Potential of an anti-bevacizumab idiotype scFv DNA-based immunization to elicit VEGF-binding antibody response
Gene Therapy, Published online: 08 December 2022; doi:10.1038/s41434-022-00376-9Potential of an anti-bevacizumab idiotype scFv DNA-based immunization to elicit VEGF-binding antibody response (Source: Gene Therapy)
Source: Gene Therapy - December 8, 2022 Category: Genetics & Stem Cells Authors: T ábata Almeida Silva Rodrigo Barbosa Aguiar Marcelo Mori Gabriel Esquitini Machado Barbara Hamaguchi Marcelo Ferreira Marcondes Machado Jane Zveiter Moraes Source Type: research
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model
Gene Therapy, Published online: 01 December 2022; doi:10.1038/s41434-022-00375-wIn vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model (Source: Gene Therapy)
Source: Gene Therapy - December 1, 2022 Category: Genetics & Stem Cells Authors: Yi A. Chen Mark W. Kankel Sam Hana Shukkwan Kelly Lau Maria I. Zavodszky Olivia McKissick Nicole Mastrangelo Jessica Dion Bin Wang Daniel Ferretti David Koske Sydney Lehman Kathryn Koszka Helen McLaughlin Mei Liu Eric Marshall Attila J. Fabian Patrick Cul Source Type: research
Correction: Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models
Gene Therapy, Published online: 28 November 2022; doi:10.1038/s41434-022-00377-8Correction: Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models (Source: Gene Therapy)
Source: Gene Therapy - November 28, 2022 Category: Genetics & Stem Cells Authors: Ellie M. Chilcott Evalyne W. Muiruri Theodore C. Hirst Rafael J. Y áñez-Muñoz Source Type: research
Correction: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
Gene Therapy, Published online: 22 November 2022; doi:10.1038/s41434-022-00373-yCorrection: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application (Source: Gene Therapy)
Source: Gene Therapy - November 22, 2022 Category: Genetics & Stem Cells Authors: Lea Isabell Schwarze Dawid G łów Tanja Sonntag Almut Uhde Boris Fehse Source Type: research
Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice
Gene Therapy, Published online: 14 November 2022; doi:10.1038/s41434-022-00371-0Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice (Source: Gene Therapy)
Source: Gene Therapy - November 14, 2022 Category: Genetics & Stem Cells Authors: Maria Chen Boram Kim Maria I. Jarvis Samantha Fleury Shuyun Deng Shirin Nouraein Susan Butler Sangsin Lee Courtney Chambers H. Courtney Hodges Jerzy O. Szablowski Junghae Suh Omid Veiseh Source Type: research
Taylor Dispersion Analysis to support lipid-nanoparticle formulations for mRNA vaccines
Gene Therapy, Published online: 01 November 2022; doi:10.1038/s41434-022-00370-1Taylor Dispersion Analysis to support lipid-nanoparticle formulations for mRNA vaccines (Source: Gene Therapy)
Source: Gene Therapy - November 1, 2022 Category: Genetics & Stem Cells Authors: Camille Malburet Laurent Leclercq Jean-Fran çois Cotte J érôme Thiebaud Emilie Bazin Marie Garinot Herv é Cottet Source Type: research
A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification
Gene Therapy, Published online: 01 November 2022; doi:10.1038/s41434-022-00372-zA new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification (Source: Gene Therapy)
Source: Gene Therapy - November 1, 2022 Category: Genetics & Stem Cells Authors: Miguel M. Lopes Jacques Paysan Jos é Rino Sara M. Lopes Lu ís Pereira de Almeida Lu ísa Cortes Rui Jorge Nobre Source Type: research
Serotype-specific transduction of canine joint tissue explants and cultured monolayers by self-complementary adeno-associated viral vectors
Gene Therapy, Published online: 20 October 2022; doi:10.1038/s41434-022-00366-xSerotype-specific transduction of canine joint tissue explants and cultured monolayers by self-complementary adeno-associated viral vectors (Source: Gene Therapy)
Source: Gene Therapy - October 20, 2022 Category: Genetics & Stem Cells Authors: Ah Young Kim Felix Michael Duerr Jennifer N. Phillips Richard Jude Samulski Joshua C. Grieger Laurie R. Goodrich Source Type: research
Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction
Gene Therapy, Published online: 19 October 2022; doi:10.1038/s41434-022-00369-8Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction (Source: Gene Therapy)
Source: Gene Therapy - October 19, 2022 Category: Genetics & Stem Cells Authors: Gourish Mondal Caitlin J. VanLith Clara T. Nicolas Whitney S. Thompson William S. Cao Lori Hillin Benjamin J. Haugo Daniel R. O ’ Brien Jean-Pierre Kocher Robert A. Kaiser Joseph B. Lillegard Source Type: research
IgG-cleavage protein allows therapeutic AAV gene delivery in passively immunized MPS IIIA mice
Gene Therapy, Published online: 17 October 2022; doi:10.1038/s41434-022-00368-9IgG-cleavage protein allows therapeutic AAV gene delivery in passively immunized MPS IIIA mice (Source: Gene Therapy)
Source: Gene Therapy - October 17, 2022 Category: Genetics & Stem Cells Authors: Tierra A. Bobo Preston N. Samowitz Michael I. Robinson Laura I. Montes Lawrence J. Forsberg Richard Feng Nathan I. Nicely Haiyan Fu Source Type: research
Influence of donor age and comorbidities on transduced human adipose-derived stem cell in vitro osteogenic potential
Gene Therapy, Published online: 11 October 2022; doi:10.1038/s41434-022-00367-wInfluence of donor age and comorbidities on transduced human adipose-derived stem cell in vitro osteogenic potential (Source: Gene Therapy)
Source: Gene Therapy - October 11, 2022 Category: Genetics & Stem Cells Authors: Kevin Collon Jennifer A. Bell Matthew C. Gallo Stephanie W. Chang Sofia Bougioukli Osamu Sugiyama Jade Tassey Roger Hollis Nathanael Heckmann Daniel A. Oakes Donald B. Longjohn Denis Evseenko Donald B. Kohn Jay R. Lieberman Source Type: research
Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia
Gene Therapy, Published online: 02 October 2022; doi:10.1038/s41434-022-00364-zSurvey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia (Source: Gene Therapy)
Source: Gene Therapy - October 2, 2022 Category: Genetics & Stem Cells Authors: Heather G. Mack Alexis Ceecee Britten-Jones Myra B. McGuinness Fred K. Chen John R. Grigg Robyn V. Jamieson Thomas L. Edwards John De Roach Fleur O ’Hare Keith R. Martin Lauren N. Ayton Source Type: research
Characterization of a novel Pde6b-deficient rat model of retinal degeneration and treatment with adeno-associated virus (AAV) gene therapy
Gene Therapy, Published online: 29 September 2022; doi:10.1038/s41434-022-00365-yCharacterization of a novel Pde6b-deficient rat model of retinal degeneration and treatment with adeno-associated virus (AAV) gene therapy (Source: Gene Therapy)
Source: Gene Therapy - September 29, 2022 Category: Genetics & Stem Cells Authors: Ian C. Han Luke A. Wiley Dalyz Ochoa Mallory J. Lang Brynnon E. Harman Katie M. Sheehan Robert F. Mullins Edwin M. Stone Budd A. Tucker Source Type: research
Design, construction and in vivo functional assessment of a hinge truncated sFLT01
Gene Therapy, Published online: 16 September 2022; doi:10.1038/s41434-022-00362-1Design, construction and in vivo functional assessment of a hinge truncated sFLT01 (Source: Gene Therapy)
Source: Gene Therapy - September 16, 2022 Category: Genetics & Stem Cells Authors: Fahimeh Zakeri Hamid Latifi-Navid Zahra-Soheila Soheili Mehdi Sadeghi Seyed Shahriar Arab Shahram Samiei Ehsan Ranaei Pirmardan Sepideh Taghizadeh Hamid Ahmadieh Ali Hafezi-Moghadam Source Type: research
Changing trends in the development of AAV-based gene therapies: a meta-analysis of past and present therapies
Gene Therapy, Published online: 12 September 2022; doi:10.1038/s41434-022-00363-0Changing trends in the development of AAV-based gene therapies: a meta-analysis of past and present therapies (Source: Gene Therapy)
Source: Gene Therapy - September 12, 2022 Category: Genetics & Stem Cells Authors: Tamara Burdett Samir Nuseibeh Source Type: research
