A narrative review of nontuberculous mycobacterial pulmonary disease: microbiology, epidemiology, diagnosis, and management challenges
Expert Rev Respir Med. 2023 Nov 14. doi: 10.1080/17476348.2023.2283135. Online ahead of print.ABSTRACTINTRODUCTION: Nontuberculous mycobacteria (NTM) are a diverse group of mycobacterial species that are ubiquitous in the environment. They are opportunistic pathogens that can cause a range of diseases in both animals and humans, especially in individuals with underlying structural lung disease or compromised immune systems.AREAS COVERED: This paper provides an in-depth analysis of NTM infections, including microbiology, environmental sources and transmission pathways, risk factors for disease, epidemiology, clinical manife...
Source: Expert Review of Respiratory Medicine - November 14, 2023 Category: Respiratory Medicine Authors: Kamal Hamed Glenn Tillotson Source Type: research

Role of radiation in oligometastases and oligoprogression in metastatic non-small cell lung cancer: consensus and controversy
Expert Rev Respir Med. 2023 Nov 14. doi: 10.1080/17476348.2023.2284362. Online ahead of print.ABSTRACTINTRODUCTION: The oligometastatic state in non-small cell lung cancer (NSCLC) has recently become well-established. However, the specific definition of oligometastases remains unclear. Several smaller randomized studies have investigated the safety and efficacy of radiation as metastasis-directed therapy (MDT) in oligometastatic NSCLC, which have led the way to larger studies currently accruing patients globally.AREAS COVERED: This review covers the definitions of 'oligometastases' and explains why the oligometastatic stat...
Source: Expert Review of Respiratory Medicine - November 14, 2023 Category: Respiratory Medicine Authors: Abhishek Kumar Joseph K Salama Source Type: research

Endobronchial ultrasound with a guide sheath during bronchoscopy for peripheral pulmonary lesions
Expert Rev Respir Med. 2023 Nov 12:1-8. doi: 10.1080/17476348.2023.2278605. Online ahead of print.ABSTRACTINTRODUCTION: Radial probe endobronchial ultrasound (rEBUS) improves the diagnostic yield of peripheral pulmonary lesions (PPLs). A notable methodological limitation of rEBUS is that it does not provide real-time images during transbronchial biopsy (TBB) procedures. To overcome this limitation, a guide sheath (GS) method was developed.AREAS COVERED: This review covers the procedures and complications of rEBUS-guided TBB with a GS (EGS method). We also present the data from key randomized controlled trials (RCTs) of the...
Source: Expert Review of Respiratory Medicine - November 13, 2023 Category: Respiratory Medicine Authors: Yuta Takashima Masahide Oki Source Type: research

Spirometry in atrial fibrillation: What's the catch?
Expert Rev Respir Med. 2023 Nov 8. doi: 10.1080/17476348.2023.2279236. Online ahead of print.ABSTRACTINTRODUCTION: People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular events and COPD, less attention has been paid to arrhythmias, specifically atrial fibrillation (AF). AF and COPD frequently occur together, posing challenges in diagnosis and management. In this review, we describe the relationship between AF and COPD epidemiologically and physiologically, demonstrating the role of s...
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Anne E Ioannides Upasana Tayal Jennifer K Quint Source Type: research

Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
CONCLUSIONS: Short-term exposure to increased concentrations of air pollutants is an independent risk factor for IPF symptoms' aggravation.PMID:37937867 | DOI:10.1080/17476348.2023.2281992 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Konstantina Dimakopoulou Ioannis Tomos Effrosyni D Manali Spyros A Papiris Anna Karakatsani Source Type: research

Spirometry in atrial fibrillation: What's the catch?
Expert Rev Respir Med. 2023 Nov 8. doi: 10.1080/17476348.2023.2279236. Online ahead of print.ABSTRACTINTRODUCTION: People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular events and COPD, less attention has been paid to arrhythmias, specifically atrial fibrillation (AF). AF and COPD frequently occur together, posing challenges in diagnosis and management. In this review, we describe the relationship between AF and COPD epidemiologically and physiologically, demonstrating the role of s...
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Anne E Ioannides Upasana Tayal Jennifer K Quint Source Type: research

Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
CONCLUSIONS: Short-term exposure to increased concentrations of air pollutants is an independent risk factor for IPF aggravation leading to appearance of cough, expectoration, wheezing and common cold.PMID:37937867 | DOI:10.1080/17476348.2023.2281992 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Konstantina Dimakopoulou Ioannis Tomos Effrosyni D Manali Spyros A Papiris Anna Karakatsani Source Type: research

Spirometry in atrial fibrillation: What's the catch?
Expert Rev Respir Med. 2023 Nov 8. doi: 10.1080/17476348.2023.2279236. Online ahead of print.ABSTRACTINTRODUCTION: People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular events and COPD, less attention has been paid to arrhythmias, specifically atrial fibrillation (AF). AF and COPD frequently occur together, posing challenges in diagnosis and management. In this review, we describe the relationship between AF and COPD epidemiologically and physiologically, demonstrating the role of s...
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Anne E Ioannides Upasana Tayal Jennifer K Quint Source Type: research

Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
CONCLUSIONS: Short-term exposure to increased concentrations of air pollutants is an independent risk factor for IPF aggravation leading to appearance of cough, expectoration, wheezing and common cold.PMID:37937867 | DOI:10.1080/17476348.2023.2281992 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Konstantina Dimakopoulou Ioannis Tomos Effrosyni D Manali Spyros A Papiris Anna Karakatsani Source Type: research

Spirometry in atrial fibrillation: What's the catch?
Expert Rev Respir Med. 2023 Nov 8. doi: 10.1080/17476348.2023.2279236. Online ahead of print.ABSTRACTINTRODUCTION: People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular events and COPD, less attention has been paid to arrhythmias, specifically atrial fibrillation (AF). AF and COPD frequently occur together, posing challenges in diagnosis and management. In this review, we describe the relationship between AF and COPD epidemiologically and physiologically, demonstrating the role of s...
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Anne E Ioannides Upasana Tayal Jennifer K Quint Source Type: research

Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
CONCLUSIONS: Short-term exposure to increased concentrations of air pollutants is an independent risk factor for IPF aggravation leading to appearance of cough, expectoration, wheezing and common cold.PMID:37937867 | DOI:10.1080/17476348.2023.2281992 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Konstantina Dimakopoulou Ioannis Tomos Effrosyni D Manali Spyros A Papiris Anna Karakatsani Source Type: research

Spirometry in atrial fibrillation: What's the catch?
Expert Rev Respir Med. 2023 Nov 8. doi: 10.1080/17476348.2023.2279236. Online ahead of print.ABSTRACTINTRODUCTION: People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular events and COPD, less attention has been paid to arrhythmias, specifically atrial fibrillation (AF). AF and COPD frequently occur together, posing challenges in diagnosis and management. In this review, we describe the relationship between AF and COPD epidemiologically and physiologically, demonstrating the role of s...
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Anne E Ioannides Upasana Tayal Jennifer K Quint Source Type: research

Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis
CONCLUSIONS: Short-term exposure to increased concentrations of air pollutants is an independent risk factor for IPF aggravation leading to appearance of cough, expectoration, wheezing and common cold.PMID:37937867 | DOI:10.1080/17476348.2023.2281992 (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - November 8, 2023 Category: Respiratory Medicine Authors: Konstantina Dimakopoulou Ioannis Tomos Effrosyni D Manali Spyros A Papiris Anna Karakatsani Source Type: research

Interactions between calcium regulatory pathways and mechanosensitive channels in airways
Expert Rev Respir Med. 2023 Oct 31:1-15. doi: 10.1080/17476348.2023.2276732. Online ahead of print.ABSTRACTINTRODUCTION: Asthma is a chronic lung disease influenced by environmental and inflammatory triggers and involving complex signaling pathways across resident airway cells such as epithelium, airway smooth muscle, fibroblasts, and immune cells. While our understanding of asthma pathophysiology is continually progressing, there is a growing realization that cellular microdomains play critical roles in mediating signaling relevant to asthma in the context of contractility and remodeling. Mechanosensitive pathways are inc...
Source: Expert Review of Respiratory Medicine - October 31, 2023 Category: Respiratory Medicine Authors: Yang Yao Niyati A Borkar Mengning Zheng Shengyu Wang Christina M Pabelick Elizabeth R Vogel Y S Prakash Source Type: research