Pharmacokinetics of meprobamate in overdose treated with continuous venovenous hemodiafiltration (CVVHDF)
We report a case of massive suicidal overdose of meprobamate leading to cardiovascular collapse, respiratory failure, and severe central nervous system depression. We observed first‐order elimination kinetics despite significant overdose, and demonstrated effectiveness of continuous venovenous hemodiafiltration (CVVHDF) for extracorporeal removal of meprobamate in this patient. Total body clearance was calculated to be 87 mL/minute, with 64 mL/minute (74%) due to CVVHDF. CVVHDF was stopped after 36 hours, and the patient made an uneventful recovery. (Source: Hemodialysis International)
Source: Hemodialysis International - April 25, 2013 Category: Hematology Authors: Alessandro Ceschi, David Berger, Michael Dickenmann, Michael Bodmer Tags: Case Report Source Type: research

Predictors of cardiovascular events in hemodialysis patients after stress myocardial perfusion imaging
This study evaluated prognostic factors of adverse cardiovascular events in hemodialysis patients in whom stress MPI was performed. Pharmacological stress MPI was performed in 88 hemodialysis patients, and we retrospectively followed‐up for 26 months. Cardiovascular events included cardiac death, nonfatal myocardial infarction, and unstable angina. Cardiovascular events occurred in 16 patients (18%). Univariate Cox regression analysis revealed that peripheral artery disease (PAD) and parameters of stress MPI were significant predictors of cardiovascular events. Multivariate Cox regression analysis revealed that only PAD ...
Source: Hemodialysis International - April 9, 2013 Category: Hematology Authors: Tatsuhiko Furuhashi, Masao Moroi, Nobuhiko Joki, Hiroki Hase, Megumi Minakawa, Hirofumi Masai, Taeko Kunimasa, Hiroshi Fukuda, Kaoru Sugi Tags: Original Article Source Type: research

Pre to post‐dialysis plasma sodium change better predicts clinical outcomes than dialysate to plasma sodium gradient in quotidian hemodialysis
Abstract Sodium balance across a hemodialysis treatment influences interdialytic weight gain (IDWG), pre‐dialysis blood pressure, and the occurrence of intradialytic hypotension, which associate with patient morbidity and mortality. In thrice weekly conventional hemodialysis patients, the dialysate sodium minus pre‐dialysis plasma sodium concentration (δDPNa+) and the post‐dialysis minus pre‐dialysis plasma sodium (δPNa+) are surrogates of sodium balance, and are associated with both cardiovascular and all‐cause mortality. However, whether δDPNa+ or δPNa+ better predicts clinical outcomes ...
Source: Hemodialysis International - April 3, 2013 Category: Hematology Authors: Benjamin K.A. Thomson, Shih‐Han S. Huang, Rosemary E. Leitch, Stephanie Dixon, Paul Heidenheim, Rita S. Suri, Christopher T. Chan, Robert M. Lindsay Tags: Original Article Source Type: research

Intratympanic steroid injection for sudden sensorineural hearing loss in a patient on hemodialysis
Abstract Sudden sensorineural hearing loss (SSNHL) is being described with increasing incidence among patients with end‐stage renal disease (ESRD) undergoing hemodialysis (HD). There are no widely accepted guidelines in the medical literature for the appropriate management of this medical emergency. Administration of systemic steroids remains the mainstay of the management of SSNHL in conjunction with the supportive treatment, in this vulnerable group of patients, as well. However, encouraged by the evolving evidence on the efficacy of the intratympanic steroid injections (ITSI) in the treatment of SSNHL among patients w...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Rui‐Xin Wu, Chun‐Chi Chen, Chih‐Hung Wang, Hsin‐Chien Chen Tags: Case Report Source Type: research

Methicillin‐resistant Staphylococcus aureus carriage in hospitalized chronic hemodialysis patients and its predisposing factors
Abstract There has been a paucity of literature on methicillin‐resistant Staphylococcus aureus (MRSA) colonization in chronic hemodialysis patients who required admission. The purpose of this study is to determine the MRSA carriage rate in hospitalized chronic hemodialysis patients, to identify the risk factors, and assess the consequences of MRSA colonization. This was a retrospective study of hospitalized chronic hemodialysis patients at Khoo Teck Puat Hospital from July 1, 2010 to June 30, 2011. MRSA screening was done on the day of admission using culture method with MRSA select (Bio‐Rad)™. The patients were ...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Lee Ying Yeoh, Feng Ling Grace Tan, George Christopher Willis, Say Tat Ooi Tags: Original Article Source Type: research

Impact of advanced dialysis technology on the prevalence of dialysis‐related amyloidosis in long‐term maintenance dialysis patients
Abstract Dialysis‐related amyloidosis (DRA) is a unique type of amyloidosis (beta‐2 microglobulin) predominantly in end‐stage renal disease. Its clinical manifestations add to increased morbidity and reduced quality of life. There seems to be a relative risk reduction in DRA manifestations when hemodialysis (HD) patients are treated with advanced HD technology, but changes of the course of DRA are uncertain. The aim of our investigation was to evaluate the prevalence and severity of carpal tunnel syndrome (CTS) in long‐term dialysis patients receiving either conventional or high‐flux, online‐produced ultrapure ...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Helmut Schiffl Tags: Original Article Source Type: research

Circulating cell‐free DNA levels in hemodialysis patients and its association with inflammation, iron metabolism, and rhEPO doses
(Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Michaela Kohlova, Sandra Ribeiro, Maria Sameiro‐Faria, Petronila Rocha‐Pereira, João Fernandes, Flávio Reis, Vasco Miranda, Alexandre Quintanilha, Luís Belo, Elsa Bronze‐Rocha, Elísio Costa, Alice Santos‐Silva Tags: Letter to the Editor Source Type: research

Who may not benefit from continuous renal replacement therapy in acute kidney injury?
This study aimed to identify factors that may predict early kidney recovery (less than 48 hours) or early death (within 48 hours) after initiating continuous renal replacement therapy (CRRT) in acute kidney injury (AKI) patients. This is a multicenter retrospective observational study of 14 Japanese Intensive care units (ICUs) in 12 tertiary hospitals. Consecutive adult patients with severe AKI requiring CRRT admitted to the participating ICUs in 2010 (n = 343) were included. Patient characteristics, variables at CRRT initiation, settings, and outcomes were collected. Patients were grouped into early kidney r...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Hiroo Kawarazaki, Shigehiko Uchino, Natsuko Tokuhira, Tetsu Ohnuma, Yoshitomo Namba, Shinshu Katayama, Noriyoshi Toki, Kenta Takeda, Hideto Yasuda, Junichi Izawa, Makiko Uji, Isao Nagata, Tags: Original Article Source Type: research

A high blood level in the venous chamber and a wet‐stored dialyzer help to reduce exposure for microemboli during hemodialysis
Abstract During hemodialysis (HD), microemboli develop in the blood circuit of the apparatus. These microemboli can pass through the venous chamber and enter into the patient's circulation. The aim of this study was to investigate whether it is possible to reduce the risk for exposure of microemboli by altering of the treatment mode. Twenty patients on chronic HD were randomized to a prospective cross‐over study of three modes of HD: (a) a dry‐stored dialyzer (F8HPS, Fresenius, steam sterilized) with a low blood level in the venous chamber (DL), (b) the same dialyzer as above, but with a high level in the venous chambe...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Ulf Forsberg, Per Jonsson, Christofer Stegmayr, Fredrik Jonsson, Bo Nilsson, Kristina Nilsson Ekdahl, Bernd Stegmayr Tags: Original Article Source Type: research

Kienböck's disease associated with radiocephalic fistula formation in a patient with end‐stage renal disease
Abstract Kienböck's disease, which consists of osteonecrosis and collapse of the lunate bone, causes chronic pain and dysfunction of the wrist. Patients on hemodialysis are occasionally present with wrist pain, but Kienböck's disease is rarely reported in dialysis patients. This case study describes Kienböck's disease in a patient with end‐stage renal disease on hemodialysis. A 39‐year‐old male with a 1‐year history of hemodialysis presented with left wrist pain that increased progressively over 6 months. The patient had no history of trauma or any other risk factors known to be associated with Kienb...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Gun Woo Kang, Da Young Lee, Young‐Hwan Lee, Ki Sung Ahn, Shin‐Kun Kim, In Hee Lee Tags: Case Report Source Type: research

The Argentine Society of Nephrology and the history of end‐stage renal disease in Argentina
(Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Carlos L. Blanco, Cristina Vallve Tags: Invited Preface Source Type: research

Evaluation of association between atherogenic index of plasma and intima‐media thickness of the carotid artery for subclinic atherosclerosis in patients on maintenance hemodialysis
Abstract Incidence of cardiovascular diseases in the patients having chronic kidney disease (CKD) is between 25% and 60%. This increased rate is proposed to be associated with “accelerated atherosclerosis.” Increased carotid intima‐media thickness (CIMT) is a subclinical atherosclerosis marker. Small‐dense low‐density lipoprotein particles are a strong risk factor for atherosclerosis. It was shown that atherogenic index of plasma (AIP = log(TG/HDL‐c)) is correlated with size of the lipoprotein particles. We investigated the correlation between AIP and CIMT which is a subclinical atheroscle...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Gürsel Yildiz, Alptekin Duman, Hüseyin Aydin, Abdulkerim Yilmaz, Ender Hür, Kemal Mağden, Gülay Çetin, Ferhan Candan Tags: Original Article Source Type: research

Antiangiogenic factors and maternal hemodynamics during intensive hemodialysis in pregnancy
We report on a 21‐year‐old pregnant patient with IgA nephropathy who was initiated on intensive hemodialysis (8 hours of hemodialysis 3 times a week) at a gestational age of 26 weeks on the basis of worsening kidney function resulting in rapidly progressive fatigue and difficulties in metabolic control. Throughout the pregnancy, and while on intensive hemodialysis, 24‐hour ambulatory blood pressure control was within the target, and results of weekly 24‐hour measurement of central hemodynamics and pulse wave velocity, and of serial levels of circulating (anti‐)angiogenic factors were comparable to normal pregnanc...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Tom Cornelis, Marc Spaanderman, Charles Beerenhout, Frank H. Perschel, Stefan Verlohren, Casper G. Schalkwijk, Frank M. Sande, Jeroen P. Kooman, Michelle Hladunewich Tags: Case Report Source Type: research

Excellent long time survival for Swedish patients starting home‐hemodialysis with and without subsequent renal transplantations
In this study, we report long‐term survival for patients starting home‐hemodialysis as first treatment and estimate the impact on survival of age, comorbidity, decade of start of home‐hemodialysis, sex, primary renal disease and subsequent renal transplantation. One hundred twenty‐eight patients starting home‐hemodialysis as first renal replacement therapy 1971–1998 in Lund were included. Data were collected from patient files, the Swedish Renal Registry and Swedish census. Survival analysis was made as intention‐to‐treat analysis (including survival after transplantation) and on‐dialysis‐treatment ...
Source: Hemodialysis International - April 1, 2013 Category: Hematology Authors: Helena Rydell, Lena Krützen, Ole Simonsen, Naomi Clyne, Mårten Segelmark Tags: Original Article Source Type: research

Coenzyme Q10 supplementation may improve diastolic heart functions especially coronary artery disease patients
(Source: Hemodialysis International)
Source: Hemodialysis International - March 25, 2013 Category: Hematology Authors: Sevket Balta, Sait Demırkol, Turgay Celik Tags: Letter to the Editor Source Type: research

Around the World with Nephrology: An Autobiography by Zbylut J. Twardowski, MD PhD
(Source: Hemodialysis International)
Source: Hemodialysis International - March 24, 2013 Category: Hematology Authors: Madhukar Misra Tags: Book Review Source Type: research

Platelet‐to‐lymphocyte ratio better predicts inflammation than neutrophil‐to‐lymphocyte ratio in end‐stage renal disease patients
Abstract Neutrophil‐to‐lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in end‐stage renal disease (ESRD) patients. Recently, platelet‐to‐lymphocyte ratio (PLR) and NLR were found to positively correlated with inflammatory markers including tumor necrosis factor‐α (TNF‐α) and interleukin (IL)‐6 in cardiac and noncardiac patients. Data regarding PLR and its association with inflammation are lacking in hemodialysis (HD) and peritoneal dialysis (PD) patients. Hence, we aimed to determine the relationship between PLR, NLR, and inflammation in ESRD patients. This ...
Source: Hemodialysis International - March 24, 2013 Category: Hematology Authors: Kultigin Turkmen, Fatih Mehmet Erdur, Fatih Ozcicek, Adalet Ozcicek, Emin Murat Akbas, Aysu Ozbicer, Levent Demirtas, Suleyman Turk, H. Zeki Tonbul Tags: Original Article Source Type: research

Determinants of training and technique failure in home hemodialysis
We examined characteristics of consecutive patients who initiated training for HHD between 2003 and 2011. Patients were classified as “failure” if they failed to complete HHD training or experienced technique failure (TF) within the first year of treatment. Remaining patients were classified as “success.” One hundred seventy‐seven patients initiated HHD training. In the “failure” group (n = 32), 24 did not finish training and 8 had TF. In the “success” group (n = 145), 65 (45%) patients remained on NHD, 49 (34%) discontinued HHD because of renal ...
Source: Hemodialysis International - March 17, 2013 Category: Hematology Authors: Michael E. Schachter, Karthik K. Tennankore, Christopher T. Chan Tags: Original Article Source Type: research

Effect of serum FGF‐23, MGP and fetuin‐A on calcium‐phosphate metabolism in maintenance hemodialysis patients
This study was aimed to explore the role of serum fibroblast growth factor (FGF)‐23, matrix Gla protein (MGP) and fetuin‐A in the calcium‐phosphate metabolism and their predicting value in coronary artery calcification in maintenance hemodialysis (MHD) patients. This study included 64 patients who receive hemodialysis in our hospital. The serum FGF‐23, MGP and fetuin‐A were analyzed by enzyme‐linked immunosorbent assay (ELlSA). Coronary artery calcification score (CACS) was evaluated by coronary artery computed tomography scan. The 64 patients (30 males, 34 females, 60.6 ± 11.3 years of age...
Source: Hemodialysis International - March 12, 2013 Category: Hematology Authors: Dong‐Mei Xiao, Qing Wu, Wei‐Feng Fan, Xian‐Wu Ye, Jian‐Ying Niu, Yong Gu Tags: Original Article Source Type: research

Association between antiinflammatory cytokine, IL‐10, and sleep quality in patients on maintenance hemodialysis
Abstract Elevated proinflammatory cytokines have been attributed to poor sleep quality in patients receiving hemodialysis. This is the first investigation about the relationship between sleep quality and circulating levels of antiinflammatory markers in these patients. A total of 72 patients who were receiving maintenance hemodialysis were enrolled in this cross‐sectional study. The Pittsburgh Sleep Quality Index (PSQI) was used to measure sleep quality. Patients were divided into two groups: good sleepers (PSQI score 
Source: Hemodialysis International - March 12, 2013 Category: Hematology Authors: Mohammad Taraz, Mohammad‐Reza Khatami, Maryam Hajiseyedjavadi, Amir Farrokhian, Mohsen Amini, Hossein Khalili, Alireza Abdollahi, Simin Dashti‐Khavidaki Tags: Original Article Source Type: research

Energy metabolism, body composition, and urea generation rate in hemodialysis patients
Abstract Hemodialysis (HD) adequacy is currently assessed using normalized urea clearance (Kt/V), although scaling based on Watson volume (V) may disadvantage women and men with low body weight. Alternative scaling factors such as resting energy expenditure and high metabolic rate organ mass have been suggested. The relationship between such factors and uremic toxin generation has not been established. We aimed to study the relationship between body size, energy metabolism, and urea generation rate. A cross‐sectional cohort of 166 HD patients was studied. Anthropometric measurements were carried on all. Resting energy ex...
Source: Hemodialysis International - March 11, 2013 Category: Hematology Authors: Sivakumar Sridharan, Enric Vilar, Jocelyn Berdeprado, Ken Farrington Tags: Original Article Source Type: research

Review of a new book on dialysis: Modeling and control of dialysis systems
(Source: Hemodialysis International)
Source: Hemodialysis International - March 6, 2013 Category: Hematology Authors: Zbylut J. Twardowski Tags: Book Review Source Type: research

An overlooked complication of hemodialysis: Hoarseness
Abstract In hemodialysis patients, some degree of transient hoarseness may occur at the end of the dialysis, and it may be a wearisome, recurrent, and severe state for some hemodialysis patients. However, to date, it has not been a well‐defined complication of hemodialysis. The aim of this study was to state this complication and to throw light on it. Four hundred fifty‐nine hemodialysis patients were questioned about any change in voice quality during hemodialysis. The patients who had this complaint (n = 70) were included in the study, and the group of patients who suffered hoarseness (subgroup 1: sever...
Source: Hemodialysis International - March 6, 2013 Category: Hematology Authors: Aysegul Zumrutdal Tags: Original Article Source Type: research

Lethal cardiac arrhythmia during central venous catheterization in a uremic patient: A case report and review of the literature
In conclusion, physicians responsible for CVC catheterization should pay more attention to patients with preexisting cardiac arrhythmia to prevent such technical mistakes from transpiring. (Source: Hemodialysis International)
Source: Hemodialysis International - March 6, 2013 Category: Hematology Authors: Ya‐Chin Huang, Jiun‐Chi Huang, Szu‐Chia Chen, Jer‐Ming Chang, Hung‐Chun Chen Tags: Case Report Source Type: research

Quality of water in hemodialysis centers in Baghdad, Iraq
Abstract Dialysis water quality is one of the important parameters all over the world because of its direct influence on the health of kidney patients. In Iraq, there are more than 20 dialysis centers; most of them contain identical units for the production of dialysis water. In this work, the quality of water used for dialysis in six dialysis centers located within Baghdad hospitals was evaluated. Samples of product water from each of the six dialysis centers were examined for total heterotrophic bacteria, endotoxin, and chemical contaminants. Endotoxin was measured on‐site using a portable instrument. Bacteriological a...
Source: Hemodialysis International - March 5, 2013 Category: Hematology Authors: Saadi K. Al‐Naseri, Zinah Mohammed Mahdi, Mohammed Fawzi Hashim Tags: Original Article Source Type: research

Diastolic dyssynchrony should be assessed as well as systolic dyssynchrony in patients with chronic kidney disease
(Source: Hemodialysis International)
Source: Hemodialysis International - March 5, 2013 Category: Hematology Authors: Sait Demirkol, Sevket Balta, Mustafa Cakar Tags: Letter to the Editor Source Type: research

Pseudoporphyria in a hemodialysis patient successfully treated with oral glutamine
(Source: Hemodialysis International)
Source: Hemodialysis International - March 5, 2013 Category: Hematology Authors: Alper Azak, Ezgi Yenigün, Gülay Koçak, Bülent Huddam, Bahar Kahve Tags: Letter to the Editor Source Type: research

What is the value of l‐carnitine level determination for carnitine supplementation in hemodialysis patients?
(Source: Hemodialysis International)
Source: Hemodialysis International - January 29, 2013 Category: Hematology Authors: Stephanie E. Reuter, Allan M. Evans Tags: Editorial Source Type: research

Serum coenzyme Q10 levels and coronary flow reserve in hemodialysis patients
(Source: Hemodialysis International)
Source: Hemodialysis International - January 24, 2013 Category: Hematology Authors: Sevket Balta, Sait Demırkol, Mustafa Cakar Tags: Letter to the Editor Source Type: research

2012 List of Reviewers
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Tags: 2012 List of Reviewers Source Type: research

Subject Index
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Tags: Indexes to Abstracts Source Type: research

Author Index
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Tags: Indexes to Abstracts Source Type: research

Hemodialysis Abstracts from the 33rd Annual Dialysis Conference 24th Annual Symposium on Pediatric Dialysis Seattle, Washington, March 9‐12, 2013
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Tags: Abstracts Source Type: research

Directory of Drug Dosage in Kidney Disease* (1st ed., 2011) by Günter Seyffart *Publisher: Dustri‐Verlag Dr. Karl Feistle GmbH & Co. KG, Munich‐Orlando. (US address: P.O. Box 561205, Rockledge, FL 32956‐1205, USA. http://www.dustri.com)
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Authors: Todd S. Ing Tags: Book Review Source Type: research

Preface
(Source: Hemodialysis International)
Source: Hemodialysis International - January 17, 2013 Category: Hematology Authors: Christopher R Blagg Tags: Preface Source Type: research

The flow field near a venous needle in hemodialysis: A computational study
In this study, the venous needle flow has been considered, using three‐dimensional computational methods. Four scenarios where the venous needle flow could potentially influence dialysis treatment outcome were identified and examined: Variation of the needle placement angle (10°, 20°, 30°), variation of the blood flow rate settings (200, 300, 400 mL/min), variation of the needle depth (top, middle, bottom), and the inclusion of a back eye in the needle design. The presence of the needle has significant effect on the flow field, with different scenarios having varying influence. In general, wall shear s...
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: David Fulker, Martin Kang, Anne Simmons, Tracie Barber Tags: Original Article Source Type: research

Arteriovenous fistula for the 80 years and older patients on hemodialysis: Is it worth it?
Abstract Over the last years, the proportion of patients older than 80 years with end‐stage renal disease has been constantly growing. Arteriovenous fistula (AVF) is known as the best vascular access for hemodialysis, but evidence for its added value is lacking for elderly. We retrospectively identified new vascular access (AVF and central venous catheter) created or installed between June 2005 and June 2008 in patients 80 years and older and in patients between 50 and 60 years. For every new AVF, we calculated primary failure, primary and secondary patency durations. Fifty‐five and 57 patients had a new vascular acces...
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: Annie‐Claire Nadeau‐Fredette, Rémi Goupil, Bernard Montreuil, Annie Carignan, Martine Leblanc Tags: Original Article Source Type: research

Challenges of providing maintenance hemodialysis in a resource poor country: Experience from a single teaching hospital in Lagos, Southwest Nigeria
Abstract Providing maintenance hemodialysis is associated with high costs and poor outcomes. In Nigeria, more than 90% of the population lives below the poverty line, and patients with end‐stage renal disease (ESRD) pay out‐of‐pocket for maintenance hemodialysis. To highlight the challenges of providing maintenance hemodialysis for patients with ESRD in Nigeria, we reviewed records of all patients who joined the maintenance hemodialysis program of our dialysis unit over a 21‐month period. Information regarding frequency of hemodialysis, types of vascular access for dialysis, mode of anemia treatment and frequency o...
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: Babawale T. Bello, Yemi R. Raji, Ibilola Sanusi, Rotimi W. Braimoh, Oluwatoyin C. Amira, Omolara M. Mabayoje Tags: Original Article Source Type: research

Volume estimation in dialysis patients: The concordance of brain‐type natriuretic peptide measurements and bioimpedance values
Abstract Correct estimation of the dialysis patients' hydration status remains an important clinical challenge. Bioimpedance measurements have been validated by various physiological tests, and the use of brain‐type natriuretic peptide (BNP) has been validated by inferior vena cava diameter measurements. This is an observational cohort study that evaluated the correspondence between bioimpedance‐measured overhydration percentage (OH%) and BNP. We measured predialysis OH% by bioimpedance apparatus (Body Composition Monitor) and BNP by microparticle enzyme‐linked immunoassay in 41 prevalent stable hemodialysis patients...
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: Mihály Tapolyai, Mária Faludi, Virág Réti, Zsolt Lengvárszky, Tibor Szarvas, Tibor Fülöp, Gabriella Bekő, Klára Berta Tags: Original Article Source Type: research

Coenzyme Q10 supplementation and diastolic heart functions in hemodialysis patients: A randomized double‐blind placebo‐controlled trial
Abstract Coenzyme Q10 (CoQ10) supplementation has been shown to improve diastolic heart function in various patient cohorts. Systolic and diastolic dysfunctions are common in patients with end‐stage renal disease. Favorable effects of CoQ10 on cardiac functions are yet to be seen in hemodialysis patients. We aimed to evaluate effect of CoQ10 supplementation on diastolic function in a cohort of maintenance hemodialysis patients. This was a prospective, double‐blind, placebo‐controlled, crossover study in which all patients received placebo and oral CoQ10 200 mg/d during the 8 weeks in each phase, with a 4‐wee...
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: Suleyman Turk, Aysegul Baki, Yalcin Solak, Mehmet Kayrak, Huseyin Atalay, Abduzhappar Gaipov, Alpay Aribas, Hakan Akilli, Zeynep Biyik, Nilsel Okudan, Hakki Gokbel Tags: Original Article Source Type: research

Case report: Atenolol overdose successfully treated with hemodialysis
In this report, a patient with impaired renal function was successfully treated with two 5‐hour intermittent high‐flux high‐efficiency hemodialysis therapies after atenolol overdose. Serial atenolol levels were measured during his hemodialysis treatments. We observed an over 50% plasma atenolol concentration reduction after each 5‐hour hemodialysis therapy. Hemodialysis therapy is an effective treatment for atenolol overdose, especially in patients with impaired renal function. (Source: Hemodialysis International)
Source: Hemodialysis International - January 1, 2013 Category: Hematology Authors: Shih‐Han S. Huang, Rommel G. Tirona, Cameron Ross, Rita S. Suri Tags: Case Report Source Type: research

Left ventricular mechanical dyssynchrony in patients with different stages of chronic kidney disease and the effects of hemodialysis
Abstract Left ventricular (LV) dyssynchrony is a known cause of mortality in patients with heart failure and may possibly play a similar role in patients with chronic kidney disease (CKD) in whom sudden death is one of the most common and as yet not fully explained cause of death. LV synchronicity and its relationship with increased volume load and various biomarkers was analyzed in 145 patients including 53 patients with CKD stages 3 and 4 and in 92 CKD stage 5 patients undergoing hemodialysis (HD) or peritoneal dialysis (PD) using color tissue Doppler imaging and tissue synchronization imaging. The HD patients were evalu...
Source: Hemodialysis International - October 1, 2012 Category: Hematology Authors: Shirley Yumi Hayashi, Jacek Nowak, Bengt Lindholm, Marcelo Mazza do Nascimento, Britta Lind, Anna Bjällmark, Matilda Larsson, Maria Aparecida Pachaly, Astrid Seeberger, Miguel C. Riella, Lars‐Åke Brodin Tags: Original Article Source Type: research