Elderly patients starting outpatient dialysis not at excessive mortality risk
(Source: Hemodialysis International)
Source: Hemodialysis International - July 10, 2014 Category: Hematology Authors: Steven M. Brunelli, Allen R. Nissenson, Mahesh Krishnan Tags: EDITORIAL Source Type: research

Karl D. Nolph, MD, FACP, FRCPS (Glasgow)
(Source: Hemodialysis International)
Source: Hemodialysis International - July 10, 2014 Category: Hematology Authors: Zbylut Twardowski, Madhukar Misra, Ramesh Khanna Tags: OBITUARY Source Type: research

Preface
(Source: Hemodialysis International)
Source: Hemodialysis International - July 10, 2014 Category: Hematology Authors: Christopher R. Blagg Tags: Preface Source Type: research

Effects of hemodialysis on ventricular activation time in children with end‐stage renal disease
Abstract Patients with end‐stage renal disease are affected by cardiovascular complications, including disturbances of the heart intraventricular conduction. Body surface potential mapping is a non‐invasive electrocardiographic detection method of initial disturbances in heart activation propagation. A goal of the study was to analyze the effects of single hemodialysis (HD) session on ventricular activation time (VAT) maps obtained from hemodialyzed children. The study group consisted of 13 hemodialyzed children (age: 6–18 years). The control group is composed of 26 healthy subjects. In each HD patient, 12‐lead...
Source: Hemodialysis International - July 3, 2014 Category: Hematology Authors: Krystyna Laszki‐Szcząchor, Dorota Polak‐Jonkisz, Danuta Zwolińska, Irena Makulska, Leopold Rehan, Małgorzata Sobieszczańska Tags: Original Article Source Type: research

Hemophagocytic lymphohistiocytosis: An unusual presentation of tuberculosis in hemodialysis patients
We report a series of three patients with end‐stage renal disease on maintenance hemodialysis presenting with hemophagocytic lymphohistiocytosis (HLH) as an unusual manifestation of extrapulmonary tuberculosis. All three patients were middle‐aged men. They presented with fever, pancytopenia, varying degrees of hepatosplenomegaly, abnormal liver function tests, coagulopathy, increased serum ferritin, and triglycerides. Tests for fever work‐up were negative. Bone marrow examination revealed hemophagocytosis and caseating granuloma. Acid fast bacilli were demonstrated in two patients. The HLH‐2004 diagnostic criteria ...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Sindhura L. Koulmane Laxminarayana, Shankar P. Nagaraju, Ravindra Prabhu Attur, Chethan Manohar, Rajeevalochana Parthasarathy, Brahmaiah Chari Tags: Case Report Source Type: research

Acute renal failure in a patient with mantle cell lymphoma
We present a 54‐year‐old gentleman with mantle cell lymphoma. It was diagnosed based on the demonstration of B‐cell antigens CD20 and CD5. It was further confirmed by demonstration of overexpression of cyclin D1 on these atypical lymphocytes in the immunohistochemical staining. He also had acute renal failure and proteinuria. Renal biopsy revealed crescents and lymphomatous infiltration of tubulointerstitium. The presence of infiltrating cells with similar markers in both the lymph node and the kidney confirmed the infiltration of kidney with lymphomatous cells. Our present patient, after a thorough literature search...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Sandeep Peddi, Rapur Ram, Sudheer Reddy Kataru, Krishna Kishore Chennu, Rukumangadha Nandyala, Radhika Kottu, V. Siva Kumar Tags: Case Report Source Type: research

Disseminated tuberculosis: A neglected entity in immunocompromised hemodialysis patients
We report an unusual case of an immunocompromised patient with a late diagnosis and delayed treatment of genitourinary tuberculosis that subsequently led to the diagnosis of vertebral and miliary tuberculosis (disseminating tuberculosis). Therefore, increased awareness is warranted from physicians dealing with hemodialysis patients in order to avoid delays in diagnosis and treatment initiation. (Source: Hemodialysis International)
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Eleni Gavriilaki, Nikos Sabanis, Eleni Paschou, Asterios Kalaitzoglou, Katerina Michalaki, Thomas Zarampoukas Tags: Case Report Source Type: research

Effect of alternate night nocturnal home hemodialysis on anemia control in patients with end‐stage renal disease
This study aims to investigate whether anemia and erythropoiesis‐stimulating agent (ESA) requirement are improved in patients receiving alternate night NHHD compared with conventional hemodialysis (CHD). In this retrospective controlled study, a clinical data of 23 patients receiving NHHD were compared with 25 in‐center CHD patients. Hemoglobin level, ESA requirement, iron profile, and dialysis adequacy indexes were compared between the two groups. Hemoglobin level increased from baseline of 9.37 ± 1.39 g/dL to 11.34 ± 2.41 g/dL at 24 months (P 
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Clara K. Y. Poon, Hon‐Lok Tang, Joseph H. S. Wong, Wai‐Ping Law, Chung‐Man Lam, Ka‐Fai Yim, Au Cheuk, William Lee, Ka‐Foon Chau, Matthew K. L. Tong, Samuel K. S. Fung Tags: Original Article Source Type: research

Weekly high‐dose ergocalciferol to correct vitamin D deficiency/insufficiency in hemodialysis patients: A pilot trial
Abstract Controversy exists on which vitamin D (D2 or D3) and which dosage scheme is the best to obtain and maintain adequate 25 OH D levels in dialysis patients safely. We tried to determine whether high‐dose vitamin D2 supplementation could obtain optimal vitamin D status without inducing hypercalcemia. We studied 82 patients on dialysis not taking active vitamin D therapy and supplemented them with oral vitamin D2 72,000 IU/week for 12 weeks followed by 24,000 IU/week as maintenance therapy during 36 weeks. By week 12, serum 25(OH)D increased from 15.2 ± 5.4 to 42.5 ±&t...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Elisa Del Valle, Armando L. Negri, Erich Fradinger, Manuel Canalis, Pablo Bevione, Maria Curcelegui, Marina Bravo, Marcelo Puddu, Alicia Marini, Jaime Ryba, Patricia Peri, Guillermo Rosa Diez, Luis Sintado, Eduardo Gottlieb Tags: Original Article Source Type: research

Effect of dialysis dose and membrane flux on hemoglobin cycling in hemodialysis patients
Abstract Many studies found that hemoglobin (Hb) fluctuation was closely related to the prognosis of the maintenance hemodialysis patients. We investigated the association of factors relating dialysis dose and dialyzer membrane with Hb levels. We undertook a randomized clinical trial in 140 patients undergoing thrice‐weekly dialysis and assigned patients randomly to a standard or high dose of dialysis; Hb level was measured every month for 12 months. In the standard‐dose group, the mean (±SD) urea reduction ratio was 65.1% ± 7.3%, the single‐pool Kt/V was 1.26 ± 0.11, ...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Liyu He, Min Fu, Xian Chen, Hong Liu, Xing Chen, Xiaofei Peng, Fuyou Liu, Youming Peng Tags: Original Article Source Type: research

Occult hepatitis B virus infection of hemodialysis patients: A cross‐sectional study in a hepatitis B virus‐endemic region
Abstract Occult hepatitis B virus (HBV) infection is defined as the presence of HBV DNA in the liver tissue and/or serum of subjects seronegative for hepatitis B surface antigen (HBsAg). Occult HBV infection of hemodialysis (HD) patients is informative in terms of virus transmission, reactivation after kidney transplantation, and the progression of liver disease. However, there is little detailed information about occult HBV infection in the context of virus endemicity. We tried to investigate the seroprevalence and clinical features of occult HBV infection in HD patients in HBV‐endemic regions. We enrolled a total of 15...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: So Mi Kim, Hyun Woo Kim, Ji Eun Lee, Eun Kyoung Lee, Hyun Deok Shin, Il Han Song Tags: Original Article Source Type: research

Highest serum creatinine ever reported in a child
(Source: Hemodialysis International)
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Gyongyi Okechuku, Kiran K Upadhyay Tags: Letter to the Editor Source Type: research

Cerebral microbleeds and cognitive decline in a hemodialysis patient: Case report and review of literature
We present an ESRD patient on chronic hemodialysis with a history of gradual cognitive decline and progressive CMBs. Through this case and literature review, we illustrate the need to develop detection and prediction models to treat this frequent development in ESRD patients. (Source: Hemodialysis International)
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Lin Li, Mark Fisher, Wei‐Ling Lau, Hamid Moradi, Alexander Cheung, Gaby Thai, Jason Handwerker, Kamyar Kalantar‐Zadeh Tags: Case Report Source Type: research

Can primary failure of arteriovenous fistulas be anticipated?
Abstract Primary failure, early thrombosis, and inadequate maturation are the main complications encountered in arteriovenous fistulas. Doppler ultrasonographic assessment of flow‐mediated dilatation (FMD) is currently used for the early diagnosis of atherosclerosis. Clinical experience in the use of FMD for preoperative assessment of vasculature is rather limited; therefore, we sought to elucidate the relationship between preoperative FMD and primary failure of the fistula. Thirty‐three patients with end‐stage renal disease who were admitted to our hospital between January and July 2005 were included in our study. M...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Dilek Gibyeli Genek, Canan Tuncer Altay, Tarkan Unek, Aykut Sifil, Mustafa Seçil, Taner Camsari Tags: Original Article Source Type: research

Intracerebral hemorrhage was the highest cause of mortality among stroke subtypes in Japanese dialysis patients
(Source: Hemodialysis International)
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Minako Wakasugi, Junichiro J. Kazama, Ichiei Narita Tags: Letter to the Editor Source Type: research

Survey of home hemodialysis patients and nursing staff regarding vascular access use and care
Abstract Vascular access infections are of concern to hemodialysis patients and nurses. Best demonstrated practices (BDPs) have not been developed for home hemodialysis (HHD) access use, but there have been generally accepted practices (GAPs) endorsed by dialysis professionals. We developed a survey to gather information about training provided and actual practices of HHD patients using the NxStage System One HHD machine. We used GAP to assess training used by nurses to teach HHD access care and then assess actual practice (adherence) by HHD patients. We also assessed training and adherence where GAPs do not exist. We rece...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Leslie A. Spry, John M. Burkart, Christina Holcroft, Leigh Mortier, Joel D. Glickman Tags: Original Article Source Type: research

Balloon inflation time in angioplasty of dialysis access stenosis
(Source: Hemodialysis International)
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Brendon L. Neuen, Frank Grainer, Murty L. Mantha Tags: Letter to the Editor Source Type: research

Role of turmeric in oxidative modulation in end‐stage renal disease patients
This study was a prospective and double‐blind randomized clinical trial. Fifty HD patients aged 18–60 years were recruited after fulfilling the inclusion criteria. Patients were randomly categorized into 2 groups: trial group received turmeric and control group received placebo for 8 weeks. Each patient in the trial group received turmeric, whereas the control group received starch for the same 8 weeks. Plasma malondialdehyde (MDA), red blood cell (RBC) antioxidant enzyme activities as glutathione peroxidase (GPX), glutathione reductase (GR), and catalase (CAT), cholesterol, high‐density lipoprotein‐cholesterol...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Maryam Pakfetrat, Masoumeh Akmali, Leila Malekmakan, Mojtaba Dabaghimanesh, Marjan Khorsand Tags: Original Article Source Type: research

Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient
This report demonstrates the difficulty in correctly diagnosing local hepatic TB. We report the case of a 62‐year‐old male patient with end‐stage renal disease treated with hemodialysis, who developed 2 months of abdominal distension and general anorexia, with hyperechoic hepatic lesions on ultrasound. Computed tomography suspected multiple liver tumors. The liver biopsy finally led to the diagnosis of TB of the liver without other involvements. We conclude that isolated hepatic TB is one of the rare forms of extrapulmonary TB in dialysis patients. A greater awareness of this rare clinical entity may prevent needless...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Yao‐Min Hung, Neng‐Chyan Huang, Jyh‐Seng Wang, Shue‐Ren Wann Tags: Case Report Source Type: research

Patient‐reported cognitive functioning and daily functioning in chronic dialysis patients
Abstract Subjective cognitive impairment negatively affects daily functioning, health‐related quality of life, and health care consumption, and is predictive of future cognitive decline in many patient populations. However, no subjective measures of multidimensional cognitive functioning have been evaluated for dialysis patients. Our purposes were to examine (1) the association between patient‐reported (subjective) cognitive functioning and objective cognitive functioning and (2) the relationships between subjective and objective cognitive functioning and everyday functioning of dialysis patients. We used baseline data...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Mi‐Kyung Song, Sandra E. Ward, Eric Bair, Lia J. Weiner, Jessica C. Bridgman, Gerald A. Hladik, Constance A. Gilet Tags: Original Article Source Type: research

Piperacillin/tazobactam‐induced neurotoxicity in a hemodialysis patient: A case report
This report presents a case of a hypertensive and diabetic 67‐year‐old woman in regular hemodialysis, which previously had a stroke. She was hospitalized presenting pneumonia, which was initially treated with cefepime. Two days after treatment, she presented dysarthria, left hemiparesis, ataxia, and IX and X cranial nerves paresis. Computed tomography showed no acute lesions and cefepime neurotoxicity was hypothesized, and the antibiotic was replaced by piperacillin/tazobactam. The neurologic signs disappeared; however, 4 days after with piperacillin/tazobactam treatment, the neurological manifestations returned. A new...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Precil Diego M. M. Neves, Fernanda M. Freitas, Christiane A. Kojima, Beatriz L. Carmello, Rodrigo Bazan, Pasqual Barretti, Luis C. Martin Tags: Case Report Source Type: research

The perspectives of Aboriginal patients and their health care providers on improving the quality of hemodialysis services: A qualitative study
This study aims to describe and analyze the perspectives of Aboriginal patients' and health care providers' experience of renal services, to inform service improvement for rural Aboriginal hemodialysis patients. We conducted a thematic analysis of interviews with Aboriginal patients (n = 18) receiving hemodialysis in rural Australia and health care providers involved in their care (n = 29). An overarching theme of avoiding the “costly” crisis encompassed four subthemes: (1) Engaging patients earlier (prevent late diagnosis, slow disease progression); (2) flexible family‐focused car...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Elizabeth F. Rix, Lesley Barclay, Janelle Stirling, Allison Tong, Shawn Wilson Tags: Original Article Source Type: research

Association between depression and inflammatory/anti‐inflammatory cytokines in chronic kidney disease and end‐stage renal disease patients: A review of literature
Abstract Depression is a common psychiatric disorder in patients with advanced chronic kidney diseases (CKDs). Strong correlation has been reported between depression and patients' morbidity and mortality among dialysis patients. On the contrary, chronic inflammation may be a major contributor to morbidity and mortality in these patients. Elevated plasma levels of proinflammatory cytokines, especially C‐reactive protein and interleukin (IL)‐6, have been correlated with cardiovascular events, hospitalization, and all‐cause and cardiovascular‐associated mortality in dialysis patients. Studies suggested that inflammat...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Mohammad Taraz, Saeideh Taraz, Simin Dashti‐Khavidaki Tags: Review Article Source Type: research

Iliopsoas abscess as a complication of tunneled jugular vein catheterization in a hemodialysis patient
Abstract Iliopsoas abscess is a rare complication in hemodialysis patients that is mainly due to adjacent catheterization, local acupuncture, discitis, and bacteremia. Herein, we report a 47‐year‐old woman undergoing regular hemodialysis via a catheter in the internal jugular vein who presented with low back pain and dyspnea. A heart murmur suggested the presence of catheter‐related endocarditis, and this was confirmed by an echocardiogram and a blood culture of methicillin‐resistant Staphylococcus aureus. A computed tomography indicated a pulmonary embolism and an incidental finding of iliopsoas abscess. Following...
Source: Hemodialysis International - July 1, 2014 Category: Hematology Authors: Po‐Jen Hsiao, Ming‐Hsien Tsai, Jyh‐Gang Leu, Yu‐Wei Fang Tags: Case Report Source Type: research

A case of anaphylactic shock induced by FX60 polysulfone hemodialyzer but not F6‐HPS polysulfone hemodialyzer
Abstract A 75‐year‐old woman was admitted for dyspnea and fever. She underwent emergent dialysis smoothly under F6‐HPS polysulfone hemodialyzer. With two subsequent hemodialysis sessions, severe anaphylactic reaction with cardiopulmonary resuscitation occurred under FX60 polysulfone dialyzer. Further dialysis sessions by F6‐HPS polysulfone dialyzer were uneventful. This rare case demonstrated that dialyzer reaction may be markedly different even with the same material and the same manufacturer. (Source: Hemodialysis International)
Source: Hemodialysis International - June 13, 2014 Category: Hematology Authors: Kai‐Hsiang Shu, Tze‐Wah Kao, Wen‐Chih Chiang, Vin‐Cent Wu Tags: Case Report Source Type: research

Association of anxiety, sleepiness, and sexual dysfunction with restless legs syndrome in hemodialysis patients
Abstract Restless legs syndrome (RLS) is characterized by unpleasant sensations, pain in the legs along with irresistible urges to move the legs when at rest. It is often accompanied by sleep disturbance. The purpose of this study was to assess the association of anxiety and sleepiness with sexual function in hemodialysis patients with and without RLS. Sociodemographic parameters, laboratory data of hemodialysis patients from three dialysis centers were collected prospectively. Anxiety, sleepiness, sexual function, and presence of RLS symptoms were assessed with standardized questionnaires as the RLS Diagnosis and Scale, H...
Source: Hemodialysis International - May 28, 2014 Category: Hematology Authors: Suber Dikici, Anzel Bahadir, Davut Baltaci, Handan Ankarali, Mustafa Eroglu, Nurten Ercan, Tansu Sav Tags: Article Source Type: research

Barriers, biases, and beliefs about arteriovenous fistula placement in children: A survey of the International Pediatric Fistula First Initiative (IPFFI) within the Midwest Pediatric Nephrology Consortium (MWPNC)
Abstract There has been recent emphasis on increased arteriovenous fistula (AVF) use and decreased central venous catheter use in hemodialysis (HD) patients. The International Pediatric Fistula First Initiative was founded via collaborative effort with the Midwest Pediatric Nephrology Consortium to alert nephrologists, surgeons, and dialysis staff to consider fistulae as the best access in pediatric HD patients. A multidisciplinary educational DVD outlining expectations and strategies to increase AVF placement and usage in children was created. Participants were administered a survey previewing and postviewing to identify ...
Source: Hemodialysis International - May 28, 2014 Category: Hematology Authors: Deepa H. Chand, Denis Geary, Hiren Patel, Larry A. Greenbaum, Corina Nailescu, Michael E. Brier, Rudolph P. Valentini Tags: Original Article Source Type: research

Effect of hemodiafiltration with endogenous reinfusion on overt idiopathic chronic inflammation in maintenance hemodialysis patients: A multicenter longitudinal study
Abstract Chronic inflammation is widely diffuse in maintenance hemodialysis (MHD) patients and is associated with poor survival. Hemodiafiltration with endogenous reinfusion (HFR) is a dialysis technique, highly biocompatible, able to adsorb proinflammatory cytokines and to decrease amino acids and antioxidants loss. These features could be helpful in MHD patients affected by idiopathic chronic inflammation, but this issue remains to be elucidated. We performed a multicenter longitudinal study to assess the effect of the switching from bicarbonate HD to HFR in patients with serum C‐reactive Protein (CRP) >&thin...
Source: Hemodialysis International - May 28, 2014 Category: Hematology Authors: Silvio Borrelli, Roberto Minutolo, Luca De Nicola, Emanuele De Simone, Walter De Simone, Bruno Zito, Pasquale Guastaferro, Filippo Nigro, Giuseppe Iulianiello, Olga Credendino, Antonio Bassi, Luigi Leone, Maria Capuano, Maria Rita Auricchio, Giuseppe Cont Tags: Original Article Source Type: research

Effects of enoxaparin on myeloperoxidase release during hemodialysis
Abstract Myeloperoxidase (MPO) is a proteolytic and prooxidant enzyme largely assembled with the vascular wall, and a heparin‐binding protein. We studied if low‐molecular‐weight heparin enoxaparin administered for hemodialysis (HD) anticoagulation causes systemic MPO activation. Plasma MPO levels were measured in patients undergoing maintenance HD with an intravenous bolus of enoxaparin. Patients were retested during HD employing dialyzers with heparin‐grafted polyacrylonitrile membrane and no systemic enoxaparin administration. During enoxaparin‐anticoagulated HD plasma MPO levels strikingly increased in all pat...
Source: Hemodialysis International - May 19, 2014 Category: Hematology Authors: Joanna Gozdzikiewicz, Jacek Borawski, Ewa Koc‐Zorawska, Michal Mysliwiec Tags: Original Article Source Type: research

Survival and other clinical outcomes of maintenance hemodialysis patients in Taiwan: A 5‐year multicenter follow‐up study
Abstract The increasing aging and diabetes mellitus (DM) patients in dialysis population make the quality maintenance of dialysis an imperative issue. Recently, an increasing number of dialysis centers were run by private dialysis providers, many of which apply quality assurance programs and performance management systems to dialysis care. We studied patients in dialysis facilities in Taiwan run by a private chain to see clinical outcomes of centers operating under these systemic strategies. Hemodialysis patients from January 1, 2008 to December 31, 2012 in 25 dialysis facilities in Taiwan, which received the management an...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Huan‐Sheng Chen, Chun‐Ting Cheng, Chun‐Cheng Hou, Hung‐Hsiang Liou, Paik‐Seong Lim Tags: Original Article Source Type: research

Pruritus in hemodialysis patients: Results from the Japanese Dialysis Outcomes and Practice Patterns Study (JDOPPS)
In this study, pruritus and its relationship to morbidity, quality of life (QoL), sleep quality, and patient laboratory measures were analyzed in a large sample of Japanese patients undergoing HD. Severity of patient‐reported pruritus symptoms experienced during a 4‐week period was collected from 6480 Japanese patients undergoing HD in three phases of the Dialysis Outcomes and Practice Patterns Study (DOPPS; 1996–2008; 60–65 study facilities/phase). Adjusted linear and logistic regressions were used to identify associations of pruritus with treatment parameters and QoL outcomes. Adjusted Cox regressions exa...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Naoki Kimata, Douglas S. Fuller, Akira Saito, Tadao Akizawa, Shunichi Fukuhara, Ronald L. Pisoni, Bruce M. Robinson, Takashi Akiba Tags: Original Article Source Type: research

Physical examination of arteriovenous fistula: The influence of professional experience in the detection of complications
Abstract Vascular access is one of the leading causes of mobilization of financial resources in health systems for people with chronic kidney disease on hemodialysis. Physical examination of the arteriovenous fistula (AVF) has demonstrated its effectiveness in identifying complications. We decided to evaluate the influence of nurses' professional experience in the detection of complications of the AVF (venous stenosis and steal syndrome). The study took place in eight hemodialysis centers between May and September of 2011 in the north of Portugal. Sample was constituted by registered nurses. The nurses involved in the expe...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Clemente Neves Sousa, Paulo Teles, Vanessa Filipa Ferreira Dias, João Luís Alves Apóstolo, Maria Henriqueta Jesus Silva Figueiredo, Maria Manuela Martins Tags: Original Article Source Type: research

Hemodialysis‐related headache
Abstract Headache is one of the most frequently encountered neurological symptoms during hemodialysis. According to International Classification of Headache criteria dialysis‐related headache was defined as the headache occurring during hemodialysis with no specific characteristic. It resolves spontaneously within 72 hours after the hemodialysis session ends. There are few studies in the literature investigating the clinical features of dialysis headache. The pathophysiology of hemodialysis‐related headache is not known, but various triggering factors have been identified, including changes in blood pressure, serum sod...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Murat Yusuf Sav, Tansu Sav, Elif Senocak, Nadide Melike Sav Tags: Review Article Source Type: research

Clearance of myoglobin by high cutoff continuous veno‐venous hemodialysis in a patient with rhabdomyolysis: A case report
Abstract Continuous veno‐venous hemodialysis using high cutoff filters (HCO‐CVVHD) is a promising technique, which may be effective to decrease the extremely high level of circulating myoglobin in patients with rhabdomyolysis (RM). Here, we report a patient with RM caused by heat stroke who was successfully treated by HCO‐CVVHD. A male patient received HCO‐CVVHD with 4 L/h dialysate for 5 days and then pre‐dilution continuous veno‐venous hemofiltration (CVVH) at a dose of 4 L/h until recovery of renal function. The clearance of myoglobin and albumin at 5 minutes, and at 4, 12, and 24 hours were ca...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Bunyun Wu, Dehua Gong, Daxi Ji, Bin Xu, Zhihong Liu Tags: Case Report Source Type: research

Hemodialysis for infants, children, and adolescents
Abstract Children with chronic kidney disease stage 5 requiring dialysis can be treated by peritoneal or hemodialysis. In the United Kingdom nearly twice as many children receive peritoneal dialysis compared with hemodialysis. Technical aspects of pediatric hemodialysis are challenging and include the relative size of extracorporeal circuit and child's blood volume, assessment of adequacy,technical and complications of vascular access. Alternatives to standard hospital‐based hemodialysis are also increasingly available. Optimizing nutritional status with the support of specialist pediatric dietitians is key to the manage...
Source: Hemodialysis International - April 14, 2014 Category: Hematology Authors: Amrit Kaur, Andrew Davenport Tags: Review Article Source Type: research

Stanley Shaldon: 1931–2013
(Source: Hemodialysis International)
Source: Hemodialysis International - April 2, 2014 Category: Hematology Authors: Angus Rae Tags: OBITUARY Source Type: research

Please, take X‐ray!
(Source: Hemodialysis International)
Source: Hemodialysis International - April 2, 2014 Category: Hematology Authors: Ewa Weber, Wojciech Wołyniec, Tomasz Liberek Tags: LETTER TO THE EDITOR Source Type: research

Preface
(Source: Hemodialysis International)
Source: Hemodialysis International - April 2, 2014 Category: Hematology Authors: Christopher R. Blagg Tags: Preface Source Type: research

Iatrogenic or congenital arteriovenous fistula of left upper arm used for hemodialysis after venous superficialization
Abstract The authors report a case of iatrogenic brachial arteriovenous fistula (AVF) on the left arm in a 20‐year‐old man with a history of autosomal dominant polycystic kidney and failing kidney transplant. An attempt to create vascular access for hemodialysis by utilization of an existing iatrogenic brachial AVF was undertaken. The patient underwent surgical superficialization of a concomitant enlarged and deeply located vein. Four weeks after the procedure, the AVF was successfully cannulated for hemodialysis. In this case, iatrogenic/congenital AVF was successfully converted to vascular access for hemodialysis. (S...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Mariusz Kusztal, Krzysztof Letachowicz, Tomasz Gołębiowski, Ewa Wątorek, Przemysław Szyber, Jerzy Garcarek, Wacław Weyde, Marian Klinger Tags: Case Report Source Type: research

Phosphate binders and metabolic acidosis in patients undergoing maintenance hemodialysis—sevelamer hydrochloride, calcium carbonate, and bixalomer
We examined 12 of the 122 consecutive Japanese patients with end‐stage renal disease on HD, who orally ingested a dose of SH (≥2250 mg), and an arterial blood gas analysis and biochemical analysis were performed before HD. Patients whose serum HCO3– levels were under 18 mmol/L were changed from SH to the same dose of bixalomer. A total of 12 patients were treated with a large amount of SH. Metabolic acidosis (a serum HCO3– level under 18 mmol/L) was found in eight patients. These patients were also treated with or without small dose of calcium carbonate (1.2 ± 1.1&...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Toru Sanai, Hideo Tada, Takashi Ono, Toma Fukumitsu Tags: Original Article Source Type: research

Pyogenic liver abscess in end‐stage renal disease patients: A nationwide longitudinal study
Abstract End‐stage renal disease (ESRD) patients are more prone to infectious disease because of their immunocompromised status. However, the association between pyogenic liver abscess (PLA) and ESRD remains not clear. The aim of our study is to evaluate the incidence, risk factors, and outcomes of PLA in ESRD patients. We recruited all incident ESRD patients from the Taiwan National Health Insurance database from 1998 to 2006. The incidence rate of PLA in ESRD patients was compared with that of a randomly selected non‐ESRD control group matched for age, sex gender, Charlson comorbidity score, diabetes mellitus, and ci...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Lung‐Wen Tsai, Pei‐Wen Chao, Shuo‐Ming Ou, Yung‐Tai Chen, Chia‐Jen Shih, Szu‐Yuan Li, Tzen‐Wen Chen, Tzeng‐Ji Chen, Chien‐Tsai Liu Tags: Original Article Source Type: research

Association of increased travel distance to dialysis units with the risk of anemia in rural chronic hemodialysis elderly
Abstract Geographic remoteness has been found to influence health‐related outcomes negatively. As reported in the literature, rural dialysis patients have a higher risk of mortality with increasing travel distance to dialysis units. However, few studies have focused on the impact of travel distances on the development of dialysis complications. We utilized a prospectively collected chronic hemodialysis patient cohort from a rural regional hospital for analysis. Data on demographics, comorbidities, and serum laboratory results were obtained. Correlation analyses between travel distance to dialysis units and dialysis compl...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Chia‐Ter Chao, Chun‐Fu Lai, Jenq‐Wen Huang, Chih‐Kang Chiang, Sheng‐Jen Huang Tags: Original Article Source Type: research

Erythropoietin‐stimulating agents in the management of anemia of end‐stage renal disease patients on regular hemodialysis: A prospective randomized comparative study from Qatar
This study has specifically compared the effect of ESA type on the variability of serum hemoglobin levels in hemodialysis patients. Furthermore, it confirmed the efficacy and safety of once monthly CERA for maintaining tight hemoglobin control within recommended target ranges. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Fadwa Saqr Al‐Ali, Mohamed El‐Sayed Abdelfattah, Ashraf Ahmed Fawzy, Ahmed Farouk Hamdy, Aisha Elsayed Abdulla Tags: Original Article Source Type: research

Dialysis access venous stenosis: Treatment with balloon angioplasty 30‐second vs. 1‐minute inflation times
Abstract Percutaneous balloon angioplasty is the standard of care in the endovascular treatment of dialysis access venous stenosis. The significance of balloon inflation times in the treatment of these stenoses is not well defined. Our objective was to examine the outcomes of 30‐second vs. 1‐minute balloon inflation times on primary‐assisted patency of arteriovenous fistulae and grafts. Using a prospectively collected vascular access database, we identified a total of 75 patients referred for access dysfunction during a 5‐year period. These patients received 223 interventions (178 with 30‐second inflations and 45...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Mohsen Elramah, Lamya Boujelbane, Alexander S. Yevzlin, Maureen Wakeen, Brad C. Astor, Micah R. Chan Tags: Original Article Source Type: research

Assessment of subjective and hemodynamic tolerance of different high‐ and low‐flux dialysis membranes in patients undergoing chronic intermittent hemodialysis: A randomized controlled trial
Abstract Clinical experience and experimental data suggest that intradialytic hemodynamic profiles could be influenced by the characteristics of the dialysis membranes. Even within the worldwide used polysulfone family, intolerance to specific membranes was occasionally evoked. The aim of this study was to compare hemodynamically some of the commonly used polysulfone dialyzers in Switzerland. We performed an open‐label, randomized, cross‐over trial, including 25 hemodialysis patients. Four polysulfone dialyzers, A (Revaclear high‐flux, Gambro, Stockholm, Sweden), B (Helixone high‐flux, Fresenius), C (Xevonta high...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Giorgia Bianchi, Vanja Salvadé, Barbara Lucchini, Sibylle Schätti‐Stählin, Igor Salvadé, Michel Burnier, Luca Gabutti Tags: Original Article Source Type: research

Central vein perforation during tunneled dialysis catheter insertion: Principles of acute management
Abstract Central venous perforation during dialysis catheter insertion is a potentially fatal complication. Prompt recognition and judicious initial steps are important in optimizing the outcome. The purpose of this manuscript is to illustrate the imaging features and steps in initial management. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Uei Pua Tags: Case Report Source Type: research

Home hemodialysis: Beliefs, attitudes, and practice patterns
Abstract There is increasing interest of the worldwide kidney community in home hemodialysis (HHD). This is due to emerging evidence of its superiority over conventional hemodialysis (HD), largely attributed to improved outcomes on intensive schedule HD, best deployed in patient's own homes. Despite published work in this area, universal uptake remains limited and reasons are poorly understood. All those who provide HD care were invited to participate in a survey on HHD, initiated to understand the beliefs, attitudes, and practice patterns of providers offering this therapy. The survey was developed and posted on the Nephr...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Anuradha Jayanti, Julie Morris, Peter Stenvinkel, Sandip Mitra Tags: Original Article Source Type: research

Tailoring dialysis and resuming low‐protein diets may favor chronic dialysis discontinuation: Report on three cases
This report describes three patients with RFR who were recently treated at a new dialysis unit set up to offer intensive hemodialysis. All three patients were females, aged 73, 75, and 78 years. Kidney disease included vascular‐cholesterol emboli, diabetic nephropathy and vascular and dysmetabolic disease. At time of RFR, the patients had been dialysis‐dependent from 3 months to 1 year. Dialysis was started with different schedules and was progressively discontinued with a “decremental” policy, progressively decreasing number and duration of the sessions. A moderately restricted low‐protein diet (proteins...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Giorgina Barbara Piccoli, Gabriella Guzzo, Federica Neve Vigotti, Irene Capizzi, Roberta Clari, Stefania Scognamiglio, Valentina Consiglio, Emiliano Aroasio, Silvana Gonella, Andrea Veltri, Paolo Avagnina Tags: Case Report Source Type: research

Inflammation, high ferritin, and erythropoietin resistance in indigenous maintenance hemodialysis patients from the Top End of Northern Australia
This study aimed to explore the relationship among iron studies, inflammation, ESA responsiveness, and ESAs and iron requirements in indigenous patients on MHD from the Top End of Northern Australia. We performed a retrospective cohort analysis of anemia management in a cohort of our patients on MHD. We extracted data for 178 indigenous and 19 non‐indigenous patients from 1 March 2009 to 28 February 2010 from the Renal Anaemia Management database, which collects data prospectively in MHD patients. Ninety‐nine percent of the whole sample had a ferritin level above the international guidelines threshold of>500 ...
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Sandawana William Majoni, Joy‐Anne Ellis, Heather Hall, Asanga Abeyaratne, Paul D. Lawton Tags: Original Article Source Type: research

Bile cast nephropathy: An often forgotten diagnosis
We present a case wherein an alcoholic patient presented with high bilirubin levels and anuric acute kidney injury. The initial urine analysis suggested intrinsic renal disease. A kidney biopsy, performed a few days after the initiation of dialysis, demonstrated the presence of bile casts along with acute tubular injury. The patient however continued to be dialysis dependent inspite of initiating prednisolone to treat acute alcoholic hepatitis. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2014 Category: Hematology Authors: Adrian Sequeira, Xin Gu Tags: Case Report Source Type: research