The cohesin complex in mammalian meiosis
In mammalian meiosis, distinct types of cohesin complexes are produced by altering the combination of meiosis ‐specific subunits. The meiosis‐specific subunits endow the cohesin complex with specific functions for numerous meiosis‐associated chromosomal events. This review mainly focuses on the cohesin complex in mammalian meiosis, pointing out the differences in its roles from those in mitosis. AbstractCohesin is an evolutionary conserved multi ‐protein complex that plays a pivotal role in chromosome dynamics. It plays a role both in sister chromatid cohesion and in establishing higher order chromosome architectur...
Source: Genes to Cells - November 27, 2018 Category: Genetics & Stem Cells Authors: Kei ‐ichiro Ishiguro Tags: REVIEW ARTICLE Source Type: research

A murine model of acute lung injury identifies growth factors to promote tissue repair and their biomarkers
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Source: Genes to Cells - November 25, 2018 Category: Genetics & Stem Cells Authors: Takeyuki Kurosawa, Shion Miyoshi, Soh Yamazaki, Takashi Nishina, Tetuo Mikami, Akira Oikawa, Sakae Homma, Hiroyasu Nakano Tags: Original Article Source Type: research

Nucleus ‐localized adiponectin is survival gate keeper through miR‐214‐mediated AIFM2 regulation
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Source: Genes to Cells - November 25, 2018 Category: Genetics & Stem Cells Authors: Junkwon Cho, Rika Teshigawara, Masahiro Kameda, Shinpei Yamaguchi, Takashi Tada Tags: Original Article Source Type: research

Transgenerational lipid ‐reducing activity of benzylisoquinoline alkaloids in Caenorhabditis elegans
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Source: Genes to Cells - November 19, 2018 Category: Genetics & Stem Cells Authors: Yit ‐Lai Chow, Fumihiko Sato Tags: Original Article Source Type: research

Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl ‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced Parkinson’s model mice
Enhanced level of CRMP2 phosphorylation at S522 is observed in SNc dopaminergic neurons of a MPTP mouse model of Parkinson ’s disease (PD). Genetic inhibition of CRMP2 phosphorylation (Crmp2 knock‐in) suppresses the reduction of striatal TH protein level and motor impairment in the PD mouse model. AbstractParkinson's disease (PD) is a common neurodegenerative disorder characterized by slow and progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Levodopa (l‐Dopa), the current main treatment for PD, supplies dopamine, but it does not prevent neurodegeneration. There is thus no ...
Source: Genes to Cells - November 18, 2018 Category: Genetics & Stem Cells Authors: Kentaro Togashi, Masaya Hasegawa, Jun Nagai, Aine Tonouchi, Daiki Masukawa, Kenneth Hensley, Yoshio Goshima, Toshio Ohshima Tags: ORIGINAL ARTICLE Source Type: research

Albatross/FBF1 contributes to both centriole duplication and centrosome separation
Protein –protein interactions involved in the centrosome cycle (Adapted from “Regulating the transition from centriole to basal body”, The Journal of Cell Biology, Vol. 193, No. 3, p436). Full‐length Albatross was confirmed to contribute to ciliation (1), and the C‐terminus and the N‐terminus of Albatross were found to interact with the Plk4‐STIL‐HsSAS‐6 complex and Plk1 for centriole duplication (2) and centrosome separation (3), respectively. AbstractThe centrosome is a small but important organelle that participates in centriole duplication, spindle formation, and ciliogenesis. Each event is regulated ...
Source: Genes to Cells - November 13, 2018 Category: Genetics & Stem Cells Authors: Akihito Inoko, Tomoki Yano, Tatsuo Miyamoto, Shinya Matsuura, Tohru Kiyono, Naoki Goshima, Masaki Inagaki, Yuko Hayashi Tags: ORIGINAL ARTICLE Source Type: research

Comprehensive and cell type ‐based characterization of the dorsal midbrain during development
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Source: Genes to Cells - November 13, 2018 Category: Genetics & Stem Cells Authors: Nariko Arimura, Ken ‐ichi Dewa, Mako Okada, Yuchio Yanagawa, Shin‐ichiro Taya, Mikio Hoshino Tags: Original Article Source Type: research

Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data
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Source: Genes to Cells - November 12, 2018 Category: Genetics & Stem Cells Authors: Kentaro Kawata, Katsuyuki Yugi, Atsushi Hatano, Toshiya Kokaji, Yoko Tomizawa, Masashi Fujii, Shinsuke Uda, Hiroyuki Kubota, Masaki Matsumoto, Keiichi I. Nakayama, Shinya Kuroda Tags: Original Article Source Type: research

Meiosis ‐specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope
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Source: Genes to Cells - November 11, 2018 Category: Genetics & Stem Cells Authors: Jagadeeswara Rao Bommi, H. D. Prasada Rao, Kiran Challa, Mika Higashide, Kaori Shinmyozu, Jun ‐ichi Nakayama, Miki Shinohara, Akira Shinohara Tags: Brief Report Source Type: research

Pyruvic acid/ethyl pyruvate inhibits melanogenesis in B16F10 melanoma cells through PI3K/AKT, GSK3 β, and ROS‐ERK signaling pathways
This article is protected by copyright. All rights reserved. (Source: Genes to Cells)
Source: Genes to Cells - November 11, 2018 Category: Genetics & Stem Cells Authors: Siqi Zhou, Kazuichi Sakamoto Tags: Original Article Source Type: research

Meiosis ‐specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope
This article is protected by copyright. All rights reserved. (Source: Genes to Cells)
Source: Genes to Cells - November 11, 2018 Category: Genetics & Stem Cells Authors: Jagadeeswara Rao Bommi, H. D. Prasada Rao, Kiran Challa, Mika Higashide, Kaori Shinmyozu, Jun ‐ichi Nakayama, Miki Shinohara, Akira Shinohara Tags: Brief Report Source Type: research

Pyruvic acid/ethyl pyruvate inhibits melanogenesis in B16F10 melanoma cells through PI3K/AKT, GSK3 β, and ROS‐ERK signaling pathways
This article is protected by copyright. All rights reserved. (Source: Genes to Cells)
Source: Genes to Cells - November 11, 2018 Category: Genetics & Stem Cells Authors: Siqi Zhou, Kazuichi Sakamoto Tags: Original Article Source Type: research

Issue Information
Genes to Cells,Volume 23, Issue 11, Page 933-937, November 2018. (Source: Genes to Cells)
Source: Genes to Cells - November 5, 2018 Category: Genetics & Stem Cells Source Type: research