Intraoperative assessment of cochlear nerve functionality in various vestibular schwannoma scenarios: Lessons learned
Hear Res. 2024 Mar 23;446:108997. doi: 10.1016/j.heares.2024.108997. Online ahead of print.ABSTRACTThe use of cochlear implants (CIs) is on the rise for patients with vestibular schwannoma (VS). Besides CI following tumor resection, new scenarios such as implantation in observed and/or irradiated tumors are becoming increasingly common. A significant emerging trend is the need of intraoperative evaluation of the functionality of the cochlear nerve in order to decide if a CI would be placed. The purpose of this paper is to explore the experience of a tertiary center with the application of the Auditory Nerve Test System (AN...
Source: Hearing Research - April 2, 2024 Category: Audiology Authors: Luis Lassaletta Miryam Calvino Miguel D íaz Jos é Manuel Morales-Puebla Isabel S ánchez-Cuadrado Isabel Varela-Nieto Javier Gavil án Source Type: research

Noise-induced synaptic loss and its post-exposure recovery in CBA/CaJ vs. C57BL/6J mice
Hear Res. 2024 Mar 23;445:108996. doi: 10.1016/j.heares.2024.108996. Online ahead of print.ABSTRACTAcute noise-induced loss of synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs) has been documented in several strains of mice, but the extent of post-exposure recovery reportedly varies dramatically. If such inter-strain heterogeneity is real, it could be exploited to probe molecular pathways mediating neural remodeling in the adult cochlea. Here, we compared synaptopathy repair in CBA/CaJ vs. C57BL/6J, which are at opposite ends of the reported recovery spectrum. We evaluated C57BL/6J mice 0 h, 24 h, 2...
Source: Hearing Research - March 28, 2024 Category: Audiology Authors: Pei-Zhe Wu Leslie D Liberman M Charles Liberman Source Type: research

Noise-induced synaptic loss and its post-exposure recovery in CBA/CaJ vs. C57BL/6J mice
Hear Res. 2024 Mar 23;445:108996. doi: 10.1016/j.heares.2024.108996. Online ahead of print.ABSTRACTAcute noise-induced loss of synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs) has been documented in several strains of mice, but the extent of post-exposure recovery reportedly varies dramatically. If such inter-strain heterogeneity is real, it could be exploited to probe molecular pathways mediating neural remodeling in the adult cochlea. Here, we compared synaptopathy repair in CBA/CaJ vs. C57BL/6J, which are at opposite ends of the reported recovery spectrum. We evaluated C57BL/6J mice 0 h, 24 h, 2...
Source: Hearing Research - March 28, 2024 Category: Audiology Authors: Pei-Zhe Wu Leslie D Liberman M Charles Liberman Source Type: research

Noise-induced synaptic loss and its post-exposure recovery in CBA/CaJ vs. C57BL/6J mice
Hear Res. 2024 Mar 23;445:108996. doi: 10.1016/j.heares.2024.108996. Online ahead of print.ABSTRACTAcute noise-induced loss of synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs) has been documented in several strains of mice, but the extent of post-exposure recovery reportedly varies dramatically. If such inter-strain heterogeneity is real, it could be exploited to probe molecular pathways mediating neural remodeling in the adult cochlea. Here, we compared synaptopathy repair in CBA/CaJ vs. C57BL/6J, which are at opposite ends of the reported recovery spectrum. We evaluated C57BL/6J mice 0 h, 24 h, 2...
Source: Hearing Research - March 28, 2024 Category: Audiology Authors: Pei-Zhe Wu Leslie D Liberman M Charles Liberman Source Type: research

Noise-induced synaptic loss and its post-exposure recovery in CBA/CaJ vs. C57BL/6J mice
Hear Res. 2024 Mar 23;445:108996. doi: 10.1016/j.heares.2024.108996. Online ahead of print.ABSTRACTAcute noise-induced loss of synapses between inner hair cells (IHCs) and auditory nerve fibers (ANFs) has been documented in several strains of mice, but the extent of post-exposure recovery reportedly varies dramatically. If such inter-strain heterogeneity is real, it could be exploited to probe molecular pathways mediating neural remodeling in the adult cochlea. Here, we compared synaptopathy repair in CBA/CaJ vs. C57BL/6J, which are at opposite ends of the reported recovery spectrum. We evaluated C57BL/6J mice 0 h, 24 h, 2...
Source: Hearing Research - March 28, 2024 Category: Audiology Authors: Pei-Zhe Wu Leslie D Liberman M Charles Liberman Source Type: research

Otoacoustic emissions in African mole-rats
Hear Res. 2024 Mar 19;445:108994. doi: 10.1016/j.heares.2024.108994. Online ahead of print.ABSTRACTAfrican mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear amplification. If true, this would make them unique among mammals. However, both theoretical considerations on the generation of DPOAE as well as previously published experimental ev...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Geoffrey A Manley Bert Maat Sabine Begall Pascal Malkemper Kai R Caspar Leif Moritz Pim van Dijk Source Type: research

Towards universal access: A review of global efforts in ear and hearing care
Hear Res. 2024 Feb 11;445:108973. doi: 10.1016/j.heares.2024.108973. Online ahead of print.ABSTRACTHearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbidity such as delayed language development, reduced educational attainment, and diminished social well-being. There is a need to augment prevention, early identification, treatment, and rehabilitation for these conditions. Expanded access to hearing screening, growth of the hearing health wor...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Rolvix H Patterson Olayinka Suleiman Racheal Hapunda Blake Wilson Shelly Chadha Debara Tucci Source Type: research

Otoacoustic emissions in African mole-rats
Hear Res. 2024 Mar 19;445:108994. doi: 10.1016/j.heares.2024.108994. Online ahead of print.ABSTRACTAfrican mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear amplification. If true, this would make them unique among mammals. However, both theoretical considerations on the generation of DPOAE as well as previously published experimental ev...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Geoffrey A Manley Bert Maat Sabine Begall Pascal Malkemper Kai R Caspar Leif Moritz Pim van Dijk Source Type: research

Towards universal access: A review of global efforts in ear and hearing care
Hear Res. 2024 Feb 11;445:108973. doi: 10.1016/j.heares.2024.108973. Online ahead of print.ABSTRACTHearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbidity such as delayed language development, reduced educational attainment, and diminished social well-being. There is a need to augment prevention, early identification, treatment, and rehabilitation for these conditions. Expanded access to hearing screening, growth of the hearing health wor...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Rolvix H Patterson Olayinka Suleiman Racheal Hapunda Blake Wilson Shelly Chadha Debara Tucci Source Type: research

Otoacoustic emissions in African mole-rats
Hear Res. 2024 Mar 19;445:108994. doi: 10.1016/j.heares.2024.108994. Online ahead of print.ABSTRACTAfrican mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear amplification. If true, this would make them unique among mammals. However, both theoretical considerations on the generation of DPOAE as well as previously published experimental ev...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Geoffrey A Manley Bert Maat Sabine Begall Pascal Malkemper Kai R Caspar Leif Moritz Pim van Dijk Source Type: research

Towards universal access: A review of global efforts in ear and hearing care
Hear Res. 2024 Feb 11;445:108973. doi: 10.1016/j.heares.2024.108973. Online ahead of print.ABSTRACTHearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbidity such as delayed language development, reduced educational attainment, and diminished social well-being. There is a need to augment prevention, early identification, treatment, and rehabilitation for these conditions. Expanded access to hearing screening, growth of the hearing health wor...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Rolvix H Patterson Olayinka Suleiman Racheal Hapunda Blake Wilson Shelly Chadha Debara Tucci Source Type: research

Otoacoustic emissions in African mole-rats
Hear Res. 2024 Mar 19;445:108994. doi: 10.1016/j.heares.2024.108994. Online ahead of print.ABSTRACTAfrican mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear amplification. If true, this would make them unique among mammals. However, both theoretical considerations on the generation of DPOAE as well as previously published experimental ev...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Geoffrey A Manley Bert Maat Sabine Begall Pascal Malkemper Kai R Caspar Leif Moritz Pim van Dijk Source Type: research

Towards universal access: A review of global efforts in ear and hearing care
Hear Res. 2024 Feb 11;445:108973. doi: 10.1016/j.heares.2024.108973. Online ahead of print.ABSTRACTHearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbidity such as delayed language development, reduced educational attainment, and diminished social well-being. There is a need to augment prevention, early identification, treatment, and rehabilitation for these conditions. Expanded access to hearing screening, growth of the hearing health wor...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Rolvix H Patterson Olayinka Suleiman Racheal Hapunda Blake Wilson Shelly Chadha Debara Tucci Source Type: research

Otoacoustic emissions in African mole-rats
Hear Res. 2024 Mar 19;445:108994. doi: 10.1016/j.heares.2024.108994. Online ahead of print.ABSTRACTAfrican mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear amplification. If true, this would make them unique among mammals. However, both theoretical considerations on the generation of DPOAE as well as previously published experimental ev...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Geoffrey A Manley Bert Maat Sabine Begall Pascal Malkemper Kai R Caspar Leif Moritz Pim van Dijk Source Type: research

Towards universal access: A review of global efforts in ear and hearing care
Hear Res. 2024 Feb 11;445:108973. doi: 10.1016/j.heares.2024.108973. Online ahead of print.ABSTRACTHearing loss affects 1.6 billion people worldwide and disproportionately affects those in low- and middle-income countries. Despite being largely preventable or treatable, ear and hearing conditions result in significant and lifelong morbidity such as delayed language development, reduced educational attainment, and diminished social well-being. There is a need to augment prevention, early identification, treatment, and rehabilitation for these conditions. Expanded access to hearing screening, growth of the hearing health wor...
Source: Hearing Research - March 23, 2024 Category: Audiology Authors: Rolvix H Patterson Olayinka Suleiman Racheal Hapunda Blake Wilson Shelly Chadha Debara Tucci Source Type: research