Corrigendum to "Liver transcriptomic and proteomic analyses provide new insight into the pathogenesis of liver fibrosis in mice" [Genomics, Volume 115, Issue 6, November 2023, 110738]
Genomics. 2023 Dec 15:110760. doi: 10.1016/j.ygeno.2023.110760. Online ahead of print.NO ABSTRACTPMID:38103942 | DOI:10.1016/j.ygeno.2023.110760 (Source: Genomics)
Source: Genomics - December 16, 2023 Category: Genetics & Stem Cells Authors: Lili Zhang Qiumei Zhou Jiafu Zhang Kefeng Cao Chang Fan Sen Chen Hui Jiang Furong Wu Source Type: research

A novel link between circPDE3B and ferroptosis in esophageal squamous cell carcinoma progression
CONCLUSION: In summary, circPDE3B promotes ESCC progression by suppressing ferroptosis through recruiting HNRNPK/SLC7A11 and miR-516b-5p/CBS axes.PMID:38092323 | DOI:10.1016/j.ygeno.2023.110761 (Source: Genomics)
Source: Genomics - December 13, 2023 Category: Genetics & Stem Cells Authors: Pengli Zhou Zhengyang Wu Qinghui Zhang Ling Wang Wenguang Zhang Xinwei Han Source Type: research

A novel link between circPDE3B and ferroptosis in esophageal squamous cell carcinoma progression
CONCLUSION: In summary, circPDE3B promotes ESCC progression by suppressing ferroptosis through recruiting HNRNPK/SLC7A11 and miR-516b-5p/CBS axes.PMID:38092323 | DOI:10.1016/j.ygeno.2023.110761 (Source: Genomics)
Source: Genomics - December 13, 2023 Category: Genetics & Stem Cells Authors: Pengli Zhou Zhengyang Wu Qinghui Zhang Ling Wang Wenguang Zhang Xinwei Han Source Type: research

A novel link between circPDE3B and ferroptosis in esophageal squamous cell carcinoma progression
CONCLUSION: In summary, circPDE3B promotes ESCC progression by suppressing ferroptosis through recruiting HNRNPK/SLC7A11 and miR-516b-5p/CBS axes.PMID:38092323 | DOI:10.1016/j.ygeno.2023.110761 (Source: Genomics)
Source: Genomics - December 13, 2023 Category: Genetics & Stem Cells Authors: Pengli Zhou Zhengyang Wu Qinghui Zhang Ling Wang Wenguang Zhang Xinwei Han Source Type: research

DOT1L decelerates the development of osteoporosis by inhibiting SRSF1 transcriptional activity via microRNA-181-mediated KAT2B inhibition
CONCLUSION: DOT1L overexpression slowed down bone loss and promoted bone formation via the miR-181/KAT2B/SRSF1 axis, thereby alleviating OP development.PMID:38072145 | DOI:10.1016/j.ygeno.2023.110759 (Source: Genomics)
Source: Genomics - December 10, 2023 Category: Genetics & Stem Cells Authors: Changsheng Wang Rongsheng Chen Xitian Zhu Xiaobo Zhang Nancheng Lian Source Type: research

DOT1L decelerates the development of osteoporosis by inhibiting SRSF1 transcriptional activity via microRNA-181-mediated KAT2B inhibition
CONCLUSION: DOT1L overexpression slowed down bone loss and promoted bone formation via the miR-181/KAT2B/SRSF1 axis, thereby alleviating OP development.PMID:38072145 | DOI:10.1016/j.ygeno.2023.110759 (Source: Genomics)
Source: Genomics - December 10, 2023 Category: Genetics & Stem Cells Authors: Changsheng Wang Rongsheng Chen Xitian Zhu Xiaobo Zhang Nancheng Lian Source Type: research

DOT1L decelerates the development of osteoporosis by inhibiting SRSF1 transcriptional activity via microRNA-181-mediated KAT2B inhibition
CONCLUSION: DOT1L overexpression slowed down bone loss and promoted bone formation via the miR-181/KAT2B/SRSF1 axis, thereby alleviating OP development.PMID:38072145 | DOI:10.1016/j.ygeno.2023.110759 (Source: Genomics)
Source: Genomics - December 10, 2023 Category: Genetics & Stem Cells Authors: Changsheng Wang Rongsheng Chen Xitian Zhu Xiaobo Zhang Nancheng Lian Source Type: research

Expression profiles of lncRNAs, miRNAs, and mRNAs and interaction analysis indicates their potential involvment during testicular fusion in Spodoptera litura
Genomics. 2023 Dec 6:110758. doi: 10.1016/j.ygeno.2023.110758. Online ahead of print.ABSTRACTTesticular fusion of Spodoptera litura occures during metamorphosis, which benefits sperms development. Previous research identified involvement of ECM-integrin interaction pathways, MMPs in testicular fusion, but the regulatory mechanism remains unclear. RNA-seq was performed to analyze long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in testes, aiming to uncover potential regulatory mechanisms of testicular fusion. 2150 lncRNAs, 2742 targeted mRNAs, and 347 miRNAs were identified in testes at three different developmental st...
Source: Genomics - December 8, 2023 Category: Genetics & Stem Cells Authors: Yaqing Chen Yu Chen Xiaoqiang Yu Qili Feng Xiaoyun Wang Lin Liu Source Type: research

Expression profiles of lncRNAs, miRNAs, and mRNAs and interaction analysis indicates their potential involvment during testicular fusion in Spodoptera litura
Genomics. 2023 Dec 6:110758. doi: 10.1016/j.ygeno.2023.110758. Online ahead of print.ABSTRACTTesticular fusion of Spodoptera litura occures during metamorphosis, which benefits sperms development. Previous research identified involvement of ECM-integrin interaction pathways, MMPs in testicular fusion, but the regulatory mechanism remains unclear. RNA-seq was performed to analyze long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in testes, aiming to uncover potential regulatory mechanisms of testicular fusion. 2150 lncRNAs, 2742 targeted mRNAs, and 347 miRNAs were identified in testes at three different developmental st...
Source: Genomics - December 8, 2023 Category: Genetics & Stem Cells Authors: Yaqing Chen Yu Chen Xiaoqiang Yu Qili Feng Xiaoyun Wang Lin Liu Source Type: research

Expression profiles of lncRNAs, miRNAs, and mRNAs and interaction analysis indicates their potential involvment during testicular fusion in Spodoptera litura
Genomics. 2023 Dec 6:110758. doi: 10.1016/j.ygeno.2023.110758. Online ahead of print.ABSTRACTTesticular fusion of Spodoptera litura occures during metamorphosis, which benefits sperms development. Previous research identified involvement of ECM-integrin interaction pathways, MMPs in testicular fusion, but the regulatory mechanism remains unclear. RNA-seq was performed to analyze long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in testes, aiming to uncover potential regulatory mechanisms of testicular fusion. 2150 lncRNAs, 2742 targeted mRNAs, and 347 miRNAs were identified in testes at three different developmental st...
Source: Genomics - December 8, 2023 Category: Genetics & Stem Cells Authors: Yaqing Chen Yu Chen Xiaoqiang Yu Qili Feng Xiaoyun Wang Lin Liu Source Type: research

Using two self-developed InDel panels to explore forensic feature and population genetic structure in the Hui group
Genomics. 2023 Dec 5:110756. doi: 10.1016/j.ygeno.2023.110756. Online ahead of print.ABSTRACTTo address the challenges faced by forensic examiners in degraded DNA analysis, we have developed two different panels for various forensic applications, encompassing the AIM-InDel panel for ancestry inference and the Multi-InDel panel for individual identification, respectively. Herein, the efficiencies of these two panels were tested in the Chinese Hui group. By calculating forensic parameters and simulating family relationships, we verified that the Multi-InDel panel could be an effective tool for individual identification, pate...
Source: Genomics - December 7, 2023 Category: Genetics & Stem Cells Authors: Xi Yuan Xi Wang Qiong Lan Shuanglin Li Yifeng Lin Ming Zhao Hui Xu Fanzhang Lei Chunmei Shen Bofeng Zhu Source Type: research

Sex-specific transcriptome of the chicken chorioallantoic membrane
This study provides evidence that gene expression of extra-embryonic membranes is differentially regulated between male and female embryos. As such a better characterisation of associated mechanisms should facilitate the identification of new sex-specific biomarkers.PMID:38061480 | DOI:10.1016/j.ygeno.2023.110754 (Source: Genomics)
Source: Genomics - December 7, 2023 Category: Genetics & Stem Cells Authors: Maeva Halgrain Nelly Bernardet Christelle Hennequet-Antier Sophie R éhault-Godbert Source Type: research

RNA-Seq profiling of circular RNAs in mice with lipopolysaccharide-induced acute lung injury
In this study, circRNA profiles are remarkably changed in mice with LPS-triggered ALI, and their potential contribution to the disease is revealed.PMID:38061481 | DOI:10.1016/j.ygeno.2023.110755 (Source: Genomics)
Source: Genomics - December 7, 2023 Category: Genetics & Stem Cells Authors: Xianxian Jia Jinhui Huang Bo Wu Miao Yang Wei Xu Source Type: research

Whole genome sequencing of Crassostrea ariakensis (Mollusca: Ostreidae) and C. hongkongensis expands understandings of stress resistance in sessile oysters
Genomics. 2023 Dec 5:110757. doi: 10.1016/j.ygeno.2023.110757. Online ahead of print.ABSTRACTTo understand the environmental adaptations among sessile bivalves lacking adaptive immunity, a series of analyses were conducted, with special emphasis on the widely distributed C. ariakensis. Employing Pacbio sequencing and Hi-C technologies, whole genome for each of a C. ariakensis (southern China) and C. hongkongensis individual was generated, with the contig N50 reaching 6.2 and 13.0 Mb, respectively. Each genome harbored over 30,000 protein-coding genes, with approximately half of each genome consisting of repeats. Genome ali...
Source: Genomics - December 7, 2023 Category: Genetics & Stem Cells Authors: Xingzhi Zhang Junliang Guan Ming Zou Pingping He Li Zhang Yongxian Chen Wei Li Dapeng Wang Ermeng Yu Fangjie Zhong Peng Zhu Xueyu Yan Youhou Xu Bang Luo Ting Huang Linyuan Jiang Pinyuan Wei Jinxia Peng Source Type: research

Using two self-developed InDel panels to explore forensic feature and population genetic structure in the Hui group
Genomics. 2023 Dec 5:110756. doi: 10.1016/j.ygeno.2023.110756. Online ahead of print.ABSTRACTTo address the challenges faced by forensic examiners in degraded DNA analysis, we have developed two different panels for various forensic applications, encompassing the AIM-InDel panel for ancestry inference and the Multi-InDel panel for individual identification, respectively. Herein, the efficiencies of these two panels were tested in the Chinese Hui group. By calculating forensic parameters and simulating family relationships, we verified that the Multi-InDel panel could be an effective tool for individual identification, pate...
Source: Genomics - December 7, 2023 Category: Genetics & Stem Cells Authors: Xi Yuan Xi Wang Qiong Lan Shuanglin Li Yifeng Lin Ming Zhao Hui Xu Fanzhang Lei Chunmei Shen Bofeng Zhu Source Type: research