Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment
Publication date: Available online 28 December 2019Source: Fungal BiologyAuthor(s): Pooja Sethiya, Maruti Nandan Rai, Rikky Rai, Chirag Parsania, Kaeling Tan, Koon Ho WongAbstractThe ability to survive host-elicited oxidative stress is critical for microbial pathogens to cause infection. The human fungal pathogen Candida glabrata can tolerate high levels of oxidative stress and proliferate inside phagocytes. Previous studies had successfully identified a transcription response to oxidative stress including induction of a core set of detoxification genes. However, the findings only represent an early snapshot of a highly dy...
Source: Fungal Biology - December 29, 2019 Category: Biology Source Type: research
Editorial Board
Publication date: January 2020Source: Fungal Biology, Volume 124, Issue 1Author(s): (Source: Fungal Biology)
Source: Fungal Biology - December 29, 2019 Category: Biology Source Type: research
Colonization of Metarhizium anisopliae on the surface of pine tree logs: a promising biocontrol strategy for the Japanese pine sawyer, Monochamus alternatus
Publication date: Available online 26 December 2019Source: Fungal BiologyAuthor(s): Jong Cheol Kim, Sehyeon Baek, So Eun Park, Sihyeon Kim, Mi Rong Lee, Minsung Jo, Jae Seong Im, Panjung Ha, Jae Su Kim, Tae Young ShinAbstractWe investigated the colonization potential of five Metarhizium anisopliae isolates on pine tree surfaces under laboratory conditions, determined the influence of the pine bark extract on fungal growth and evaluated the insecticidal activity following colonization on the Japanese pine sawyer. Finally, the effect of colonization on adults pine sawyer was evaluated using the top three performing isolates ...
Source: Fungal Biology - December 27, 2019 Category: Biology Source Type: research
Phylogenetic re-evaluation of the Grosmannia penicillata complex (Ascomycota, Ophiostomatales), with the description of five new species from China and USA
Publication date: Available online 25 December 2019Source: Fungal BiologyAuthor(s): Mingliang Yin, Michael J. Wingfield, Xudong Zhou, Z. Wilhelm de BeerAbstractThe Grosmannia penicillata complex (Ophiostomatales, Ascomycota) is one of the major species complexes in Leptographium sensu lato. Most of these are wood staining fungi associated with conifer-infesting bark beetles, and the complex encompasses the type species of the genus Grosmannia. Yet the phylogenetic relationships of species within the complex is unresolved. The aim of this study was to re-evaluate the circumscriptions of all known species in the G. penicilla...
Source: Fungal Biology - December 26, 2019 Category: Biology Source Type: research
Multiple virus infections on Heterobasidion sp.
Publication date: Available online 23 December 2019Source: Fungal BiologyAuthor(s): Jarkko Hantula., Salla Mäkelä, Ping Xu, Veera Brusila, Heikki Nuorteva, Muhammad Kashif, Rafiqul Hyder, Eeva J. VainioAbstractHeterobasidion viruses have previously been shown to affect each other’s transmission and phenotypic effects on their hosts in a complex way. In this work, Heterobasidion parviporum strains hosting five coinfecting viruses simultaneously were constructed and used as donors in transmission experiments. They showed that viruses move more frequently between the mycelia of the same species than between the mycelia of...
Source: Fungal Biology - December 24, 2019 Category: Biology Source Type: research
Antifungal and anti-biofilm activity of designed derivatives from Kyotorphin
This study assessed the antimicrobial and antibiofilm activity of these peptides. The antifungal activity of kyotorphins was determined in representative strains of Candida species, including C. albicans ATCC 10231, C. krusei ATCC 6258, and six clinical isolates—C. dubliniensis 19-S, C. glabrata 217-S, C. lusitaniae 14-S, C. novergensis 51-S, C. parapsilosis 63, and C. tropicalis 140-S—obtained from the oral cavity of HIV-positive patients. The peptides were synthesized by standard solution or solid-phase synthesis, purified by RP-HPLC (purity>95%), and characterized by nuclear magnetic resonance. The results of the br...
Source: Fungal Biology - December 20, 2019 Category: Biology Source Type: research
The extraradical proteins of Rhizophagus irregularis: a shotgun proteomics approach
Publication date: Available online 10 December 2019Source: Fungal BiologyAuthor(s): Chelsea L. Murphy, Noha H. Youssef, Steve Hartson, Mostafa S. ElshahedAbstractArbuscular Mycorrhizal fungi (AMF, Glomeromycota) form obligate symbiotic associations with the roots of most terrestrial plants. Our understanding of the molecular mechanisms enabling AMF propagation and AMF-host interaction is currently incomplete. Analysis of AMF proteomes could yield important insights and generate hypotheses on the nature and mechanism of AMF-plant symbiosis. Here, we examined the extraradical mycelium proteomic profile of the arbuscular myco...
Source: Fungal Biology - December 11, 2019 Category: Biology Source Type: research
Differences in gene modulation in Saccharomyces cerevisiae indicate that maturity plays an important role in the high hydrostatic pressure stress response and resistance
Publication date: Available online 11 December 2019Source: Fungal BiologyAuthor(s): Brígida A.A. Spagnol, Tathiana F.S. Antunes, Oeber F. Quadros, A. Alberto R. Fernandes, Patricia M.B. FernandesAbstractThere is a strong relationship between the regulatory pathways to oxidative stress, longevity, and aging. High hydrostatic pressure (HHP) induces oxidative stress and activates cellular defense mechanisms. The understanding of these mechanisms is a strategy to delay damage associated with aging. Addressing resistance to stress and aging in Saccharomyces cerevisiae is a well-accepted approach since pathways involved in ener...
Source: Fungal Biology - December 11, 2019 Category: Biology Source Type: research
Potential use of machine learning methods in assessment of Fusarium culmorum and Fusarium proliferatum growth and mycotoxin production in treatments with antifungal agents
Publication date: Available online 22 November 2019Source: Fungal BiologyAuthor(s): Andrea Tarazona, Eva M. Mateo, José V. Gómez, David Romera, Fernando MateoAbstractFusarium-controlling fungicides are necessary to limit crop loss. Little is known about the effect of antifungal formulations at sub-lethal doses, and their interaction with abiotic factors, on Fusarium culmorum and F. proliferatum development and on zearalenone and fumonisin biosynthesis, respectively. In the present study different treatments based on sulfur, trifloxystrobin and demethylation inhibitor fungicides (cyproconazole, tebuconazole and prothioco...
Source: Fungal Biology - December 11, 2019 Category: Biology Source Type: research
Hydrosoluble phylloplane components of Theobroma cacao modulate the metabolism of Moniliophthora perniciosa spores during germination
Publication date: Available online 5 December 2019Source: Fungal BiologyAuthor(s): Joise Hander Mares, Karina Peres Gramacho, Juliano Oliveira Santana, Aurizângela Oliveira de Souza, Fátima Cerqueira Alvim, Carlos Priminho PirovaniAbstractThe surface of plants forms a defense barrier that directly inhibits the first point of contact of microorganisms with the host. To understand this defense mechanism in Moniliophthora perniciosa interaction with Theobroma cacao cv Catongo, the aim of this study was to compare the changes in protein expression in basidiospores of the fungus M. perniciosa in response the leaf water washes...
Source: Fungal Biology - December 5, 2019 Category: Biology Source Type: research
Quercetin-induced yeast apoptosis through mitochondrial dysfunction under the accumulation of magnesium in Candida albicans
Publication date: Available online 2 December 2019Source: Fungal BiologyAuthor(s): Min Seok Kwun, Dong Gun LeeAbstractLatterly, the upsurge in use of antifungal drugs has brought about the emergence of several drug-resistance strains, making it skeptical to continue relying on current therapeutic regime. In the necessity of resistance-free antifungal agent, flavonoids presented possibilities of replacing existing drugs, displaying antifungal activity against pathogenic fungi. Among them, quercetin, one of the most representative flavonoids, exhibited antifungal activity against Candida albicans. To inspect the further unde...
Source: Fungal Biology - December 2, 2019 Category: Biology Source Type: research
Transcriptomes of the interaction between Fusarium verticillioides and a Streptomyces strain reveal the fungal defense strategy under the pressure of a potential biocontrol agent
Publication date: Available online 27 November 2019Source: Fungal BiologyAuthor(s): C. Strub, C.A.T. Dieye, P.A. Nguyen, F. Constancias, N. Durand, S. Guendouz, M. Pratlong, A. Fontana, S. Schorr-GalindoAbstractThe actinobacteria Streptomyces sp. AV05 isolated from an organic amendment appears to be a potential biocontrol agent (BCA) against mycotoxigenic fungi. It was found to significantly inhibit Fusarium verticillioides growth and mycotoxin production during their co-cultivation on Petri dishes. F. verticillioides growth was durably affected while the decrease of the toxin production levels was reversible, suggesting d...
Source: Fungal Biology - November 28, 2019 Category: Biology Source Type: research
Potential use of machine learning methods in assessment of Fusarium culmorum and F. proliferatum growth and mycotoxin production in treatments with antifungal agents
Publication date: Available online 22 November 2019Source: Fungal BiologyAuthor(s): Andrea Tarazona, Eva M. Mateo, José V. Gómez, David Romera, Fernando MateoAbstractThe use of Fusarium-controlling fungicides is necessary to limit crop loss. Little is known about the effect of commercial antifungal formulations at sub-lethal doses, and their interaction with abiotic factors, on Fusarium culmorum and F. proliferatum development and on zearalenone and fumonisin biosynthesis, respectively. In the present study different treatments based on sulfur, trifloxystrobin and demethylation inhibitor fungicides (cyproconazole, tebuco...
Source: Fungal Biology - November 22, 2019 Category: Biology Source Type: research
Radioadapted Wangiella dermatitidis senses radiation in its environment in a melanin-dependent fashion
Publication date: Available online 12 November 2019Source: Fungal BiologyAuthor(s): Mackenzie E. Malo, Connor Frank, Ekaterina DadachovaAbstractBlack fungi withstand extreme stresses partly due to the presence of melanin. Melanin is associated with structural integrity and resistance to chemical and radiation stress. This results in improved health and fitness, specifically in extreme conditions. Our goal was to exploit the radiation sensing nature of melanized fungus in order to develop a radioadapted strain capable of responding to radiation in the environment. The protracted exposure of a melanized fungus, Wangiella de...
Source: Fungal Biology - November 21, 2019 Category: Biology Source Type: research
Extracellular peptidases of insect-associated fungi and their possible use in biological control programs and as pathogenicity markers
Publication date: Available online 20 November 2019Source: Fungal BiologyAuthor(s): Tatyana A. Semenova, Yakov E. Dunaevsky, Galina A. Beljakova, Mikhail A. BelozerskyAbstractThis review deals with characteristics of peptidases of fungi whose life cycles are associated with insects to varying degrees. The review examines the characteristic features of the extracellular peptidases of entomopathogenic fungi, the dependence of the specificity of these peptidases on the ecological characteristics of the fungi, and the role of peptidases in the development of the pathogenesis. Data on the properties and physiological role of hy...
Source: Fungal Biology - November 21, 2019 Category: Biology Source Type: research
