Vestibular receptors contribute to cortical auditory evoked potentials.
Abstract Acoustic sensitivity of the vestibular apparatus is well-established, but the contribution of vestibular receptors to the late auditory evoked potentials of cortical origin is unknown. Evoked potentials from 500 Hz tone pips were recorded using 70 channel EEG at several intensities below and above the vestibular acoustic threshold, as determined by vestibular evoked myogenic potentials (VEMPs). In healthy subjects both auditory mid- and long-latency auditory evoked potentials (AEPs), consisting of Na, Pa, N1 and P2 waves, were observed in the sub-threshold conditions. However, in passing through the vesti...
Source: Hearing Research - December 6, 2013 Category: Audiology Authors: Todd NP, Paillard AC, Kluk K, Whittle E, Colebatch JG Tags: Hear Res Source Type: research

Sensorineural hearing loss amplifies neural coding of envelope information in the central auditory system of chinchillas.
Abstract People with sensorineural hearing loss often have substantial difficulty understanding speech under challenging listening conditions. Behavioral studies suggest that reduced sensitivity to the temporal structure of sound may be responsible, but underlying neurophysiological pathologies are incompletely understood. Here, we investigate the effects of noise-induced hearing loss on coding of envelope (ENV) structure in the central auditory system of anesthetized chinchillas. ENV coding was evaluated noninvasively using auditory evoked potentials recorded from the scalp surface in response to sinusoidally amp...
Source: Hearing Research - December 4, 2013 Category: Audiology Authors: Zhong Z, Henry KS, Heinz MG Tags: Hear Res Source Type: research

Effects of cochlear ablation on amino acid levels in the rat cochlear nucleus and superior olive.
Abstract Amino acids have important roles in the chemistry of the auditory system, including communication among neurons. There is much evidence for glutamate as a neurotransmitter from auditory nerve fibers to cochlear nucleus neurons. Previous studies in rodents have examined effects of removal of auditory nerve input by cochlear ablation on levels, uptake and release of glutamate in cochlear nucleus subdivisions, as well as on glutamate receptors. Effects have also been reported on uptake and release of γ-aminobutyrate (GABA) and glycine, two other amino acids strongly implicated in cochlear nucleus synap...
Source: Hearing Research - November 28, 2013 Category: Audiology Authors: Godfrey DA, Jin YM, Liu X, Godfrey MA Tags: Hear Res Source Type: research

Narrow sound pressure level tuning in the auditory cortex of the bats Molossus molossus and Macrotus waterhousii.
A, Mora EC Abstract In the auditory system, tuning to sound level appears in the form of non-monotonic response-level functions that depict the response of a neuron to changing sound levels. Neurons with non-monotonic response-level functions respond best to a particular sound pressure level (defined as "best level" or level evoking the maximum response). We performed a comparative study on the location and basic functional organization of the auditory cortex in the gleaning bat, Macrotus waterhousii, and the aerial-hawking bat, Molossus molossus. Here, we describe the response-level function of cortica...
Source: Hearing Research - November 21, 2013 Category: Audiology Authors: Macías S, Hechavarría JC, Cobo A, Mora EC Tags: Hear Res Source Type: research

Electric-acoustic pitch comparisons in single-sided-deaf cochlear implant users: Frequency-place functions and rate pitch.
Abstract Eight cochlear implant users with near-normal hearing in their non-implanted ear compared pitch percepts for pulsatile electric and acoustic pure-tone stimuli presented to the two ears. Six subjects were implanted with a 31-mm MED-EL FLEXSOFT electrode, and two with a 24-mm medium (M) electrode, with insertion angles of the most apical contacts ranging from 565° to 758°. In the first experiment, frequency-place functions were derived from pure-tone matches to 1500-pps unmodulated pulse trains presented to individual electrodes and compared to Greenwood's frequencyposition map along the organ of Co...
Source: Hearing Research - November 16, 2013 Category: Audiology Authors: Schatzer R, Vermeire K, Visser D, Krenmayr A, Kals M, Voormolen M, Van de Heyning P, Clemens Z Tags: Hear Res Source Type: research

An Automated Psychoacoustic Testing Apparatus for Use in Cats.
We present a novel behavioral experimental system that was developed to allow efficient animal training in response to acoustic stimuli. Cats were required to perform a relatively simple task of moving toward and away from the device depending on whether the members of a tone pair were different or the same in frequency (go/no-go task). The experimental setup proved to be effective, with all animals (N = 7) performing at above 90% correct on an easy task. Animals were trained within 2 to 4 weeks and then generated a total of 150 to 200 trials per day, distributed within approximately 8 self initiated sessions. Data collect...
Source: Hearing Research - November 12, 2013 Category: Audiology Authors: Benovitski YB, Blamey PJ, Rathbone GD, Fallon JB Tags: Hear Res Source Type: research

Behavioral correlates of auditory streaming in rhesus macaques.
Abstract Perceptual representations of auditory stimuli (i.e., sounds) are derived from the auditory system's ability to segregate and group the spectral, temporal, and spatial features of auditory stimuli-a process called "auditory scene analysis". Psychophysical studies have identified several of the principles and mechanisms that underlie a listener's ability to segregate and group acoustic stimuli. One important psychophysical task that has illuminated many of these principles and mechanisms is the "streaming" task. Despite the wide use of this task to study psychophysical mechanisms of hum...
Source: Hearing Research - November 12, 2013 Category: Audiology Authors: Christison-Lagay KL, Cohen YE Tags: Hear Res Source Type: research

Left hemisphere fractional anisotropy increase in noise-induced tinnitus: A diffusion tensor imaging (DTI) study of white matter tracts in the brain.
Abstract Diffusion tensor imaging (DTI) is a contemporary neuroimaging modality used to study connectivity patterns and microstructure of white matter tracts in the brain. The use of DTI in the study of tinnitus is a relatively unexplored methodology with no studies focusing specifically on tinnitus induced by noise exposure. In this investigation, participants were two groups of adults matched for etiology, age, and degree of peripheral hearing loss, but differed by the presence or absence (+/-) of tinnitus. It is assumed that matching individuals on the basis of peripheral hearing loss, allows for differentiatin...
Source: Hearing Research - November 8, 2013 Category: Audiology Authors: Benson RR, Gattu R, Cacace AT Tags: Hear Res Source Type: research

Effects of electrical pulse polarity shape on intra cochlear neural responses in humans: Triphasic pulses with cathodic second phase.
Abstract To avoid a continuous charging of the stimulated tissue in auditory prostheses, charge-balanced pulses are used. In this context the effect of electrical pulse shape and polarity is still a matter of debate and the most effective pulse shape needs to be determined (Bahmer et al., 2010a; Undurraga et al., 2010; Wieringen et al., 2008; Macherey et al., 2008). Therefore, we conducted electrophysiological measurements, namely electrical compound action potentials (ECAPs) to assess response strength elicited by various pulse shapes and polarities in five cochlear implant recipients (SonataTI100/PulsarCI100 dev...
Source: Hearing Research - October 23, 2013 Category: Audiology Authors: Bahmer A, Baumann U Tags: Hear Res Source Type: research

Bone conduction in Thiel-embalmed cadaver heads.
CONCLUSION: Thiel-embalmed human whole-head specimens can be used as an alternative model for the study of human middle ear mechanics secondary to BC stimulation. At some frequencies, differences from living subjects must be considered. PMID: 24161399 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - October 22, 2013 Category: Audiology Authors: Guignard J, Stieger C, Kompis M, Caversaccio M, Arnold A Tags: Hear Res Source Type: research

Auditory cortical axons contact commissural cells throughout the guinea pig inferior colliculus.
Abstract Projections from auditory cortex (AC) affect how cells in both inferior colliculi (IC) respond to acoustic stimuli. The large projection from the AC to the ipsilateral IC is usually credited with the effects in the ipsilateral IC. The circuitry underlying effects in the contralateral IC is less clear. The direct projection from the AC to the contralateral IC is relatively small. An unexplored possibility is that the large ipsilateral cortical projection contacts the substantial number of cells in the ipsilateral IC that project through the commissure to the contralateral IC. Apparent contacts between cort...
Source: Hearing Research - October 17, 2013 Category: Audiology Authors: Nakamoto KT, Sowick CS, Schofield BR Tags: Hear Res Source Type: research

Exploring the role of auditory analysis in atypical compared to typical language development.
This article is part of a Special Issue entitled . PMID: 24112877 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - October 7, 2013 Category: Audiology Authors: Grube M, Cooper FE, Kumar S, Kelly T, Griffiths TD Tags: Hear Res Source Type: research

Stimulus frequency otoacoustic emissions evoked by swept tones.
Abstract Otoacoustic emissions (OAEs) are soft sounds generated by the cochlea and the measurements of OAEs are useful in detecting cochlear damages. Stimulus frequency otoacoustic emissions (SFOAEs) are evoked by one single tone and they are the most frequency specific in probing functional status of the cochlea than other types of OAEs. However, SFOAEs are currently restricted to research only because of the difficulty and low efficiency of their measurements. To solve these problems, an efficient method of using swept tones to measure SFOAEs was proposed in this study. The swept tones had time-varying frequenci...
Source: Hearing Research - October 7, 2013 Category: Audiology Authors: Chen S, Deng J, Bian L, Li G Tags: Hear Res Source Type: research

Neuronal basis of speech comprehension.
Abstract Verbal communication does not rely only on the simple perception of auditory signals. It is rather a parallel and integrative processing of linguistic and non-linguistic information, involving temporal and frontal areas in particular. This review describes the inherent complexity of auditory speech comprehension from a functional-neuroanatomical perspective. The review is divided into two parts. In the first part, structural and functional asymmetry of language relevant structures will be discus. The second part of the review will discuss recent neuroimaging studies, which coherently demonstrate that spee...
Source: Hearing Research - October 7, 2013 Category: Audiology Authors: Specht K Tags: Hear Res Source Type: research

Thalamocortical mechanisms for integrating musical tone and rhythm.
This article is part of a Special Issue entitled . PMID: 24103509 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - October 6, 2013 Category: Audiology Authors: Musacchia G, Large E, Schroeder CE Tags: Hear Res Source Type: research

ECAP Spread of Excitation with Virtual Channels and Physical Electrodes.
Abstract The primary goal of this study was to evaluate physiological spatial excitation patterns for stimulation of adjacent physical electrodes and intermediate virtual channels. Two experiments were conducted that utilized electrically evoked compound action potential (ECAP) spread-of-excitation (SOE) functions obtained with the traditional forward-masking subtraction method. These two experiments examined spatial excitation patterns for virtual-channel maskers and probes, respectively. In Experiment 1, ECAP SOE patterns were obtained for maskers applied to physical electrodes and virtual channels to determine ...
Source: Hearing Research - October 3, 2013 Category: Audiology Authors: Hughes ML, Stille LJ, Baudhuin JL, Goehring JL Tags: Hear Res Source Type: research

Mode-locking neurodynamics predict human auditory brainstem responses to musical intervals.
This article is part of a Special Issue entitled . PMID: 24091182 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - October 1, 2013 Category: Audiology Authors: Lerud KD, Almonte FV, Kim JC, Large EW Tags: Hear Res Source Type: research

Vertical-plane sound localization with distorted spectral cues.
Abstract For human listeners, the primary cues for localization in the vertical plane are provided by the direction-dependent filtering of the pinnae, head, and upper body. Vertical-plane localization generally is accurate for broadband sounds, but when such sounds are presented at near-threshold levels or at high levels with short durations (
Source: Hearing Research - September 27, 2013 Category: Audiology Authors: Macpherson EA, Sabin AT Tags: Hear Res Source Type: research

Auditory neuroimaging with fMRI and PET.
This article is part of a Special Issue entitled . PMID: 24076424 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 27, 2013 Category: Audiology Authors: Talavage TM, Gonzalez-Castillo J, Scott SK Tags: Hear Res Source Type: research

Phase effects in masking by harmonic complexes: Speech recognition.
Abstract Harmonic complexes that generate highly modulated temporal envelopes on the basilar membrane (BM) mask a tone less effectively than complexes that generate relatively flat temporal envelopes, because the non-linear active gain of the BM selectively amplifies a low-level tone in the dips of a modulated masker envelope. The present study examines a similar effect in speech recognition. Speech reception thresholds (SRTs) were measured for a voice masked by harmonic complexes with partials in sine phase (SP) or in random phase (RP). The masker's fundamental frequency (F0) was 50, 100 or 200 Hz. SRTs were...
Source: Hearing Research - September 27, 2013 Category: Audiology Authors: Deroche ML, Culling JF, Chatterjee M Tags: Hear Res Source Type: research

Examining neural plasticity and cognitive benefit through the unique lens of musical training.
Abstract Training programs aimed to alleviate or improve auditory-cognitive abilities have either experienced mixed success or remain to be fully validated. The limited benefits of such regimens are largely attributable to our weak understanding of (i) how (and which) interventions provide the most robust and long lasting improvements to cognitive and perceptual abilities and (ii) how the neural mechanisms which underlie such abilities are positively modified by certain activities and experience. Recent studies indicate that music training provides robust, long-lasting biological benefits to auditory function. Imp...
Source: Hearing Research - September 27, 2013 Category: Audiology Authors: Moreno S, Bidelman GM Tags: Hear Res Source Type: research

Editorial introduction to Hearing Research special issue on communication sounds and the brain: New directions and perspectives.
PMID: 24076210 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 24, 2013 Category: Audiology Authors: Petkov C, Gentner T, Liu RC Tags: Hear Res Source Type: research

Can nonlinguistic musical training change the way the brain processes speech? The expanded OPERA hypothesis.
Abstract A growing body of research suggests that musical training has a beneficial impact on speech processing (e.g., hearing of speech in noise and prosody perception). As this research moves forward two key questions need to be addressed: 1) Can purely instrumental musical training have such effects? 2) If so, how and why would such effects occur? The current paper offers a conceptual framework for understanding such effects based on mechanisms of neural plasticity. The expanded OPERA hypothesis proposes that when music and speech share sensory or cognitive processing mechanisms in the brain, and music places h...
Source: Hearing Research - September 19, 2013 Category: Audiology Authors: Patel AD Tags: Hear Res Source Type: research

Special issue in Hearing Research: Human auditory neuroimaging.
PMID: 24055073 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 18, 2013 Category: Audiology Authors: Hall DA, Langers DR Tags: Hear Res Source Type: research

Cochlear implantation for chronic electrical stimulation in the mouse.
We describe the surgical approach for implantation, as well as presenting the first functional data obtained from intracochlear electrical stimulation in the mouse. PMID: 24055621 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 18, 2013 Category: Audiology Authors: Irving S, Trotter MI, Fallon JB, Millard RE, Shepherd RK, Wise AK Tags: Hear Res Source Type: research

Age-related hearing loss patterns in Fischer 344/NHsd rats with cisplatin-induced hearing loss.
Abstract The current study was undertaken to explore the impact of cisplatin ototoxicity at a young adult age on the development of age-related hearing loss, both in terms of age of onset and severity of the hearing loss. For the study, 21 Fischer 344/NHsd rats were tested. All rats were tested for auditory brainstem responses (ABRs) at age 7 months and then 15 of the rats were exposed to 7 mg/kg cisplatin by intra-peritoneal infusion. The other 6 rats received saline infusions to serve as controls. Seven of the cisplatin rats were euthanized after an ABR test 7 days after cisplatin exposure to assess acute damage...
Source: Hearing Research - September 18, 2013 Category: Audiology Authors: Bielefeld EC Tags: Hear Res Source Type: research

Spatial release from masking improves sound pattern discrimination along a biologically relevant pulse-rate continuum in gray treefrogs.
Abstract Frogs form large choruses during the mating season in which males produce loud advertisement calls to attract females and repel rival males. High background noise levels in these social aggregations can impair vocal perception. In humans, spatial release from masking contributes to our ability to understand speech in noisy social groups. Here, we tested the hypothesis that spatial separation between target signals and 'chorus-shaped noise' improves the ability of female gray treefrogs (Hyla chrysoscelis) to perform a behavioral discrimination task based on perceiving differences in the pulsatile structure...
Source: Hearing Research - September 18, 2013 Category: Audiology Authors: Ward JL, Buerkle NP, Bee MA Tags: Hear Res Source Type: research

Multidimensional scaling between acoustic and electric stimuli in cochlear implant users with contralateral hearing.
This study investigated the perceptual relationship between acoustic and electric stimuli presented to CI users with functional contralateral hearing. Fourteen subjects with unilateral profound deafness implanted with a MED-EL CI scaled the perceptual differences between pure tones presented to the acoustic hearing ear and electric biphasic pulse trains presented to the implanted ear. The differences were analyzed with a multidimensional scaling (MDS) analysis. Additionally, speech performance in noise was tested using sentence material presented in different spatial configurations while patients listened with both their a...
Source: Hearing Research - September 18, 2013 Category: Audiology Authors: Vermeire K, Landsberger DM, Schleich P, Van de Heyning PH Tags: Hear Res Source Type: research

Objective measures of binaural masking level differences and comodulation masking release based on late auditory evoked potentials.
Abstract The audibility of important sounds is often hampered due to the presence of other masking sounds. The present study investigates if a correlate of the audibility of a tone masked by noise is found in late auditory evoked potentials measured from human listeners. The audibility of the target sound at a fixed physical intensity is varied by introducing auditory cues of (i) interaural target signal phase disparity and (ii) coherent masker level fluctuations in different frequency regions. In agreement with previous studies, psychoacoustical experiments showed that both stimulus manipulations result in a mask...
Source: Hearing Research - September 15, 2013 Category: Audiology Authors: Epp B, Yasin I, Verhey JL Tags: Hear Res Source Type: research

Transmission of bone conducted sound - Correlation between hearing perception and cochlear vibration.
ia C Abstract The vibration velocity of the lateral semicircular canal and the cochlear promontory was measured on 16 subjects with a unilateral middle ear common cavity, using a laser Doppler vibrometer, when the stimulation was by bone conduction (BC). Four stimulation positions were used: three ipsilateral positions and one contralateral position. Masked BC pure tone thresholds were measured with the stimulation at the same four positions. Valid vibration data were obtained at frequencies between 0.3 and 5.0 kHz. Large intersubject variation of the results was found with both methods. The difference in coc...
Source: Hearing Research - September 15, 2013 Category: Audiology Authors: Eeg-Olofsson M, Stenfelt S, Taghavi H, Reinfeldt S, Håkansson B, Tengstrand T, Finizia C Tags: Hear Res Source Type: research

Syllabic (∼2-5 Hz) and fluctuation (∼1-10 Hz) ranges in speech and auditory processing.
This article is part of a Special Issue entitled . PMID: 24035819 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 12, 2013 Category: Audiology Authors: Edwards E, Chang EF Tags: Hear Res Source Type: research

Neural sensitivity to statistical regularities as a fundamental biological process that underlies auditory learning: The role of musical practice.
This article is part of a Special Issue entitled . PMID: 24035820 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - September 12, 2013 Category: Audiology Authors: François C, Schön D Tags: Hear Res Source Type: research

Investigation of musicality in birdsong.
In conclusion, we suggest that birdsong research would benefit from current advances in music theory by attempting to identify structures that are designed to elicit listeners' emotions and then testing for such effects experimentally. Birdsong research that takes into account the striking complexity of song structure in light of its more immediate function - to affect behavioral state in listeners - could provide a useful animal model for studying basic principles of music neuroscience in a system that is very accessible for investigation, and where developmental auditory and social experience can be tightly controlled. T...
Source: Hearing Research - September 11, 2013 Category: Audiology Authors: Rothenberg D, Roeske TC, Voss HU, Naguib M, Tchernichovski O Tags: Hear Res Source Type: research

Off-Frequency Listening in Subjects with Chronic Tinnitus.
Abstract The occurrence of subjective tinnitus has been linked to cochlear damage, as most tinnitus patients have impaired hearing, and animal studies have shown that the induction of hearing loss can lead to behavioural signs of tinnitus. In tinnitus patients, the pure-tone audiogram is the main source of information about cochlear damage, but hearing thresholds alone may not adequately reflect its magnitude. Etchelecou et al. (2011) reported that the majority of patients with acute tinnitus post impulse noise exposure showed off-frequency listening (OFL), which is not readily observed in pure-tone audiograms. We...
Source: Hearing Research - September 4, 2013 Category: Audiology Authors: Kiani F, Yoganantha U, Tan CM, Meddis R, Schaette R Tags: Hear Res Source Type: research

Using naturalistic utterances to investigate vocal communication processing and development in human and non-human primates.
This article is part of a Special Issue entitled . PMID: 23994296 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 29, 2013 Category: Audiology Authors: Talkington WJ, Taglialatela JP, Lewis JW Tags: Hear Res Source Type: research

Function and plasticity of the medial olivocochlear system in musicians: a review.
Abstract The outer hair cells of the organ of Corti are the target of abundant efferent projections from the olivocochlear system. This peripheral efferent auditory subsystem is currently thought to be modulated by central activity via corticofugal descending auditory system, and to modulate active cochlear micromechanics. Although the function of this efferent subsystem remains unclear, physiological, psychophysical, and modeling data suggest that it may be involved in ear protection against noise damage and auditory perception, especially in the presence of background noise. Moreover, there is mounting evidence ...
Source: Hearing Research - August 29, 2013 Category: Audiology Authors: Perrot X, Collet L Tags: Hear Res Source Type: research

Understanding the neurophysiological basis of auditory abilities for social communication: A perspective on the value of ethological paradigms.
Abstract Acoustic communication between animals requires them to detect, discriminate, and categorize conspecific or heterospecific vocalizations in their natural environment. Laboratory studies of the auditory-processing abilities that facilitate these tasks have typically employed a broad range of acoustic stimuli, ranging from natural sounds like vocalizations to "artificial" sounds like pure tones and noise bursts. However, even when using vocalizations, laboratory studies often test abilities like categorization in relatively artificial contexts. Consequently, it is not clear whether neural and beha...
Source: Hearing Research - August 27, 2013 Category: Audiology Authors: Bennur S, Tsunada J, Cohen YE, Liu RC Tags: Hear Res Source Type: research

Biological impact of auditory expertise across the life span: musicians as a model of auditory learning.
Abstract Experience-dependent characteristics of auditory function, especially with regard to speech-evoked auditory neurophysiology, have garnered increasing attention in recent years. This interest stems from both pragmatic and theoretical concerns as it bears implications for the prevention and remediation of language-based learning impairment in addition to providing insight into mechanisms engendering experience-dependent changes in human sensory function. Musicians provide an attractive model for studying the experience-dependency of auditory processing in humans due to their distinctive neural enhancements ...
Source: Hearing Research - August 26, 2013 Category: Audiology Authors: Strait DL, Kraus N Tags: Hear Res Source Type: research

Attention to natural auditory signals.
Abstract The challenge of understanding how the brain processes natural signals is compounded by the fact that such signals are often tied closely to specific natural behaviors and natural environments. This added complexity is especially true for auditory communication signals that can carry information at multiple hierarchical levels, and often occur in the context of other competing communication signals. Selective attention provides a mechanism to focus processing resources on specific components of auditory signals, and simultaneously suppress responses to unwanted signals or noise. Although selective auditor...
Source: Hearing Research - August 24, 2013 Category: Audiology Authors: Caporello E, Gentner TQ Tags: Hear Res Source Type: research

Human auditory neuroimaging of intensity and loudness.
This article is part of a Special Issue entitled . PMID: 23973563 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 22, 2013 Category: Audiology Authors: Uppenkamp S, Röhl M Tags: Hear Res Source Type: research

Adaptation of the communicative brain to post-lingual deafness. Evidence from functional imaging.
Abstract Not having access to one sense profoundly modifies our interactions with the environment, in turn producing changes in brain organization. Deafness and its rehabilitation by cochlear implantation offer a unique model of brain adaptation during sensory deprivation and recovery. Functional imaging allows the study of brain plasticity as a function of the times of deafness and implantation. Even long after the end of the sensitive period for auditory brain physiological maturation, some plasticity may be observed. In this way the mature brain that becomes deaf after language acquisition can adapt to its modi...
Source: Hearing Research - August 21, 2013 Category: Audiology Authors: Lazard DS, Innes-Brown H, Barone P Tags: Hear Res Source Type: research

Spiral ganglion neuron quantification in the guinea pig cochlea using Confocal Laser Scanning Microscopy compared to embedding methods.
Abstract Neuron counting in the cochlea is a crucial but time-consuming operation for which various methods have been developed. To improve simplicity and efficiency, we tested an imaging method of the cochlea, and based on Confocal Laser Scanning Microscopy (CLSM), we visualised Rosenthal's Canal and quantified the spiral ganglion neurons (SGN) within. Cochleae of 8 normal hearing guinea pigs and one implanted with a silicone filament were fixed in paraformaldehyde (PFA), decalcified, dehydrated and cleared in Spalteholz solution. Using the tissue's autofluorescence, CLSM was performed at 100fold magnification ge...
Source: Hearing Research - August 20, 2013 Category: Audiology Authors: Wrzeszcz A, Reuter G, Nolte I, Lenarz T, Scheper V Tags: Hear Res Source Type: research

Functional imaging of auditory scene analysis.
This article is part of a Special Issue entitled . PMID: 23968821 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 19, 2013 Category: Audiology Authors: Gutschalk A, Dykstra A Tags: Hear Res Source Type: research

Pitch coding and pitch processing in the human brain.
This article is part of a Special Issue entitled . PMID: 23938209 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 11, 2013 Category: Audiology Authors: Plack CJ, Barker D, Hall DA Tags: Hear Res Source Type: research

Stimulus-dependent activations and attention-related modulations in the auditory cortex: A meta-analysis of fMRI studies.
Abstract We meta-analyzed 115 functional magnetic resonance imaging (fMRI) studies reporting auditory-cortex (AC) coordinates for activations related to the active and passive processing of the pitch and spatial location of non-speech sounds, as well as to the active and passive speech and voice processing. We aimed at revealing any systematic differences between AC surface locations of these activations by analyzing the activation loci statistically using the open-source Matlab toolbox VAMCA (Visualization and Meta-analysis on Cortical Anatomy). AC activations associated with pitch processing (e.g., active or pas...
Source: Hearing Research - August 9, 2013 Category: Audiology Authors: Alho K, Rinne T, Herron TJ, Woods DL Tags: Hear Res Source Type: research

Representation of frequency-modulated sounds in the human brain.
This article is part of a Special Issue entitled . PMID: 23933098 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 7, 2013 Category: Audiology Authors: Altmann CF, Gaese BH Tags: Hear Res Source Type: research

Cross-correlations between three units in cat primary auditory cortex.
Abstract Here we use a modification of the Joint-Peri-Stimulus-Time histogram (JPSTH) to investigate triple correlations between cat auditory cortex neurons. The modified procedure allowed the decomposition of the xy-pair correlation into a part that is due to the correlation of the x and y units with the trigger unit, and a remaining 'pair correlation'. We analyzed 16 sets of 15-minute duration stationary spontaneous recordings in primary auditory cortex (AI) with between 11 and 14 electrodes from 2 arrays of 8 electrodes each that provided spontaneous firing rates above 0.22 sp/s and for which reliable frequency...
Source: Hearing Research - August 7, 2013 Category: Audiology Authors: Eggermont JJ, Munguia R, Shaw G Tags: Hear Res Source Type: research

Explaining the high voice superiority effect in polyphonic music: Evidence from cortical evoked potentials and peripheral auditory models.
This article is part of a Special Issue entitled . PMID: 23916754 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 3, 2013 Category: Audiology Authors: Trainor LJ, Marie C, Bruce IC, Bidelman GM Tags: Hear Res Source Type: research

Assessment of rhythmic entrainment at multiple timescales in dyslexia: Evidence for disruption to syllable timing.
Assessment of rhythmic entrainment at multiple timescales in dyslexia: Evidence for disruption to syllable timing. Hear Res. 2013 Aug 2; Authors: Leong V, Goswami U Abstract Developmental dyslexia is associated with rhythmic difficulties, including impaired perception of beat patterns in music and prosodic stress patterns in speech. Spoken prosodic rhythm is cued by slow (
Source: Hearing Research - August 2, 2013 Category: Audiology Authors: Leong V, Goswami U Tags: Hear Res Source Type: research

Tonotopic mapping of human auditory cortex.
This article is part of a Special Issue entitled . PMID: 23916753 [PubMed - as supplied by publisher] (Source: Hearing Research)
Source: Hearing Research - August 2, 2013 Category: Audiology Authors: Saenz M, Langers DR Tags: Hear Res Source Type: research