Expert Review of Molecular Diagnostics 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Molecular biomarkers of diffuse axonal injury: recent advances and future perspectives
Expert Rev Mol Diagn. 2024 Jan 5:1-9. doi: 10.1080/14737159.2024.2303319. Online ahead of print.ABSTRACTINTRODUCTION: Diffuse axonal injury (DAI), with high mortality and morbidity both in children and adults, is one of the most severe pathological consequences of traumatic brain injury. Currently, clinical diagnosis, disease assessment, disability identification, and postmortem diagnosis of DAI is mainly limited by the absent of specific molecular biomarkers.AREAS COVERED: In this review, we first introduce the pathophysiology of DAI, summarized the reported biomarkers in previous animal and human studies, and then the mo...
Source: Expert Review of Molecular Diagnostics - January 6, 2024 Category: Laboratory Medicine Authors: Youyou Zhang Zhaoyang Li Hui Wang Zhiyong Pei Shuquan Zhao Source Type: research
Molecular biomarkers of diffuse axonal injury: recent advances and future perspectives
Expert Rev Mol Diagn. 2024 Jan 5. doi: 10.1080/14737159.2024.2303319. Online ahead of print.ABSTRACTINTRODUCTION: Diffuse axonal injury (DAI), with high mortality and morbidity both in children and adults, is one of the most severe pathological consequences of traumatic brain injury. Currently, clinical diagnosis, disease assessment, disability identification, and postmortem diagnosis of DAI is mainly limited by the absent of specific molecular biomarkers.AREAS COVERED: In this review, we first introduce the pathophysiology of DAI, summarized the reported biomarkers in previous animal and human studies, and then the molecu...
Source: Expert Review of Molecular Diagnostics - January 6, 2024 Category: Laboratory Medicine Authors: Youyou Zhang Zhaoyang Li Hui Wang Zhiyong Pei Shuquan Zhao Source Type: research
We have reached single-visit testing, diagnosis, and treatment for hepatitis C infection, now what?
Expert Rev Mol Diagn. 2024 Jan 4:1-15. doi: 10.1080/14737159.2023.2292645. Online ahead of print.ABSTRACTINTRODUCTION: Progress toward hepatitis C virus (HCV) elimination is impeded by low testing and treatment due to the current diagnostic pathway requiring multiple visits leading to loss to follow-up. Point-of-care testing technologies capable of detecting current HCV infection in one hour are a 'game-changer.' These tests enable diagnosis and treatment in a single visit, overcoming the barrier of multiple visits that frequently leads to loss to follow-up. Combining point-of-care HCV antibody and RNA tests should improve...
Source: Expert Review of Molecular Diagnostics - January 4, 2024 Category: Laboratory Medicine Authors: Jason Grebely Susan Matthews Louise M Causer Jordan J Feld Philip Cunningham Gregory J Dore Tanya L Applegate Source Type: research
Utilization and outcomes of the 21-gene recurrence score in de novo metastatic breast cancer
CONCLUSIONS: The 21-gene RS assay is an important prognostic factor in patients with dnMBC.PMID:38166613 | DOI:10.1080/14737159.2024.2301940 (Source: Expert Review of Molecular Diagnostics)
Source: Expert Review of Molecular Diagnostics - January 3, 2024 Category: Laboratory Medicine Authors: Shi-Ping Yang Ke Liu Yang Li Guan-Qiao Li Jia-Yi Li Yu-Yi Lin San-Gang Wu Source Type: research
Molecular and epigenetic mechanisms governing ocular surface squamous neoplasia: opportunities for diagnostics
Expert Rev Mol Diagn. 2023 Dec 22:1-15. doi: 10.1080/14737159.2023.2298681. Online ahead of print.ABSTRACTINTRODUCTION: Ocular surface squamous neoplasia (OSSN) is the most common ocular malignancy; the pathophysiology is influenced by molecular, genetic, and epigenetic mechanisms. The incidence of OSSN is associated with the anatomy and physiology of the ocular surface, limbal stem cell configuration, limbal vulnerability, cancer stem cells, dysplasia, neoplasia, angiogenesis, invasion, and metastasis. The key etiological factors involved are human papillomavirus (HPV), human immunodeficiency virus (HIV), immunosuppressio...
Source: Expert Review of Molecular Diagnostics - December 22, 2023 Category: Laboratory Medicine Authors: Bharat Gurnani Kirandeep Kaur Source Type: research
Molecular and epigenetic mechanisms governing ocular surface squamous neoplasia: opportunities for diagnostics
Expert Rev Mol Diagn. 2023 Dec 22. doi: 10.1080/14737159.2023.2298681. Online ahead of print.ABSTRACTINTRODUCTION: Ocular surface squamous neoplasia (OSSN) is the most common ocular malignancy; the pathophysiology is influenced by molecular, genetic, and epigenetic mechanisms. The incidence of OSSN is associated with the anatomy and physiology of the ocular surface, limbal stem cell configuration, limbal vulnerability, cancer stem cells, dysplasia, neoplasia, angiogenesis, invasion, and metastasis. The key etiological factors involved are human papillomavirus (HPV), human immunodeficiency virus (HIV), immunosuppression, p5...
Source: Expert Review of Molecular Diagnostics - December 22, 2023 Category: Laboratory Medicine Authors: Bharat Gurnani Kirandeep Kaur Source Type: research
