Effect of concomitant usage of alteplase and mechanical thrombectomy for M1 middle cerebral artery occlusion on clinical outcome: a retrospective analysis of 457 patients from two centers
ConclusionUtilization of alteplase alongside EVT for MCA M1 occlusion did not result in excessive ICH occurrences or clinical deterioration. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 28, 2024 Category: Neurology Source Type: research
Association between Sj ögren syndrome, sociodemographic factors, comorbid conditions, and optic neuritis: a Taiwanese population-based study
DiscussionOur findings strongly support the existence of an association between Sjögren syndrome, rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, systemic lupus erythematosus, granulomatous vasculitis, human herpes viral infection, tuberculosis, and optic neuritis. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 27, 2024 Category: Neurology Source Type: research
A systematic review of the effectiveness of epilepsy education programs on knowledge, attitudes, and skills among primary school learners
Epilepsy is a common neurological condition affecting primary school learners, often leading to misconceptions, stigma, and limited social inclusion. These misconceptions transpire because of a lack of knowledge regarding the condition and may lead to high school dropouts. This systematic review aimed to evaluate the effectiveness of epilepsy education programs on epilepsy-related knowledge and understanding, values and attitudes, and skills among primary school learners. A thorough search of electronic databases was conducted to identify relevant studies published between January 2000 and September 2023. Studies that sati...
Source: Frontiers in Neurology - February 27, 2024 Category: Neurology Source Type: research
Derivation and validation of a quantitative risk prediction model for weaning and extubation in neurocritical patients
ConclusionThese results suggest that the extubation risk prediction model constructed through quantitative scoring has good predictive accuracy and can provide a scientific basis for clinical practice, helping to assess and predict extubation risk, thereby improving the success rate of extubation and improving patient prognosis. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 27, 2024 Category: Neurology Source Type: research
Has collateral blood flow any effect on restenosis rate? Our experience
ConclusionsGood collateral circulation was significantly associated with restenosis in patients undergoing intracranial angioplasty, the residual stenosis rate tends to be 15.85% to reduce restenosis risk. Compared to patients with restenosis, those without restenosis have a low stroke risk during follow-up. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 27, 2024 Category: Neurology Source Type: research
Comparison of different rhythmic auditory stimuli on prefrontal cortex cortical activation during upper limb movement in patients with Parkinson ’s disease: a functional near-infrared spectroscopy study
ConclusionRAS may be a useful upper limb rehabilitation strategy for PD patients with upper limb dysfunction. At the same time, RAS with different rhythms also have different responses to PFC blood oxygen during upper limb movement in PD patients, so that we can design interventions for this kind of cortical mechanism. Identifying the neurophysiological mechanism of RAS on upper limb movement in PD patients may help clinicians customize rehabilitation methods for patients according to clues, so as to highly personalize upper limb training and optimize its effect. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 27, 2024 Category: Neurology Source Type: research
Predictors of non-primary auditory and vestibular symptom persistence following surgical repair of superior canal dehiscence syndrome
ConclusionsSurgical repair for SCDS offers meaningful reduction in the majority of auditory and vestibular symptoms. However, the persistence of certain, mostly non-primary, symptoms and the identification of potential associated factors including migraines, PTA thresholds, cVEMP threshold, bilateral SCD, and revision cases emphasize the importance of individualized patient counseling and management strategies. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Spasticity-Plus syndrome in multiple sclerosis patients in a tertiary hospital in Spain
ConclusionSpasticity-Plus syndrome was present in all the study population of patients with different MS phenotypes, and treated with nabiximols. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Acute histological reactions in the otolith organs to inner ear drug delivery through a cochlear implant
DiscussionA significant concern relates to the safety of cochlear implantation with regard to vestibular preservation and hearing. New advancements in electrode arrays, such as CI devices coupled with delivery pumps, pose a challenge in maintaining minimally traumatic surgical concept-based procedures without affecting the inner ear homeostasis. The implantation of this device may cause vestibular hydrops in the saccule, indicating that the longer the time of substance release, the greater the grade of hydrops evidenced at the saccular level. Apart from this finding, the risk of histological damage to the vestibule is low....
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Curative effect analysis of robot-assisted drainage surgery in treatment of spontaneous hypertensive brainstem hemorrhage
ConclusionBased on the results of this study, robot-assisted minimally invasive drainage of brain stem hematoma may significantly reduce mortality and improve prognosis. Surgery should be conducted for selected patients. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Clinical analysis of hyperbaric oxygen combined with subdural drilling and drainage in the management of subdural effusion type IV with intracranial infection in infant patients
ConclusionThe SDD is safe and effective for infant patients with intracranial infections through fluid replacement and intrathecal antibacterial. Hyperbaric oxygen is effective as an adjuvant therapy to promote brain re-expansion. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Editorial: Neuromodulation for pharmacoresistant epilepsy: from bench to bed
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
CT-based radiomics models predict spontaneous intracerebral hemorrhage expansion and are comparable with CT angiography spot sign
ConclusionRadiomics models based on NCCT and CTA images effectively predicted HE in patients with SICH. The predictive performances of the NCCT and CTA models were similar, with the NCCT model outperforming the spot sign model. These findings suggest that this approach has the potential to reduce the need for CTA examinations, thereby reducing radiation exposure and the use of contrast agents in future practice for the purpose of predicting hematoma expansion. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Identifying patients at risk for myasthenic crisis with hemogram and inflammation-related laboratory parameters – a pilot study
ConclusionThis pilot study provides proof of the concept that increased counts of basophils, neutrophils, leukocytes, and platelets may be associated with a higher risk of developing MC in patients with MG. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
Treatment and outcome analysis of patients with ruptured distal anterior cerebral artery aneurysms: a multicenter real-world study
ConclusionIn the reality of medical practice, neurosurgeons are more likely to choose clipping as the treatment for cases with WFNs classification than or equal to III. There was no difference between clipping and coiling in the two-year prognosis at discharge. High priority should be given to DACAA cases with WFNs grading (I-III), as better outcomes can be achieved. The sample size will continue to be enlarged in the future to obtain more accurate findings. Abstracts for reviews, technical notes, and historical vignettes do not need to be separated into sections. They should begin with a clear statement of the paper’s p...
Source: Frontiers in Neurology - February 26, 2024 Category: Neurology Source Type: research
