Reported adverse events related to use of hepatitis C virus direct-acting antivirals with opioids: 2017 –2021
Due to concerns over potential interactions between some hepatitis C direct-acting antivirals (DAAs) and opioids, we describe adverse event (AE) reports of concomitant use of opioids and DAAs. (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - October 1, 2023 Category: Drugs & Pharmacology Authors: Anthony Martinez, Tipu Khan, Douglas E. Dylla, John Marcinak, Michelle Collins, Brad Saget and Brian Conway Tags: Brief Report Source Type: research

Reducing the harms of xylazine: clinical approaches, research deficits, and public health context
Xylazine has emerged as a consistent part of the unregulated drug supply in recent months. We discuss major domains of xylazine ’s harm, current knowledge deficits, clinical and harm reduction strategies for mi... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 30, 2023 Category: Drugs & Pharmacology Authors: Claire M. Zagorski, Rebecca A. Hosey, Christopher Moraff, Aaron Ferguson, Mary Figgatt, Shoshana Aronowitz, Natalie E. Stahl, Lucas G. Hill, Zoe McElligott and Nabarun Dasgupta Tags: Perspective Source Type: research

Managing high-risk behaviours and challenges to prevent housing loss in permanent supportive housing: a rapid review
Permanent supportive housing is an effective intervention for stably housing most people experiencing homelessness and mental illness who have complex support needs. However, high-risk behaviours and challenge... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 29, 2023 Category: Drugs & Pharmacology Authors: Nick Kerman, Sean A. Kidd, Christina Mutschler, John Sylvestre, Benjamin F. Henwood, Abe Oudshoorn, Carrie Anne Marshall, Tim Aubry and Vicky Stergiopoulos Tags: Review Source Type: research

How an emergency department is organized to provide opioid-specific harm reduction and facilitators and barriers to harm reduction implementation: a systems perspective
The intersection of dual public health emergencies —the COVID-19 pandemic and the drug toxicity crisis—has led to an urgent need for acute care based harm reduction for unregulated opioid use. Emergency Departm... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 21, 2023 Category: Drugs & Pharmacology Authors: Sunny Jiao, Vicky Bungay, Emily Jenkins and Marilou Gagnon Tags: Research Source Type: research

High willingness to use overdose prevention sites among suburban people who use drugs who do not inject
Overdose prevention sites (OPS) are evidence-based interventions to improve public health, yet implementation has been limited in the USA due to a variety of legal impediments. Studies in various US settings h... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 21, 2023 Category: Drugs & Pharmacology Authors: Kristin E. Schneider, Glenna J. Urquhart, Saba Rouhani, Sean T. Allen, Miles Morris and Susan G. Sherman Tags: Brief Report Source Type: research

International harm reduction indicators are still not reached: results from a repeated cross-sectional study on drug paraphernalia distribution in Germany, 2021
To prevent the transmission of blood-borne infections and reach the elimination of viral hepatitis by 2030, the World Health Organization (WHO) has set the goal to distribute 300 sterile needles and syringes e... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 19, 2023 Category: Drugs & Pharmacology Authors: Franziska Hommes, Amrei Krings, Achim D örre, Esther Neumeier, Dirk Schäffer and Ruth Zimmermann Tags: Research Source Type: research

Opioid relapse and its predictors among methadone maintenance patients: a multicenter, cross-sectional study in Vietnam
This study measured the opioid relapse rate and its associated factors am... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 16, 2023 Category: Drugs & Pharmacology Authors: Huong Thi Thanh Nguyen and Dai Xuan Dinh Tags: Research Source Type: research

Doing community-based research during dual public health emergencies (COVID and overdose)
Meaningful engagement and partnerships with people who use drugs are essential to conducting research that is relevant and impactful in supporting desired outcomes of drug consumption as well as reducing drug-... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 15, 2023 Category: Drugs & Pharmacology Authors: Phoenix Beck McGreevy, Shawn Wood, Erica Thomson, Charlene Burmeister, Heather Spence, Josh Pelletier, Willow Giesinger, Jenny McDougall, Rebecca McLeod, Abby Hutchison, Kurt Lock, Alexa Norton, Brittany Barker, Karen Urbanoski, Amanda Slaunwhite, Bohdan Tags: Methodology Source Type: research

Stigma and level of familiarity with opioid maintenance treatment (OMT) among specialist physicians in Israel
Opioid use disorder (OUD) poses significant public health problems that have increased dramatically, resulting in high rates of morbidity and mortality. (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 15, 2023 Category: Drugs & Pharmacology Authors: Rozner Lihi, Delayahu Yael, Brill Silviu, Sason Anat, Weinstein Marsha, Shoshan Stacy, Schreiber Shaul, Adelson Miriam and Peles Einat Tags: Research Source Type: research

Racial disparities in use of syringe service programs in King County, WA: a comparison of two cross-sectional surveys
Syringe service programs (SSPs) provide tools to people who inject drugs (PWID) to prevent overdose, reduce the risk of HIV and HCV infection, and reduce injection frequency. While effective, previous research... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 14, 2023 Category: Drugs & Pharmacology Authors: Katheryn Salow, Helen E. Jack, Joe Tinsley, Caleb J. Banta-Green, Susan Kingston, Matthew Iles-Shih, Judith I. Tsui and Sara Glick Tags: Research Source Type: research

Perceptions, intentions, and actual use of a consumer nicotine gum
Little is known about perceptions, use intentions, and behaviors of adults regarding nicotine gum that is marketed and regulated as a consumer product rather than as a medicinal nicotine replacement therapy (N... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 13, 2023 Category: Drugs & Pharmacology Authors: Cheryl K. Olson, Neil Sherwood, Maia Berkane, Karin Gilligan and Willie J. McKinney Jr. Tags: Research Source Type: research

People who inject oral morphine favor experimentation with injectable opioid substitution
The French Addictovigilance network has observed the existence of the intravenous use of oral morphine capsules among people suffering from opioid use disorders. According to persons who inject morphine, these... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 12, 2023 Category: Drugs & Pharmacology Authors: C élian Bertin, Philémon Dècle, Pierre Chappard, Perrine Roux and Nicolas Authier Tags: Research Source Type: research

Public health impact and harm reduction implications of xylazine-involved overdoses: a narrative review
Xylazine, an α2-adrenoceptor agonist sedative commonly used in veterinary medicine, is not approved for human use. Nevertheless, xylazine-involved overdose rates have surged in recent years, fueled by an incre... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 12, 2023 Category: Drugs & Pharmacology Authors: David T. Zhu Tags: Review Source Type: research

“It’s like a safety net for when things go wrong”: key stakeholder and program user perspectives on a peer-led safe space program in Sydney, Australia
Safe Spaces are a harm reduction approach commonly utilised in nightlife and festival settings to address alcohol and other drug-related harms. Despite increasing use, there has been little independent evaluat... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 9, 2023 Category: Drugs & Pharmacology Authors: Phillip Wadds, Christopher M. Doran, Anthony Shakeshaft and Dam Anh Tran Tags: Research Source Type: research

“Just another thing for me to stress off of”: Responses to unintentional fentanyl use in a community-based study of people who use opioids
The unintentional consumption of fentanyl is a serious health risk for people who use illicit drugs. In an ongoing community-based study regarding polysubstance use among people who use opioids, we found that ... (Source: Harm Reduction Journal)
Source: Harm Reduction Journal - September 8, 2023 Category: Drugs & Pharmacology Authors: Jennifer Lorvick, Jordana L. Hemberg, Madeleine J. George, Joy R. Piontak and Megan L. Comfort Tags: Research Source Type: research