Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board
CONCLUSIONS: PwCF on CFTR modulators are questioning the necessity of continuing chronic medications and therapies. Physicians are urged to carefully consider the balance between simplifying antibiotic treatment and the risk of clinical deterioration due to bacterial infections when making treatment decisions. Furthermore, the development and global harmonization of diagnostic tools for chronic lung damage and treatment guidelines are crucial to justify the demanding routines that PwCF must endure to manage their condition.The heterogeneity in patient journeys, diagnostic challenges, treatment complexity, and issues relate...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Simone Gambazza Valerie Storms Vinay Purohit Source Type: research

What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review
Expert Rev Respir Med. 2023 Oct 10. doi: 10.1080/17476348.2023.2268509. Online ahead of print.ABSTRACTINTRODUCTION: Immune-checkpoint inhibitors (IO) have significantly improved outcomes of patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the first-line agents for advanced disease. However, resistance remains a significant clinical challenge, limiting their effectiveness.AREAS COVERED: Hereby, we addressed standard and innovative therapeutic approaches for NSCLC patients experiencing progression after IO treatment, discussing the emerging resistance mechanisms and the ongoing efforts to over...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Alberto Giuseppe Agostara Laura Roazzi Federica Villa Rebecca Romano' Daniele Piscazzi Francesca Martinelli Gabriele Ciarlo Sara Oresti Francesca Travaglini Alessandro Marando Andrea Sartore Bianchi Laura Giannetta Giulio Cerea Salvatore Siena Elio Gregor Source Type: research

Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board
CONCLUSIONS: PwCF on CFTR modulators are questioning the necessity of continuing chronic medications and therapies. Physicians are urged to carefully consider the balance between simplifying antibiotic treatment and the risk of clinical deterioration due to bacterial infections when making treatment decisions. Furthermore, the development and global harmonization of diagnostic tools for chronic lung damage and treatment guidelines are crucial to justify the demanding routines that PwCF must endure to manage their condition.The heterogeneity in patient journeys, diagnostic challenges, treatment complexity, and issues relate...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Simone Gambazza Valerie Storms Vinay Purohit Source Type: research

What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review
Expert Rev Respir Med. 2023 Oct 10. doi: 10.1080/17476348.2023.2268509. Online ahead of print.ABSTRACTINTRODUCTION: Immune-checkpoint inhibitors (IO) have significantly improved outcomes of patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the first-line agents for advanced disease. However, resistance remains a significant clinical challenge, limiting their effectiveness.AREAS COVERED: Hereby, we addressed standard and innovative therapeutic approaches for NSCLC patients experiencing progression after IO treatment, discussing the emerging resistance mechanisms and the ongoing efforts to over...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Alberto Giuseppe Agostara Laura Roazzi Federica Villa Rebecca Romano' Daniele Piscazzi Francesca Martinelli Gabriele Ciarlo Sara Oresti Francesca Travaglini Alessandro Marando Andrea Sartore Bianchi Laura Giannetta Giulio Cerea Salvatore Siena Elio Gregor Source Type: research

Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board
CONCLUSIONS: PwCF on CFTR modulators are questioning the necessity of continuing chronic medications and therapies. Physicians are urged to carefully consider the balance between simplifying antibiotic treatment and the risk of clinical deterioration due to bacterial infections when making treatment decisions. Furthermore, the development and global harmonization of diagnostic tools for chronic lung damage and treatment guidelines are crucial to justify the demanding routines that PwCF must endure to manage their condition.The heterogeneity in patient journeys, diagnostic challenges, treatment complexity, and issues relate...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Simone Gambazza Valerie Storms Vinay Purohit Source Type: research

What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review
Expert Rev Respir Med. 2023 Oct 10. doi: 10.1080/17476348.2023.2268509. Online ahead of print.ABSTRACTINTRODUCTION: Immune-checkpoint inhibitors (IO) have significantly improved outcomes of patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the first-line agents for advanced disease. However, resistance remains a significant clinical challenge, limiting their effectiveness.AREAS COVERED: Hereby, we addressed standard and innovative therapeutic approaches for NSCLC patients experiencing progression after IO treatment, discussing the emerging resistance mechanisms and the ongoing efforts to over...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Alberto Giuseppe Agostara Laura Roazzi Federica Villa Rebecca Romano' Daniele Piscazzi Francesca Martinelli Gabriele Ciarlo Sara Oresti Francesca Travaglini Alessandro Marando Andrea Sartore Bianchi Laura Giannetta Giulio Cerea Salvatore Siena Elio Gregor Source Type: research

Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board
CONCLUSIONS: PwCF on CFTR modulators are questioning the necessity of continuing chronic medications and therapies. Physicians are urged to carefully consider the balance between simplifying antibiotic treatment and the risk of clinical deterioration due to bacterial infections when making treatment decisions. Furthermore, the development and global harmonization of diagnostic tools for chronic lung damage and treatment guidelines are crucial to justify the demanding routines that PwCF must endure to manage their condition.The heterogeneity in patient journeys, diagnostic challenges, treatment complexity, and issues relate...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Simone Gambazza Valerie Storms Vinay Purohit Source Type: research

What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review
Expert Rev Respir Med. 2023 Oct 10. doi: 10.1080/17476348.2023.2268509. Online ahead of print.ABSTRACTINTRODUCTION: Immune-checkpoint inhibitors (IO) have significantly improved outcomes of patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the first-line agents for advanced disease. However, resistance remains a significant clinical challenge, limiting their effectiveness.AREAS COVERED: Hereby, we addressed standard and innovative therapeutic approaches for NSCLC patients experiencing progression after IO treatment, discussing the emerging resistance mechanisms and the ongoing efforts to over...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Alberto Giuseppe Agostara Laura Roazzi Federica Villa Rebecca Romano' Daniele Piscazzi Francesca Martinelli Gabriele Ciarlo Sara Oresti Francesca Travaglini Alessandro Marando Andrea Sartore Bianchi Laura Giannetta Giulio Cerea Salvatore Siena Elio Gregor Source Type: research

Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board
CONCLUSIONS: PwCF on CFTR modulators are questioning the necessity of continuing chronic medications and therapies. Physicians are urged to carefully consider the balance between simplifying antibiotic treatment and the risk of clinical deterioration due to bacterial infections when making treatment decisions. Furthermore, the development and global harmonization of diagnostic tools for chronic lung damage and treatment guidelines are crucial to justify the demanding routines that PwCF must endure to manage their condition.The heterogeneity in patient journeys, diagnostic challenges, treatment complexity, and issues relate...
Source: Expert Review of Respiratory Medicine - October 11, 2023 Category: Respiratory Medicine Authors: Simone Gambazza Valerie Storms Vinay Purohit Source Type: research

Is there cardiac autonomic dysfunction in children and adolescents with exercise-induced bronchospasm?
CONCLUSION: Young asthmatics with EIBA present a delay in the increase of the parasympathetic component after EVH when compared to asthmatics without EIBA.PMID:37795708 | DOI:10.1080/17476348.2023.2265819 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - October 5, 2023 Category: Respiratory Medicine Authors: Polyanna Guerra Chaves Quirino Jos é Ângelo Rizzo Steve Hunter Edil de Albuquerque Rodrigues Filho Emanuel Sarinho Camila Matias de Almeida Santos Decio Medeiros Emilia Chagas Costa Alexandre S érgio Silva Breno Quintella Farah Marco Aur élio de Valoi Source Type: research

Is there cardiac autonomic dysfunction in children and adolescents with exercise-induced bronchoconstriction?
CONCLUSION: Young asthmatics with EIBA present a delay in the increase of the parasympathetic component after EVH when compared to asthmatics without EIBA.PMID:37795708 | DOI:10.1080/17476348.2023.2265819 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - October 5, 2023 Category: Respiratory Medicine Authors: Polyanna Guerra Chaves Quirino Jos é Ângelo Rizzo Steve Hunter Edilde Albuquerque Rodrigues Filho Emanuel Sarinho Camila Matiasde Almeida Santos Decio Medeiros Emilia Chagas Costa Alexandre S érgio Silva Breno Quintella Farah Marco Aur éliode Valois C Source Type: research

Thoracic ultrasound-guided real-time pleural biopsy in the diagnosis of pleural diseases: a systematic review and meta-analysis
CONCLUSION: Conventional TUSPB has good pooled diagnostic yields and high safety. CEUS and UE are promising guidance tools for pleural biopsy with the potential to increase diagnostic yield.PMID:37787485 | DOI:10.1080/17476348.2023.2266377 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - October 3, 2023 Category: Respiratory Medicine Authors: Qin Zhang Ming-Ming Deng Xue-Lian Li Ye Lu Gang Hou Source Type: research