Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
Gene Therapy, Published online: 19 April 2021; doi:10.1038/s41434-021-00259-5Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients (Source: Gene Therapy)
Source: Gene Therapy - April 19, 2021 Category: Genetics & Stem Cells Authors: Lea Isabell Schwarze Tanja Sonntag Stefan Wild Sabrina Schmitz Almut Uhde Boris Fehse Source Type: research
CARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma
Gene Therapy, Published online: 13 April 2021; doi:10.1038/s41434-021-00254-wCARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma (Source: Gene Therapy)
Source: Gene Therapy - April 13, 2021 Category: Genetics & Stem Cells Authors: Sabrina Prommersberger Michael Reiser Julia Beckmann Sophia Danhof Maximilian Amberger Patricia Quade-Lyssy Hermann Einsele Michael Hudecek Halvard Bonig Zolt án Ivics Source Type: research
Reviewer recognition
Gene Therapy, Published online: 26 March 2021; doi:10.1038/s41434-021-00253-xWe would like to thank all those listed below for taking the time to review for Gene Therapy in 2020—your generosity is much appreciated and we hope your association with the journal continues in the future. (Source: Gene Therapy)
Source: Gene Therapy - March 26, 2021 Category: Genetics & Stem Cells Source Type: research
Correction: Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions
Gene Therapy, Published online: 26 March 2021; doi:10.1038/s41434-021-00252-yCorrection: Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions (Source: Gene Therapy)
Source: Gene Therapy - March 26, 2021 Category: Genetics & Stem Cells Authors: Jalish M. Riyad Thomas Weber Source Type: research
Retroviral gene therapy in Germany with a view on previous experience and future perspectives
Gene Therapy, Published online: 22 March 2021; doi:10.1038/s41434-021-00237-xRetroviral gene therapy in Germany with a view on previous experience and future perspectives (Source: Gene Therapy)
Source: Gene Therapy - March 22, 2021 Category: Genetics & Stem Cells Authors: Michael A. Morgan Melanie Galla Manuel Grez Boris Fehse Axel Schambach Source Type: research
Current status and perspective of CAR-T and CAR-NK cell therapy trials in Germany
Gene Therapy, Published online: 22 March 2021; doi:10.1038/s41434-021-00246-wCurrent status and perspective of CAR-T and CAR-NK cell therapy trials in Germany (Source: Gene Therapy)
Source: Gene Therapy - March 22, 2021 Category: Genetics & Stem Cells Authors: Nawid Albinger Jessica Hartmann Evelyn Ullrich Source Type: research
Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9
Gene Therapy, Published online: 22 March 2021; doi:10.1038/s41434-021-00244-yEnhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9 (Source: Gene Therapy)
Source: Gene Therapy - March 22, 2021 Category: Genetics & Stem Cells Authors: Diptaman Chatterjee David J. Marmion Jodi L. McBride Fredric P. Manfredsson David Butler Anne Messer Jeffrey H. Kordower Source Type: research
Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair
Gene Therapy, Published online: 12 March 2021; doi:10.1038/s41434-021-00251-zCorrection of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair (Source: Gene Therapy)
Source: Gene Therapy - March 12, 2021 Category: Genetics & Stem Cells Authors: Colin L. Sweeney Mara Pavel-Dinu Uimook Choi Julie Brault Taylor Liu Sherry Koontz Linhong Li Narda Theobald Janet Lee Ezekiel A. Bello Xiaolin Wu Ronald J. Meis Gary A. Dahl Matthew H. Porteus Harry L. Malech Suk See De Ravin Source Type: research
Finding my why
Gene Therapy, Published online: 12 March 2021; doi:10.1038/s41434-021-00242-0Finding my why (Source: Gene Therapy)
Source: Gene Therapy - March 12, 2021 Category: Genetics & Stem Cells Authors: Samantha Barichievy Source Type: research
Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats
Gene Therapy, Published online: 11 March 2021; doi:10.1038/s41434-021-00249-7Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats (Source: Gene Therapy)
Source: Gene Therapy - March 11, 2021 Category: Genetics & Stem Cells Authors: Goichi Beck Jie Zhang Kayoko Fong Hideki Mochizuki M. Maral Mouradian Stella M. Papa Source Type: research
AAV9-mediated Schwann cell-targeted gene therapy rescues a model of demyelinating neuropathy
Gene Therapy, Published online: 10 March 2021; doi:10.1038/s41434-021-00250-0AAV9-mediated Schwann cell-targeted gene therapy rescues a model of demyelinating neuropathy (Source: Gene Therapy)
Source: Gene Therapy - March 10, 2021 Category: Genetics & Stem Cells Authors: Alexia Kagiava Christos Karaiskos Jan Richter Christina Tryfonos Matthew J. Jennings Amanda J. Heslegrave Irene Sargiannidou Marina Stavrou Henrik Zetterberg Mary M. Reilly Christina Christodoulou Rita Horvath Kleopas A. Kleopa Source Type: research
Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells
Gene Therapy, Published online: 10 March 2021; doi:10.1038/s41434-021-00239-9Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells (Source: Gene Therapy)
Source: Gene Therapy - March 10, 2021 Category: Genetics & Stem Cells Authors: Anna K. Dreismann Michelle E. McClements Alun R. Barnard Elise Orhan Jane P. Hughes Peter J. Lachmann Robert E. MacLaren Source Type: research
Genome editing using CRISPR/Cas9 to treat hereditary hematological disorders
Gene Therapy, Published online: 09 March 2021; doi:10.1038/s41434-021-00247-9Genome editing using CRISPR/Cas9 to treat hereditary hematological disorders (Source: Gene Therapy)
Source: Gene Therapy - March 9, 2021 Category: Genetics & Stem Cells Authors: Yan Chen Ruiting Wen Zhigang Yang Zhanghui Chen Source Type: research
Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation
Gene Therapy, Published online: 08 March 2021; doi:10.1038/s41434-021-00248-8Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation (Source: Gene Therapy)
Source: Gene Therapy - March 8, 2021 Category: Genetics & Stem Cells Authors: Gileade P. Freitas Helena B. Lopes Alann T. P. Souza Maria Paula O. Gomes Georgia K. Quiles Jonathan Gordon Coralee Tye Janet L. Stein Gary S. Stein Jane B. Lian Marcio M. Beloti Adalberto L. Rosa Source Type: research
Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active
Gene Therapy, Published online: 04 March 2021; doi:10.1038/s41434-021-00235-zAlternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active (Source: Gene Therapy)
Source: Gene Therapy - March 4, 2021 Category: Genetics & Stem Cells Authors: Luca Giordano Manish K. Aneja Natascha Sommer Nasim Alebrahimdehkordi Alireza Seraji Norbert Weissmann Carsten Rudolph Christian Plank Howard T. Jacobs Marten Szibor Source Type: research
