The Effect of 12-Week Supervised Exercise-Based Cardiac Rehabilitation on Resting and Exercise Blood Pressure
This study aimed to investigate the effect of a 12-week exercise-based cardiac rehabilitation (CR) program on resting and exercise blood pressure (BP). (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: K. Janssens, V. Cornelissen, S. Foulkes, G. Claessen, A. Mitchell, A. La Gerche, K. Goetschalckx Source Type: research
A Cross Sectional Study of Capillary Blood Ketone Concentrations in Heart Failure Based on SGLT2i Use, Presence of Decompensation, and Heart Failure Type
This study determined the normal range of capillary ketones in patients with HF. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: J. Tan, J. Inglis, L. Ephraums, N. Simpson, M. Umapathysivam, H. Nguyen, J. Harris, C. Burdeniuk, C. De Pasquale, T. Thynne Tags: Cardiomyopathy / Heart Failure (055 –158) Source Type: research
A Novel Anti-Inflammatory and Anti-Fibrotic Agent, EBP979, Treatment Ameliorates Angiotensin II-Induced Ventricular Remodelling and Vascular Dysfunction
This study aimed to investigate the therapeutic potential of a novel anti-inflammatory and anti-fibrotic compound, EBP979, in young and old, female and male mice with angiotensin II (AngII) infusion. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: B. Wang, H. Liu, R. Magaye, S. Bailey, H. Kiriazis, D. Donner, B. Kemp-Harper, D. Kaye Source Type: research
A Pharmacist and Nurse-Led Warfarin Point-of-Care Management Program is Associated with Greater Time in Therapeutic Range in Patients With Ventricular Assist Devices
Ventricular assist devices (VAD) are lifesaving therapies that provide a temporary solution for patients awaiting heart transplantation. A VAD improves quality of life and reduces waitlist mortality. Antithrombotic therapy, usually with warfarin and aspirin, is required to reduce the risk of thromboembolic complications. In March 2020, a novel pharmacist and nurse-led warfarin point-of-care (POC) management program (PNLP) for VAD patients was established to reduce the requirement for patients to attend pathology clinics during the COVID pandemic, and provide optimal time in therapeutic range (TTR). (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: S. Toh, V. Warner, S. Poole Source Type: research
A Pilot Program Utilising a “Chatbot “ to Support Patients in the First 30 Days Following an Admission to Hospital With Acute Decompensated Heart Failure
Heart failure (HF) admissions are associated with mortality and are the key driver of HF-related costs. Patients typically deteriorate 2 weeks prior to readmission. The majority have no healthcare contact during this period. Patients and carers rarely recognise deterioration or potential triggers for deterioration; this, coupled with declining access to timely primary/specialist care, is a recipe for disaster. Could a “chatbot” intervention improve outcomes? (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: G. Vaddadi, F. Miller, N. Sharma, P. Venkataraman, M. Oo, N. Sutherland, J. Taylor, W. Van Gaal Source Type: research
A Rare Case of Peripartum Cardiomyopathy Complicated by Renal and Splenic Infarcts
Peripartum cardiomyopathy (PPCM) is a major cause of maternal morbidity and mortality. Complications include heart failure, thromboembolic disease, and left ventricular (LV) thrombus. Common thromboembolic events include pulmonary and cerebral embolism, limb ischaemia, and myocardial infarction. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: J. Yao, J. Wong, A. Aggarwal Source Type: research
A Regional Hospital Experience of Heart Failure Optimisation and Representations
This study aimed to look at the optimisation of HF patients, in those who were readmitted within 30 days of discharge. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: N. Goonetilleke, T. Sirisena, M. Baird, A. Ralph, K. Kamaladasa Source Type: research
A Review of Current Landscape and Definition of Septic Cardiomyopathy
This study examined the literature investigating SCM or cardiac dysfunction in sepsis and compared the various proposed diagnostic criteria for acute abnormalities and imaging parameters utilised. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: S. Sivapathan, B. Gehardy, F. Pathan, K. Negishi, S. Orde Source Type: research
A Shift to the Arm: A Single-Centre Comparative Analysis of Antecubital Fossa Versus Alternative Access for Right Heart Catheterisation
Right heart catheterisation (RHC) is conventionally performed via central venous access and carries a risk of access site complications, especially in those on anticoagulation. The antecubital fossa (ACF) vein is an increasingly utilised alternative, which may become the preferred access site for RHC if safety and feasibility can be proven. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: S. Rajapakse, K. Madan, J. Gunton, C. DePasquale, C. Burdeniuk Source Type: research
Acute Treatment With Antioxidant N-Propionylglycine Attenuates Mitochondrial Cysteine Redox Post-Translational Modifications and Restores Endogenous Antioxidants in the Diabetic Heart, Identified Using Quantitative Mass Spectrometry
Excessive production of reactive oxygen species (ROS) is a powerful shared mechanism in the pathogenesis of cardiovascular disease (CVD) and type 2 Diabetes (T2D). Reactive oxygen species overproduction reduces cellular antioxidant capacity and increases contractile dysfunction through protein oxidation. Clinically, the cumulative effect is increased mortality risk following a single, acute cardiac event in T2D cohorts [1]. Cysteine-containing proteins are at risk of oxidation, with protection afforded by protecting these sites with antioxidant therapies [2]. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: M. Talbot, A. Rookyard, D. Li, S. Cordwell, M. White Source Type: research
Aetiology of Heart Failure in Patients With Recovered Left Ventricular Ejection Fraction
Heart failure with recovered ejection fraction (HFrecEF) is defined as a reduction in ejection fraction (EF) that has subsequently improved to ≥50%. There are limited data on the type of heart failure aetiology most likely to recover and this study aimed to identify this. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: R. Velusamy, Y. Cheah, N. Sharma Source Type: research
An Epidemiological Study of Heart Failure: Delineating Patterns Among Ethnic Minority Groups
This study sought to profile differences in clinical characteristics among different ethnic groups with HF in order to better understand these subpopulations and their modifiable cardiovascular risk factors. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: M. Zaheen, H. Mohammed Abdul, G. Gan, T. Tan Source Type: research
An Omics-Based Screening Tool to Determine the Risk of Developing Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) has a variable penetrance of 50%. Half of all patients who are diagnosed with HCM will fail to develop a HCM phenotype throughout their lives. Omics is a useful tool for developing a diagnostics model for HCM and could enable the identification of patients who will develop HCM later in life. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: D. Reinke, E. Kristianto, M. Alsherbiny, L. Hool Source Type: research
Angiographic Findings in Patients With De Novo Heart Failure With Reduced Ejection Fraction (HFrEF) Referred for Early Inpatient Coronary Angiography During Their Index Admission
Ischaemic heart disease is the most common cause of HFrEF and portends a worse prognosis. Heart failure guidelines worldwide recommend coronary evaluation in new diagnoses of HFrEF; however, there is a scarcity of data guiding the optimal mode of coronary evaluation. The timing of coronary angiography and the benefit of subsequent coronary revascularisation in these patients, especially in the absence of angina, is contentious. Whether early inpatient angiography justifies the required resources and associated periprocedural risks needs to be evaluated. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: C. Mew, A. Camuglia, G. Malhotra, S. Cox Source Type: research
Association Between Age and Outcomes Following Catheter Ablation in AF-Mediated Cardiomyopathy
This study aimed to evaluate the impact of age on LV recovery and AF recurrence in AF-mediated cardiomyopathy (AFCM) following CA. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: L. Segan, D. Chieng, H. Sugumar, L. Ling, S. Azzopardi, Z. Nderitu, R. Parameswaran, A. Voskoboinik, A. McLellan, G. Lee, S. Joseph, M. Wong, A. Taylor, J. Kalman, P. Kistler, S. Prabhu Source Type: research
