Which gait training intervention can most effectively improve gait ability in patients with cerebral palsy? A systematic review and network meta-analysis
ConclusionThis study suggested that BWSTT was optimal in increasing the gait velocity and RAGT was optimal in optimizing GMFM in persons with CP. Impacted by the limitations of the number and quality of studies, randomized controlled trials with larger sample sizes, multiple centers, and high quality should be conducted to validate the above conclusion. Further studies will be required to focus on the total duration of the intervention, duration and frequency of sessions, and intensity that are optimal for the promotion of gait ability in this population.Systematic review registrationhttps://doi.org/10.37766/inplasy2022.10...
Source: Frontiers in Neurology - January 10, 2023 Category: Neurology Source Type: research

Corrigendum: Case report: Cryptogenic giant brain abscess caused by Providencia rettgeri mimicking stroke and tumor in a patient with impaired immunity
(Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Sleep disturbance in post COVID-19 conditions: Prevalence and quality of life
Post COVID-19 conditions are complaints and symptoms in patients with a history of probable or confirmed COVID-19 after 3 months of the onset of COVID-19 and last at least 2 months. About 10–20% of people may experience post COVID-19 conditions, one of which is sleep disturbance. There is a wide range of prevalence of sleep disturbances from 6% to more than 70%. An online survey of the post COVID-19 conditions in various countries showed that 78.58% of subjects had sleep disturbances, including insomnia, sleep-disordered breathing, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, parasomnias, ...
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Exploring the role of immune checkpoint inhibitors in the etiology of myasthenia gravis and Lambert-Eaton myasthenic syndrome: A systematic review
ConclusionsThere is a paucity of evidence in support of an etiological relationship between ICIs and MG/LEMS, due largely to the lack of mechanistic studies and/or prospective clinical trials with relevant study endpoints. The current literature is dominated by case reports and retrospective cohort studies, which inherently yield only low-level evidence, supporting the need for further work in this area. A role of ICIs in the etiology of MG/LEMS remains plausible, arguing for continued vigilance for irAEs in patients treated with these drugs. We argue that there is a need for future mechanistic, high quality, large-scale s...
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Efficacy of Chinese herbal medicine on poststroke depression in animal models: A systematic review and meta-analysis
ConclusionOur results suggest that CHM could significantly improve depression-like behavior and neurological function in animals with PSD. The current results should be interpreted with caution because only animal studies were included. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Characterization of a lactate metabolism-related signature for evaluation of immune features and prediction prognosis in glioma
ConclusionWe explored the characteristics of LMGs in glioma and proposed an LMG-based signature. This prognostic model could predict the survival of patients with glioma and help clinical oncologists plan more individualized and effective therapeutic regimens. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Dynamic postural balance indices can help discriminate between patients with multiple system atrophy and Parkinson's disease
ConclusionThe dynamic posturographic variables with significant differences between patients with PD and those with MSA imply that patients with MSA have worse postural control ability in the medial-lateral (ML) direction compared to patients with PD. The obtained dynamic indices may help supplemental clinical evaluation to discriminate between patients with MSA and those with PD. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Acupuncture for neuropathic pain: A meta-analysis of randomized control trials
ConclusionThe acupuncture group had higher effectiveness than sham intervention or blank control for changes in pain intensity, but there is no significant difference between acupuncture and conventional treatments in treating NP. The acupuncture-induced adverse events were mild and reversible. However, the interpretation of our results should be performed cautiously due to the low methodological quality of selected publications.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022306461. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Mechanical thrombectomy for acute multivessel occlusions with duplicated middle cerebral artery: A case report
We report a case of acute anterior multivessel occlusions patient with duplicated middle cerebral artery. Combined balloon guide catheter with stent retriever and aspiration approach has gained complete revascularization and good functional outcomes at 3 months follow-up. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Clinical study on endovascular recanalization of non-acute symptomatic middle cerebral artery occlusion
ConclusionEndovascular recanalization may be feasible and safe in well-selected patients with non-acute symptomatic middle cerebral artery occlusion, especially in the low- and medium-risk groups. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Case report: Bilateral globus pallidus lesions and delayed progressive leukoencephalopathy in COVID-19: Effects of hypoxia alone or combination of hypoxia and inflammation?
ConclusionTo the best of our knowledge, this is the first report of post–COVID-19 with bilateral symmetric contrast-enhancing necrotic lesions of globus pallidus with delayed diffuse supratentorial leukoencephalopathy with microhemorrhages without concurrent hypoxia or reported preceding symptoms suggestive of hypoxia. We suspect that these inflammatory mechanisms might be triggered by prior COVID-19 exposure/infection. Furthermore, the role of the cross-talk between inflammation and clinically mild or silent hypoxia linked to prior COVID-19 infection cannot be excluded. Awareness of these post–COVID-19 neurological se...
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Persistent pain and numbness in the extremities of an adult due to paraneoplastic peripheral neuropathy caused by olfactory neuroblastoma: A case report
ConclusionOur case not only expanded the clinical characteristics of ONB but also highlighted the importance of early and comprehensive tumor screening for the diagnosis of PPN. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Association of baseline core volume and early midline shift in acute stroke patients with a large ischaemic core
ConclusionIn patients with an acute LIC following EVT, a pretreatment infarct core volume > 40 ml based on an rCBF < 15% showed good predictive value for early MLS occurrence. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Newborn screening for X-linked adrenoleukodystrophy in Italy: Diagnostic algorithm and disease monitoring
ConclusionThe primary aim of this study was to develop a model able to improve the early diagnosis and subsequent follow-up and timely treatment of X-ALD.EthicsThe study was approved by the local ethics committee. The research was conducted in the absence of any commercial or financial relationship that could be construed as a potential conflict of interest. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research

Application of drug-induced sleep endoscopy in predicting the outcomes of velopharyngeal surgery in adult patients with Friedman stage II and III obstructive sleep apnea syndrome
ConclusionThe VA-CP and GA-CD in DISE examination are valuable for predicting the treatment outcomes of velopharyngeal surgery in patients with Friedman stage II and III OSAS. Patients with lateral VA-CP and grade I GA-CD are appropriate candidates for velopharyngeal surgery. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - January 9, 2023 Category: Neurology Source Type: research