Long-term Follow-up and Safety of Patients after an Upfront Therapy with Letrozole for Early Breast Cancer in Routine Clinical Care - The PreFace Study
CONCLUSIONS: The risk profile of postmenopausal BC patients selected for a five-year upfront letrozole therapy showed a moderate recurrence and death risk. However, in subgroups with unfavorable risk factors, prognosis warrants an improvement, which might be achieved with novel targeted therapies.PMID:38344045 | PMC:PMC10853028 | DOI:10.1055/a-2238-3153 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Carolin C Hack Nicolai Maass Bahriye Aktas Sherko K ümmel Christoph Thomssen Christopher Wolf Hans-Christian Kolberg Cosima Brucker Wolfgang Janni Peter Dall Andreas Schneeweiss Frederik Marme Matthias Ruebner Anna-Katharin Theuser Nadine M Hofmann Sybil Source Type: research
Treatment in Certified Breast Cancer Centers Improves Chances of Survival of Patients with Breast Cancer: Evidence Based on Health Care Data from the WiZen Study
CONCLUSIONS: Patients who are treated by an interdisciplinary team in a DKG-certified breast cancer had clear and statistically significantly better survival rates. Certification is therefore an effective means of improving the quality of care, and more patients should be treated in certified breast cancer centers.PMID:38344046 | PMC:PMC10853029 | DOI:10.1055/a-1869-1772 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Olaf Schoffer Pauline Wimberger Michael Gerken Veronika Bierbaum Christoph Bobeth Martin R ößler Patrik Dr öge Thomas Ruhnke Christian G ünster Kees Kleihues-van Tol Theresa Link Anton Scharl Elisabeth C Inwald Karin Kast Thomas Papathemelis Olaf Ortm Source Type: research
Identification of Patients with Early HR+ HER2- Breast Cancer at High Risk of Recurrence
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):164-184. doi: 10.1055/a-2238-3199. eCollection 2024 Feb.ABSTRACTBreast cancer incidence has increased in the last two decades and, simultaneously, survival has improved due to earlier detection and improved treatment options. Despite this improvement, locoregional recurrences and distant metastases occur in up to 10 and 30% of women diagnosed with early breast cancer, respectively. Around 70% of breast cancers are hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), and associated with a persistent risk of relapse up to 20 years after diagno...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Peter A Fasching Hans Kreipe Lucia Del Mastro Eva Ciruelos Gilles Freyer Agnieszka Korfel Nadia Chouaki Clemens Stoffregen Francisco Sapunar David Cameron Source Type: research
Nausea and Vomiting of Pregnancy and its Management with the Dual-Release Formulation of Doxylamine and Pyridoxine
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):144-152. doi: 10.1055/a-2225-5883. eCollection 2024 Feb.ABSTRACTNausea and vomiting of pregnancy (NVP) is among the most common conditions that pregnant women encounter in the early stages of pregnancy. It can affect up to 85% of pregnant women, thus representing a significant public health concern. NVP results in substantial negative physical, emotional, and financial consequences. Despite its prevalence, the pathogenesis remains elusive. Few guidelines have been published; however, several interventions exist for the symptomatic treatment of NVP. The aim of this review is to pr...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Ekkehard Schleu ßner Susan J äkel Christoph Keck Kirsten Kuhlmann Mandy Mangler Wolfgang E Paulus Johanna Eiblwieser Theresa Steeb Pedro-Antonio Regidor Source Type: research
Management of Rheumatic Diseases During Pregnancy and Breastfeeding: Position Paper of the Working Group for Obstetrics and Prenatal Medicine in the German Society for Gynecology and Obstetrics e. V. (AGG - Section Maternal Diseases in Pregnancy)
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):130-143. doi: 10.1055/a-2201-2680. eCollection 2024 Feb.ABSTRACTPurpose These recommendations issued by the AGG (Section Maternal Diseases in Pregnancy) were developed as a rapid orientation on maternal rheumatic diseases for counselling and disease management in pregnancy and breastfeeding. Methods The standard literature, consensus and position papers, guidelines and recommendations by other specialist associations were evaluated by a task force of the Section and summarized in these recommendations following a joint consensus process. Recommendations This paper provides an ori...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Bettina Kuschel Ute Margaretha Sch äfer-Graf Markus Schmidt Maritta K ühnert Carsten Hagenbeck Klaus Th ürmel AGG – Section Maternal Diseases in Pregnancy Source Type: research
Long-term Follow-up and Safety of Patients after an Upfront Therapy with Letrozole for Early Breast Cancer in Routine Clinical Care - The PreFace Study
CONCLUSIONS: The risk profile of postmenopausal BC patients selected for a five-year upfront letrozole therapy showed a moderate recurrence and death risk. However, in subgroups with unfavorable risk factors, prognosis warrants an improvement, which might be achieved with novel targeted therapies.PMID:38344045 | PMC:PMC10853028 | DOI:10.1055/a-2238-3153 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Carolin C Hack Nicolai Maass Bahriye Aktas Sherko K ümmel Christoph Thomssen Christopher Wolf Hans-Christian Kolberg Cosima Brucker Wolfgang Janni Peter Dall Andreas Schneeweiss Frederik Marme Matthias Ruebner Anna-Katharin Theuser Nadine M Hofmann Sybil Source Type: research
Treatment in Certified Breast Cancer Centers Improves Chances of Survival of Patients with Breast Cancer: Evidence Based on Health Care Data from the WiZen Study
CONCLUSIONS: Patients who are treated by an interdisciplinary team in a DKG-certified breast cancer had clear and statistically significantly better survival rates. Certification is therefore an effective means of improving the quality of care, and more patients should be treated in certified breast cancer centers.PMID:38344046 | PMC:PMC10853029 | DOI:10.1055/a-1869-1772 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Olaf Schoffer Pauline Wimberger Michael Gerken Veronika Bierbaum Christoph Bobeth Martin R ößler Patrik Dr öge Thomas Ruhnke Christian G ünster Kees Kleihues-van Tol Theresa Link Anton Scharl Elisabeth C Inwald Karin Kast Thomas Papathemelis Olaf Ortm Source Type: research
Identification of Patients with Early HR+ HER2- Breast Cancer at High Risk of Recurrence
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):164-184. doi: 10.1055/a-2238-3199. eCollection 2024 Feb.ABSTRACTBreast cancer incidence has increased in the last two decades and, simultaneously, survival has improved due to earlier detection and improved treatment options. Despite this improvement, locoregional recurrences and distant metastases occur in up to 10 and 30% of women diagnosed with early breast cancer, respectively. Around 70% of breast cancers are hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), and associated with a persistent risk of relapse up to 20 years after diagno...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Peter A Fasching Hans Kreipe Lucia Del Mastro Eva Ciruelos Gilles Freyer Agnieszka Korfel Nadia Chouaki Clemens Stoffregen Francisco Sapunar David Cameron Source Type: research
Nausea and Vomiting of Pregnancy and its Management with the Dual-Release Formulation of Doxylamine and Pyridoxine
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):144-152. doi: 10.1055/a-2225-5883. eCollection 2024 Feb.ABSTRACTNausea and vomiting of pregnancy (NVP) is among the most common conditions that pregnant women encounter in the early stages of pregnancy. It can affect up to 85% of pregnant women, thus representing a significant public health concern. NVP results in substantial negative physical, emotional, and financial consequences. Despite its prevalence, the pathogenesis remains elusive. Few guidelines have been published; however, several interventions exist for the symptomatic treatment of NVP. The aim of this review is to pr...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Ekkehard Schleu ßner Susan J äkel Christoph Keck Kirsten Kuhlmann Mandy Mangler Wolfgang E Paulus Johanna Eiblwieser Theresa Steeb Pedro-Antonio Regidor Source Type: research
Management of Rheumatic Diseases During Pregnancy and Breastfeeding: Position Paper of the Working Group for Obstetrics and Prenatal Medicine in the German Society for Gynecology and Obstetrics e. V. (AGG - Section Maternal Diseases in Pregnancy)
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):130-143. doi: 10.1055/a-2201-2680. eCollection 2024 Feb.ABSTRACTPurpose These recommendations issued by the AGG (Section Maternal Diseases in Pregnancy) were developed as a rapid orientation on maternal rheumatic diseases for counselling and disease management in pregnancy and breastfeeding. Methods The standard literature, consensus and position papers, guidelines and recommendations by other specialist associations were evaluated by a task force of the Section and summarized in these recommendations following a joint consensus process. Recommendations This paper provides an ori...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Bettina Kuschel Ute Margaretha Sch äfer-Graf Markus Schmidt Maritta K ühnert Carsten Hagenbeck Klaus Th ürmel AGG – Section Maternal Diseases in Pregnancy Source Type: research
Long-term Follow-up and Safety of Patients after an Upfront Therapy with Letrozole for Early Breast Cancer in Routine Clinical Care - The PreFace Study
CONCLUSIONS: The risk profile of postmenopausal BC patients selected for a five-year upfront letrozole therapy showed a moderate recurrence and death risk. However, in subgroups with unfavorable risk factors, prognosis warrants an improvement, which might be achieved with novel targeted therapies.PMID:38344045 | PMC:PMC10853028 | DOI:10.1055/a-2238-3153 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Carolin C Hack Nicolai Maass Bahriye Aktas Sherko K ümmel Christoph Thomssen Christopher Wolf Hans-Christian Kolberg Cosima Brucker Wolfgang Janni Peter Dall Andreas Schneeweiss Frederik Marme Matthias Ruebner Anna-Katharin Theuser Nadine M Hofmann Sybil Source Type: research
Treatment in Certified Breast Cancer Centers Improves Chances of Survival of Patients with Breast Cancer: Evidence Based on Health Care Data from the WiZen Study
CONCLUSIONS: Patients who are treated by an interdisciplinary team in a DKG-certified breast cancer had clear and statistically significantly better survival rates. Certification is therefore an effective means of improving the quality of care, and more patients should be treated in certified breast cancer centers.PMID:38344046 | PMC:PMC10853029 | DOI:10.1055/a-1869-1772 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Olaf Schoffer Pauline Wimberger Michael Gerken Veronika Bierbaum Christoph Bobeth Martin R ößler Patrik Dr öge Thomas Ruhnke Christian G ünster Kees Kleihues-van Tol Theresa Link Anton Scharl Elisabeth C Inwald Karin Kast Thomas Papathemelis Olaf Ortm Source Type: research
Identification of Patients with Early HR+ HER2- Breast Cancer at High Risk of Recurrence
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):164-184. doi: 10.1055/a-2238-3199. eCollection 2024 Feb.ABSTRACTBreast cancer incidence has increased in the last two decades and, simultaneously, survival has improved due to earlier detection and improved treatment options. Despite this improvement, locoregional recurrences and distant metastases occur in up to 10 and 30% of women diagnosed with early breast cancer, respectively. Around 70% of breast cancers are hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), and associated with a persistent risk of relapse up to 20 years after diagno...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Peter A Fasching Hans Kreipe Lucia Del Mastro Eva Ciruelos Gilles Freyer Agnieszka Korfel Nadia Chouaki Clemens Stoffregen Francisco Sapunar David Cameron Source Type: research
Nausea and Vomiting of Pregnancy and its Management with the Dual-Release Formulation of Doxylamine and Pyridoxine
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):144-152. doi: 10.1055/a-2225-5883. eCollection 2024 Feb.ABSTRACTNausea and vomiting of pregnancy (NVP) is among the most common conditions that pregnant women encounter in the early stages of pregnancy. It can affect up to 85% of pregnant women, thus representing a significant public health concern. NVP results in substantial negative physical, emotional, and financial consequences. Despite its prevalence, the pathogenesis remains elusive. Few guidelines have been published; however, several interventions exist for the symptomatic treatment of NVP. The aim of this review is to pr...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Ekkehard Schleu ßner Susan J äkel Christoph Keck Kirsten Kuhlmann Mandy Mangler Wolfgang E Paulus Johanna Eiblwieser Theresa Steeb Pedro-Antonio Regidor Source Type: research
Management of Rheumatic Diseases During Pregnancy and Breastfeeding: Position Paper of the Working Group for Obstetrics and Prenatal Medicine in the German Society for Gynecology and Obstetrics e. V. (AGG - Section Maternal Diseases in Pregnancy)
Geburtshilfe Frauenheilkd. 2024 Feb 8;84(2):130-143. doi: 10.1055/a-2201-2680. eCollection 2024 Feb.ABSTRACTPurpose These recommendations issued by the AGG (Section Maternal Diseases in Pregnancy) were developed as a rapid orientation on maternal rheumatic diseases for counselling and disease management in pregnancy and breastfeeding. Methods The standard literature, consensus and position papers, guidelines and recommendations by other specialist associations were evaluated by a task force of the Section and summarized in these recommendations following a joint consensus process. Recommendations This paper provides an ori...
Source: Geburtshilfe und Frauenheilkunde - February 12, 2024 Category: OBGYN Authors: Bettina Kuschel Ute Margaretha Sch äfer-Graf Markus Schmidt Maritta K ühnert Carsten Hagenbeck Klaus Th ürmel AGG – Section Maternal Diseases in Pregnancy Source Type: research
