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Evaluating as-needed inhaled corticosteroid strategies in asthma: Expanding the benefits to mild asthma
Expert Rev Respir Med. 2023 Aug 14. doi: 10.1080/17476348.2023.2247973. Online ahead of print.ABSTRACTINTRODUCTION: Adherence to regular anti-inflammatory treatment is commonly low, and short-acting β2 agonist (SABA) overuse is common in patients with asthma, leading to an increased risk of asthma-related adverse events.AREAS COVERED: Given the pivotal role of inflammation in asthma, multiple as-needed inhaled corticosteroid (ICS)-containing therapies have been developed, leading to a reduction in asthma exacerbations and improvement in symptom control. Currently, as-needed ICS/formoterol is one of the most commonly avail...
Source: Expert Review of Respiratory Medicine - August 14, 2023 Category: Respiratory Medicine Authors: Tommaso Bigoni Franco Alfano Federico Baraldi Marco Contoli Alberto Papi Source Type: research

Diagnosis and management of pulmonary veno-occlusive disease
Expert Rev Respir Med. 2023 Aug 14. doi: 10.1080/17476348.2023.2247989. Online ahead of print.ABSTRACTINTRODUCTION: Pulmonary veno-occlusive disease (PVOD) is an orphan disease and uncommon etiology of pulmonary arterial hypertension (PAH) characterized by substantial small pulmonary vein and capillary involvement.AREAS COVERED: PVOD, also known as 'PAH with features of venous/capillary involvement' in the current ESC/ERS classification.EXPERT OPINION: In recent years, particular risk factors for PVOD have been recognized, including genetic susceptibilities and environmental factors (such as exposure to occupational organi...
Source: Expert Review of Respiratory Medicine - August 14, 2023 Category: Respiratory Medicine Authors: Sabina Solinas Ath énaïs Boucly Antoine Beurnier Mithum Kularatne Julien Grynblat M élanie Eyries Peter Dorfm üller Olivier Sitbon Marc Humbert David Montani Source Type: research

Personalised management and supporting individuals to live with their asthma in a primary care setting
Expert Rev Respir Med. 2023 Aug 3:1-20. doi: 10.1080/17476348.2023.2241357. Online ahead of print.ABSTRACTINTRODUCTION: Complementing recognition of biomedical phenotypes, a primary care approach to asthma care recognizes diversity of disease, health beliefs, and lifestyle at a population and individual level.AREAS COVERED: We review six aspects of personalized care particularly pertinent to primary care management of asthma: personalizing support for individuals living with asthma; targeting asthma care within populations; managing phenotypes of wheezy pre-school children; personalizing management to the individual; meeti...
Source: Expert Review of Respiratory Medicine - August 3, 2023 Category: Respiratory Medicine Authors: Hilary Pinnock Mike Noble David Lo Kirstie McClatchey Viv Marsh Chi Yan Hui Source Type: research

Up-to-date guidance towards improving medication adherence in patients with chronic obstructive pulmonary disease
Expert Rev Respir Med. 2023 Jul 28:1-8. doi: 10.1080/17476348.2023.2239708. Online ahead of print.ABSTRACTINTRODUCTION: Despite efficacious treatment for chronic obstructive pulmonary disease (COPD), medication adherence remains quite poor, with most estimates based on electronic monitoring devices ranging from 20-30%. This degree of nonadherence represents a significant missed opportunity to realize the benefits of treatment of this disease.AREAS COVERED: In this article, we review research on the prevalence of nonadherence among patients with COPD, the association of nonadherence with health outcomes, barriers to adheren...
Source: Expert Review of Respiratory Medicine - July 26, 2023 Category: Respiratory Medicine Authors: Meredith A Case Michelle N Eakin Source Type: research