Structured Weaning From the Impella Left Ventricular Micro-Axial Pump in Acute Myocardial Infarction With Cardiogenic Shock and Protected Percutaneous Coronary Intervention: Experience From a Non-Cardiac Surgical Centre
The Impella (Abiomed, Danvers, MA, USA) temporary percutaneous left ventricular assist device is increasingly used as mechanical circulatory support in patients with acute myocardial infarction –cardiogenic shock (AMICS) or those undergoing high-risk protected percutaneous coronary intervention (PCI). The optimal weaning regimen remains to be defined. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 21, 2024 Category: Cardiology Authors: Ryan J. Slack, Forbes McGain, Nicholas Cox, Craig French, Victoria Cheng, Dion Stub, Brian Zakhem, Fabien Dade, Jason E. Bloom, William Chan, Yang Yang Tags: Original Article Source Type: research

Modifiable and Non-Modifiable Risk Factors for Premature Coronary Heart Disease (PCHD): Systematic Review and Meta-Analysis
We aimed to compare the prevalence of modifiable and non-modifiable coronary heart disease (CHD) risk factors among those with premature CHD and healthy individuals. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 19, 2024 Category: Cardiology Authors: Adeel Khoja, Prabha H. Andraweera, Zohra S. Lassi, Zahra A. Padhani, Anna Ali, Mingyue Zheng, Maleesa M. Pathirana, Emily Aldridge, Melanie R. Wittwer, Debajyoti D. Chaudhuri, Rosanna Tavella, Margaret A. Arstall Tags: Original Article Source Type: research

Recovery Rates of Diagnostic Cardiac Procedural Volume in Oceania 1 Year Into COVID-19: The IAEA Non-Invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID 2)
The aim of this study was to assess the recovery rates of diagnostic cardiac procedure volumes in the Oceania Region, midway through the coronavirus disease 2019 (COVID-19) pandemic. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: Anver Sethwala, Cole B. Hirschfeld, Patricia O'Sullivan, Mohamed Akbarally, John Younger, Niels Van Pelt, Michael Randazzo, Dora Lenturut-Katal, Joao V. Vitola, Rodrigo Cerci, Michelle C. Williams, Leslee J. Shaw, Ganesan Karthikeyan, Todd C. Villines, Sh Tags: Original Article Source Type: research

Efficacy of Guideline-Directed Medical Therapy in Heart Failure Patients With and Without Chronic Kidney Disease: A Meta-Analysis of 63,677 Patients
Chronic kidney disease (CKD) coexists in up to 50% of heart failure (HF) patients, affecting both those with reduced ejection fraction (HFrEF) and those with preserved ejection fraction (HFpEF). Although the efficacy of several guideline-directed medical therapies (GDMT) has been well established, the treatment recommendations are similar for those patients with HF with and without CKD. We aimed to investigate the efficacy of GDMT in patients with HF with versus those without CKD. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: Kameron M. Clark, Faraz Mahboob, Jack Evans, Jessica H. Sun, Nelson Wang Tags: Review Source Type: research

Low Mean Perfusion Pressure Indexed to Body Surface Area is a Powerful Predictor of Poor Outcomes After Heart Transplantation in Patients With High Pre-Transplant Venous Pressure: A Clinical Study With Physiological Insights From Mathematical Modelling of Biventricular Heart Failure
The deleterious consequences of chronically elevated venous pressure in patients with profound right ventricular or biventricular dysfunction are well known, including renal and hepatic dysfunction, and volume overload. The only option for these patients, if they fail optimal medical treatment, is a heart transplant, as they are not candidates for left ventricular assist device therapy. Mean perfusion pressure (MPP) is important in the outcomes of critically ill patients with high venous pressure. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: G. Rajagopalan, Komarakshi R. Balakrishnan, K.G. Suresh Rao, R. Ravi Kumar, Ramarathnam Krishna Kumar Tags: Original Article Source Type: research

Predicting Adverse Outcomes Following Catheter Ablation Treatment for Atrial Flutter/Fibrillation
To develop prognostic survival models for predicting adverse outcomes after catheter ablation treatment for non-valvular atrial fibrillation (AF) and/or atrial flutter (AFL). (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: Juan C. Quiroz, David Brieger, Louisa R. Jorm, Raymond W. Sy, Benjumin Hsu, Blanca Gallego Tags: Original Article Source Type: research

Implementation of Patient Blood Management in Orthotopic Heart Transplants: A Single Centre Retrospective Observational Review
Blood transfusion in the perioperative cardiothoracic setting has accepted risks including deep sternal wound infection, increased intensive care unit length of stay, lung injury, and cost. It has an immunomodulatory effect which may cause allo-immunisation. This may influence long-term survival through immune-mediated factors. Targeting coagulation defects to reduce unnecessary or inappropriate transfusions may reduce these complications. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: Jacob J. Rapier, Michael Daley, Susan E. Smith, Sean L. Goh, Swaroop Margale, Ian Smith, Bruce M. Thomson, Peter J. Tesar, Bronwyn L. Pearse Tags: Original Article Source Type: research

Cancer Therapies and Cardiomyocyte Viability: Which Drugs are Directly Cardiotoxic?
Increased cancer survivorship represents a remarkable achievement for modern medicine. Unfortunately, cancer treatments have inadvertently contributed to cardiovascular (CV) damage, significantly threatening the health and quality of life of patients living with, through and beyond cancer. Without understanding the mechanisms, including whether the cardiotoxicity is due to the direct or indirect effects on cardiomyocytes, prevention and management of cardiotoxicity can pose challenges in many patients. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: Lohis Balachandran, Tatt Jhong Haw, Angeline Jia Wen Leong, Amanda J. Croft, Dongqing Chen, Conagh Kelly, Aaron L. Sverdlov, Doan T.M. Ngo Tags: Research Letter Source Type: research

Robotic Assisted Percutaneous Coronary Intervention: Initial Australian Experience
Robotic-assisted percutaneous coronary intervention (R-PCI) has been increasingly performed overseas. Initial observations have demonstrated its clinical efficacy and safety with additional potential benefits of more accurate lesion assessment and stent deployment, with reduced radiation exposure to operators and patients. However, data from randomised controlled trials or clinical experience from Australia are lacking. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 15, 2024 Category: Cardiology Authors: James Leung, John French, James Xu, Hashim Kachwalla, Krishna Kaddapu, Tamer Badie, Christian Mussap, Rohan Rajaratnam, Dominic Leung, Sidney Lo, Craig Juergens Tags: Original Article Source Type: research

List of Reviewers 2023
The Editors wish to thank the following who reviewed manuscripts for Heart, Lung and Circulation during 2023: (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 14, 2024 Category: Cardiology Tags: List of Reviewers Source Type: research

High Incidence of Cardiovascular Disease in Patients With Oesophageal Cancer —A Registry-Based Cohort Study
The cardiovascular disease (CVD) burden among patients with oesophageal cancer (EC) treated with curative intent is unclear. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 9, 2024 Category: Cardiology Authors: Mette Marie A. S øndergaard, Marianne Nordsmark, Kirsten M. Nielsen, Jan B. Valentin, Søren P. Johnsen, Steen H. Poulsen Tags: Original Article Source Type: research

Integrating CardioOncology Across the Research Pipeline, Policy, and Practice in Australia —An Australian Cardiovascular Alliance Perspective
Over 18 million people worldwide were diagnosed with cancer in 2020, including over 150,000 people in Australia. Although improved early detection and treatment have increased the survival rates, cardiotoxic treatment and inadequate management of cardiovascular risk factors have resulted in cardiovascular disease (CVD) being one of the leading causes of non-cancer-related death and disability among cancer survivors. International guidelines outline the standards of care for CVD risk surveillance and management. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 9, 2024 Category: Cardiology Authors: Anna C. Singleton, Julie Redfern, Abbey Diaz, Bogda Koczwara, Stephen J. Nicholls, Kazuaki Negishi, Andre La Gerche, David Playford, Rachel Conyers, Daniel A. Cehic, Gail Garvey, Trent D. Williams, Lee Hunt, Kerry Doyle, Gemma A. Figtree, Doan T.M. Ngo, A Tags: DISCUSSION PAPER Source Type: research

Ebstein ’s Anomaly of the Tricuspid Valve, Mitral Valve Prolapse and Left Ventricular Non-Compaction: A Triple Trouble
We report here an extremely rare combination of LVNC, Ebstein’s anomaly of the TV and mitral valve prolapse in an adult. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 9, 2024 Category: Cardiology Authors: Swasthi S. Kumar, Sudipta Mondal, Saurav Banerjee Tags: Image Source Type: research

National Standards of Care for Childhood-onset Heart Disease (CoHD) —A New Paradigm Whereby Healthcare Professionals, Governments and Consumers Work Together to Optimise Patient Care
Congenital heart disease (CHD) is the commonest birth defect worldwide. Every year, 1.35 million children are born with CHD internationally, and approximately 2,400 in Australia. CHD kills twice as many children each year than all forms of childhood cancers combined, and 1 in every 10 children diagnosed with CHD does not live to adulthood [1]. In 2019, the Federal Government responded to the significant unmet needs in the fields of CHD by commissioning HeartKids Australia, the peak National CHD consumer body, to prepare a “National CHD Action Plan”. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - February 8, 2024 Category: Cardiology Authors: David S. Celermajer Tags: Editorial Source Type: research

Australian National Standards of Care for Childhood-onset Heart Disease (CoHD Standards). 1st Edition
These first Australian National Standards of Care for Childhood-onset Heart Disease (CoHD Standards) have been developed to inform the healthcare requirements for CoHD services and enable all Australian patients, families and carers impacted by CoHD (paediatric CoHD and adult congenital heart disease [ACHD]) to live their best and healthiest lives.The CoHD Standards are designed to provide the clarity and certainty required for healthcare services to deliver excellent, comprehensive, inclusive, and equitable CoHD care across Australia for patients, families and carers, and offer an iterative roadmap to the future of these ...
Source: Heart, Lung and Circulation - February 8, 2024 Category: Cardiology Authors: Gary F. Sholler, Lisa A. Selbie, Mary Tallon, Jessica Keating, Julian Ayer, Luke Burchill, Michael M.H. Cheung, Rachael Cordina, Evelyn Culnane, Shakira Donovan, Lucas Eastaugh, Caitlin Elliott, Jeffery Fletcher, Robert N. Justo, Nadine A. Kasparian, Andr Tags: Standards Source Type: research