Enterococcus faecalis endophthalmitis as a metastatic complication of hemodialysis vascular access‐related sepsis: A case report and review of the literature
Abstract Catheter and/or arteriovenous (A‐V) graft‐related bacteremia is an important cause of morbidity and mortality among hemodialysis (HD) patients. Endocarditis, septic arthritis, epidural abscess, septic embolism, and osteomyelitis are the most common complications of catheter and/or A‐V graft‐related bacteremia; however, endogenous endophthalmitis is rarely seen. To the best of our knowledge, Enterococcus faecalis is the first case report in this population. We hereby report a case of endogenous endophthalmitis caused by E. faecalis as a complication of catheter and/or A‐V graft‐related bacteremia...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Osman Zikrullah Sahin, Ekrem Kara, Tahir Belice, Teslime Ayaz, Serap Baydur Sahin, Cinar Ozturk, Safak Yildirim, Yavuz Metin, Tuncay Sahutoglu Tags: Review Article Source Type: research

Sequential molecularly targeted drug therapy including axitinib for a patient with end‐stage renal failure and metastatic renal cell carcinoma
Abstract A 62‐year‐old male patient with end‐stage renal disease and metastatic renal cell carcinoma (RCC) was referred to our hospital. Sequential targeted therapy consisting of sorafenib, sunitinib, and everolimus was administered, but the patient's disease gradually progressed. Axitinib was subsequently administered at a decreased dose of 6 mg/day for 2 weeks, after which the dose was escalated to 10 mg/day. Axitinib therapy was maintained for a total of 6 months without severe adverse effects. Sequential molecularly targeted drug therapy including axitinib, with careful monitoring, is one possible t...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Hayato Nishida, Hiroki Fukuhara, Atsushi Yamagishi, Toshihiko Sakurai, Tomohiro Shibasaki, Hisashi Kawazoe, Tomoyuki Kato, Yoshihiko Tomita Tags: Case Report Source Type: research

Carnitine deficiency in children receiving continuous renal replacement therapy
Abstract Carnitine deficiency is known to occur in chronic hemodialysis; however, the effect of continuous renal replacement therapy (CRRT) on carnitine homeostasis has not been studied. We hypothesized that children receiving CRRT are at risk for deficiency because of continuous removal, absent intake, decreased production, and comorbidities related to critical illness. Records of patients with acute kidney injury receiving CRRT at Children's National Health System between 2011 and 2014 were reviewed for total carnitine (TC), free carnitine (FC), feeding modality, severity of illness, and survival outcome. The proportion ...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Kristen Sgambat, Asha Moudgil Tags: Original Article Source Type: research

Calculation of the clearance requirements for the development of a hemodialysis‐based wearable artificial kidney
Abstract Wearable artificial kidney (WAK) has been considered an alternative to standard hemodialysis (HD) for many years. Although various novel WAK systems have been recently developed for use in clinical applications, the target performance or standard dose of dialysis has not yet been determined. To calculate the appropriate clearance for a HD‐based WAK system for the treatment of patients with end‐stage renal disease with various dialysis conditions, a classic variable–volume two‐compartment kinetic model was used to simulate an anuric patient with variable target time‐averaged creatinine concentration (...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Dong Ki Kim, Jung Chan Lee, Hajeong Lee, Kwon Wook Joo, Kook‐Hwan Oh, Yon Su Kim, Hyung‐Jin Yoon, Hee Chan Kim Tags: Original Article Source Type: research

“You know your own fistula, it becomes a part of you”—Patient perspectives on vascular access: A semistructured interview study
This study aims to describe patient perspectives on vascular access. Face‐to‐face, semistructured interviews were conducted with 26 adult patients receiving hemodialysis with any form of vascular access at two dialysis units in Australia. The transcripts were analyzed using thematic analysis. We identified five major themes describing patient perspectives on vascular access: developing mental fortitude for access (accepting necessity for survival, self‐advocacy, experiential confidence and competency, dependency on others, gaining vascular knowledge), device intrusiveness on the body (restricting normal function, fin...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Matthew J. Taylor, Camilla S. Hanson, Jordan R. Casey, Jonathan C. Craig, David Harris, Allison Tong Tags: Original Article Source Type: research

Risk of major depression in patients with chronic renal failure on different treatment modalities: A matched‐cohort and population‐based study in Taiwan
This study investigated 89,336 study controls, 17,889 patients with chronic kidney disease on conservative treatment, 3823 patients on hemodialysis (HD), 351 patients on peritoneal dialysis (PD), and 322 patients who had RT. We followed all individuals until the occurrence of major depression or the date of loss to follow‐up. The PD group had the highest risk (hazard ratio [HR] 2.43; 95% confidence interval [CI] 1.26–4.69), whereas the RT group had the lowest risk (HR 0.18; 95% CI 0.03–1.29) of developing major depression compared with the control group. Patients initiated on PD had a higher risk of developin...
Source: Hemodialysis International - July 1, 2015 Category: Hematology Authors: Shih‐Feng Chen, I‐Jen Wang, Hui‐Chu Lang Tags: Original Article Source Type: research

Efficacy of losartan for improving insulin resistance and vascular remodeling in hemodialysis patients
Abstract Insulin resistance and vascular remodeling are prevalent and predict cardiovascular mortality in hemodialysis patients. Angiotensin II (Ang II) may be involved in both pathogenesis. In the present study, we investigated the effects of the Ang II receptor blocker losartan on insulin resistance, arterial stiffness, and carotid artery structure in hemodialysis patients. Seventy‐two hemodialysis patients were randomly assigned to receive either losartan 50 mg qd (n = 36) or β‐blocker bisoprolol 5 mg qd (n = 36). At the start and at month 12, ambulatory blood pressure ...
Source: Hemodialysis International - June 24, 2015 Category: Hematology Authors: Fang Sun, Yan Song, Jing Liu, Li‐Jie Ma, Yang Shen, Jing Huang, Yi‐Lun Zhou Tags: Original Article Source Type: research

Role of T‐regulatory cells in the response to hepatitis B vaccine in hemodialysis patients
Abstract Human disease elicits a complex array of biological processes that results in long‐term protective immunological memory to infectious agents. Chronic kidney disease is known to impair induction of sustained immunological memory to hepatitis B vaccine (HBVax) antigens. We asked the question: Does end‐stage renal disease promote changes in subtypes of regulatory T (Treg) cells that correlate with diminished amnestic response to HBVax antigen compared to healthy controls? The study design and setting was a prospective observational cohort at a veterans affairs medical center. End‐stage renal disease patients on...
Source: Hemodialysis International - June 23, 2015 Category: Hematology Authors: Roy O. Mathew, Darius L. Mason, Renjie Song, Tiffany Tryniszewski, Jeffrey S. Kennedy Tags: Original Article Source Type: research

Handbook of Dialysis Fifth Edition by John T. Daugirdas, Peter G. Blake and Todd S. Ing. Philadelphia, PA: Lippincott Williams & Wilkins, 2014, 900 pp. (ISBN‐13: 978‐1451144291)
(Source: Hemodialysis International)
Source: Hemodialysis International - June 5, 2015 Category: Hematology Authors: Jochen G. Raimann Tags: Book Review Source Type: research

The source of net ultrafiltration during hemodialysis is mostly the extracellular space regardless of hydration status
Abstract Fluid shifts are common in patients undergoing chronic hemodialysis (HD) during the intradialytic periods, as several liters of fluid are removed during ultrafiltration (UF). Some patients have experienced frequent intradialytic hypotension (IDH). However, the characteristics of fluid shifts and which fluid space is affected remain controversial. Therefore, we designed this study to evaluate the fluid spaces most affected by UF and to determine whether hydration status influences the fluid shifts during HD. This was a prospective cohort study of 40 patients undergoing HD. We measured the patient's fluid spaces usi...
Source: Hemodialysis International - June 5, 2015 Category: Hematology Authors: Hyeonju Jeong, Chae‐Wan Lim, Hye‐Min Choi, Dong‐Jin Oh Tags: Original Article Source Type: research

Febuxostat improves endothelial function in hemodialysis patients with hyperuricemia: A randomized controlled study
This study is performed to assess the effect of febuxostat on endothelial dysfunction in hemodialysis patients with hyperuricemia. We randomly assigned 53 hemodialysis patients with hyperuricemia to a febuxostat (10 mg daily) group and a control group and measured flow‐mediated dilation, serum uric acid (UA) levels, systolic and diastolic blood pressure, malondialdehyde‐modified low‐density lipoprotein (MDA‐LDL), and highly sensitive C‐reactive protein (hsCRP) at baseline and at the end of a 4‐week study period. Flow‐mediated dilation increased from 5.3% ± 2.4% to 8.9% &plus...
Source: Hemodialysis International - May 21, 2015 Category: Hematology Authors: Yuki Tsuruta, Kan Kikuchi, Yukio Tsuruta, Yuko Sasaki, Takahito Moriyama, Mitsuyo Itabashi, Takashi Takei, Keiko Uchida, Takashi Akiba, Ken Tsuchiya, Kosaku Nitta Tags: Original Article Source Type: research

Depressive symptom severity, contributing factors, and self‐management among chronic dialysis patients
Abstract Despite the high prevalence of depressive symptoms in patients receiving chronic dialysis, there has been inadequate attention to patient‐related barriers to management of depressive symptoms, such as factors identified by these patients as contributing to their symptoms, and how they responded to the symptoms. Participants (N = 210) in an ongoing longitudinal observational study of multidimensional quality of life in patients receiving chronic dialysis completed a battery of measures monthly for 12 months. For each patient at each measurement point, an event report was generated if he or she score...
Source: Hemodialysis International - May 21, 2015 Category: Hematology Authors: Mi‐Kyung Song, Sandra E. Ward, Gerald A. Hladik, Jessica C. Bridgman, Constance A. Gilet Tags: Original Article Source Type: research

Burden and coping strategies among Jordanian caregivers of patients undergoing hemodialysis
This study aims to explore the burdens and coping strategies of caregivers of patients receiving hemodialysis. Caregivers of patients undergoing hemodialysis (n = 139) at 3 dialysis units were given 3 forms: Caregiver and Patient Characteristics, Oberst Caregiving Burden Scale Difficulty Subscale, and Ways of Coping Questionnaire. Descriptive statistics, correlational analysis, and multiple regression analysis were performed. The Oberst Caregiving Burden Scale was significantly related to self‐controlling (r = 0.20) and seeking social support (r = 0.17). Caregiver burden was posi...
Source: Hemodialysis International - May 21, 2015 Category: Hematology Authors: Eman Khamis Alnazly Tags: Original Article Source Type: research

The relationship between symptoms and blood pressure during maintenance hemodialysis
Abstract Intradialytic hypotension (IDH) is a detrimental complication of maintenance hemodialysis, but how it is defined and reported varies widely in the literature. European Best Practice Guideline and Kidney Disease Outcomes Quality Initiative guidelines require symptoms and a mitigating intervention to fulfill the diagnosis, but morbidity and mortality outcomes are largely based on blood pressure alone. Furthermore, little is known about the incidence of asymptomatic hypotension, which may be an important cause of hypoperfusion injury and impaired outcome. Seventy‐seven patients were studied over 456 dialysis sessio...
Source: Hemodialysis International - May 7, 2015 Category: Hematology Authors: David J. Meredith, Christopher W. Pugh, Sheera Sutherland, Lionel Tarassenko, Jacqueline Birks Tags: Original Article Source Type: research

The effect of hemodialysis session on postural strategies in older end‐stage renal disease patients
Abstract Patients suffering from end‐stage renal disease experience multiple disabilities, such as muscle wasting, weakness, higher postural sway, and fall rates compared with healthy population, which has a negative effect on physical functioning and autonomy. The vital treatment of hemodialysis is recognized to induce important post‐hemodialysis fatigue, hypotension, cramps, and headache due to the rapid fluid redistribution, among others. Nevertheless, even the well‐known negative effect of aforementioned consequences of hemodialysis treatment, its effect on physical function, especially postural balance, is uncle...
Source: Hemodialysis International - April 28, 2015 Category: Hematology Authors: Justine Magnard, Julien Lardy, Angelo Testa, Dan Hristea, Thibault Deschamps Tags: Original Article Source Type: research

Extracellular superoxide dismutase release by enoxaparin and sparing effect of heparin‐grafted hemodialyzer
(Source: Hemodialysis International)
Source: Hemodialysis International - April 28, 2015 Category: Hematology Authors: Jacek Borawski, Joanna Gozdzikiewicz‐Lapinska, Beata Naumnik Tags: Letter to the Editor Source Type: research

Catheter tip malposition after percutaneous placement of tunneled hemodialysis catheters
Abstract The percutaneous catheterization of central veins is increasingly used in nephrological practice as a temporary or permanent vascular access. The aim of our study was to present and to analyze episodes of catheter tip malposition during percutaneous tunneled hemodialysis catheter insertion in the large, unselected group of patients. All patients who underwent the procedure of catheter insertion in our department during year 2012 were analyzed retrospectively. One hundred four tunneled hemodialysis catheters were inserted in 101 patients. In 58 patients, the catheter was inserted at the initiation of hemodialysis t...
Source: Hemodialysis International - April 16, 2015 Category: Hematology Authors: Ewa Weber, Tomasz Liberek, Wojciech Wołyniec, Bolesław Rutkowski Tags: Original Article Source Type: research

Use of the subcutaneous venous network of the forearm to create an arteriovenous fistula
In conclusion, making use of veins of the subcutaneous venous network of the forearm for creation of a native fistula should be considered in selected cases. (Source: Hemodialysis International)
Source: Hemodialysis International - April 16, 2015 Category: Hematology Authors: Tomasz Gołębiowski, Krzysztof Letachowicz, Waldemar Letachowicz, Mariusz Kusztal, Jerzy Garcarek, Beata Strempska, Wacław Weyde, Marian Klinger Tags: Case Report Source Type: research

The influence of socioeconomic status on patient survival on chronic dialysis
Abstract Socioeconomic status (SES) has been linked to worse end‐stage kidney disease survival. The effect of SES on survival on chronic dialysis, including the impact of transplantation, was examined. A retrospective, observational study investigated the association of SES with dialysis patient survival, with censoring at time of transplantation. Adult patients commencing dialysis from 1990 to 2009 in an Irish tertiary center received a spatial SES score using the 2011 Pobal Haase‐Pratschke Deprivation Index and were compared by quartile. Cox proportional hazard models and Kaplan–Meier survival analysis examined...
Source: Hemodialysis International - April 9, 2015 Category: Hematology Authors: Frank L. Ward, Patrick O'Kelly, Fionnuala Donohue, Coilín O'Haiseadha, Trutz Haase, Jonathan Pratschke, Declan G. deFreitas, Howard Johnson, Conall M. O'Seaghdha, Peter J. Conlon Tags: Original Article Source Type: research

“Angiography without contrast”: Severe vascular calcification in chronic kidney disease
(Source: Hemodialysis International)
Source: Hemodialysis International - April 9, 2015 Category: Hematology Authors: Zeynep Erturk, Seyyid Bilal Acikgoz, Yalcin Solak Tags: Letter to the Editor Source Type: research

Prevalence of uremic itching in patients undergoing hemodialysis
This study was carried out to determine the factors affecting and incidence of itching in patients undergoing hemodialysis treatment. The descriptive study was carried out in 130 patients who underwent hemodialysis treatment because of end‐stage renal disease in Eastern Turkey between October 2014 and December 2014. A questionnaire prepared by the researcher based on the literature and the Visual Analog Scale were used for data collection. The data were collected by the researcher through face‐to‐face interviews in the hemodialysis unit. The evaluation of data obtained in the research has been performed using SPSS 16...
Source: Hemodialysis International - April 9, 2015 Category: Hematology Authors: Mehtap Kavurmacı Tags: Original Article Source Type: research

Effect of high‐protein supplemental therapy on subjective global assessment of CKD‐5D patients
Abstract Adequate nutrition in patients on hemodialysis is an important step for improving the quality of life. This prospective study was undertaken to monitor the nutritional status of patients who were given high‐protein supplements on malnutrition inflammation score (MIS) and to correlate with biochemical parameters in maintenance hemodialysis (MHD) patients. This prospective study was conducted on 55 chronic kidney disease patients on MHD (37 women, 18 men), aged between 21 and 67 years. Of the 55 patients, 26 patients received high‐protein commercial nutritional supplements, whereas 29 patients received high‐pr...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Anand Yuvaraj, Madhusudan Vijayan, Marina Alex, Georgi Abraham, Sanjeev Nair Tags: Original Article Source Type: research

Time trends in the association of ESRD incidence with area‐level poverty in the US population
The objective of this study was to examine the temporal trends of the association between area‐level poverty status and end‐stage renal disease (ESRD) incidence. We hypothesized that the association between area‐level poverty status and ESRD incidence has increased significantly over time. Patient data from the United States Renal Data System were linked with data from the 2000 and 2010 US census. Area‐level poverty was defined as living in a zip code‐defined area with ≥20% of households living below the federal poverty line. Negative binomial regression models were created to examine the association between a...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Bridget H. Garrity, Holly Kramer, Kavitha Vellanki, David Leehey, Julia Brown, David A. Shoham Tags: Original Article Source Type: research

Acute kidney injury after near drowning: The way from the beach to hemodialysis
Abstract Acute kidney injury (AKI) occurs in many different situations and may have a variable prognosis influenced by clinical setting, underlying cause, and comorbidity. This is important because of the high mortality and morbidity risk affecting many people around the world. Near‐drowning related AKI requiring hemodialysis is very seldom reported in literature. Although cardiovascular and respiratory disorders are more frequently seen after this entity, we aimed to emphasize this rare but dangerous complication in near‐drowning patients. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Alper Alp, Hakan Akdam, İbrahim Meteoğlu, Alparslan Ünsal, Harun Akar, Yavuz Yeniçerioğlu Tags: Case Report Source Type: research

Disseminated tuberculosis mimicking metastatic colon cancer in a hemodialysis patient
(Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Juliana Bento‐da‐Cunha, Sergio R. Cavechia, Alfredo N.C. Santana Tags: Letter to the Editor Source Type: research

Life‐threatening spontaneous kidney rupture in a rare case with systemic lupus erythematosus: Prompt diagnosis with computed tomography
We present the case of a 30‐year‐old female with spontaneous parenchymal rupture of the right kidney who had renal failure due to SLE and presented with atraumatic sudden right flank pain during hemodialysis treatment. To our knowledge, this case is the second report of SLE manifesting as spontaneous kidney rupture in the literature. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Furkan Ufuk, Duygu Herek Tags: Case Report Source Type: research

Bilateral quadriceps and triceps tendon rupture in a hemodialysis patient
Abstract This paper presented a 58‐year‐old hemodialysis patient who had bilateral quadriceps and triceps tendon rupture, whereby the role of rehabilitation in functional parameters has been highlighted. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Özlem Taşoğlu, Timur Ekiz, Didem Yenigün, Müfit Akyüz, Neşe Özgirgin Tags: Case Report Source Type: research

Association of low vitamin D levels with metabolic syndrome in hemodialysis patients
Abstract Low vitamin D levels have been linked to metabolic syndrome in the general population. In the present study, the relationship between inadequate serum concentrations of vitamin D and metabolic syndrome in patients with end‐stage renal disease undergoing hemodialysis was explored. In a cross‐sectional setting, 145 patients undergoing maintenance hemodialysis were enrolled. Metabolic syndrome was defined using the International Diabetes Federation criteria. Serum concentration of 25(OH) vitamin D was determined by a commercially available enzyme immunosorbent assay method. The prevalence of metabolic syndrome wa...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Farrokhlagha Ahmadi, Samaneh Damghani, Mahboob Lessan‐Pezeshki, Effat Razeghi, Sima Maziar, Mitra Mahdavi‐Mazdeh Tags: Original Article Source Type: research

Phosphate binder pill burden, patient‐reported non‐adherence, and mineral bone disorder markers: Findings from the DOPPS
Abstract Because of multiple comorbidities, hemodialysis (HD) patients are prescribed many oral medications, including phosphate binders (PBs), often resulting in a high “pill burden.” Using data from the international Dialysis Outcomes and Practice Patterns Study (DOPPS), we assessed associations between PB pill burden, patient‐reported PB non‐adherence, and levels of serum phosphorus (SPhos) and parathyroid hormone (PTH) using standard regression analyses. The study included data collected from 5262 HD patients from dialysis units participating in the DOPPS in 12 countries. PB prescription ranged from a m...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Rachel B. Fissell, Angelo Karaboyas, Brian A. Bieber, Ananda Sen, Yun Li, Antonio A. Lopes, Takashi Akiba, Jürgen Bommer, Jean Ethier, Michel Jadoul, Ronald L. Pisoni, Bruce M. Robinson, Francesca Tentori Tags: Original Article Source Type: research

The Glycemic Indices in Dialysis Evaluation (GIDE) study: Comparative measures of glycemic control in diabetic dialysis patients
Abstract The validity of hemoglobin A1c (HgbA1c) is undergoing increasing scrutiny in the advanced CKD/ESRD (chronic kidney disease/end‐stage renal disease) population, where it appears to be discordant from other glycemic indices. In the Glycemic Indices in Dialysis Evaluation (GIDE) Study, we sought to assess correlation of HgbA1c with casual glucose, glycated albumin, and serum fructosamine in a large group of diabetic patients on dialysis. From 26 dialysis facilities in the United States, 1758 diabetic patients (hemodialysis = 1476, peritoneal dialysis = 282) were enrolled in the first qua...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Mark E. Williams, Neal Mittman, Lin Ma, Julia I. Brennan, Ann Mooney, Curtis D. Johnson, Chinu M. Jani, Franklin W. Maddux, Eduardo Lacson Tags: Original Article Source Type: research

Brachial‐cephalic fistula recovered with drainage for the basilic vein: Case report
We present and discuss the case of a woman aged 69 years in HD in which a brachial‐cephalic fistula with drainage to basilic vein was created, through rotation of the cephalic vein on the forearm level. This kind of access serves to prolong the time spent dialyzing through native fistulae, with their reduced complications and greater cost‐effectiveness. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Clemente Neves Sousa, António Norton de Matos, Ana Rocha, Paulo Almeida, Eva Xavier Tags: Case Report Source Type: research

Parathyroidectomized patients have impaired capacity of peripheral vascular constriction during hemodialysis
In conclusion, parathyroidectomized patients have impaired capacity of vasoconstriction in response to ultrafiltration, an effect independent of serum PTH levels. Further studies are needed to elucidate mechanisms explaining the interaction between PTx and systemic vascular tonus. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Bruno C. Silva, Rosa M. A. Moysés, Vitor B. Silva, Geraldo R. R. Freitas, Rosilene M. Elias Tags: Original Article Source Type: research

Association of bioimpedance spectroscopy‐based volume estimation with postdialysis hypotension in patients receiving hemodialysis
Abstract Clinical examination to determine the dry weight of patients on hemodialysis (HD) has been problematic, with studies showing discordance between physician assessment and objective measures of volume status.We studied the association between predialysis bioimpedance spectroscopy (BIS)‐based estimates of fluid overload and postdialysis hypotension in 635 patients in the United States Renal Data System ACTIVE/ADIPOSE (A Cohort study To Investigate the Value of Exercise/Analyses Designed to Investigate the Paradox of Obesity and Survival in ESRD) study receiving HD in 2009–2011. We recorded predialysis and pos...
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Adrian P. Abreo, Glenn M. Chertow, Lorien S. Dalrymple, George A. Kaysen, Kirsten L. Johansen Tags: Original Article Source Type: research

Single‐lumen tunneled catheter: An old but useful option
We report a case of long‐term uneventful catheter use in a patient with previous recurrent vascular access dysfunction and infection. A single‐lumen tunneled catheter was inserted into the left internal jugular vein after a failed attempt of dual‐lumen permanent catheter placement. The follow‐up since device implantation has exceeded 5 years without any complications related to vascular access. (Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Krzysztof Letachowicz, Tomasz Gołębiowski, Mariusz Kusztal, Waldemar Letachowicz, Wacław Weyde, Marian Klinger Tags: Case Report Source Type: research

Preface
(Source: Hemodialysis International)
Source: Hemodialysis International - April 1, 2015 Category: Hematology Authors: Christopher R. Blagg Tags: Preface Source Type: research

Clinical features, therapy, and outcome of calciphylaxis in patients with end‐stage renal disease on renal replacement therapy: Case series
(Source: Hemodialysis International)
Source: Hemodialysis International - March 26, 2015 Category: Hematology Authors: Kian‐Guan Lee, Amy Ee‐Lin Lim, Jiunn Wong, Lina Hui‐Lin Choong Tags: Letter to the Editor Source Type: research

Remove or not, that is the question: A case report on carotid artery cannulation during indwelling venous hemodialysis catheter
Abstract A 58‐year‐old woman visited the emergency department for acute occlusion of arteriovenous fistula. One session of hemodialysis was scheduled via temporary venous hemodialysis catheter before thrombectomy. Unfortunately, neck arterial cannulation was discovered after complete placement of catheter. The catheter was removed immediately but bleeding could not be stopped. Pseudoaneurysm over the right carotid artery was proved by angiography and repaired by graft stent. Arterial cannulation during venous hemodialysis catheter insertion is a rare but serious complication and there is no standard response recommende...
Source: Hemodialysis International - March 26, 2015 Category: Hematology Authors: Cheng‐Chieh Yen, Yi‐Wen Chiu, Hung‐Chun Chen Tags: Case Report Source Type: research

Personal viewpoint: Limiting maximum ultrafiltration rate as a potential new measure of dialysis adequacy
Abstract While the solute clearance marker (Kt/Vurea) is widely used, no effective marker for volume management exists. Two principles apply to acute volume change in hemodialysis: (1) the plasma refill rate, the maximum rate the extracellular fluid can replace a contracting intravascular volume (±5 mL/kg/hour) and (2) the rate of intravascular volume contraction where coronary hypoperfusion, myocardial stun, and vascular risk escalates (observed at ≥10 mL/kg/hour). In extended hour and higher frequency hemodialysis, intravascular contraction rates are usually equilibrated by the plasma refill rate,...
Source: Hemodialysis International - March 16, 2015 Category: Hematology Authors: John W M Agar Tags: Special Article Source Type: research

Prevalence and correlates of functional dependence among maintenance dialysis patients
Abstract Functional dependence is an important determinant of longevity and quality of life. The purpose of the current study was to determine the prevalence and correlates of functional dependence among patients with end‐stage renal disease (ESRD) receiving maintenance dialysis. We enrolled 148 participants with ESRD from five clinics. Functional status, as measured by basic and instrumental activities of daily living (ADL, IADL), was ascertained by validated questionnaires. Functional dependence was defined as needing assistance in at least one of seven IADLs or at least one of four ADLs. Demographic characteristics, c...
Source: Hemodialysis International - March 2, 2015 Category: Hematology Authors: Niall T. Kavanagh, Brigitte Schiller, Anjali B. Saxena, I‐Chun Thomas, Manjula Kurella Tamura Tags: Original Article Source Type: research

Occult hepatitis B among patients with chronic renal failure on hemodialysis from a capital city in northeast Brazil
Abstract Occult hepatitis B (OHB) is characterized by the presence of HBV‐DNA in the absence of HBsAg in the serum of patients. Hemodialysis patients are at high risk for hepatitis B virus and there are few data on the prevalence of OHB in this population, mainly in Brazil. Thus, the aim of this study was to determine the prevalence of OHB in patients undergoing hemodialysis. A cross‐sectional study was performed, including 301 patients on chronic hemodialysis at two dialysis centers in São Luís (Maranhão), northeast Brazil. Serological tests were performed for HBsAg, anti‐HBc, anti‐HBs, and an...
Source: Hemodialysis International - March 2, 2015 Category: Hematology Authors: Andrea Martins Melo Fontenele, Juliana Braga Furtado Gainer, Daniel Viana Silva e Silva, Max Diego Cruz Santos, João Victor Salgado, Natalino Salgado Filho, Adalgisa Sousa Paiva Ferreira Tags: Scholarly Review (Solicited) Source Type: research

Morphometric and histological parameters in veins of diabetic patients undergoing brachiocephalic fistula placement
Abstract Diabetic patients with end‐stage renal failure have higher rates of arteriovenous failures when compared with nondiabetics. The aim was to compare differences in indicators of vascular remodeling and endothelial dysfunction in veins of patients with or without diabetes at the time of surgical placement. In this prospective observational trial, vein samples were collected from patients when a brachiocephalic fistula was created. Morphometric measurements and extent of fibrosis were determined using Image J software. Histological analysis, for the presence of myofibroblasts and level of endothelial nitric oxide sy...
Source: Hemodialysis International - March 2, 2015 Category: Hematology Authors: Ivana Lazich, Anthony Chang, Sydeaka Watson, Promila Dhar, Rama S. Madhurapantula, Mary Hammes Tags: Original Article Source Type: research

End‐stage renal disease from hemolytic uremic syndrome in the United States, 1995–2010
Abstract Management of hemolytic uremic syndrome (HUS) has evolved rapidly, and optimal treatment strategies are controversial. However, it is unknown whether the burden of end‐stage renal disease (ESRD) from HUS has changed, and outcomes on dialysis in the United States are not well described. We retrospectively examined data for patients initiating maintenance renal replacement therapy (RRT) (n = 1,557,117), 1995–2010, to define standardized incidence ratios (SIRs) and outcomes of ESRD from HUS) (n = 2241). Overall ESRD rates from HUS in 2001–2002 were 0.5 cases/million per year ...
Source: Hemodialysis International - February 17, 2015 Category: Hematology Authors: Donal J. Sexton, Scott Reule, Craig A. Solid, Shu‐Cheng Chen, Allan J. Collins, Robert N. Foley Tags: Original Article Source Type: research

Renal involvement in mushroom poisoning: The case of Orellanus syndrome
Abstract Although mushroom poisoning is a rare cause of acute renal injury, in some cases it may lead to the development of a severe and irreversible renal failure. Orellanus syndrome is the most important example of organic renal damage related to mushroom consumption. It is caused by the ingestion of orellanine, the main toxin of different types of Cortinarius mushrooms (Cortinarius speciosissimus, C. orellanus, C. orellanoides, etc.), and it is characterized by progressive clinical phases with a predominant kidney involvement, finally requiring renal replacement therapy in about 10% of cases. Renal damage ...
Source: Hemodialysis International - February 4, 2015 Category: Hematology Authors: Pasquale Esposito, Edoardo La Porta, Marta Calatroni, Stefania Bianzina, Carmelo Libetta, Marilena Gregorini, Teresa Rampino, Antonio Dal Canton Tags: Case Report Source Type: research

Hemodialysis decreases carotid‐brachial and carotid‐femoral pulse wave velocities: A 5‐year follow‐up study
Abstract Aortic stiffness is a prognostic parameter associated with patient mortality. Vascular access creation has been shown to have effects on arterial stiffness both in the aorta and in the upper limb arteries in chronically hemodialyzed patients (CHPs). However, no longitudinal studies have been conducted in order to characterize the evolution of arterial stiffness in CHPs. The aims of this work were (a) to measure baseline pulse wave velocity (PWV) in the carotid‐femoral and in right and left carotid‐brachial pathways in a cohort of CHP and (b) to conduct a 5‐year prospective study on the same cohort to determi...
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Edmundo I. Cabrera Fischer, Daniel Bia, Cintia Galli, Rodolfo Valtuille, Yanina Zócalo, Sandra Wray, Ricardo L. Armentano Tags: Original Article Source Type: research

Successful medical treatment of emphysematous pyelonephritis in chronic hemodialysis
We report the case of a 77‐year‐old woman with diabetes and end‐stage renal disease on chronic hemodialysis that presented with fever and left flank pain. A bubbly gas pattern inside the left kidney was demonstrated on abdominal computed tomography scan and blood cultures grew Escherichia coli. She was successfully treated solely with systemic antibiotics. This highlights the fact that prompt recognition of imaging findings associated with benign prognosis is essential for a favorable outcome. It allows for an effective management avoiding high‐risk interventions, especially in frail patients with multiple comorbid...
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Georgios Vlachopanos, Theodoros Kassimatis, Adamantia Zerva, Anastasia Kokkona, Eirini Stavroulaki, Charilaos Zacharogiannis, Athanasios Agrafiotis Tags: Case Report Source Type: research

Serum sulfatide abnormality is associated with increased oxidative stress in hemodialysis patients
This study demonstrated, for the first time, a time‐dependent aggravation of serum sulfatide abnormality in hemodialysis patients, as well as the potential relationship between serum sulfatide abnormality and increasing oxidative stress. These findings suggest that oxidative stress might be an aggravating factor in serum sulfatide abnormality. As continuation of hemodialysis treatment hardly improves abnormal serum sulfatide levels or increased oxidative stress, development of novel therapeutic strategies may be important. (Source: Hemodialysis International)
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Huang Yuzhe, Yuji Kamijo, Koji Hashimoto, Makoto Harada, Taro Kanno, Eiko Sugiyama, Mamoru Kyogashima, Tomomasa Oguchi, Takero Nakajima, Yutaka Kanno, Toshifumi Aoyama Tags: Original Article Source Type: research

Catheter‐related bacteremia and mortality in frequent nocturnal home hemodialysis
Abstract Frequent nightly home hemodialysis (NHHD) has emerged as an attractive alternative to thrice weekly in‐center hemodialysis, albeit with preponderant long‐term hemodialysis catheter used. Sixty‐three NHHD patients from University of Virginia Lynchburg Dialysis Facility were matched 1:2 with 121 conventional hemodialysis patients admitted to Fresenius Medical Care North America facilities from January 1, 2007 to December 31, 2010. Matching considered age (± 5 years), gender, race, dialysis vintage, and diabetes. The primary end‐point was the combined incidence of bacteremia/sepsis, for up to 20...
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Hui Xue, Nien‐Chen Li, Eduardo Lacson, Steven M. Brunelli, Robert S. Lockridge Tags: Original Article Source Type: research

Echocardiographic epicardial adipose tissue measurements provide information about cardiovascular risk in hemodialysis patients
Abstract Epicardial adipose tissue (EAT) is a cardiovascular risk predictor in general population. However, its value has not been well validated in maintainance hemodialysis (MHD) patients. We aimed to assess associations of EAT with cardiovascular risk predictors in nondiabetic MHD patients. In this cross‐sectional study, we measured EAT thickness by transthoracic echocardiography in 50 MHD patients (45.8 ± 14.6 years of age, 37 male). Antropometric measurements, bioimpedance analysis, left ventricular (LV) mass, carotis intima media thickness, blood tests, homeostasis model assessment for insulin ...
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Gülay Ulusal Okyay, Kaan Okyay, Evşen Polattaş Solak, Asife Sahinarslan, Özge Paşaoğlu, Fatma Ayerden Ebinç, Hatice Paşaoğlu, Ülver Boztepe Derici, Şükrü Sindel, Turgay Arınsoy Tags: Original Article Source Type: research

Clinical and psychosocial factors predicting health‐related quality of life in hemodialysis patients
Abstract Many patients with end‐stage renal disease have significant impairment in health‐related quality of life (HRQoL). Most previous studies have focused on clinical factors; however, quality of life can also be affected by psychosocial factors. The aim of this study was to identify the possible predictors of HRQoL among clinical and psychosocial factors in hemodialysis (HD) patients. The study included 101 patients who were undergoing HD. Psychosocial factors were evaluated using the Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support, Montreal Cognitive Assessment, and Pittsb...
Source: Hemodialysis International - February 3, 2015 Category: Hematology Authors: Gun Woo Kang, In Hee Lee, Ki Sung Ahn, Jonghun Lee, Yunmi Ji, Jungmin Woo Tags: Original Article Source Type: research

2014 List of Reviewers
(Source: Hemodialysis International)
Source: Hemodialysis International - January 14, 2015 Category: Hematology Tags: 2014 List of Reviewers Source Type: research