rAAV-based and intraprostatically delivered miR-34a therapeutics for efficient inhibition of prostate cancer progression
Gene Therapy, Published online: 06 July 2021; doi:10.1038/s41434-021-00275-5rAAV-based and intraprostatically delivered miR-34a therapeutics for efficient inhibition of prostate cancer progression (Source: Gene Therapy)
Source: Gene Therapy - July 6, 2021 Category: Genetics & Stem Cells Authors: Jianzhong Ai Jia Li Qin Su Hong Ma Ran He Qiang Wei Hong Li Guangping Gao Source Type: research

Novel tool to quantify with single-cell resolution the number of incoming AAV genomes co-expressed in the mouse nervous system
Gene Therapy, Published online: 28 June 2021; doi:10.1038/s41434-021-00272-8Novel tool to quantify with single-cell resolution the number of incoming AAV genomes co-expressed in the mouse nervous system (Source: Gene Therapy)
Source: Gene Therapy - June 28, 2021 Category: Genetics & Stem Cells Authors: Carola J. Maturana Jessica L. Verpeut Mahdi Kooshkbaghi Esteban A. Engel Source Type: research

Stem cell-based therapy for hirschsprung disease, do we have the guts to treat?
Gene Therapy, Published online: 14 June 2021; doi:10.1038/s41434-021-00268-4Stem cell-based therapy for hirschsprung disease, do we have the guts to treat? (Source: Gene Therapy)
Source: Gene Therapy - June 14, 2021 Category: Genetics & Stem Cells Authors: Ali Fouad Alhawaj Source Type: research

Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
Gene Therapy, Published online: 11 June 2021; doi:10.1038/s41434-021-00271-9Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application (Source: Gene Therapy)
Source: Gene Therapy - June 11, 2021 Category: Genetics & Stem Cells Authors: Lea Isabell Schwarze Dawid G łów Tanja Sonntag Almut Uhde Boris Fehse Source Type: research

The Gibco™ CTS™ Rotea™ system story—a case study of industry-academia collaboration
Gene Therapy, Published online: 10 June 2021; doi:10.1038/s41434-021-00266-6The Gibco™ CTS™ Rotea™ system story—a case study of industry-academia collaboration (Source: Gene Therapy)
Source: Gene Therapy - June 10, 2021 Category: Genetics & Stem Cells Authors: Anqi Li David James Rebecca Lim Source Type: research

Adjuvant properties of IFN-γ and GM-CSF in the scFv6.C4 DNA vaccine against CEA-expressing tumors
Gene Therapy, Published online: 09 June 2021; doi:10.1038/s41434-021-00270-wAdjuvant properties of IFN-γ and GM-CSF in the scFv6.C4 DNA vaccine against CEA-expressing tumors (Source: Gene Therapy)
Source: Gene Therapy - June 9, 2021 Category: Genetics & Stem Cells Authors: Bianca Ferrarini Zanetti Camila Pontes Ferreira Jos é Ronnie Carvalho Vasconcelos Sang Won Han Source Type: research

Chitosan-coated Zn-metal-organic framework nanocomposites for effective targeted delivery of LNA-antisense miR-224 to colon tumor: in vitro studies
Gene Therapy, Published online: 09 June 2021; doi:10.1038/s41434-021-00265-7Chitosan-coated Zn-metal-organic framework nanocomposites for effective targeted delivery of LNA-antisense miR-224 to colon tumor: in vitro studies (Source: Gene Therapy)
Source: Gene Therapy - June 9, 2021 Category: Genetics & Stem Cells Authors: Negin Mokri Zahra Sepehri Farnaz Faninam Sepideh Khaleghi Negar Motakef Kazemi Mehrdad Hashemi Source Type: research

Control of gene doping in human and horse sports
Gene Therapy, Published online: 07 June 2021; doi:10.1038/s41434-021-00267-5Control of gene doping in human and horse sports (Source: Gene Therapy)
Source: Gene Therapy - June 7, 2021 Category: Genetics & Stem Cells Authors: Teruaki Tozaki Natasha A. Hamilton Source Type: research

Schwann cell gene therapies in sight
Gene Therapy, Published online: 07 June 2021; doi:10.1038/s41434-021-00264-8Schwann cell gene therapies in sight (Source: Gene Therapy)
Source: Gene Therapy - June 7, 2021 Category: Genetics & Stem Cells Authors: Stephan Z üchner Source Type: research

The transformative potential of HSC gene therapy as a genetic medicine
Gene Therapy, Published online: 26 May 2021; doi:10.1038/s41434-021-00261-xThe transformative potential of HSC gene therapy as a genetic medicine (Source: Gene Therapy)
Source: Gene Therapy - May 26, 2021 Category: Genetics & Stem Cells Authors: Pervinder Sagoo H. Bobby Gaspar Source Type: research

Prime editing – an update on the field
Gene Therapy, Published online: 24 May 2021; doi:10.1038/s41434-021-00263-9Prime editing – an update on the field (Source: Gene Therapy)
Source: Gene Therapy - May 24, 2021 Category: Genetics & Stem Cells Authors: Janine Scholefield Patrick T. Harrison Source Type: research

RNAi and chemogenetic reporter co-regulation in primate striatal interneurons
Gene Therapy, Published online: 19 May 2021; doi:10.1038/s41434-021-00260-yRNAi and chemogenetic reporter co-regulation in primate striatal interneurons (Source: Gene Therapy)
Source: Gene Therapy - May 19, 2021 Category: Genetics & Stem Cells Authors: Walter Lerchner Abdullah A. Adil Sekinat Mumuney Wenliang Wang Rossella Falcone Janita Turchi Barry J. Richmond Source Type: research

Advantages of robotic assistance over a manual approach in simulated subretinal injections and its relevance for gene therapy
Gene Therapy, Published online: 17 May 2021; doi:10.1038/s41434-021-00262-wAdvantages of robotic assistance over a manual approach in simulated subretinal injections and its relevance for gene therapy (Source: Gene Therapy)
Source: Gene Therapy - May 17, 2021 Category: Genetics & Stem Cells Authors: Reza Ladha Thijs Meenink Jorrit Smit Marc D. de Smet Source Type: research

Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors
Gene Therapy, Published online: 06 May 2021; doi:10.1038/s41434-021-00255-9Membrane-bound MMP-14 protease-activatable adeno-associated viral vectors for gene delivery to pancreatic tumors (Source: Gene Therapy)
Source: Gene Therapy - May 6, 2021 Category: Genetics & Stem Cells Authors: Susan S. Butler Kenjiro Date Takashi Okumura Cooper Lueck Bidyut Ghosh Anirban Maitra Junghae Suh Source Type: research

Distinct functions of CAR-T cells possessing a dectin-1 intracellular signaling domain
Gene Therapy, Published online: 06 May 2021; doi:10.1038/s41434-021-00257-7Distinct functions of CAR-T cells possessing a dectin-1 intracellular signaling domain (Source: Gene Therapy)
Source: Gene Therapy - May 6, 2021 Category: Genetics & Stem Cells Authors: Xiao Liang Yong Huang Dan Li Xiao Yang Lin Jiang Weilin Zhou Jinhua Su Nianyong Chen Wei Wang Source Type: research