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What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Nov 21:1-15. doi: 10.1080/14779072.2023.2286011. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management of athe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Nov 21:1-15. doi: 10.1080/14779072.2023.2286011. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management of athe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Nov 21:1-15. doi: 10.1080/14779072.2023.2286011. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management of athe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Nov 21:1-15. doi: 10.1080/14779072.2023.2286011. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management of athe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Nov 21:1-15. doi: 10.1080/14779072.2023.2286011. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management of athe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research