Fungal microtubule organizing centers are evolutionarily unstable structures
In this study we find that loss of cilia corresponds to loss of evolutionary stability for fungal MTOCs. We used iterative search algorithms to identify proteins homologous to those found in saccharomyces cerevisiae, and schizosaccharomyces pombe MTOCs, and calculated site-specific rates of change for those proteins that were broadly phylogenetically distributed. Our results indicate that both the protein composition of MTOCs as well as the sequence of MTOC proteins are poorly conserved throughout the fungal kingdom. To begin to reconcile this rapid evolutionary change with the rigid structure and essential function of the...
Source: Fungal Genetics and Biology - March 14, 2024 Category: Biology Authors: Adam Grazzini Ann M Cavanaugh Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4;171:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-muta...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
Coordination of two regulators SscA and VosA in Aspergillus nidulans conidia
Fungal Genet Biol. 2024 Mar 4:103877. doi: 10.1016/j.fgb.2024.103877. Online ahead of print.ABSTRACTAirborne fungal spores are a major cause of fungal diseases in humans, animals, and plants as well as contamination of foods. Previous studies found a variety of regulators including VosA, VelB, WetA, and SscA for sporogenesis and the long-term viability in Aspergillus nidulans. To gain a mechanistic understanding of the complex regulatory mechanisms in asexual spores, here, we focused on the relationship between VosA and SscA using comparative transcriptomic analysis and phenotypic studies. The ΔsscA ΔvosA double-mutant c...
Source: Fungal Genetics and Biology - March 6, 2024 Category: Biology Authors: Ye-Eun Son Hee-Soo Park Source Type: research
The serine-threonine protein kinase Snf1 orchestrates the expression of plant cell wall-degrading enzymes and is required for full virulence of the maize pathogen Colletotrichum graminicola
In this study, we identified and functionally characterized the SNF1 homolog of C. graminicola. Δsnf1 mutants showed reduced vegetative growth and asexual sporulation rates on media containing polymeric carbon sources. Microscopy revealed reduced efficacies in appressorial penetration of cuticle and epidermal cell wall, and formation of unusual medusa-like biotrophic hyphae by Δsnf1 mutants. Severe and moderate virulence reductions were observed on intact and wounded leaves, respectively. Employing RNA-sequencing we show for the first time that more than 2,500 genes are directly or indirectly controlled by Snf1 in necrot...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Alan de Oliveira Silva Bennet Rohan Fernando Devasahayam Lala Aliyeva-Schnorr Chirlei Glienke Holger B Deising Source Type: research
The genus Acrophialophora: History, phylogeny, morphology, beneficial effects and pathogenicity
Fungal Genet Biol. 2024 Feb 15;171:103875. doi: 10.1016/j.fgb.2024.103875. Online ahead of print.ABSTRACTThe genus Acrophialophora is a thermotolerant fungus, which is widely distributed in temperate and tropical zones. This fungus is classified in Ascomycota and belongs to the Chaetomiaceae family and the genera of Parathielavia, Pseudothielavia and Hyalosphaerella are closely related to Acrophialophora. For this genus have been reported 28 species so far, which two species of Acrophialophora jodhpurensis and Acrophialophora teleoafricana produce only sexual phase and other species produce asexual form. Therefore, produci...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Zoha Daroodi Parissa Taheri Source Type: research
The serine-threonine protein kinase Snf1 orchestrates the expression of plant cell wall-degrading enzymes and is required for full virulence of the maize pathogen Colletotrichum graminicola
In this study, we identified and functionally characterized the SNF1 homolog of C. graminicola. Δsnf1 mutants showed reduced vegetative growth and asexual sporulation rates on media containing polymeric carbon sources. Microscopy revealed reduced efficacies in appressorial penetration of cuticle and epidermal cell wall, and formation of unusual medusa-like biotrophic hyphae by Δsnf1 mutants. Severe and moderate virulence reductions were observed on intact and wounded leaves, respectively. Employing RNA-sequencing we show for the first time that more than 2,500 genes are directly or indirectly controlled by Snf1 in necrot...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Alan de Oliveira Silva Bennet Rohan Fernando Devasahayam Lala Aliyeva-Schnorr Chirlei Glienke Holger B Deising Source Type: research
The genus Acrophialophora: History, phylogeny, morphology, beneficial effects and pathogenicity
Fungal Genet Biol. 2024 Feb 15;171:103875. doi: 10.1016/j.fgb.2024.103875. Online ahead of print.ABSTRACTThe genus Acrophialophora is a thermotolerant fungus, which is widely distributed in temperate and tropical zones. This fungus is classified in Ascomycota and belongs to the Chaetomiaceae family and the genera of Parathielavia, Pseudothielavia and Hyalosphaerella are closely related to Acrophialophora. For this genus have been reported 28 species so far, which two species of Acrophialophora jodhpurensis and Acrophialophora teleoafricana produce only sexual phase and other species produce asexual form. Therefore, produci...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Zoha Daroodi Parissa Taheri Source Type: research
The serine-threonine protein kinase Snf1 orchestrates the expression of plant cell wall-degrading enzymes and is required for full virulence of the maize pathogen Colletotrichum graminicola
In this study, we identified and functionally characterized the SNF1 homolog of C. graminicola. Δsnf1 mutants showed reduced vegetative growth and asexual sporulation rates on media containing polymeric carbon sources. Microscopy revealed reduced efficacies in appressorial penetration of cuticle and epidermal cell wall, and formation of unusual medusa-like biotrophic hyphae by Δsnf1 mutants. Severe and moderate virulence reductions were observed on intact and wounded leaves, respectively. Employing RNA-sequencing we show for the first time that more than 2,500 genes are directly or indirectly controlled by Snf1 in necrot...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Alan de Oliveira Silva Bennet Rohan Fernando Devasahayam Lala Aliyeva-Schnorr Chirlei Glienke Holger B Deising Source Type: research
The genus Acrophialophora: History, phylogeny, morphology, beneficial effects and pathogenicity
Fungal Genet Biol. 2024 Feb 15;171:103875. doi: 10.1016/j.fgb.2024.103875. Online ahead of print.ABSTRACTThe genus Acrophialophora is a thermotolerant fungus, which is widely distributed in temperate and tropical zones. This fungus is classified in Ascomycota and belongs to the Chaetomiaceae family and the genera of Parathielavia, Pseudothielavia and Hyalosphaerella are closely related to Acrophialophora. For this genus have been reported 28 species so far, which two species of Acrophialophora jodhpurensis and Acrophialophora teleoafricana produce only sexual phase and other species produce asexual form. Therefore, produci...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Zoha Daroodi Parissa Taheri Source Type: research
The serine-threonine protein kinase Snf1 orchestrates the expression of plant cell wall-degrading enzymes and is required for full virulence of the maize pathogen Colletotrichum graminicola
In this study, we identified and functionally characterized the SNF1 homolog of C. graminicola. Δsnf1 mutants showed reduced vegetative growth and asexual sporulation rates on media containing polymeric carbon sources. Microscopy revealed reduced efficacies in appressorial penetration of cuticle and epidermal cell wall, and formation of unusual medusa-like biotrophic hyphae by Δsnf1 mutants. Severe and moderate virulence reductions were observed on intact and wounded leaves, respectively. Employing RNA-sequencing we show for the first time that more than 2,500 genes are directly or indirectly controlled by Snf1 in necrot...
Source: Fungal Genetics and Biology - February 17, 2024 Category: Biology Authors: Alan de Oliveira Silva Bennet Rohan Fernando Devasahayam Lala Aliyeva-Schnorr Chirlei Glienke Holger B Deising Source Type: research
