Movement-specific keyboard playing for hand function in adolescents and young adults with acquired brain injury
This study aimed to examine the effects of movement-specific keyboard playing for improved hand function in adolescents and young adults with ABI.MethodA total of 23 patients with ABI participated in this study. Twelve were assigned to the intervention group and eleven to the control group. The intervention group engaged in movement-specific keyboard playing three to four times a week for 3 weeks in addition to standard care, while the control group received only standard care.ResultsThe results of a mixed model of repeated measures ANOVA showed that the time effects were significant in the functional independence measure,...
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Time-to-care metrics in patients with interhospital transfer for mechanical thrombectomy in north-east Germany: Primary telestroke centers in rural areas vs. primary stroke centers in a metropolitan area
ConclusionDespite considerable differences in the setting of stroke treatment in rural and metropolitan areas, overall time-to-care metrics were similar. Targets of process improvement should be door-to-needle times in RTCs, transfer organization, and door-to-groin times in CSCs wherever such process times are above best-practice models. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

A bibliometric analysis of telerehabilitation services for patients with stroke
ConclusionThe potential benefits and diversity of telerehabilitation are already highly visible from clinical studies, and further improvements in these technologies are expected to enhance functionality and accessibility for patients. More relevant research is encouraged to understand the barriers to increased adaptation of telerehabilitation services, which will finally translate into a significant therapeutic or preventive impact. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Analysis of the wall thickness of intracranial aneurysms: Can computational fluid dynamics detect the translucent areas of saccular intracranial aneurysms and predict the rupture risk preoperatively?
ConclusionsThe Ansys software Polyflow module could detect whether the unruptured aneurysms were translucent and predict the rupture risk and rupture point.Clinical trial registrationhttps://clinicaltrials.gov/, Identifier, NCT03133624. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Cerebral venous sinus thrombosis in traumatic brain injury: A systematic review of its complications, effect on mortality, diagnostic and therapeutic management, and follow-up
ConclusionCurrently, the available evidence is insufficient for evidence-based treatment of CVST in the setting of TBI. However, there are clear indications in the presently available literature that CVST in TBI is associated with complications and increased mortality, and this indicates that management options for the condition must be considered. Further studies are needed to confirm the effects of CVST on TBI patients and to provide evidence to support management decisions.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: PROSPERO [CRD42021247833]. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Brain-computer interface combined with mental practice and occupational therapy enhances upper limb motor recovery, activities of daily living, and participation in subacute stroke
ConclusionBCI combined with MP and OT is a promising tool for promoting sensorimotor recovery of the upper limb and functional independence in subacute post-stroke survivors. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Perspective: Disentangling the effects of tES on neurovascular unit
Transcranial electrical stimulation (tES) can modulate the neurovascular unit, including the perivascular space morphology, but the mechanisms are unclear. In this perspective article, we used an open-source “rsHRF toolbox” and an open-source functional magnetic resonance imaging (fMRI) transcranial direct current stimulation (tDCS) data set to show the effects of tDCS on the temporal profile of the haemodynamic response function (HRF). We investigated the effects of tDCS in the gray matter and at three regions of interest in the gray matter, namely, the anodal electrode (FC5), cathodal electrode (FP2), and an independ...
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Daily blood pressure variability in relation to neurological functional outcomes after acute ischemic stroke
ConclusionIrrespective of BP level, elevated daily systolic BPV and diastolic BPV in AIS were associated with an increased risk of adverse outcomes within 3 months. We also discovered a U-shaped association between the mean BP and adverse clinical outcomes. These findings suggested that BPV should be a risk factor for adverse outcomes after ischemic stroke, which provided new insight into BP management strategy. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Editorial: Novel imaging technologies for neuroinflammation
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Editorial: Acute and chronic effects of sub-concussion on brain function
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Autonomic dysfunction in epilepsy mouse models with implications for SUDEP research
Epilepsy has a high prevalence and can severely impair quality of life and increase the risk of premature death. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in drug-resistant epilepsy and most often results from respiratory and cardiac impairments due to brainstem dysfunction. Epileptic activity can spread widely, influencing neuronal activity in regions outside the epileptic network. The brainstem controls cardiorespiratory activity and arousal and reciprocally connects to cortical, diencephalic, and spinal cord areas. Epileptic activity can propagate trans-synaptically or via spreading depre...
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Language reorganization patterns in global aphasia –evidence from fNIRS
ConclusionThe left SMG plays a critical role in the language function of patients with global aphasia, especially in their abilities to name and repeat. fNIRS is a promising approach to revealing the changes in brain activities in patients with aphasia, and we believe it will contribute to a deeper understanding of the neurological mechanisms and the establishment of a novel treatment approach for global aphasia. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Vagus nerve stimulation for pharmacoresistant epilepsy secondary to encephalomalacia: A single-center retrospective study
ConclusionThe results demonstrated the effectiveness and safety of VNS therapy in patients with pharmacoresistant epilepsy secondary to encephalomalacia. Patients with seizure onset in adults (>18 years old), unilateral IEDs, or unilateral encephalomalacia on MRI were found to have better seizure outcomes after VNS therapy. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Acupuncture for mild cognitive impairment: A systematic review with meta-analysis and trial sequential analysis
ConclusionAcupuncture appears to be an effective clinical application method for improving OCF in patients with MCI. However, due to low-quality evidence, more relevant and high-quality research is needed in this field.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021291284, PROSPERO, No. CRD42021291284. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research

Utility of movement disorder society-unified Parkinson's disease rating scale for evaluating effect of subthalamic nucleus deep brain stimulation
ConclusionThe present preliminary study indicated that the utility of the MDS-UPDRS in evaluating motor function before and after STN-DBS demonstrates its potential equivalency to the UPDRS. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research