Expression Levels of Nerve Growth Factor and Its Receptors in Anterior Vaginal Wall in Postmenopausal Women With Pelvic Organ Prolapse
Conclusions The decreased expression of NGF and its receptors p75NTR and TrkA in vaginal anterior wall tissue of postmenopausal POP patients and the change of the ratio of 2 receptors may be related to the occurrence and development of POP. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Early and Consistent Improvements in Urinary Symptoms and Quality of Life With OnabotulinumtoxinA in Patients With Overactive Bladder and Urinary Incontinence: Results From a Randomized, Placebo-controlled, Phase IV Clinical Trial
Objectives This randomized, multicenter, placebo-controlled, phase IV study assessed the efficacy and tolerability of onabotulinumtoxinA in patients with overactive bladder. Methods Patients were randomized 1:1 to onabotulinumtoxinA 100 U or placebo. Assessments over 12 weeks included: change from baseline in urinary incontinence (UI) episodes/day; proportions of patients who achieved 100% and 50% or greater reductions in UI episodes/day; proportion of patients using no incontinence pads in the previous 24 hours; and changes from baseline in micturition frequency, nocturia, urgency UI, Incontinence-Quality of Li...
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Factors Associated With Long-Term Use of Percutaneous Tibial Nerve Stimulation for Management of Overactive Bladder Syndrome
Objectives The aims of the study were to estimate the rate of percutaneous tibial nerve stimulation maintenance therapy (PTNS-MT) among women with overactive bladder syndrome (OAB) and evaluate factors associated with long-term use of PTNS. Methods Patients who completed 12 weekly sessions of PTNS (PTNS-IN) for OAB between 2009 and 2016 within the Kaiser Permanente Northern California were identified using Current Procedural Terminology and International Classification of Diseases codes. Bivariate analysis was performed to compare demographic and clinical variables. A logistic regression model was used to determ...
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Patient Preferences and Knowledge Regarding Hysterectomy: A Study from the Fellows’ Pelvic Research Network (FPRN)®
Conclusions Patients prefer laparoscopic hysterectomy approach, although have limited understanding of vaginal hysterectomy. Higher health literacy levels are associated with increased knowledge of gynecology and hysterectomy routes, but were not found to influence patient preference for hysterectomy route. Overall, patients have limited knowledge of vaginal hysterectomy. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Video Virtual Clinical Encounters Versus Office Visits for Postoperative Care After Pelvic Organ Prolapse Surgery: A Randomized Clinical Trial
Conclusions For patients with pelvic organ prolapse undergoing reconstructive surgery, postoperative virtual clinical encounters via video conference technology are noninferior to traditional in-office clinical encounters with high levels of short-term patient satisfaction and no differences in postoperative health care utilization and complications rates. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Operationalizing Postdischarge Recovery From Laparoscopic Sacrocolpopexy for the Preoperative Consultative Visit
Conclusions Most study subjects were “significantly” recovered at 42 days after laparoscopic sacrocolpopexy using a PSR13 score of 80 or greater as a numeric threshold. There is a need to determine the population percentage of recovered study subjects at 30, 60, and beyond 90 days from laparoscopic sacrocolpopexy. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Regional Performance of Apical Support Procedures at Time of Hysterectomy for Benign Indications: What Is the Role of Surgeon Training?
Conclusions Even in patients with a preoperative diagnosis of uterovaginal prolapse, ASPs are not routinely performed at time of hysterectomy. Fellowship-trained surgeons were more likely to perform ASPs. Ongoing educational efforts during training and postgraduate at the national and regional level on the importance of reestablishing apical vaginal support at time of hysterectomy is needed to prevent incident and recurrent post-hysterectomy vaginal vault prolapse. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Factors Influencing Selection of Concomitant Total Versus Supracervical Hysterectomy at the Time of Sacrocolpopexy and Associated Perioperative Outcomes
The objective of this study was to describe national practice patterns of hysterectomy type performed with concurrent sacrocolpopexy and determine clinical factors associated with surgical route. Methods We used the National Surgical Quality Improvement Program database with hysterectomy data for this retrospective cohort study. We identified sacrocolpopexy cases from 2014 to 2016 with concurrent hysterectomy and stratified patients into supracervical hysterectomy (SCH) or total hysterectomy (TH). As a secondary analysis, we compared the laparoscopic subset of cases. We performed χ2 and backward stepwise logistic r...
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Therapeutic Suggestion in Postoperative Pain Control: A Randomized Controlled Trial
Conclusions No differences in postoperative pain, analgesic use, return of bowel and bladder function, or pelvic organ prolapse symptoms were noted in participants receiving perioperative therapeutic suggestion versus routine perioperative care. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

A Randomized Controlled Trial of a Multimedia Patient Education Tool for Stress Versus Urgency Urinary Incontinence
Objective The aim of this study was to determine whether there was a difference in patient education when comparing traditional conversation-based patient counseling with multimedia-based patient counseling about stress and urgency urinary incontinence. Methods Patients seeking treatment for urinary incontinence were randomized to traditional, conversation-based counseling from a physician regarding stress and urgency urinary incontinence (control group) or view a video (multimedia) as their counseling (treatment group). A vignette-based assessment of the patient’s knowledge of stress and urgency urinary incon...
Source: Female Pelvic Medicine and Reconstructive Surgery - June 24, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Dear Editor
No abstract available (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 1, 2021 Category: OBGYN Tags: Letter to the Editor Source Type: research

Rates of Sling Procedures and Revisions—A National Surgical Quality Improvement Program Database Study
Conclusions Our data suggest that MUS remain the preferred procedure for treatment of stress urinary incontinence despite the recent FDA communications with MUS representing 99% of sling procedures during the study period. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 1, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Genital Hiatus Size as a Predictor of Progression of Pelvic Organ Prolapse
This study aimed to determine if genital hiatus (GH) size is a predictor of worsening pelvic organ prolapse and a preference for a therapeutic intervention in women with pelvic organ prolapse who opt for expectant management over therapeutic intervention at their initial encounter. Methods This was a retrospective cohort study analyzing the GH size of women who opted for expectant management in the initial treatment of pelvic organ prolapse at one academic institution from 2002 to 2015. Participants were divided into 2 groups: (1) large GH was defined as ≥4 cm and (2) normal GH was defined as (Source: Female Pelvi...
Source: Female Pelvic Medicine and Reconstructive Surgery - June 1, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Unanticipated Uterine and Cervical Malignancy in Women Undergoing Hysterectomy for Uterovaginal Prolapse
Conclusions The risk of unexpected uterine cancer and cervical cancer in women undergoing hysterectomy for uterovaginal prolapse was relatively low but should be appropriately considered when counseling patients desiring uterine- or cervix-sparing procedures. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 1, 2021 Category: OBGYN Tags: Original Articles Source Type: research

Postoperative Admission, Readmission, and Complications for Patients 60 Years and Older Who Are Undergoing an Isolated Sling Procedure for Stress Incontinence: A Database Study
Conclusions Among patients 60 years and older, the risk of postoperative admission and readmission for patients undergoing a synthetic or autologous sling procedure is low and complications are uncommon. (Source: Female Pelvic Medicine and Reconstructive Surgery)
Source: Female Pelvic Medicine and Reconstructive Surgery - June 1, 2021 Category: OBGYN Tags: Original Articles Source Type: research