Trends and cardiovascular outcomes of Takotsubo syndrome with cardiogenic shock vs. mixed cardiogenic and septic shock: a nationwide propensity matched analysis
CONCLUSION: MS in the setting of TTS have higher rates of in-hospital mortality, AKI, and pressor requirements.PMID:38105722 | DOI:10.1080/14779072.2023.2295378 (Source: Expert Review of Cardiovascular Therapy)
Source: Expert Review of Cardiovascular Therapy - December 18, 2023 Category: Cardiology Authors: Sadaf Fakhra Mohammed Faisaluddin Yasar Sattar Danielle DeCicco Asmaa Ahmed Neel Patel Senthil Balasubramanian Dipesh Ludhwani Hassan Masood Sameer Raina Karthik Gonuguntla Scott C Feitell Tushar Tarun Sudarshan Balla Source Type: research

Risk factors modification in atrial fibrillation: a brief review
Expert Rev Cardiovasc Ther. 2023 Dec 18:1-6. doi: 10.1080/14779072.2023.2294728. Online ahead of print.ABSTRACTINTRODUCTION: Atrial fibrillation (AF) is a supraventricular arrhythmia characterized by fibrillatory waves in the atria with an irregular ventricular rhythm. It is the most common arrhythmia treated in clinical practice. AF is associated with approximately five-fold increase in risk of cerebrovascular accident (stroke) and two-fold increase in cognitive dysfunction and all-cause mortality.AREAS COVERED: Multiple risk factors have been identified for development of AF including age, hypertension, diabetes, and obe...
Source: Expert Review of Cardiovascular Therapy - December 18, 2023 Category: Cardiology Authors: Sukhbir Randhawa Subrat Da Wilbert S Aronow Source Type: research

Trends and cardiovascular outcomes of Takotsubo syndrome with cardiogenic shock vs. mixed cardiogenic and septic shock: a nationwide propensity matched analysis
CONCLUSION: MS in the setting of TTS have higher rates of in-hospital mortality, AKI, and pressor requirements.PMID:38105722 | DOI:10.1080/14779072.2023.2295378 (Source: Expert Review of Cardiovascular Therapy)
Source: Expert Review of Cardiovascular Therapy - December 18, 2023 Category: Cardiology Authors: Sadaf Fakhra Mohammed Faisaluddin Yasar Sattar Danielle DeCicco Asmaa Ahmed Neel Patel Senthil Balasubramanian Dipesh Ludhwani Hassan Masood Sameer Raina Karthik Gonuguntla Scott C Feitell Tushar Tarun Sudarshan Balla Source Type: research

Managing older people with atrial fibrillation and preventing stroke: a review of anticoagulation approaches
Expert Rev Cardiovasc Ther. 2023 Jul-Dec;21(12):963-983. doi: 10.1080/14779072.2023.2276892. Epub 2023 Dec 13.ABSTRACTINTRODUCTION: Oral anticoagulants (OACs) are the cornerstone of stroke prevention in atrial fibrillation (AF), but prescribing decisions in older people are complicated. Clinicians must assess the net clinical benefit of OAC in the context of multiple chronic conditions, polypharmacy, frailty and life expectancy. The under-representation of high-risk, older adult sub-populations in clinical trials presents the challenge of choosing the right OAC, where a 'one-size-fits-all' approach cannot be taken.AREAS CO...
Source: Expert Review of Cardiovascular Therapy - December 13, 2023 Category: Cardiology Authors: Leona A Verma Peter E Penson Asangaedem Akpan Gregory Y H Lip Deirdre A Lane Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Jul-Dec;21(11):763-777. doi: 10.1080/14779072.2023.2286011. Epub 2023 Dec 10.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management o...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Jul-Dec;21(11):763-777. doi: 10.1080/14779072.2023.2286011. Epub 2023 Dec 10.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management o...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research

Contemporary applications of multimodality imaging in infective endocarditis
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-13. doi: 10.1080/14779072.2023.2288152. Online ahead of print.ABSTRACTINTRODUCTION: Infective endocarditis (IE) is an increasingly important condition with significant morbidity and mortality. With advancements in cardiovascular interventions including prosthetic valve implantation and utilization of intracardiac devices, the prevalence of IE is rising in the modern era. Early detection and management of this condition are critical.AREAS COVERED: This review presents a contemporary review of the applications of multi-modality imaging in IE, taking a comparative approach of the vari...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Mohamed Khayata Alejandro Sanchez Nadales Bo Xu Source Type: research

What are the benefits and drawbacks of statins in carotid artery disease? A perspective review
Expert Rev Cardiovasc Ther. 2023 Jul-Dec;21(11):763-777. doi: 10.1080/14779072.2023.2286011. Epub 2023 Dec 10.ABSTRACTINTRODUCTION: The prevalence of carotid artery stenosis in the general population is approximately 3%, but approximately 20% among people with acute ischemic stroke. Statins are recommended by multiple international guidelines as the drug of choice for lipid control in people with asymptomatic or symptomatic carotid artery stenosis due to their lipid-lowering and other pleiotropic effects.AREAS COVERED: This review discusses the guidelines for statin usage as a cornerstone in the prevention and management o...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Shreef Said Alan Dardik Cassius Iyad Ochoa Chaar Source Type: research

PCSK9 inhibitors: current status and emerging frontiers in lipid control
Expert Rev Cardiovasc Ther. 2023 Nov 23:1-18. doi: 10.1080/14779072.2023.2288169. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, imposing substantial healthcare economic burdens. Among the modifiable risk factors, hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (LDL-C), plays a pivotal role in ASCVD development. Novel therapies such as PCSK9 (Proprotein Convertase Subtilisin/Kexin type 9) inhibitors are emerging to address this concern. These inhibitors offer the potential to reduce ASCVD risk by directly targe...
Source: Expert Review of Cardiovascular Therapy - November 23, 2023 Category: Cardiology Authors: Federica Agnello Maria Sara Mauro Carla Rochira Davide Landolina Simone Finocchiaro Antonio Greco Nicola Ammirabile Carmelo Raffo Placido Maria Mazzone Marco Spagnolo Giovanni Occhipinti Antonino Imbesi Daniele Giacoppo Davide Capodanno Source Type: research