daily fixed-dose protease inhibitor combinations for the treatment of HIV-1 infection. Studies in healthy volunteers have established bioequivalence between cobicistat and ritonavir as pharmacoenhancers of both atazanavir (ATV) and darunavir (DRV). In addition, two randomized clinical trials (one Phase II and one Phase III noninferiority trial...
Source: HIV/AIDS - Research and Palliative Care - March 9, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS
Melissa E Badowski,1 Sarah E Perez2 1Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; 2Infectious Diseases Clinic, Tufts Medical Center, Boston, MA, USA Abstract: Since the beginning of the HIV/AIDS epidemic, weight loss has been a common complaint for patients. The use of various definitions defining HIV wasting syndrome has made it difficult to determine its actual prevalence. Despite the use of highly active antiretroviral therapy, it is estimated that the prevalence of HIV wasting syndrome is between 14% and 38%. H...
Source: HIV/AIDS - Research and Palliative Care - February 10, 2016 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

HIV and smoking: associated risks and prevention strategies
Wanjiku Kariuki,1 Jennifer I Manuel,2 Ngaruiya Kariuki,3 Ellen Tuchman,2 Johnnie O'Neal,4 Genevieve A Lalanne2 1University of Texas School of Public Health, Department of Management, Policy, and Community Health, Houston, TX, 2Silver School of Social Work, New York University, New York, 3Internal Medicine Department, Maimonides Medical Center, Brooklyn, 4Department of Social Work, The College of New Rochelle, New Rochelle, NY, USA Abstract: High rates of smoking among persons living with HIV (PLWH) may reduce the effectiveness of HIV treatment and contribute to significant morbidity and mortality. Factors associated wi...
Source: HIV/AIDS - Research and Palliative Care - December 23, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Clinical use of cobicistat as a pharmacoenhancer of human immunodeficiency virus therapy
This article reviews the current literature, and compares the pharmacokinetics, pharmacodynamics, and safety of both pharmacoenhancers and discusses the clinical utility of cobicistat in up-to-date and future HIV therapy. Keywords: human immunodeficiency virus, fixed-dose combinations, pharmacoenhancers, drug safety (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - December 22, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

HIV-1 subtype characteristics of infected persons living in southwestern Greece
Conclusion: HIV-1 infection in southwestern Greece is sexually transmitted and highly heterogeneous. Subtype A1 has surpassed subtype B, and is the most prevalent strain. In the population studied, subtype A1 exhibited certain polymorphisms in the protease region, which may serve as drug-resistance support mutations in subtype B. Keywords: HIV-1 infection, transmission, subtype, sequence, genetic signatures, epidemiology (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - December 11, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Gene expression profiles and protein–protein interaction network analysis in AIDS patients with HIV-associated encephalitis and dementia
In conclusion, the results indicate that HSP90A and fibronectin 1 play important roles in HIVE pathogenesis.Keywords: microarray, human immunodeficiency virus, differentially expressed genes, protein–protein interaction network, gene ontology, encephalitis, dementia (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - November 17, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Management of HIV/AIDS in older patients–drug/drug interactions and adherence to antiretroviral therapy
Mary J Burgess,1 John D Zeuli,2 Mary J Kasten31Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Department of Pharmacy, Mayo Clinic, Rochester, MN, USA; 3Divisions of General Internal Medicine and Infectious Diseases, Mayo Clinic, Rochester, MN, USAAbstract: Patients with human immunodeficiency virus (HIV) are living longer with their disease, as HIV has become a chronic illness managed with combination antiretroviral therapy (cART). This has led to an increasing number of patients greater than 50 years old living successfully with HIV. As the number of older adults with ...
Source: HIV/AIDS - Research and Palliative Care - October 27, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Preexposure prophylaxis-related stigma: strategies to improve uptake and adherence – a narrative review
Bridget G Haire Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia Abstract: Despite high levels of efficacy, the implementation of preexposure prophylaxis (PrEP) as a strategy to prevent new HIV infection has been slow. Studies show that PrEP works so long as it is taken, making adherence one of the great challenges of effective PrEP implementation alongside issues of access and uptake. Given that effective PrEP use requires ongoing self-administration of pills by people at high risk of HIV acquisition, it is a strategy best understood not as simply biomedical, but...
Source: HIV/AIDS - Research and Palliative Care - October 13, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Peer supporter experiences of home visits for people with HIV infection
Conclusion: The findings suggest that to maintain a stable and effective peer supporter program, such positions require financial support, training in how to prevent and manage stress associated with the role, and a well-developed program of education and training.Keywords: human immunodeficiency virus, qualitative research, workplace experience (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - September 24, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Peer supporter experiences
Lee HJ, Moneyham L, Kang HS, Kim KS (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - September 24, 2015 Category: Infectious Diseases Source Type: research

Identification of risk factors for hepatitis B and C in Peshawar, Pakistan
Conclusion: The important risk factors, responsible for the high prevalence of hepatitis B and C in our society are household contact, history of dental work, history of surgery, sexual contact, and history of transfusion (blood and its components). The odds ratio of probability for these risk factors are: 4.2 for household contact history, 4.1 for history of dental work, 3.9 for sexual contact, 2.7 for history of surgery, and 2.1 for history of transfusion. Associations of other predictor variables (diabetes status, education level, profession, contact sports, intravenous drug abuse, residence, immunosuppression, and skin...
Source: HIV/AIDS - Research and Palliative Care - August 17, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Predictors of HIV-test utilization in PMTCT among antenatal care attendees in government health centers: institution-based cross-sectional study using health belief model in Addis Ababa, Ethiopia, 2013
This study identifies predictors and possible barriers of HIV-testing among antenatal care attendees based on the health belief model (HBM) in Addis Ababa, Ethiopia. Methods: The study was an institution-based cross-sectional survey conducted from September 1 to September 30, 2013. A total of 308 individuals were interviewed using structured questionnaires adopted and modified from similar studies. Data were collected through face-to-face interviews. A logistic regression was used to identify factors associated with HIV-test use. Results: In spite of satisfactory knowledge on HIV/AIDS transmission, participants are still a...
Source: HIV/AIDS - Research and Palliative Care - July 13, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Disclosure of HIV-positive status to sexual partner and associated factors among ART users in Mekelle Hospital
Conclusion: An HIV-positive status disclosure to a sexual partner in this study was lower than what was reported in other studies in Ethiopia. The duration of HIV-related care follow-up, knowing partner's HIV status, and prior discussion were the main factors that affected the practice of HIV-positive status disclosure to their sexual partners.Keywords: cross sectional, institution based, systematic sampling, multivariate analysis (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - July 9, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Factors associated with HIV counseling and testing and correlations with sexual behavior of teachers in primary and secondary schools in Addis Ababa, Ethiopia
Conclusion: No significant differences were observed between primary and secondary school teachers regarding factors associated with HCT and its correlation with sexual behavior. Gender, age, marital status, knowledge of HCT, and perceived risk were found to be factors associated with HCT uptake. Correlations between being faithful to a partner, inconsistent use of condoms, and HCT uptake of teachers were also observed. Thus, strengthening the current practice of HCT services in the education sector with due emphasis on the observed factors could play a pivotal role in bringing about positive changes in the sexual behavior...
Source: HIV/AIDS - Research and Palliative Care - June 30, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Prevalence of anemia and nutritional status among HIV-positive children receiving antiretroviral therapy in Harar, eastern Ethiopa
Zelalem Teklemariam,1 Habtamu Mitiku,1 Firehiwot Mesfin2 1Department of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia Purpose: Anemia and growth retardation are common manifestations of HIV-positive children, which threaten their lives. Therefore, this study tried to assess the burden of anemia and the nutritional status of HIV-positive children receiving antiretroviral therapy (ART) in eastern Ethiopa. Patients and methods: A total of 108 records of chi...
Source: HIV/AIDS - Research and Palliative Care - June 5, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Sexual behaviors and associated factors among antiretroviral treatment attendees in Ethiopia
This study aimed to assess risky sexual practice and associated factors among HIV-positive ART attendees. Methods: An institution-based cross-sectional study was employed in ten randomly selected health centers in Addis Ababa, between October 05 and November 05, 2013. Simple random sampling technique was employed to select 376 respondents for face-to-face interviews from ART registration book. After the data collection process, data were entered and analyzed using the SPSS version 20 statistical package. Then the effect of each variable was observed by regression analysis to identify the predictors for risky sexual practic...
Source: HIV/AIDS - Research and Palliative Care - June 3, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Magnitude of HIV and syphilis seroprevalence among pregnant women in Gondar, Northwest Ethiopia: a cross-sectional study
Conclusion: Seroprevalence of HIV and syphilis was high. Low husband educational status was a risk factor for HIV and syphilis. Therefore, substantial efforts have to be made to reinforce prevention strategies and to screen as early as possible to prevent mother-to-child and further horizontal transmission. Keywords: HIV, magnitude, seroprevalence, syphilis (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - June 2, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Do loss to follow-up and death rates from ART care vary across primary health care facilities and hospitals in south Ethiopia? A retrospective follow-up study
Conclusion: We observed a higher death rate and a lower LTFU rate in health centers than in hospitals. Most of the associated variables were also previously documented. Higher LTFU was noticed for patients with a smaller gap between testing and initiation of treatment. Keywords: antiretroviral therapy, primary care, loss to follow-up, death rates, Ethiopia (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - May 28, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Factors affecting acceptance of provider-initiated HIV testing and counseling services among outpatient clients in selected health facilities in Harar Town, Eastern Ethiopia
Conclusion: There is evidence of the relatively increased acceptability of PITC services by outpatient department clients. A program needs to be strengthened to enhance the use of PITC; the Ministry of Health, Regional Health Bureau, and other responsible bodies – including health facilities – should design and strengthen information education and communication/behavioral change and communication interventions and promote activities related to PITC and HIV counseling and testing in both health facilities and the community at large. Keywords: PITC, outpatient clients, Harar town, Eastern Ethiopia (Source: HIV/AI...
Source: HIV/AIDS - Research and Palliative Care - May 15, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Dyslipidemia and cardiovascular disease risk profiles of patients attending an HIV treatment clinic in Harare, Zimbabwe
Danai Tavonga Zhou,1,2 Vitaris Kodogo,1 Kudzai Fortunate Vongai Chokuona,1 Exnevia Gomo,1 Olav Oektedalen,3 Babill Stray-Pedersen21Department of Medical Laboratory Sciences, College of Health Sciences, University of Zimbabwe, Avondale, Zimbabwe; 2Institute of Clinical Medicine, University in Oslo, Oslo University Hospital, Oslo, Norway; 3Department of Infectious Diseases, Oslo University Hospital, Oslo, NorwayAbstract: The chronic inflammation induced by human immunodeficiency virus (HIV) contributes to increased risk of coronary heart disease (CHD) in HIV-infected individuals. HIV-infected patients generally benefit from ...
Source: HIV/AIDS - Research and Palliative Care - May 13, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Magnitude of opportunistic infections and associated factors in HIV-infected adults on antiretroviral therapy in eastern Ethiopia
Habtamu Mitiku, Fitsum Weldegebreal, Zelalem Teklemariam Haramaya University, College of Health and Medical Sciences, Department of Medical Laboratory Sciences, Harar, Ethiopia Purpose: The aim of this study was to assess the prevalence of opportunistic infections (OIs) and associated factors among HIV-infected adults on anti-retroviral therapy (ART) in Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Patients and methods: A hospital-based retrospective study was conducted in 358 HIV-infected adult patients on ART from April to June 2014. Data were collected through review of clinical records. The data was ent...
Source: HIV/AIDS - Research and Palliative Care - May 12, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Pre-exposure prophylaxis for sexually-acquired HIV risk management: a review
James Wilton,1 Heather Senn,2 Malika Sharma,3 Darrell HS Tan4,5 1Canadian AIDS Treatment Information Exchange (CATIE), 2Department of Family and Community Medicine, University of Toronto, 3Wilson Centre for Research in Education, University Health Network, University of Toronto, 4Division of Infectious Diseases, St Michael's Hospital, 5Department of Medicine, University of Toronto, Toronto, ON, Canada Abstract: Despite significant efforts, the rate of new HIV infections worldwide remains unacceptably high, highlighting the need for new HIV prevention strategies. HIV pre-exposure prophylaxis (PrEP) is a new approach tha...
Source: HIV/AIDS - Research and Palliative Care - April 28, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Consistent condom use in HIV/AIDS patients receiving antiretroviral therapy in northwestern Ethiopia: implication to reduce transmission and multiple infections
Conclusion: Females, patients living in rural areas, uneducated groups, and new ART users were less likely to use condoms consistently. The importance of consistent condom use should be well-addressed in HIV/AIDS patients, to prevent transmission and multiple infections of HIV. Keywords: barrier method against HIV, patients on ART, Ethiopia (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - April 13, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Factors influencing CD4 cell count in HIV-positive pregnant women in a secondary health center in Lagos, Nigeria
Conclusion: Maternal age, gestational age, and PCV at booking had no significant effects on CD4+ cell count levels in pregnancy. The mean CD4+ cell count of HIV-positive pregnant women in Lagos is 413.87±212.09 cells/µL. Keywords: mean value, reference range, HIV-pregnant women, immunity, pregnancy (Source: HIV/AIDS - Research and Palliative Care)
Source: HIV/AIDS - Research and Palliative Care - April 10, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Sociodemographic drivers of multiple sexual partnerships among women in three rural districts of Tanzania
This study examines prevalence and correlates of multiple sexual partnerships (MSP) among women aged 15+ years in Rufiji, Kilombero, and Ulanga districts of Tanzania. Materials and methods: Data were collected in a cross-sectional household survey in Rufiji, Kilombero, and Ulanga districts in Tanzania in 2011. From the survey, a total of 2,643 sexually active women ages 15+ years were selected for this analysis. While the chi-square test was used for testing association between MSP and each of the independent variables, logistic regression was used for multivariate analysis. Results: Number of sexual partners reported rang...
Source: HIV/AIDS - Research and Palliative Care - April 9, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research

HIV protease inhibitors: a review of molecular selectivity and toxicity
Zhengtong Lv,* Yuan Chu,* Yong Wang Department of Immunology, School of Basic Medical Science, Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China *Both authors contributed equally to this work Abstract: Highly active antiretroviral therapy (HAART) is recognized as the most effective treatment method for AIDS, and protease inhibitors play a very important role in HAART. However, poor bioavailability and unbearable toxicity are their common disadvantages. Thus, the development of safer and potentially promising protease inhibitors is eagerly needed. In this review, we introd...
Source: HIV/AIDS - Research and Palliative Care - April 8, 2015 Category: Infectious Diseases Tags: HIV/AIDS - Research and Palliative Care Source Type: research