Interstitial lung abnormality in COPD is associated with higher prevalence of antinuclear antibody
CONCLUSION: The presence of ILA in patients with COPD was associated with a higher prevalence of positive ANA. Patients with positive ANA tended to have lower FEV1, DLCO and lung volume.PMID:37698170 | DOI:10.1080/17476348.2023.2257135 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - September 12, 2023 Category: Respiratory Medicine Authors: Yujia Liu Yanwen Jiang Yongchang Sun Source Type: research

Interstitial lung abnormality in COPD is associated with higher prevalence of antinuclear antibody
CONCLUSION: The presence of ILA in patients with COPD was associated with a higher prevalence of positive ANA. Patients with positive ANA tended to have lower FEV1, DLCO and lung volume.PMID:37698170 | DOI:10.1080/17476348.2023.2257135 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - September 12, 2023 Category: Respiratory Medicine Authors: Yujia Liu Yanwen Jiang Yongchang Sun Source Type: research

Pneumothorax, pneumomediastinum, and subcutaneous emphysema in hospitalized COVID-19 patients: incidence, clinical characteristics, and outcomes
CONCLUSION: Although the occurrence of PTX/PNM/SCE in hospitalized COVID-19 patients was rare, it was associated with worse outcomes. Corticosteroids may contribute to the pathogenesis of these complications; however, further studies are needed to investigate this relationship in more detail.PMID:37675598 | DOI:10.1080/17476348.2023.2254689 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - September 7, 2023 Category: Respiratory Medicine Authors: Aleksandra Murawska Baptista Jorge Sinclair De Fr ías Trisha Singh Ananya Vasudhar Jacob Guzzino Waheed Khalili Aysun Tekin Vikas Bansal Rahul Kashyap William J Joyce Patricia A Lewis Devang Sanghavi Tatjana Gavrancic Pablo Moreno Franco Source Type: research

Pneumothorax, pneumomediastinum, and subcutaneous emphysema in hospitalized COVID-19 patients: incidence, clinical characteristics, and outcomes
CONCLUSION: Although the occurrence of PTX/PNM/SCE in hospitalized COVID-19 patients was rare, it was associated with worse outcomes. Corticosteroids may contribute to the pathogenesis of these complications; however, further studies are needed to investigate this relationship in more detail.PMID:37675598 | DOI:10.1080/17476348.2023.2254689 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - September 7, 2023 Category: Respiratory Medicine Authors: Aleksandra Murawska Baptista Jorge Sinclair De Fr ías Trisha Singh Ananya Vasudhar Jacob Guzzino Waheed Khalili Aysun Tekin Vikas Bansal Rahul Kashyap William J Joyce Patricia A Lewis Devang Sanghavi Tatjana Gavrancic Pablo Moreno Franco Source Type: research

The value of perioperative physical activity in older patients undergoing surgery for lung cancer
Expert Rev Respir Med. 2023 Sep 5. doi: 10.1080/17476348.2023.2255133. Online ahead of print.ABSTRACTINTRODUCTION: With a median age at diagnosis of 70, lung cancer represents an enormous public health problem among older Americans. An estimated 19,000 people age 65 and older undergo lung cancer surgery annually in the US. Older adults undergoing lung cancer surgery are often frail with limited physiologic reserves, multi-morbidities, and functional impairments. Physical function, dyspnea, and quality of life return to baseline slower in older adults compared with younger adults after lung surgery.AREAS COVERED: In this re...
Source: Expert Review of Respiratory Medicine - September 5, 2023 Category: Respiratory Medicine Authors: Dan J Raz Jae Y Kim Loretta Erhunwmunesee Sherry Hite Gouri Varatkar Virginia Sun Source Type: research

Mechanisms underlying corticosteroid resistance in patients with asthma: a review of current knowledge
Expert Rev Respir Med. 2023 Sep 4:1-15. doi: 10.1080/17476348.2023.2255124. Online ahead of print.ABSTRACTINTRODUCTION: Corticosteroids are the most cost-effective anti-inflammatory drugs available for the treatment of asthma. Despite their effectiveness, several asthmatic patients have corticosteroid resistance or insensitivity and exhibit a poor response. Corticosteroid insensitivity implies a poor prognosis due to challenges in finding alternative therapeutic options for asthma.AREAS COVERED: In this review, we describe asthma phenotypes and endotypes, as well as their differential responsiveness to corticosteroids. In ...
Source: Expert Review of Respiratory Medicine - September 1, 2023 Category: Respiratory Medicine Authors: Javier Milara Anselm Morell In és Roger Paula Montero Julio Cortijo Source Type: research