Metabolites: a converging node of host and microbe to explain meta-organism
Meta-organisms encompassing the host and resident microbiota play a significant role in combatting diseases and responding to stress. Hence, there is growing traction to build a knowledge base about this ecosystem, particularly to characterize the bidirectional relationship between the host and microbiota. In this context, metabolomics has emerged as the major converging node of this entire ecosystem. Systematic comprehension of this resourceful omics component can elucidate the organism-specific response trajectory and the communication grid across the ecosystem embodying meta-organisms. Translating this knowledge into de...
Source: Frontiers in Microbiology - March 5, 2024 Category: Microbiology Source Type: research
Metagenomic evidence for antibiotic-associated actinomycetes in the Karamay Gobi region
This study provides valuable theoretical support for future in-depth research. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 5, 2024 Category: Microbiology Source Type: research
Fecal microbiota colonization dynamics in dairy heifers associated with early-life rumen microbiota modulation and gut health
In conclusion, early-life microbiota modulation shows potential in ruminant development. However, a more targeted approach with bacteria adapted to the hindgut environment may be necessary to modulate hindgut effectively. This research contributes to our understanding of the complex relationship between gut microbiota and calf health and growth. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 5, 2024 Category: Microbiology Source Type: research
Activities of aztreonam in combination with several novel β-lactam-β-lactamase inhibitor combinations against carbapenem-resistant Klebsiella pneumoniae strains coproducing KPC and NDM
Isolates coproducing serine/metallo-carbapenems are a serious emerging public health threat, given their rapid dissemination and the limited number of treatment options. The purposes of this study were to evaluate the in vitro antibacterial activity of novel β-lactam-β-lactamase inhibitor combinations (BLBLIs) against carbapenem-resistant Klebsiella pneumoniae (CRKP) coproducing metallo-β-lactamase and serine-β-lactamase, and to explore their effects in combination with aztreonam, meropenem, or polymyxin in order to identify the best therapeutic options. Four CRKP isolates coproducing K. pneumoniae carbapenemase (KPC) ...
Source: Frontiers in Microbiology - March 5, 2024 Category: Microbiology Source Type: research
Editorial: Iron metabolism and biochemical cycling mediated by microorganisms
(Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 5, 2024 Category: Microbiology Source Type: research
