Acidosis in arterial blood gas testing is associated with clinical outcomes after endovascular thrombectomy
ConclusionAcidosis is associated with clinical outcomes after endovascular therapy and may help to select patients with poor prognosis in the acute early phase of recanalization. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Quality of life of children with residual seizures after epileptic resection surgery
ObjectiveEpilepsy dramatically affects the quality of life (QoL) of children, and resection surgery can improve their QoL by reducing seizures or completely controlling them. Children who have postoperative seizures tend to show a poorer QoL. The aim of the present study was to investigate the QoL of children with seizures after resection surgery and its influencing factors.MethodsIn the present study, we retrospectively reviewed 151 consecutive children who underwent resection surgery. We then divided them into two groups, seizure and seizure-free groups, according to the seizure outcomes 1 year after surgery. Variables w...
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Dynamic cognitive inhibition in the context of frustration: Increasing racial representation of adolescent athletes using mobile community-engaged EEG methods
DiscussionWe emphasize the urgent need to improve representation in cognitive neuroscience, particularly as it pertains to brain health. Importantly, we provide detailed guides to our methodological framework and practical suggestions to improve representative participation in studies utilizing high-density mobile EEG. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

The SFT2D2 gene is associated with the autoimmune pathology of schizophrenia in a Chinese population
This study is aimed to investigate schizophrenia-associated signals detected in the 1q24-25 region in order to identify a causal variant in LD with GWAS index SNPs, and the potential biological functions of the risk gene.MethodsRe-genotyping analysis was performed in the 1q24-25 region that harbors three GWAS index SNPs associated with schizophrenia (rs10489202, rs11586522, and rs6670165) in total of 9801 case-control subjects of Chinese Han origin. Circulating autoantibody levels were assessed using an in-house ELISA against a protein derived fragment encoded by SFT2D2 in total of 682 plasma samples.ResultsA rare variant ...
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Efficacy of interoceptive and embodied rehabilitative training protocol in patients with mild multiple sclerosis: A randomized controlled trial
This study suggests that enhancing interoceptive awareness could improve postural balance. Future studies with a larger sample of patients will be needed to better quantify the effects of an embodied rehabilitation. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Aberrant brain functional network strength related to cognitive impairment in age-related hearing loss
ConclusionThese findings enriched our understanding of the neural mechanisms underlying cognitive impairment associated with ARHL and may serve as a potential brain network biomarker for investigating and predicting cognitive difficulties. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Efficacy of portable sleep monitoring device in diagnosing central sleep apnea in patients with congestive heart failure
ConclusionPM devices could be used to identify instances of central sleep apnea among patients with HF. The results from PM were well-correlated with standard PSG results, and manual scoring was preferable to automated scoring. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 21, 2022 Category: Neurology Source Type: research

Sex differences in the progression of cerebral microbleeds in patients with concomitant cerebral small vessel disease
ConclusionThe progression of CMB over 2 years was significantly greater in women than in men. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Comparison of the efficacy of acupuncture-related Therapies for post-stroke motor aphasia: A Bayesian network meta-analysis
ConclusionThe NMA showed that STA combined with ST may be the best treatment to improve CER, compared with other combination treatments. However, since the overall quality and number of studies are limited, further RCTs with a large sample and multicenter are needed for further validation.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=316081, identifier CRD42022316081. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

The clinical significance of peripheral blood cell ratios in patients with intracranial aneurysm
ConclusionsWe demonstrated that lower PNR and PWR levels are associated with ruptured IA and a higher PHASES score. Unlike many other inflammatory markers and bioassays, peripheral blood cell ratios are inexpensive and readily available biomarkers that may be useful for risk stratification in patients with cerebral aneurysm. However, a long-term prospective study is needed to clarify this matter. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Acute flaccid myelitis a review of the literature
Acute flaccid myelitis (AFM) is a rare neurological disorder that first rose to national attention in 2014. This neurological disorder has a biennial presentation with every other even year being a peak year. Most patients present in childhood 5 days after a prodromal infection. Patients usually present with muscle weakness and hypo or areflexia in the summer or fall months. Clinical outcomes are variable however most patients do not improve. Currently there are no definitive prognostic factors or etiologies found. However, it is thought that enterovirus-D68 (EV-D68) could be a potential component in the pathobiology of AF...
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Endoscopic surgery for spontaneous supratentorial intracerebral haemorrhage: A systematic review and meta-analysis
ConclusionES showed significantly improved favourable functional outcome and mortality rates compared to BMT while showing reduced length of surgery and lower complication rates compared to CC. Therefore, ES appears a promising approach for treatment of SSICH justifying further prospective trials.Systematic review registrationPROSPERO, identifier: CRD42020181018. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Comprehensive profile and natural history of pediatric patients with spinal muscular atrophy: A large retrospective study from China
ConclusionOur study elucidated insight into the comprehensive management and profile of different types of SMA patients in China, providing a clinical basis for assessing the efficacy of new therapies. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Long-term neurorehabilitation outcomes of pediatric vs. adult onset acquired brain injury
ConclusionsThis study demonstrates the positive and enduring benefits of holistic, milieu-oriented neurorehabilitation for survivors of pediatric onset ABI regardless of the time between initial injury and engagement in rehabilitative therapies. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 20, 2022 Category: Neurology Source Type: research

Case report: Alexander's disease with “head drop” as the main symptom and literature review
Alexander's disease (AxD) is a rare autosomal dominant hereditary disorder that is caused by the mutations in the GFAP gene, which encodes the glial fibrillary acidic protein (GFAP). This neurogenerative disease has many clinical manifestations, and the onset of disease spans a wide range of ages, from newborns to children, adults, and even the elderly. An overaccumulation of the expression of GFAP has a close causal relationship with the pathogenesis of Alexander's disease. Usually, the disease has severe morbidity and high mortality, and can be divided into three distinct subgroups that are based on the age of clinical p...
Source: Frontiers in Neurology - December 19, 2022 Category: Neurology Source Type: research