Assessment of new-onset heart failure prediction in a diabetic population using left ventricular global strain: a prospective cohort study based on UK Biobank
ConclusionLV-GRS, LV-GCS, and LV-GLS is significantly related to new-onset HF in patients with diabetes at 5 and 10 years. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
On the relation between oral contraceptive use and self-control
In two studies we examined the relation between oral contraceptive (OC) use and self-reported levels of self-control in undergraduate women using OCs (Study 1: OC group N = 399, Study 2: OC group N = 288) and naturally cycling women not using any form of hormonal contraceptives (Study 1: Non-OC group N = 964, Study 2: Non-OC group N = 997). We assessed the self-overriding aspect of self-control using the Brief Self-Control Scale (BSCS) and strategies for self-regulation using the Regulatory Mode Scale (RMS), which separately measures the tendency to assess one’s progress towards a goal (assessment), and the tendency to e...
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Double pituitary adenomas: report of two cases and systematic review of the literature
ConclusionsThe double lesion detected by surgical exploration is independently associated with a better prognosis for DPA patients. Comprehensive intraoperative exploration are crucial measures to avoid missing causative lesions. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Melatonin ’s effect on hair follicles in a goat (Capra hircus) animal model
This study will provide theoretical guidance for the cashmere industry and will be informative for human alopecia research. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Testosterone does not mediate the correlation between dietary inflammation and serum klotho levels among males: insights from NHANES database
This study aims to investigate the potential causal link of testosterone between DII and S-Klotho in males.MethodsWe utilized data from National Health and Nutrition Examination Survey (NHANES) which focused on male participants from 2013-2016. Mediation analyses were used to investigate the effects of testosterone (TT), free testosterone (FT), and free androgen index (FAI) on the DII-S-Klotho relationship, using three modes adjusting for covariates.ResultsMediation analysis unveiled a significant inverse correlation between DII and S-Klotho levels (model 1: c = -14.78, p = 0.046). The interaction between DII and S-Klotho ...
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Non-linear associations of atherogenic index of plasma with prediabetes and type 2 diabetes mellitus among Chinese adults aged 45 years and above: a cross-sectional study from CHARLS
ConclusionsThis study demonstrated non-linear positive associations of AIP with the risk of prediabetes and T2DM among participants ≥ 45 years of age in China. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Characterization of a novel fast-growing zebrafish: a new approach to growth hormone transgenesis
In this study, we characterized the growth and reproduction of these transgenic LHp-GH zebrafish using hormonal and physiological parameters. Our findings reveal that LHp-GH fish exhibited accelerated growth in both length and weight, along with a lower feed conversion ratio, indicating more efficient feed utilization, all while maintaining unchanged body proportions. These fish demonstrated higher expression levels of LH and GH in the pituitary and elevated IGF-1 levels in the liver compared to wild-type fish. An examination of reproductive function in LHp-GH fish unveiled lower pituitary LH and FSH contents, smaller foll...
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Analysis of urinary potassium isotopes and association with pancreatic health: healthy, diabetic and cancerous states
ConclusionAlthough the K isotope results should be considered exploratory and hypothesis-generating and future studies should focus on larger sample size and δ41K analysis of other K-disrupting diseases (e.g., chronic kidney disease), our data hold great promise for K isotopes as disease marker. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 2, 2024 Category: Endocrinology Source Type: research
Editorial: Impaired bone healing due to bone disuse and osteometabolic disorders
(Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Editorial: Short stature: beyond growth hormone
(Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Brain magnetic resonance imaging review suggests unrecognised hypoglycaemia in childhood
ConclusionsWe have identified the existence of unrecognised childhood hypoglycaemia through neuroimaging review. This study highlights the need for heightened awareness of early life hypoglycaemia to prevent adverse neurological outcomes later in childhood. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Role of CRH in colitis and colitis-associated cancer: a combinative result of central and peripheral effects?
Corticotropin-releasing factor family peptides (CRF peptides) comprise corticotropin releasing hormone (CRH), urocortin (UCN1), UCN2 and UCN3. CRH is first isolated in the brain and later with UCNs found in many peripheral cells/tissues including the colon. CRH and UCNs function via the two types of receptors, CRF1 and CRF2, with CRH mainly acting on CRF1, UCN1 on both CRF1 &CRF2 and UCN2-3 on CRF2. Compiling evidence shows that CRH participates in inflammation and cancers via both indirect central effects related to stress response and direct peripheral influence. CRH, as a stress-response mediator, plays a significan...
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Total muscle-to-fat ratio influences urinary incontinence in United States adult women: a population-based study
ConclusionA high tMFR serves as a protective factor against UI in women. Furthermore, lymphocyte might be involved in the relationship between tMFR and female UI. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Exploring deep learning radiomics for classifying osteoporotic vertebral fractures in X-ray images
ConclusionThe DLR model, based on the RadImageNet dataset, outperformed the ImageNet model in predicting the classification of OVFs, with generalizability confirmed in the prospective validation set. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study
ConclusionThis study determined four circulating inflammatory proteins that affected the occurrence of T2D, providing opportunities for the early prevention and innovative therapy of type 2 diabetes and its complications. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 28, 2024 Category: Endocrinology Source Type: research
