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Pharmacogenomic biomarkers in coronary artery disease: a narrative review
Biomark Med. 2024 Mar 8. doi: 10.2217/bmm-2023-0476. Online ahead of print.ABSTRACTCoronary artery disease (CAD) has a high mortality rate. Despite various therapeutic targets, non-responsiveness to drugs remains a prevalent issue. Pharmacogenomics assesses the way an individual's genetic attributes affect their likely response to drug therapy. Single-nucleotide polymorphisms play a crucial role in determining these outcomes. This review offers an overview of single-nucleotide polymorphisms investigated in clinical studies and their associations with drug response/nonresponse in the treatment of CAD. A total of 104 studies...
Source: Future Medicine: Biomarkers in Medicine - March 8, 2024 Category: Internal Medicine Authors: Pamila Dua Sandeep Seth Bhavana Prasher Mitali Mukerji Subir Kumar Maulik K H Reeta Source Type: research

Lipid accumulation product is a valid predictor of hepatic steatosis and nonalcoholic fatty liver disease
Conclusion: LAP is an ideal biomarker of hepatic steatosis and NAFLD.PMID:38456353 | DOI:10.2217/bmm-2023-0725 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 8, 2024 Category: Internal Medicine Authors: Qiaoli Huang Xuying Tan Qiongmei Wu Hanqing Zhao Hangjun Chen Xinxue Yu Jinting Wang Xueyi Huang Yurong Huang Jun Wei Feng Wu Huilian Zhu Lijun Wang Source Type: research

Diagnostic predictability of serum miR-4793-3p and miR-1180-3p expression in community-acquired pneumonia
Conclusion: Increased levels of miR-4793-3p and miR-1180-3p may indicate severe pneumonia development. Plasma miRNA profiling enables early prediction of severe CAP, aiding therapeutic decisions.PMID:38456294 | DOI:10.2217/bmm-2023-0463 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 8, 2024 Category: Internal Medicine Authors: Rong Chai Cihang Zhou Zhenli Hu Jingjing Hu Source Type: research

PLK4 reflects extrathyroidal invasion, high tumor stage and poor prognosis in papillary thyroid carcinoma patients
Conclusion: Tumor PLK4 reflects extrathyroidal invasion, higher tumor stage and shortened survival in PTC.PMID:38440866 | DOI:10.2217/bmm-2023-0565 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 5, 2024 Category: Internal Medicine Authors: Xiaonan Hu Jiawei Yu Mengshi Chen Rui Pang Source Type: research

Linkage of CDC42 and T-helper cell ratio with anxiety, depression and quality of life in ST-elevation myocardial infarction
Conclusion: CDC42 correlates with reduced Th1/Th2 and Th17/Treg ratios, reduced anxiety and depression, and improved quality of life in ST-elevation myocardial infarction patients undergoing percutaneous coronary intervention.PMID:38440868 | DOI:10.2217/bmm-2023-0712 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 5, 2024 Category: Internal Medicine Authors: Xuechao Wang Junjie Feng Shaohua Luan Yong Zhou Shipan Zhang Hongling Su Zhongyu Wang Source Type: research

C-reactive protein to albumin ratio may predict in-hospital mortality in non-ST elevation myocardial infarction
Conclusion: This study revealed that CAR is an inexpensive and significant factor in predicting in-hospital mortality in patients undergoing percutaneous coronary intervention for NSTEMI.PMID:38440872 | DOI:10.2217/bmm-2023-0682 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 5, 2024 Category: Internal Medicine Authors: Tu ğba S Menekşe İlker Kaçer Muhammet Hac ımustafaoğlu Murat G ül Can Ate ş Source Type: research

Study on red blood cell distribution width in children with severe < em > Mycoplasma pneumoniae < /em > pneumonia
Conclusion: This study revealed that RDW could be correlated with the long-term prognosis and severity of severe MPP.PMID:38440878 | DOI:10.2217/bmm-2023-0671 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - March 5, 2024 Category: Internal Medicine Authors: Lin Wu Jinyan Zhang Hui-Min Zhang Cheng-Yi Wang Source Type: research