Molecular targets for anti-oxidative protection of a çaí berry against diabetes myocardial ischemia/reperfusion injury
In this study, we clearly demonstrated that açaí treatment was able to reduce biomarkers of myocardial damage, infarct size, and apoptotic process. Moreover, açaí administrations reduced inflammatory and oxidative response, modulating Nf-kB and Nrf2 pathways. These results suggest that açai berry supplementation could represent a useful strategy for pathological events associated to MIRI.PMID:37609799 | DOI:10.1080/10715762.2023.2243032 (Source: Free Radical Research)
Source: Free Radical Research - August 23, 2023 Category: Research Authors: Daniela Impellizzeri Marika Cordaro Rosalba Siracusa Roberta Fusco Alessio Filippo Peritore Enrico Gugliandolo Tiziana Genovese Rosalia Crupi Livia Interdonato Maurizio Evangelista Rosanna Di Paola Salvatore Cuzzocrea Ramona D'Amico Source Type: research

Molecular targets for anti-oxidative protection of a çaí berry against diabetes myocardial ischemia/reperfusion injury
In this study, we clearly demonstrated that açaí treatment was able to reduce biomarkers of myocardial damage, infarct size and apoptotic process. Moreover, açaí administrations reduced inflammatory and oxidative response, modulating Nf-kB and Nrf2 pathways. These results suggest that açai berry supplementation could represent a useful strategy for pathological events associated to MIRI.PMID:37609799 | DOI:10.1080/10715762.2023.2243032 (Source: Free Radical Research)
Source: Free Radical Research - August 23, 2023 Category: Research Authors: Daniela Impellizzeri Marika Cordaro Rosalba Siracusa Roberta Fusco Alessio Filippo Peritore Enrico Gugliandolo Tiziana Genovese Rosalia Crupi Livia Interdonato Maurizio Evangelista Rosanna Di Paola Salvatore Cuzzocrea Ramona D'Amico Source Type: research

Fullerene C < sub > 60 < /sub > reduces acute lung injury by suppressing oxidative stress-mediated DMBA-induced apoptosis and autophagy by regulation of cytochrome-C/Caspase-3/Beclin-1/IL-1 α/HO-1/p53 signaling pathways in rats
The objective of this study was to evaluate the effect of fullerene C60 nanoparticles against 7,12-dimethylbenz[a]anthracene (DMBA)-induced lung tissue damage in rats. 15 Wistar albino (8 weeks old) female rats were assigned into four groups: Control Group (C), Fullerene C60, DMBA, and Fullerene C60+DMBA. The rats in the DMBA and Fullerene C60+DMBA groups were administered DMBA (45 mg/kg bw, oral gavage). The rats in Fullerene C60, DMBA and Fullerene C60+DMBA groups were administered with Fullerene C60 (1.7 mg/kg bw, oral gavage). Expression levels of cytochrome-c, caspase-3, beclin-1, IL-1α, HO-1 and p53 proteins in lung...
Source: Free Radical Research - August 16, 2023 Category: Research Authors: Seda Beyaz Abdullah Aslan Ozlem Gok Ibrahim Hanifi Ozercan Can Ali Agca Source Type: research