PREDICT-GTN 2: Two-factor streamlined models match FIGO performance in gestational trophoblastic neoplasia
CONCLUSIONS: Our streamlined models could be used to assess GTN patients and replace FIGO, statistically matching performance. Given the importance of imaging parameters in guiding treatment, M2 and M3 are favoured for ongoing validation. In resource-poor countries, where access to specialist centres is problematic, M1 could be pragmatically implemented. Further prospective validation on a larger cohort is recommended.PMID:38091775 | DOI:10.1016/j.ygyno.2023.11.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 13, 2023 Category: Cancer & Oncology Authors: Victoria L Parker Matthew C Winter John A Tidy Julia E Palmer Naveed Sarwar Kamaljit Singh Xianne Aguiar Barry W Hancock Allan A Pacey Michael J Seckl Robert F Harrison Source Type: research
Mixed-method approach to informing a lifestyle intervention to improve the survivorship of patients with endometrial cancer
CONCLUSION: ECS are a disparate population, with worsening behaviors and mental health following the pandemic. The identified ECS-specific barriers and facilitators to behavioral intervention participation are being used to simultaneously improve the reach of and adherence to a lifestyle intervention aimed at improving their health and QoL.PMID:38091776 | DOI:10.1016/j.ygyno.2023.11.028 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 13, 2023 Category: Cancer & Oncology Authors: Shannon D Armbruster Katie Brow Tonja Locklear Mary Frazier Samantha M Harden Source Type: research
Corrigendum to "Metastasis-associated protein 1, modulated by miR-30c, promotes endometrial cancer progression through AKT/mTOR/4E-BP1 pathway" [Gynecol Oncol. 2019 Jul;154(1):207-217. doi: 10.1016/j.ygyno.2019.04.005. Epub 2019 Apr 9]
Gynecol Oncol. 2023 Dec 12;180:168-169. doi: 10.1016/j.ygyno.2023.11.035. Online ahead of print.NO ABSTRACTPMID:38091777 | DOI:10.1016/j.ygyno.2023.11.035 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 13, 2023 Category: Cancer & Oncology Authors: Xiaofeng Xu Xiangyi Kong Tao Liu Ling Zhou Jun Wu Jian Fu Yijin Wang Mengjing Zhu Shuang Yao Yue Ding Ling Ding Rong Li Xianghong Zhu Xiaoqiu Tang Yan Zhang Qian Yang Jingxian Ling Huaijun Zhou Source Type: research
Genomic characterization of vulvar squamous cell carcinoma reveals differential gene expression based on clinical outcome
CONCLUSIONS: ACVR2A and TGM3 are significantly under-expressed in tumors with poor outcome, suggesting they may play a role in tumor suppression. Clinical outcome of VSCC appears independent of MSI, TMB, or PD-L1 status.PMID:38086165 | DOI:10.1016/j.ygyno.2023.11.026 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 12, 2023 Category: Cancer & Oncology Authors: Mary E Gordinier Geoffrey F Schau Shanna B Pollock Lisa B E Shields Sameer Talwalkar Source Type: research
Practice patterns, time trends and quality of care of uterine cancer in Belgium: An analysis of the EFFECT database
CONCLUSIONS: Study results indicate an overall good quality of care for patients with uterine cancer in Belgium. Treatment areas with potential room for improvement include the use of minimally invasive surgery, comprehensive surgical staging and adjuvant therapy, which confirms the remaining controversies in uterine cancer treatment and the need for further research.PMID:38086166 | DOI:10.1016/j.ygyno.2023.11.015 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 12, 2023 Category: Cancer & Oncology Authors: Joren Vanbraband Nancy Van Damme Geert Silversmit Anke De Geyndt Gauthier Bouche Gerd Jacomen Eric de Jonge Fr édéric Goffin Hannelore Denys Fr édéric Amant Source Type: research
