Impact of frailty on disease-specific health status in cardiovascular disease
Frailty is a syndrome of older age that reflects an impaired physiological reserve and decreased ability to recover from medical stressors. While the impact of frailty on mortality in cardiovascular disease has been well described, its impact on cardiovascular disease–specific health status—cardiac symptoms, physical functioning and quality of life—has been less well studied. In this review, we summarise the impact of frailty on health status outcomes across different cardiovascular conditions. In heart failure, frail patients have markedly impaired disease-specific health status and are at risk for subse...
Source: Heart - June 14, 2023 Category: Cardiology Authors: Nguyen, D. D., Arnold, S. V. Tags: Review articles Reviews Source Type: research
Cardiovascular phenotypes and incident cardiovascular events in people with previous cancer
As the intersection between cardiology and oncology continues to expand, much has been said about the shared risk factors of these conditions, in particular, tobacco use, a suboptimal diet and physical inactivity.1 In addition, the reported cardiovascular toxicity of cancer therapy in all its forms has been extensively documented and appropriately has raised our collective awareness. The importance of heart disease in patients undergoing cancer care cannot be understated, but also how critical it becomes to prioritise a care continuum after cancer is survived. The fantastic progress in the treatment and even cure of malign...
Source: Heart - June 14, 2023 Category: Cardiology Authors: Banchs, J., Lech, T. Tags: Press releases Editorials Source Type: research
Exercise and arrhythmogenic cardiomyopathy: all things in moderation
Since right ventricular (RV) dysplasia was described in an autopsy case series of young adults with sudden cardiac death (SCD) in the early 1980s,1 researchers have sought to unravel the complex relationship between exercise and SCD in arrhythmogenic right ventricular cardiomyopathy (ARVC). Advanced cardiac imaging and genetic testing have since enriched our understanding of how pathogenic variants in an expanding array of genes manifest cardiomyopathy of either ventricle and a propensity toward ventricular arrythmia. The more inclusive term arrhythmogenic cardiomyopathy (ACM) was created to recognise the potential for lef...
Source: Heart - June 14, 2023 Category: Cardiology Authors: Bevan, G., Nazer, B. Tags: Editorials Source Type: research
Exercising good judgement: what is the evidence for exercise training in tetralogy of Fallot?
It is widely recognised that regular exercise can have a salutary effect on cardiovascular health. Additionally, consistent physical activity can be beneficial for mental health, can ameliorate a variety of chronic diseases and can translate into improved self-esteem.1 However, individuals with congenital heart disease (CHD) may be reluctant to accept an exercise prescription if thought to have uncertain clinical benefit or if perceived to be potentially unsafe for their hearts. Practitioners themselves may be unclear as to how to prescribe or interpret adequacy of exercise results in their CHD patients. As a whole,...
Source: Heart - June 14, 2023 Category: Cardiology Authors: Wald, R., Leonardi, B., Dallaire, F. Tags: Editorials Source Type: research
Heartbeat: cancer history and risk of cardiovascular disease
The number of patients with a history of cancer is increasing due to improved cancer diagnosis and treatment over the past few decades. Although the issue of immediate cancer therapy related cardiotoxicity is well recognised, less attention has been directed towards the long-term risk of cardiovascular disease (CVD) in patients with prior cancer. In this issue of Heart, Raisi-Estabragh and colleagues1 used a propensity matched design with competing risk regression to study the associations between cancer and CVD in 18 714 UK Biobank participants with a cancer history. Participants with cancer had a high burden of prevalent...
Source: Heart - June 14, 2023 Category: Cardiology Authors: Otto, C. M. Tags: Highlights from this issue Source Type: research
