Genome-wide survey and evolutionary history of the Pectin methylesterase (PME) gene family in the Dothideomycetes class of fungi
Fungal Genet Biol. 2023 Oct 3:103841. doi: 10.1016/j.fgb.2023.103841. Online ahead of print.ABSTRACTOnce deposited in the plant cell wall, pectin undergoes demethylesterification by endogenous pectin methylesterases (PMEs), which play various roles in growth and development, including defense against pathogen attacks. Pathogen PMEs can alter pectin's methylesterification pattern, increasing its susceptibility to degradation by other fungal pectinases and thus playing a critical role as virulence factors during early infection stages. To investigate the evolutionary history of PMEs in the Dothideomycetes class of fungi, we ...
Source: Fungal Genetics and Biology - October 5, 2023 Category: Biology Authors: Vinicius Delgado da Rocha Tha ís Carolina da Silva Dal'Sasso Maximiller Dal-Bianco Lamas Costa Luiz Orlando de Oliveira Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18;169:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory path...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory pathway ...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory pathway ...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory pathway ...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Fungal Genet Biol. 2023 Sep 18:103840. doi: 10.1016/j.fgb.2023.103840. Online ahead of print.ABSTRACTNeosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Golgi, from where they exit in clathrin-coated vesicles destined to the PM, directly or through endosomes. Post-Golgi membrane cargo trafficking also involves the cytoskeleton and the exocyst. The Golgi-dependent secretory pathway ...
Source: Fungal Genetics and Biology - September 20, 2023 Category: Biology Authors: Xenia Georgiou Sofia Dimou George Diallinas Martina Samiotaki Source Type: research
The histone demethylase KdmB is part of a trimeric protein complex and mediates virulence and mycotoxin production in Penicillium expansum
Fungal Genet Biol. 2023 Sep 16:103837. doi: 10.1016/j.fgb.2023.103837. Online ahead of print.ABSTRACTEpigenetic modification of chromosome structure has increasingly been associated with alterations in secondary metabolism and sporulation defects in filamentous fungal pathogens. Recently, the epigenetic reader protein SntB was shown to govern virulence, spore production and mycotoxin synthesis in the fruit pathogen Penicillium expansum. Through immunoprecipitation-coupled mass spectrometry, we found that SntB is a member of a protein complex with KdmB, a histone demethylase and the essential protein RpdA, a histone deacety...
Source: Fungal Genetics and Biology - September 18, 2023 Category: Biology Authors: Dianiris Luciano-Rosario Omer Barda Joanna Tannous Dean Frawley Özgür Bayram Dov Prusky Edward Sionov Nancy P Keller Source Type: research
The histone demethylase KdmB is part of a trimeric protein complex and mediates virulence and mycotoxin production in Penicillium expansum
Fungal Genet Biol. 2023 Sep 16:103837. doi: 10.1016/j.fgb.2023.103837. Online ahead of print.ABSTRACTEpigenetic modification of chromosome structure has increasingly been associated with alterations in secondary metabolism and sporulation defects in filamentous fungal pathogens. Recently, the epigenetic reader protein SntB was shown to govern virulence, spore production and mycotoxin synthesis in the fruit pathogen Penicillium expansum. Through immunoprecipitation-coupled mass spectrometry, we found that SntB is a member of a protein complex with KdmB, a histone demethylase and the essential protein RpdA, a histone deacety...
Source: Fungal Genetics and Biology - September 18, 2023 Category: Biology Authors: Dianiris Luciano-Rosario Omer Barda Joanna Tannous Dean Frawley Özgür Bayram Dov Prusky Edward Sionov Nancy P Keller Source Type: research
The histone demethylase KdmB is part of a trimeric protein complex and mediates virulence and mycotoxin production in Penicillium expansum
Fungal Genet Biol. 2023 Sep 16:103837. doi: 10.1016/j.fgb.2023.103837. Online ahead of print.ABSTRACTEpigenetic modification of chromosome structure has increasingly been associated with alterations in secondary metabolism and sporulation defects in filamentous fungal pathogens. Recently, the epigenetic reader protein SntB was shown to govern virulence, spore production and mycotoxin synthesis in the fruit pathogen Penicillium expansum. Through immunoprecipitation-coupled mass spectrometry, we found that SntB is a member of a protein complex with KdmB, a histone demethylase and the essential protein RpdA, a histone deacety...
Source: Fungal Genetics and Biology - September 18, 2023 Category: Biology Authors: Dianiris Luciano-Rosario Omer Barda Joanna Tannous Dean Frawley Özgür Bayram Dov Prusky Edward Sionov Nancy P Keller Source Type: research
