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Corrigendum to "Clozapine-N-oxide protects dopaminergic neurons against rotenone-induced neurotoxicity by preventing ferritinophagy-mediated ferroptosis" [Free Radic. Biol. Med. 212 (2024) 384-402]
Free Radic Biol Med. 2024 Feb 25;215:1. doi: 10.1016/j.freeradbiomed.2024.02.007. Online ahead of print.NO ABSTRACTPMID:38408401 | DOI:10.1016/j.freeradbiomed.2024.02.007 (Source: Free Radical Biology and Medicine)
Source: Free Radical Biology and Medicine - February 26, 2024 Category: Biology Authors: Qingquan Sun Yan Wang Liyan Hou Sheng Li Jau-Shyong Hong Qingshan Wang Jie Zhao Source Type: research

Allogeneic platelet-rich plasma inhibits ferroptosis in promoting wound repair of type 2 diabetic ulcers
Free Radic Biol Med. 2024 Feb 24:S0891-5849(24)00102-3. doi: 10.1016/j.freeradbiomed.2024.02.020. Online ahead of print.ABSTRACTIncreasing evidence has revealed the emerging role of ferroptosis in the pathophysiology of type 2 diabetes mellitus (T2DM) and its complications. Platelet-rich plasma (PRP) has been demonstrated to facilitate the healing of T2DM ulcers. However, the mechanism by which PRP repairs T2DM ulcers remains unclear. Here, we sought to investigate the interaction between PRP and ferroptosis in repairing T2DM ulcers. The results showed that the cellular activity, proliferation, and migration of fibroblasts...
Source: Free Radical Biology and Medicine - February 26, 2024 Category: Biology Authors: Danlian Zhou Qiu Liang Xiuyu Ge Jing Xu Source Type: research

Effects of dietary inorganic nitrate on blood pressure during and post exercise: A systematic review and meta-analysis of randomized placebo-controlled trials
CONCLUSIONS: NO3- ingestion prior to exercise attenuated the increases in SBP and DBP during exercise, and increased the decline in SBP after exercise. These results are dependent on factors that moderate the blood pressure responses (e.g., health status, type of exercise, resting blood pressure values).PMID:38403254 | DOI:10.1016/j.freeradbiomed.2024.02.011 (Source: Free Radical Biology and Medicine)
Source: Free Radical Biology and Medicine - February 25, 2024 Category: Biology Authors: Cicero Jonas R Benjamim Leonardo S Lopes da Silva Vitor E Valenti Leonardo S Gon çalves Andrey A Porto M árcio Fernando Tasinafo Júnior Jean-Philippe Walhin David M Garner Bruno Gualano Carlos R Bueno J únior Source Type: research

Vitamin E: Not only a single stereoisomer
Free Radic Biol Med. 2024 Feb 22:S0891-5849(24)00093-5. doi: 10.1016/j.freeradbiomed.2024.02.013. Online ahead of print.ABSTRACTThe recent publication by Azzi and colleagues puts forth the argument that only RRR-α-tocopherol should be considered as vitamin E from a physiological point of view. They base their argument primarily on the assertion that only this form has been used to treat stark vitamin E deficiency in humans (known as AVED, or Ataxia with Vitamin E Deficiency). Azzi et al. also argue that other chemically similar molecules, such as tocopherols other than α-tocopherol and tocotrienols do not provide vitamin...
Source: Free Radical Biology and Medicine - February 24, 2024 Category: Biology Authors: M Eggersdorfer K Schmidt S P éter J Richards B Winklhofer-Roob A Hahn U Oberm üller-Jevic Source Type: research

Aging hallmarks, biomarkers, and clocks for personalized medicine: (re)positioning the limelight
Free Radic Biol Med. 2024 Feb 21:S0891-5849(24)00092-3. doi: 10.1016/j.freeradbiomed.2024.02.012. Online ahead of print.ABSTRACTThe rapidly increasing aging prevalence, complexity, and heterogeneity pose the scientific and medical communities in front of challenges. These are delivered by gaps between basic and translational research, as well as between clinical practice guidelines to improve survival and absence of evidence on personalized strategies to improve functions, wellbeing and quality of life. The triumphs of aging science sheding more and more light on mechanisms of aging as well as those of medical and technolo...
Source: Free Radical Biology and Medicine - February 23, 2024 Category: Biology Authors: M Cristina Polidori Source Type: research

Therapeutic effect of mitochondrial transplantation on burn injury
In conclusion, our data indicate that MT exerts a therapeutic effect on burn injuries both in vitro and in vivo.PMID:38395090 | DOI:10.1016/j.freeradbiomed.2024.02.019 (Source: Free Radical Biology and Medicine)
Source: Free Radical Biology and Medicine - February 23, 2024 Category: Biology Authors: Zhen Li Xinhui Cao Zuohao Liu Fen Wu Changjun Lin Chun-Ming Wang Source Type: research

Systemic oxidative stress may be associated with reduced IgG antibody titers against SARS-cov-2 in vaccinated kidney transplant recipients: A post-hoc analysis of the RECOVAC-IR observational study
CONCLUSIONS: KTR show suboptimal serological responses to SARS-CoV-2 vaccination, which is inversely associated with serum R-SH, reflecting systemic oxidative stress. Albeit this association was not robust to relevant confounding factors, it may at least partially be involved in the inability of KTR to generate a positive serological response after SARS-CoV-2 vaccination.PMID:38395091 | DOI:10.1016/j.freeradbiomed.2024.02.018 (Source: Free Radical Biology and Medicine)
Source: Free Radical Biology and Medicine - February 23, 2024 Category: Biology Authors: Larissa E van Eijk Arno R Bourgonje A Lianne Messchendorp Marian L C Bulthuis Marjan Reinders-Luinge Berber Doornbos-van der Meer Johanna Westra Wilfred F A den Dunnen Jan-Luuk Hillebrands Jan-Stephan F Sanders Harry van Goor RECOVAC Collaborators Source Type: research